GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | increases expression | ISO | Jun (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of JUN mRNA; pirinixic acid results in increased expression of JUN protein | PMID:18445702 PMID:18467677 PMID:20025956 PMID:8764118 PMID:9013627 | Jun | multiple interactions | ISO | Jun (Mus musculus) | 6480464 | CTD | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of JUN mRNA; PPARA protein promotes the reaction [pirinixic acid results in increased expression of JUN mRNA] | PMID:18467677 PMID:19710929 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein] | PMID:17360982 | | ||||||||||||||||||||||
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