GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | increases expression | EXP | | 6480464 | CTD | Formaldehyde results in increased expression of IFNG mRNA; Formaldehyde results in increased expression of IFNG protein | PMID:19827972 PMID:27020608 | Ifng | multiple interactions | EXP | | 6480464 | CTD | [Formaldehyde co-treated with Lipopolysaccharides] results in increased expression of IFNG mRNA; Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of IFNG mRNA]; Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IFNG protein] | PMID:25845602 PMID:27020608 | Ifng | affects expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Formaldehyde affects the expression of IFNG protein | PMID:19422874 | Ifng | decreases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Formaldehyde results in decreased expression of IFNG mRNA; Formaldehyde results in decreased expression of IFNG protein | PMID:18849615 | Ifng | decreases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Formaldehyde results in decreased expression of IFNG mRNA; Formaldehyde results in decreased expression of IFNG protein | PMID:24060340 | Ifng | increases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Formaldehyde results in increased expression of IFNG mRNA | PMID:23649840 | Ifng | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Formaldehyde results in increased expression of IFNG mRNA; Formaldehyde results in increased expression of IFNG protein | PMID:12161283 PMID:19042193 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Formaldehyde results in decreased expression of IFNG mRNA]; Formaldehyde results in increased expression of and results in increased secretion of IFNG protein | PMID:18082304 PMID:18849615 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of IFNG; [Formaldehyde co-treated with diisononyl phthalate] promotes the reaction [OVAL protein results in decreased secretion of IFNG protein]; Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IFNG protein] | PMID:15003329 PMID:22863854 PMID:29758289 | | ||||||||||||||||||||||
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