GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | affects secretion | ISO | Ifng (Mus musculus) | 6480464 | CTD | Estradiol affects the secretion of IFNG protein | PMID:12538720 | Ifng | increases secretion | ISO | Ifng (Mus musculus) | 6480464 | CTD | Estradiol results in increased secretion of IFNG protein | PMID:12711627 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of IFNG protein] | PMID:20130130 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Estradiol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of CCL2 protein]; Estradiol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of and results in increased secretion of TNF protein]; Estradiol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; Estradiol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Estradiol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] | PMID:16716911 PMID:29718165 | | ||||||||||||||||||||||
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