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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:28793
Term: beta-D-glucan
Definition: null
Chemical ID: MESH:D047071
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTD[beta-Glucans co-treated with resiquimod co-treated with IFNG protein] results in increased expression of IL12A mRNA; IFNG protein inhibits the reaction [beta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]]; IFNG protein inhibits the reaction [beta-Glucans results in increased expression of IL10 mRNA]; IFNG protein inhibits the reaction [beta-Glucans results in increased expression of IL10 protein]; IFNG protein inhibits the reaction [beta-Glucans results in increased expression of IL23A mRNA]; IFNG protein promotes the reaction [beta-Glucans results in increased expression of [IL12A protein binds to IL12B protein]]PMID:18490488
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