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Gene: Topbp1 (topoisomerase (DNA) II binding protein 1) Mus musculus
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Symbol: Topbp1
Name: topoisomerase (DNA) II binding protein 1
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); reciprocal meiotic recombination (ortholog); response to ionizing radiation (ortholog); ASSOCIATED WITH abnormal cell cycle; abnormal cell physiology; abnormal cerebral cortex morphology; ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN chromosome; condensed nuclear chromosome; male germ cell nucleus; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1110031N14Rik; 2810429C13Rik; AI256758; D430026L04Rik; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; mKIAA0259; topoisomerase (DNA) II beta binding protein
Orthologs:
Homo sapiens (human) : TOPBP1 (DNA topoisomerase II binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Topbp1 (DNA topoisomerase II binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Topbp1 (DNA topoisomerase II binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TOPBP1 (DNA topoisomerase II binding protein 1)
Canis lupus familiaris (dog) : TOPBP1 (DNA topoisomerase II binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Topbp1 (DNA topoisomerase II binding protein 1)
Sus scrofa (pig) : TOPBP1 (DNA topoisomerase II binding protein 1)
more info ...
Related Pseudogenes: Gm18831   Topbp1-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389103,305,167 - 103,350,428 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379103,207,657 - 103,252,758 (+)NCBIGRCm37mm9NCBIm37
MGSCv369103,163,477 - 103,208,578 (+)NCBImm8
Celera9102,854,061 - 102,901,479 (+)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Topbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321300
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.