GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Air Pollutants results in increased abundance of Carbon Monoxide] which affects the methylation of IFNG gene | PMID:33603036 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein; Carbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; Carbon Monoxide inhibits the reaction [IFNG protein results in decreased expression of HMOX1 protein] | PMID:16365149 PMID:29621558 | | ||||||||||||||||||||||
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