Cks1brt (CDC28 protein kinase 1b, retrogene) - Rat Genome Database
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Gene: Cks1brt (CDC28 protein kinase 1b, retrogene) Mus musculus
Analyze
No known orthologs.
Symbol: Cks1brt
Name: CDC28 protein kinase 1b, retrogene
RGD ID: 1617079
MGI Page MGI
Description: Predicted to have several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to localize to SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS1B (CDC28 protein kinase regulatory subunit 1B); INTERACTS WITH carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EG624855; Gm6531; predicted gene 6531
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,878,553 - 85,900,251 (+)NCBIGRCm39mm39
GRCm38885,151,924 - 85,173,622 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,151,924 - 85,173,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,675,823 - 87,697,521 (+)NCBIGRCm37mm9NCBIm37
MGSCv36888,042,029 - 88,063,727 (+)NCBImm8
Celera889,440,026 - 89,465,858 (+)NCBICelera
Cytogenetic Map8C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21873635  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse
1301766Desp1_mdespair 1 (mouse)Not determined884759576118759741Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:427
Count of miRNA genes:328
Interacting mature miRNAs:361
Transcripts:ENSMUST00000076896
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000076896   ⟹   ENSMUSP00000076162
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,171,322 - 85,173,622 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211617   ⟹   ENSMUSP00000147685
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,151,924 - 85,173,622 (+)Ensembl
RefSeq Acc Id: NM_001037922   ⟹   NP_001033011
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39885,878,553 - 85,900,251 (+)NCBI
GRCm38885,151,924 - 85,173,622 (+)ENTREZGENE
MGSCv37887,675,823 - 87,697,521 (+)RGD
Celera889,440,026 - 89,465,858 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001033011 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47101 (Get FASTA)   NCBI Sequence Viewer  
  AAI47102 (Get FASTA)   NCBI Sequence Viewer  
  BAE25818 (Get FASTA)   NCBI Sequence Viewer  
  EDL11002 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001033011   ⟸   NM_001037922
- UniProtKB: Q3UNC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147685   ⟸   ENSMUST00000211617
RefSeq Acc Id: ENSMUSP00000076162   ⟸   ENSMUST00000076896

Promoters
RGD ID:8667751
Promoter ID:EPDNEW_M11907
Type:multiple initiation site
Name:Cks1brt_1
Description:Mus musculus CDC28 protein kinase 1b, retrogene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38885,171,526 - 85,171,586EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3643620 AgrOrtholog
Ensembl Genes ENSMUSG00000062687 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000076162 UniProtKB/TrEMBL
  ENSMUSP00000147685 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000076896 UniProtKB/TrEMBL
  ENSMUST00000211617 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.170.10 UniProtKB/TrEMBL
InterPro Cyclin-dep_kinase_reg-sub UniProtKB/TrEMBL
  Cyclin-dep_kinase_reg-sub_sf UniProtKB/TrEMBL
KEGG Report mmu:624855 UniProtKB/TrEMBL
MGD MGI:3643620 ENTREZGENE
NCBI Gene 624855 ENTREZGENE
Pfam CKS UniProtKB/TrEMBL
PhenoGen Cks1brt PhenoGen
PRINTS CYCLINKINASE UniProtKB/TrEMBL
PROSITE CKS_1 UniProtKB/TrEMBL
SMART CKS UniProtKB/TrEMBL
Superfamily-SCOP Cyc_dep_kin_rsub UniProtKB/TrEMBL
UniGene Mm.390061 ENTREZGENE
UniProt Q3UNC9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-21 Cks1brt  CDC28 protein kinase 1b, retrogene  Gm6531  predicted gene 6531  Symbol and/or name change 5135510 APPROVED