GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | decreases secretion | ISO | Ifng (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in decreased secretion of IFNG protein | PMID:22273745 | Ifng | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Silicon Dioxide analog results in increased expression of IFNG mRNA; Silicon Dioxide results in increased expression of IFNG mRNA | PMID:25388157 PMID:29341224 | Ifng | increases secretion | ISO | Ifng (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased secretion of IFNG protein | PMID:23640035 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Silicon Dioxide co-treated with Lipopolysaccharides] results in increased secretion of IFNG protein; AHR protein affects the reaction [[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased secretion of IFNG protein]; AHR protein affects the reaction [Silicon Dioxide results in decreased secretion of IFNG protein]; IL10 protein inhibits the reaction [AHR protein affects the reaction [[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased secretion of IFNG protein]]; IL10 protein promotes the reaction [[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased secretion of IFNG protein]; IL1B protein affects the reaction [Silicon Dioxide analog results in increased expression of IFNG mRNA]; IL1B protein affects the reaction [Silicon Dioxide results in increased secretion of IFNG protein] | PMID:22273745 PMID:23640035 PMID:25388157 | |
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