Gene:	Ifng ( Rattus norvegicus ) interferon gamma
Description:	an immune molecule produced by T lymphocytes in response to mitogens or antigens
Synonyms:	IFNG2;
ArrayIDs:	6635175; 1370790_at; M29317_at; AF010466_s_at; GE21305; 5887306; 5868403; A_43_P13320; 5696931; 6567830;  (details...)
Gene Type:	protein-coding
Additional Data
primer pair:	634891
Homologs
Homo sapiens: IFNG     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Ifng     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Ifng genome assembly 3.1 7 57642485 - 57646522     Rat Celera Assembly 7 50671235 - 50675273     RH 3.4 7 479.11     RGSC genome assembly v3.4 7 57621754 - 57625792     Cytogenetic 7 q22 Mus musculus Ifng Mouse genome assembly build 36.1 10 117878103 - 117882948     Cytogenetic 10 10 D2 Homo sapiens IFNG human genome assembly 12 66834816 - 66839788     Human genome assembly build 36.2 12 66834817 - 66839788     Cytogenetic 12 q14   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology interferon-gamma receptor binding,  cytokine activity (details...)
Biological Process	Note Reference inhibits bleomycin (BM)-induced pulmonary fibrosis 729234 Gene Ontology positive regulation of vitamin D biosynthetic process,  positive regulation of isotype switching to IgG isotypes,  positive regulation of smooth muscle cell apoptosis ...  (details...)
Cellular Component	Gene Ontology extracellular space,  extracellular region (details...)
Disease	Ontology Diabetes Mellitus, Experimental,  Diabetic Neuropathies,  Obesity ...  (details...)
External Links
Databases	DATABASE ID SOURCE ProDom: Interferon_gamma IPI UNIPARC: UPI000012D670 IPI KEGG Report: rno:25712 ENTREZGENE HomoloGene Group ID: 55526 ENTREZGENE Germonline: 2866 Pfam: IFN-gamma IPI KEGG Pathway: 05330 ENTREZGENE KEGG Pathway: 04060 ENTREZGENE KEGG Pathway: 05332 ENTREZGENE KEGG Pathway: 04630 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 03050 ENTREZGENE KEGG Pathway: 04140 ENTREZGENE KEGG Pathway: 05322 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04350 ENTREZGENE KEGG Pathway: 04940 ENTREZGENE InterPro: 4_helix_cytokine_core. IPI InterPro: Interferon_gamma. IPI InterPro: 4_helix_cytokine-like_core. IPI IPI: IPI00214504 IPI Ensembl Protein: ENSRNOP00000009917 IPI Gene3D-CATH: 4_helix_cytokine_core IPI Entrez Gene: Ifng ENTREZGENE PIRSF: IFN-gamma IPI UniProt: IFNG_RAT IPI Ensembl Genes: ENSRNOG00000007468 IPI RatMap: 44449 ENTREZGENE Superfamily-SCOP: 4_helix_cytokine IPI PANTHER: IFN-gamma IPI
Sequences	Nucleotide: M29317 Get FASTA Search GEO Profiles Nucleotide: X02327 Get FASTA Search GEO Profiles Nucleotide: X02326 Get FASTA Search GEO Profiles Nucleotide: X02325 Get FASTA Search GEO Profiles Nucleotide: AF010466 Get FASTA Search GEO Profiles Nucleotide: M29316 Get FASTA Search GEO Profiles Nucleotide: M29315 Get FASTA Search GEO Profiles Nucleotide: CH473960 Get FASTA Search GEO Profiles Nucleotide: NM_138880 Get FASTA Search GEO Profiles (View all 9 Nucleotide Accessions) Protein: CAA26185 Get FASTA Protein: P01581 Get FASTA Protein: AAB66352 Get FASTA Protein: CAA26188 Get FASTA Protein: AAA41362 Get FASTA Protein: EDM16596 Get FASTA Protein: NP_620235 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 10795
References
Curated References	26 references in RGD related to Ifng
Other References	40 other references at PubMed related to Ifng
Database Information
RGD ID	2866
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-JUN-02: Ifng Interferon gamma APPROVED Symbol and Name status set to approved 70586