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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:31697
Term: indolin-2-one
Definition: An indolinone carrying an oxo group at position 2.
Chemical ID: MESH:C022960
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTD2-oxindole promotes the reaction [IFNG protein results in increased expression of CD274 protein]; IFNG protein inhibits the reaction [2-oxindole results in increased expression of CYP1A2 protein]PMID:36368423
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