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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngaffects secretionISOIFNG (Homo sapiens)6480464CTDCocaine affects the secretion of IFNG proteinPMID:9787120
Ifngdecreases expressionISOIFNG (Homo sapiens)6480464CTDCocaine results in decreased expression of IFNG proteinPMID:9787120
Ifngdecreases expressionISOIfng (Mus musculus)6480464CTDCocaine results in decreased expression of IFNG mRNA; Cocaine results in decreased expression of IFNG proteinPMID:29673861
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTD[Cocaine co-treated with Heroin] results in increased expression of IFNG proteinPMID:16766138
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