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ONTOLOGY REPORT - ANNOTATIONS

Term:acetylcholine receptor signaling pathway
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Accession:GO:0095500 term browser browse the term
Definition:The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: acetylcholine receptor signalling pathway


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acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179948 (PMID:14645660)		 Ensembl
RGD		 PMID:14645660 GO_REF:0000107 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO (PMID:17478539) RGD PMID:17478539 NCBI chr17:64,696,549...65,158,622
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:78,862,286...78,877,353
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IGI
IBA		 PMID:21540349
GO_REF:0000033		 GO_Central PMID:21540349 GO_REF:0000033, RGD:12790638 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit involved_in
acts_upstream_of_or_within		 IBA
ISO
IDA
ISS		 GO_REF:0000033
(PMID:26276394)
PMID:9882698
PMID:22593584
GO_REF:0000024
(PMID:17132685), (PMID:27698419), (PMID:29720657), (PMID:38454578)		 GO_Central
RGD
UniProt		 PMID:17132685 PMID:26276394 PMID:27698419 PMID:29720657 PMID:38454578 More... GO_REF:0000024 GO_REF:0000033, RGD:596936194, RGD:596936208 NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:64,697,741...64,704,441
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IDA
ISO		 PMID:21540349
(PMID:19230830)		 RGD PMID:19230830 PMID:21540349 RGD:12790638 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in
acts_upstream_of_or_within		 IGI
IBA
ISO
ISS		 PMID:21540349
GO_REF:0000033
(PMID:26276394)
GO_REF:0000024
(PMID:17132685), (PMID:27698419), (PMID:29720657), (PMID:38454578)		 GO_Central
RGD
UniProt		 PMID:17132685 PMID:26276394 PMID:27698419 PMID:29720657 PMID:38454578 More... GO_REF:0000024 GO_REF:0000033, RGD:12790638 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:1924574|MGI:700014 (PMID:26527617) RGD PMID:26527617 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:1856965 (PMID:19346129) RGD PMID:19346129 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981 		JBrowse link
G Ly6al1 lymphocyte antigen 6 complex, locus A like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,011,585...107,018,125
Ensembl chr 7:107,011,623...107,015,179 		JBrowse link
G Ly6c Ly6-C antigen involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,959,508...106,963,329
Ensembl chr 7:106,959,511...106,963,329 		JBrowse link
G Ly6cl1 Ly6-C antigen like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,122,197...107,163,755
Ensembl chr 7:107,011,588...107,163,788 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:26276394)
GO_REF:0000033		 RGD
GO_Central		 PMID:26276394 GO_REF:0000033 NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Ly6g6d lymphocyte antigen 6 family member G6D involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr20:3,741,973...3,752,378
Ensembl chr20:3,737,459...3,752,248 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849 		JBrowse link
G Ly6h lymphocyte antigen 6 family member H involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr 7:107,258,779...107,261,270
Ensembl chr 7:107,258,779...107,261,454 		JBrowse link
G Ly6i lymphocyte antigen 6 complex, locus I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,062,320...107,067,743
Ensembl chr 7:107,062,325...107,067,310 		JBrowse link
G Ly6m lymphocyte antigen 6 family member M involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,863,167...106,867,047
Ensembl chr 7:106,865,291...106,867,047 		JBrowse link
G Lynx1 Ly6/neurotoxin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G Pate14 prostate and testis expressed 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:34,317,553...34,319,201
Ensembl chr 8:34,317,553...34,319,164 		JBrowse link
G Pate14l1 prostate and testis expressed 14 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:36,133,954...36,135,582
Ensembl chr 8:36,133,954...36,135,519 		JBrowse link
G Psca prostate stem cell antigen involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746 		JBrowse link
G Slurp2 secreted Ly6/Plaur domain containing 2 involved_in ISO
IBA		 (PMID:27485575)
GO_REF:0000033		 RGD
GO_Central		 PMID:27485575 GO_REF:0000033 NCBI chr 7:106,627,775...106,631,655
Ensembl chr 7:106,627,775...106,631,655 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 acts_upstream_of_or_within ISO MGI:104686|MGI:1924574 (PMID:26527617) RGD PMID:26527617 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 acts_upstream_of_or_within ISO MGI:104686|MGI:700014 (PMID:26527617) RGD PMID:26527617 NCBI chr16:53,167,795...53,481,300
Ensembl chr16:46,435,237...46,626,514 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:64,696,549...65,158,622
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:7916637)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:7916637 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:8051154 GO_Central PMID:8051154 RGD:8656009 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in IDA PMID:11276227 UniProt PMID:11276227 RGD:8554712 NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IDA
ISO		 (PMID:12196552) RGD PMID:12196552 PMID:12534975 RGD:724727 NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:2155543 (PMID:9990086)
(PMID:24256733)		 RGD PMID:9990086 PMID:24256733 PMID:12534975 RGD:724727 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IDA
IMP		 PMID:1527051 RGD
UniProt		 PMID:12185001 PMID:1527051 PMID:15141107 RGD:724728, RGD:10047264, RGD:2303392 NCBI chr17:64,696,549...65,158,622
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Gnai2 G protein subunit alpha i2 acts_upstream_of_or_within ISO MGI:2152603 (PMID:11299198) RGD PMID:11299198 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO (PMID:9305844) RGD PMID:9305844 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11443111)		 UniProt
RGD		 PMID:11443111 GO_REF:0000024 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect ISO MGI:2159005 (PMID:10570150) RGD PMID:10570150 NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in ISO MGI:3770175 (PMID:16753580), (PMID:20440069) RGD PMID:16753580 PMID:20440069 NCBI chr17:64,696,549...65,158,622
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in IEA
ISO		 GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069)		 Ensembl
RGD		 PMID:20440069 GO_REF:0000107 NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q involved_in IEA
ISO		 GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069)		 Ensembl
RGD		 PMID:20440069 GO_REF:0000107 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:88031 (PMID:10570150)		 Ensembl
RGD		 PMID:10570150 GO_REF:0000107 NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:6460327|MGI:88031 (PMID:10570150), (PMID:31268747)		 Ensembl
RGD		 PMID:10570150 PMID:31268747 GO_REF:0000107 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Prkcb protein kinase C, beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:27226533)		 Ensembl
RGD		 PMID:27226533 GO_REF:0000107 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISO (PMID:18452988) RGD PMID:18452988 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      signal transduction 7262
        postsynaptic signal transduction 72
          acetylcholine receptor signaling pathway 54
            G protein-coupled acetylcholine receptor signaling pathway + 19
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        signaling 7822
          cell-cell signaling 1484
            synaptic signaling 1005
              postsynaptic signal transduction 72
                acetylcholine receptor signaling pathway 54
                  G protein-coupled acetylcholine receptor signaling pathway + 19
paths to the root