GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | decreases expression | EXP | | 6480464 | CTD | Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein | PMID:16368244 PMID:21515370 | Ifng | multiple interactions | EXP | | 6480464 | CTD | [Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein | PMID:21515370 | Ifng | decreases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Tacrolimus results in decreased expression of IFNG protein | PMID:11407316 PMID:20967261 | Ifng | decreases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein | PMID:8986461 | Ifng | decreases secretion | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Tacrolimus results in decreased secretion of IFNG protein | PMID:11692113 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA] | PMID:1371491 PMID:24603311 PMID:29594315 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein] | PMID:10205001 | | ||||||||||||||||||||||
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