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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:9143
Term: silychristin
Definition: A flavonolignan isolated from Silybum marianum and has been shown to exhibit inhibitory activities against lipoxygenase and prostaglandin synthetase.
Chemical ID: MESH:C015504
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTDsilychristin inhibits the reaction [IL1B protein results in increased expression of IFNG mRNA]; silychristin inhibits the reaction [IL1B protein results in increased secretion of IFNG protein]PMID:28914761
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