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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:81389
Term: Dimaprit
Definition: An imidothiocarbamic ester that has formula C6H15N3S.
Chemical ID: MESH:D017259
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngaffects expressionISOIFNG (Homo sapiens)6480464CTDDimaprit affects the expression of IFNG proteinPMID:17346280
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTDDimaprit inhibits the reaction [IL18 protein results in increased expression of IFNG protein]PMID:11752121 PMID:12364868
Ifngmultiple interactionsISOIfng (Mus musculus)6480464CTDDimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]PMID:19277450
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