GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | decreases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Benzene results in decreased expression of IFNG mRNA | PMID:15929907 PMID:19162166 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Benzene promotes the reaction [[[Lipopolysaccharides co-treated with IFNG protein] co-treated with CSF1 protein] results in increased chemical synthesis of Nitric Oxide] | PMID:8193360 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of IFNG; Benzene promotes the reaction [[[Lipopolysaccharides co-treated with IFNG protein] co-treated with CSF2 protein] results in increased chemical synthesis of Nitric Oxide]; Benzene promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]; Benzene promotes the reaction [IFNG protein results in increased chemical synthesis of Nitric Oxide]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with Benzene] results in increased abundance of Nitric Oxide] | PMID:22863854 PMID:7884313 PMID:8193360 | |
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