GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter] | PMID:21569788 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [MAP2K6 protein results in increased susceptibility to nickel chloride] which results in increased expression of IFNG protein; nickel chloride promotes the reaction [[[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; NOS2 protein promotes the reaction [nickel chloride promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]] | PMID:21544193 PMID:8975779 | | ||||||||||||||||||||||
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