GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | decreases expression | EXP | | 6480464 | CTD | Zinc deficiency results in decreased expression of JUN mRNA | PMID:21893222 | Jun | increases activity | ISO | JUN (Homo sapiens) | 6480464 | CTD | Zinc results in increased activity of JUN protein | PMID:16606632 | Jun | increases phosphorylation | ISO | JUN (Homo sapiens) | 6480464 | CTD | Zinc results in increased phosphorylation of JUN protein | PMID:16373669 | Jun | multiple interactions | ISO | Jun (Mus musculus) | 6480464 | CTD | [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein] | PMID:28035397 PMID:30768131 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | [PCI 5002 co-treated with Zinc] results in increased expression of JUN mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased activity of JUN protein] | PMID:16606632 PMID:18593933 | | ||||||||||||||||||||||
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