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ONTOLOGY REPORT - ANNOTATIONS

Term:protein serine/threonine kinase activator activity
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Accession:GO:0043539 term browser browse the term
Definition:Binds to and increases the activity of a protein serine/threonine kinase.
Synonyms:exact_synonym: protein ser/thr kinase activator activity


show annotations for term's descendants           Sort by:
protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 enables IGI
IMP		 (PMID:20667975) MGI PMID:20667975 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing enables IDA (PMID:20667975) MGI PMID:20667975 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 1:59,201,915...59,276,390
Ensembl chr 1:59,202,085...59,276,390 		JBrowse link
G Atg13 autophagy related 13 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921 		JBrowse link
G Axin1 axin 1 enables ISO (PMID:9601641) BHF-UCL PMID:9601641 NCBI chr17:26,350,294...26,414,784
Ensembl chr17:26,357,662...26,414,785 		JBrowse link
G Bmp2 bone morphogenetic protein 2 enables IDA
ISO		 (PMID:21976273), (PMID:7798324) MGI
GO_Central		 PMID:7798324 PMID:21976273 GO_REF:0000119 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Bmp4 bone morphogenetic protein 4 enables IEA Ensembl GO_REF:0000107 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp7 bone morphogenetic protein 7 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Cab39 calcium binding protein 39 enables IBA
ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297 		JBrowse link
G Cab39l calcium binding protein 39-like enables IBA GO_Central GO_REF:0000033 NCBI chr14:59,678,400...59,786,353
Ensembl chr14:59,678,421...59,823,213 		JBrowse link
G Calm1 calmodulin 1 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073 		JBrowse link
G Calm2 calmodulin 2 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363 		JBrowse link
G Calm3 calmodulin 3 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:16,649,304...16,657,957
Ensembl chr 7:16,649,304...16,658,039 		JBrowse link
G Ccdc88a coiled coil domain containing 88A enables IDA (PMID:15753085) UniProt PMID:15753085 NCBI chr11:29,323,521...29,460,808
Ensembl chr11:29,323,658...29,460,808 		JBrowse link
G Ccnd1 cyclin D1 enables ISS UniProt GO_REF:0000024 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnd2 cyclin D2 enables ISO (PMID:8114739) BHF-UCL PMID:8114739 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156 		JBrowse link
G Ccnd3 cyclin D3 enables ISO (PMID:8114739) BHF-UCL PMID:8114739 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616 		JBrowse link
G Cd40lg CD40 ligand enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 enables ISO
ISS		 RGD
GO_Central
UniProt		 PMID:8662984 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 RGD:632374 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010 		JBrowse link
G D1Pas1 DNA segment, Chr 1, Pasteur Institute 1 enables ISO GO_Central GO_REF:0000119 NCBI chr 1:186,699,613...186,702,824
Ensembl chr 1:186,699,613...186,702,824 		JBrowse link
G Dab2ip disabled 2 interacting protein enables ISS UniProt GO_REF:0000024 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006 		JBrowse link
G Dazap2 DAZ associated protein 2 enables IDA (PMID:18762249) WB PMID:18762249 NCBI chr15:100,513,543...100,518,642
Ensembl chr15:100,513,230...100,518,642 		JBrowse link
G Dbf4 DBF4 zinc finger enables IBA GO_Central GO_REF:0000033 NCBI chr 5:8,446,969...8,472,789
Ensembl chr 5:8,446,973...8,472,716 		JBrowse link
G Ddx3x DEAD box helicase 3, X-linked enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:13,147,261...13,160,222
Ensembl chr  X:13,147,209...13,160,291 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 enables ISS
ISO
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000119 NCBI chr18:38,383,302...38,395,682
Ensembl chr18:38,383,308...38,398,514 		JBrowse link
G Etaa1 Ewing tumor-associated antigen 1 enables IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr11:17,888,753...17,903,875
Ensembl chr11:17,888,756...17,903,875 		JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase enables IBA
ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr11:109,563,752...109,613,989
Ensembl chr11:109,560,575...109,613,105 		JBrowse link
G Fermt2 fermitin family member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr14:45,696,252...45,767,767
Ensembl chr14:45,696,252...45,767,575 		JBrowse link
G Gcn1 GCN1 activator of EIF2AK4 enables IDA
IMP		 (PMID:24333428)
(PMID:32324833)		 UniProt PMID:24333428 PMID:32324833 NCBI chr 5:115,703,177...115,760,713
Ensembl chr 5:115,703,313...115,760,713 		JBrowse link
G Gdf2 growth differentiation factor 2 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr14:33,662,996...33,669,155
Ensembl chr14:33,662,996...33,669,155 		JBrowse link
G Igf1 insulin-like growth factor 1 enables ISO GO_Central GO_REF:0000096 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf2 insulin-like growth factor 2 enables IBA
IMP		 (PMID:20032056) GO_Central
BHF-UCL		 PMID:20032056 GO_REF:0000033 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Igtp interferon gamma induced GTPase enables ISO GO_Central GO_REF:0000119 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 enables ISO GO_Central GO_REF:0000119 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 enables ISO GO_Central GO_REF:0000119 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 enables IDA (PMID:25065622) UniProt PMID:25065622 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772 		JBrowse link
G Ltf lactotransferrin enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 enables IMP (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 enables IMP (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chr16:21,643,923...21,752,189
Ensembl chr16:21,613,096...21,752,189 		JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:24,692,524...24,698,722
Ensembl chr17:24,692,525...24,698,052 		JBrowse link
G Mob1a MOB kinase activator 1A enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:83,303,016...83,320,758
Ensembl chr 6:83,302,998...83,320,758 		JBrowse link
G Mob1b MOB kinase activator 1B enables ISO GO_Central GO_REF:0000119 NCBI chr 5:88,868,730...88,906,314
Ensembl chr 5:88,868,714...88,912,079 		JBrowse link
G Mstn myostatin enables IEA Ensembl GO_REF:0000107 NCBI chr 1:53,100,799...53,107,238
Ensembl chr 1:53,100,799...53,107,238 		JBrowse link
G Mtcp1 mature T cell proliferation 1 enables IEA
IBA
ISO		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:74,454,048...74,460,190
Ensembl chr  X:74,454,050...74,460,194 		JBrowse link
G Nbn nibrin enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 enables ISO Akt (protein kinase B); Ser473, Thr308 RGD
GO_Central		 PMID:15023862 GO_REF:0000096 RGD:1642719 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 enables IBA
IEA
ISO		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:65,121,918...65,146,502
Ensembl chr 9:65,102,635...65,146,506 		JBrowse link
G Parp6 poly (ADP-ribose) polymerase family, member 6 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:59,524,473...59,557,573
Ensembl chr 9:59,524,567...59,557,568 		JBrowse link
G Parp8 poly (ADP-ribose) polymerase family, member 8 enables IBA GO_Central GO_REF:0000033 NCBI chr13:116,987,378...117,162,549
Ensembl chr13:116,991,356...117,162,073 		JBrowse link
G Pim1 proviral integration site 1 enables ISO GO_Central GO_REF:0000119 NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086 		JBrowse link
G Rad50 RAD50 double strand break repair protein enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rheb Ras homolog enriched in brain enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:25,007,821...25,047,359
Ensembl chr 5:25,007,821...25,047,622 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 enables IEA
IBA
ISO		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882 		JBrowse link
G Samd15 sterile alpha motif domain containing 15 enables IBA GO_Central GO_REF:0000033 NCBI chr12:87,247,240...87,260,315
Ensembl chr12:87,246,497...87,260,315 		JBrowse link
G Sav1 salvador family WW domain containing 1 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:70,011,786...70,033,864
Ensembl chr12:70,011,786...70,033,776 		JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 enables IGI
IMP		 (PMID:20667975)
(PMID:19560442)		 MGI PMID:19560442 PMID:20667975 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr14:106,129,381...106,134,559
Ensembl chr14:106,129,381...106,134,253 		JBrowse link
G Strada STE20-related kinase adaptor alpha enables IBA
IEA
ISO		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr11:106,053,739...106,084,460
Ensembl chr11:106,054,156...106,092,994 		JBrowse link
G Stradb STE20-related kinase adaptor beta enables IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:59,012,681...59,034,281
Ensembl chr 1:59,012,681...59,034,874 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 enables ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr15:80,017,333...80,045,908
Ensembl chr15:80,017,328...80,045,908 		JBrowse link
G Taok1 TAO kinase 1 enables ISO GO_Central GO_REF:0000096 NCBI chr11:77,419,988...77,516,185
Ensembl chr11:77,419,988...77,498,641 		JBrowse link
G Tcl1 T cell lymphoma breakpoint 1 enables IEA
IBA
ISO		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,183,012...105,188,996
Ensembl chr12:105,183,009...105,189,052 		JBrowse link
G Tcl1b1 T cell leukemia/lymphoma 1B, 1 enables ISO
IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,125,963...105,132,884
Ensembl chr12:105,125,949...105,132,884 		JBrowse link
G Tcl1b2 T cell leukemia/lymphoma 1B, 2 enables ISO
IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,113,278...105,121,484
Ensembl chr12:105,112,273...105,121,484 		JBrowse link
G Tcl1b3 T cell leukemia/lymphoma 1B, 3 enables ISO
IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,157,304...105,161,658
Ensembl chr12:105,157,302...105,161,871 		JBrowse link
G Tcl1b4 T cell leukemia/lymphoma 1B, 4 enables ISO
IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,168,654...105,173,252
Ensembl chr12:105,168,216...105,173,252 		JBrowse link
G Tcl1b5 T cell leukemia/lymphoma 1B, 5 enables IEA
IBA
ISO		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr12:105,142,603...105,147,404
Ensembl chr12:105,142,603...105,147,404 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 enables IDA (PMID:25065622) UniProt PMID:25065622 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 enables ISO (PMID:25749521) BHF-UCL PMID:25749521 NCBI chr 2:84,878,356...84,903,392
Ensembl chr 2:84,878,366...84,903,392 		JBrowse link
G Topbp1 topoisomerase (DNA) II binding protein 1 enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 9:103,182,351...103,227,627
Ensembl chr 9:103,182,414...103,227,627 		JBrowse link
cyclin-dependent protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnb1-ps cyclin B1, pseudogene enables ISO GO_Central GO_REF:0000119 NCBI chr 7:41,755,193...41,756,726
Ensembl chr 7:41,755,323...41,756,609 		JBrowse link
G Ccnd1 cyclin D1 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnd2 cyclin D2 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156 		JBrowse link
G Ccnd3 cyclin D3 enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616 		JBrowse link
G Ccnk cyclin K enables IBA GO_Central GO_REF:0000033 NCBI chr12:108,145,543...108,170,252
Ensembl chr12:108,145,838...108,169,618 		JBrowse link
G Ccnt1 cyclin T1 enables ISO
ISS
IBA		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804 		JBrowse link
G Ccnt2 cyclin T2 enables IBA GO_Central GO_REF:0000033 NCBI chr 1:127,701,901...127,732,574
Ensembl chr 1:127,701,901...127,735,798 		JBrowse link
G Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 enables ISO
IMP
TAS
IBA		 (PMID:11517264)
(PMID:12516540)		 RGD
MGI
GO_Central		 PMID:8662984 PMID:11517264 PMID:12516540 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:632374 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010 		JBrowse link
G Cdk5r2 cyclin dependent kinase 5, regulatory subunit 2 enables IMP
TAS
IDA
IBA		 (PMID:11517264)
(PMID:12516540)
(PMID:10683146)		 MGI
ARUK-UCL
GO_Central		 PMID:10683146 PMID:11517264 PMID:12516540 GO_REF:0000033 NCBI chr 1:74,894,188...74,896,891
Ensembl chr 1:74,894,093...74,896,891 		JBrowse link
G Cks1b CDC28 protein kinase 1b enables IBA GO_Central GO_REF:0000033 NCBI chr 3:89,322,779...89,325,598
Ensembl chr 3:89,322,779...89,325,690 		JBrowse link
G Cks1brt CDC28 protein kinase 1b, retrogene enables IBA GO_Central GO_REF:0000033 NCBI chr 8:85,878,553...85,900,251
Ensembl chr 8:85,878,553...85,900,251 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 enables IBA GO_Central GO_REF:0000033 NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696 		JBrowse link
G Mnat1 menage a trois 1 enables IEA InterPro GO_REF:0000002 NCBI chr12:73,158,957...73,320,762
Ensembl chr12:73,170,491...73,320,762 		JBrowse link
G Tex24 testis expressed gene 24 enables IBA GO_Central GO_REF:0000033 NCBI chr 8:27,834,351...27,839,458
Ensembl chr 8:27,806,342...27,839,222 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28771
    molecular function regulator activity 2315
      enzyme regulator activity 1355
        enzyme activator activity 613
          kinase activator activity 164
            protein kinase activator activity 153
              protein serine/threonine kinase activator activity 84
                cyclin-dependent protein serine/threonine kinase activator activity 15
                eukaryotic elongation factor-2 kinase activator activity 0
paths to the root