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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA modification
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Accession:GO:0006400 term browser browse the term
Definition:The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
Comment:The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.
Synonyms:narrow_synonym: tRNA editing
 alt_id: GO:0016549


show annotations for term's descendants           Sort by:
tRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07005588.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002
G Aars1 alanyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:16906134)
(MGI:5609717|PMID:25422440), (MGI:6159204|PMID:29769718)		 UniProt
RGD		 PMID:16906134 PMID:25422440 PMID:29769718 GO_REF:0000024 MGI:5609717 MGI:6159204 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Ankrd16 ankyrin repeat domain 16 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6159204|PMID:29769718)		 UniProt
RGD		 PMID:29769718 GO_REF:0000024 MGI:6159204 NCBI chr17:66,735,325...66,748,533
Ensembl chr17:66,737,261...66,748,533 		JBrowse link
G B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 involved_in IDA
ISO		 PMID:37992713
(PMID:37992713)		 RGD PMID:37992713 PMID:37992713 RGD:401966881 NCBI chr10:106,870,237...106,933,723
Ensembl chr10:106,873,169...106,933,637 		JBrowse link
G Dtwd1 DTW domain containing 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:31804502)		 UniProt
GO_Central
Ensembl
RGD		 PMID:31804502 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:113,392,402...113,409,322
Ensembl chr 3:113,392,457...113,408,105 		JBrowse link
G Dtwd2 DTW domain containing 2 involved_in ISO (PMID:31804502) RGD PMID:31804502 NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832 		JBrowse link
G Elp5 elongator acetyltransferase complex subunit 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,692,526...54,704,255
Ensembl chr10:54,692,530...54,704,923 		JBrowse link
G Gtdc1 glycosyltransferase-like domain containing 1 involved_in IDA
ISO
IEA		 PMID:37992713
(PMID:37992713)
GO_REF:0000107		 RGD
Ensembl		 PMID:37992713 PMID:37992713 GO_REF:0000107, RGD:401966881 NCBI chr 3:28,766,640...29,161,668
Ensembl chr 3:28,766,645...29,162,271 		JBrowse link
G Mettl1 methyltransferase 1, tRNA methylguanosine involved_in ISO (PMID:12403464), (PMID:15861136) RGD PMID:12403464 PMID:15861136 NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
G Mettl2 methyltransferase like 2 involved_in ISO (PMID:34268557) RGD PMID:34268557 NCBI chr10:90,095,527...90,109,354
Ensembl chr10:90,095,527...90,119,528 		JBrowse link
G Mettl6 methyltransferase 6, tRNA N3-cytidine involved_in ISO (PMID:34268557) RGD PMID:34268557 NCBI chr16:6,683,820...6,699,013
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Nsun6 NOP2/Sun RNA methyltransferase 6 involved_in ISO (PMID:37226891) RGD PMID:37226891 NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006 		JBrowse link
G Osgep O-sialoglycoprotein endopeptidase involved_in ISO (PMID:28805828) RGD PMID:28805828 NCBI chr15:24,137,149...24,144,568
Ensembl chr15:24,137,153...24,144,568 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:34268557)		 Ensembl
RGD		 PMID:34268557 GO_REF:0000107 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000104		 UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687 		JBrowse link
G Thumpd1 THUMP domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:174,078,875...174,084,915
Ensembl chr 1:174,078,878...174,084,937 		JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 involved_in ISO (PMID:16424344) RGD PMID:16424344 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439 		JBrowse link
G Trit1 tRNA isopentenyltransferase 1 involved_in ISO
IBA		 (PMID:24126054)
GO_REF:0000033
(MGI:5476410|PMID:23289710)		 RGD
GO_Central		 PMID:23289710 PMID:24126054 GO_REF:0000033 MGI:5476410 NCBI chr 5:135,293,472...135,341,522
Ensembl chr 5:135,295,330...135,338,764 		JBrowse link
G Trub1 TruB pseudouridine synthase family member 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:32926445)		 UniProt
GO_Central
RGD		 PMID:32926445 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:256,513,418...256,554,549
Ensembl chr 1:256,515,562...256,552,814 		JBrowse link
G Wdr4 WD repeat domain 4 involved_in ISO
IBA		 (PMID:15861136)
GO_REF:0000033		 RGD
GO_Central		 PMID:15861136 GO_REF:0000033 NCBI chr20:9,587,205...9,611,434
Ensembl chr20:9,587,207...9,603,581 		JBrowse link
conversion of methionyl-tRNA to N-formyl-methionyl-tRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtfmt mitochondrial methionyl-tRNA formyltransferase involved_in ISO
IBA
IEA
ISS		 (PMID:25288793)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:25288793 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:65,953,787...65,971,841
Ensembl chr 8:65,953,767...65,971,841 		JBrowse link
conversion of seryl-tRNAsec to selenocys-tRNAsec term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740 		JBrowse link
mitochondrial tRNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23042678), (PMID:25925575), (PMID:28888424)		 UniProt
Ensembl
RGD		 PMID:23042678 PMID:25925575 PMID:28888424 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit involved_in ISO (PMID:23042678) RGD PMID:23042678 NCBI chr11:44,584,388...44,589,466
Ensembl chr11:44,584,113...44,589,568 		JBrowse link
G Trmt5 tRNA methyltransferase 5 involved_in ISO
IBA		 (PMID:26189817)
GO_REF:0000033		 RGD
GO_Central		 PMID:26189817 GO_REF:0000033 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
mitochondrial tRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 acts_upstream_of_or_within ISO MGI:5750452 (PMID:25738458) RGD PMID:25738458 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine involved_in ISO (PMID:34774131) RGD PMID:34774131 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676 		JBrowse link
G Trit1 tRNA isopentenyltransferase 1 involved_in ISO (PMID:34774131)
(PMID:24901367)		 RGD PMID:24901367 PMID:34774131 NCBI chr 5:135,293,472...135,341,522
Ensembl chr 5:135,295,330...135,338,764 		JBrowse link
mitochondrial tRNA pseudouridine synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpusd4 RNA pseudouridine synthase D4 involved_in ISO (PMID:28082677) RGD PMID:28082677 NCBI chr 8:33,617,384...33,626,873
Ensembl chr 8:33,617,379...33,626,873 		JBrowse link
mitochondrial tRNA wobble uridine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mto1 mitochondrial tRNA translation optimization 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
SGD:S000003205 (PMID:14522080)		 GO_Central
RGD		 PMID:14522080 GO_REF:0000033 NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231 		JBrowse link
regulation of translational initiation by tRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:27745969)
(MGI:6316585|PMID:27745969)		 RGD PMID:27745969 MGI:6316585 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
regulation of tRNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:15861136)
GO_REF:0000107		 RGD
Ensembl		 PMID:15861136 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
tRNA (guanine-N7)-methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl1 methyltransferase 1, tRNA methylguanosine involved_in ISO (PMID:36599982), (PMID:36599985), (PMID:37369656) RGD PMID:36599982 PMID:36599985 PMID:37369656 NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
G Wdr4 WD repeat domain 4 involved_in ISO (PMID:36599982), (PMID:36599985), (PMID:37369656) RGD PMID:36599982 PMID:36599985 PMID:37369656 NCBI chr20:9,587,205...9,611,434
Ensembl chr20:9,587,207...9,603,581 		JBrowse link
tRNA acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat10 N-acetyltransferase 10 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
tRNA C3-cytosine methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dalrd3 DALR anticodon binding domain containing 3 involved_in ISO
IBA		 (PMID:32427860)
GO_REF:0000033		 RGD
GO_Central		 PMID:32427860 GO_REF:0000033 NCBI chr 8:109,264,100...109,268,560
Ensembl chr 8:109,265,676...109,268,568 		JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine involved_in ISO (PMID:34774131), (PMID:35017528) RGD PMID:34774131 PMID:35017528 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676 		JBrowse link
tRNA C5-cytosine methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun6 NOP2/Sun RNA methyltransferase 6 involved_in ISO (PMID:26160102) RGD PMID:26160102 NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006 		JBrowse link
tRNA dihydrouridine synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dus1l dihydrouridine synthase 1-like involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000117
(PMID:34798057)		 UniProt
RGD		 PMID:34798057 GO_REF:0000024 GO_REF:0000117 NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781 		JBrowse link
G Dus2 dihydrouridine synthase 2 involved_in ISO
IBA		 (PMID:26429968), (PMID:34798057)
GO_REF:0000033		 RGD
GO_Central		 PMID:26429968 PMID:34798057 GO_REF:0000033 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Dus3l dihydrouridine synthase 3-like involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000117
(PMID:34556860), (PMID:34798057)		 UniProt
RGD		 PMID:34556860 PMID:34798057 GO_REF:0000024 GO_REF:0000117 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655 		JBrowse link
G Dus4l dihydrouridine synthase 4-like involved_in ISO (PMID:34798057) RGD PMID:34798057 NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449 		JBrowse link
tRNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh8 alkB homolog 8, tRNA methyltransferase involved_in ISO
IBA		 (PMID:20308323), (PMID:31079898)
GO_REF:0000033
(MGI:4461096|PMID:20123966)		 RGD
GO_Central		 PMID:20123966 PMID:20308323 PMID:31079898 GO_REF:0000033 MGI:4461096 NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165 		JBrowse link
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in ISO
ISS		 (PMID:28119416), (PMID:31919512)
GO_REF:0000024		 RGD
UniProt		 PMID:28119416 PMID:31919512 GO_REF:0000024 NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115 		JBrowse link
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 involved_in ISO
IBA		 UniProtKB:P38238 (PMID:25404562), (PMID:36720500)
GO_REF:0000033		 RGD
GO_Central		 PMID:25404562 PMID:36720500 GO_REF:0000033 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Gtpbp3 GTP binding protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857 		JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084 		JBrowse link
G Mettl1 methyltransferase 1, tRNA methylguanosine involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
G Mettl2 methyltransferase like 2 involved_in ISO MGI:5903740 (PMID:28655767)
(PMID:34268557)		 RGD PMID:28655767 PMID:34268557 NCBI chr10:90,095,527...90,109,354
Ensembl chr10:90,095,527...90,119,528 		JBrowse link
G Mettl6 methyltransferase 6, tRNA N3-cytidine involved_in ISO (PMID:32923617), (PMID:34268557), (PMID:34862464), (PMID:34922197)
MGI:5903741 (PMID:28655767)		 RGD PMID:28655767 PMID:32923617 PMID:34268557 PMID:34862464 PMID:34922197 NCBI chr16:6,683,820...6,699,013
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231 		JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 involved_in ISO
IBA		 (PMID:17071714), (PMID:31287866)
GO_REF:0000033
(MGI:5304206|PMID:22144916), (MGI:6194005|PMID:22885326), (MGI:6368097|PMID:31287866), (MGI:6368099|PMID:23871666), (MGI:6368109|PMID:31276587)		 RGD
GO_Central		 PMID:17071714 PMID:22144916 PMID:22885326 PMID:23871666 PMID:31276587 More... GO_REF:0000033 MGI:5304206 MGI:6194005 MGI:6368097 MGI:6368099 MGI:6368109 NCBI chr 1:33,662,139...33,685,887
Ensembl chr 1:33,662,139...33,685,862 		JBrowse link
G Nsun6 NOP2/Sun RNA methyltransferase 6 involved_in ISO (PMID:28531330) RGD PMID:28531330 NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006 		JBrowse link
G Tarbp1 TAR (HIV-1) RNA binding protein 1 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:54,398,268...54,449,293
Ensembl chr19:54,398,253...54,449,261 		JBrowse link
G Thada THADA, armadillo repeat containing involved_in ISO
IBA		 UniProtKB:Q03496 (PMID:25404562)
GO_REF:0000033		 RGD
GO_Central		 PMID:25404562 GO_REF:0000033 NCBI chr 6:10,183,942...10,488,007
Ensembl chr 6:10,183,982...10,487,159 		JBrowse link
G Thumpd2 THUMP domain containing 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:13,924,742...13,976,657
Ensembl chr 6:13,924,765...13,976,657 		JBrowse link
G Thumpd3 THUMP domain containing 3 involved_in ISO
IBA		 (PMID:34669960)
GO_REF:0000033		 RGD
GO_Central		 PMID:34669960 GO_REF:0000033 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (MGI:6194005|PMID:22885326)
MGI:3695409 (PMID:16424344)
GO_REF:0000024		 RGD
UniProt		 PMID:16424344 PMID:22885326 GO_REF:0000024 MGI:6194005 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439 		JBrowse link
G Trmo tRNA methyltransferase O involved_in ISS
ISO		 GO_REF:0000024
(PMID:25063302)		 UniProt
RGD		 PMID:25063302 GO_REF:0000024 NCBI chr 5:60,663,106...60,676,423
Ensembl chr 5:60,667,864...60,676,423 		JBrowse link
G Trmt10a tRNA methyltransferase 10A involved_in ISO
ISS		 (PMID:25053765)
GO_REF:0000024		 RGD
UniProt		 PMID:25053765 GO_REF:0000024 NCBI chr 2:226,669,445...226,684,166
Ensembl chr 2:226,669,832...226,684,151 		JBrowse link
G Trmt112 tRNA methyltransferase activator subunit 11-2 involved_in ISO (PMID:34669960) RGD PMID:34669960 NCBI chr 1:204,103,298...204,104,151 JBrowse link
G Trmt12 tRNA methyltransferase 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:90,417,846...90,419,472
Ensembl chr 7:90,417,862...90,419,867 		JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843 		JBrowse link
G Trmt44 tRNA methyltransferase 44 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:75,175,331...75,204,291
Ensembl chr14:75,182,029...75,200,147 		JBrowse link
G Trmt61a tRNA methyltransferase 61A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:130,737,230...130,743,251
Ensembl chr 6:130,737,219...130,743,243 		JBrowse link
G Trmt9b tRNA methyltransferase 9B (putative) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:55,740,551...55,792,198
Ensembl chr16:55,743,018...55,792,144 		JBrowse link
G Tyw3 tRNA-yW synthesizing protein 3 homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:243,529,912...243,552,043
Ensembl chr 2:243,529,946...243,552,039 		JBrowse link
G Wdr6 WD repeat domain 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499 		JBrowse link
tRNA methylthiolation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5750452 (MGI:5635958|PMID:25738458)
GO_REF:0000108		 RGD
GOC		 PMID:25738458 GO_REF:0000108 MGI:5635958 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 acts_upstream_of_or_within ISO MGI:5301443 (PMID:21841312) RGD PMID:21841312 NCBI chr17:34,718,701...35,271,276
Ensembl chr17:34,718,687...35,407,524 		JBrowse link
tRNA N1-guanine methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt10a tRNA methyltransferase 10A involved_in ISO
IBA
IEA		 (PMID:32392304)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:32392304 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:226,669,445...226,684,166
Ensembl chr 2:226,669,832...226,684,151 		JBrowse link
G Trmt10b tRNA methyltransferase 10B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:59,548,845...59,572,529
Ensembl chr 5:59,548,869...59,572,526 		JBrowse link
G Trmt5 tRNA methyltransferase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
tRNA N2-guanine methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt1 tRNA methyltransferase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:23,456,756...23,471,581
Ensembl chr19:23,456,756...23,466,956 		JBrowse link
G Trmt1l tRNA methyltransferase 1-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:63,510,097...63,543,268
Ensembl chr13:63,510,204...63,543,266 		JBrowse link
tRNA nucleoside ribose methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 involved_in ISO (PMID:26310293) RGD PMID:26310293 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Thada THADA, armadillo repeat containing involved_in ISO UniProtKB:Q03496 (PMID:35559166) RGD PMID:35559166 NCBI chr 6:10,183,942...10,488,007
Ensembl chr 6:10,183,982...10,487,159 		JBrowse link
tRNA pseudouridine synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pus1 pseudouridine synthase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:15772074)
(PMID:11027153), (PMID:11085940), (PMID:15327771)
GO_REF:0000033
GO_REF:0000117
(MGI:1928672|PMID:10094309), (MGI:5810940|PMID:27197761)		 RGD
GO_Central
UniProt		 PMID:10094309 PMID:11027153 PMID:11085940 PMID:15327771 PMID:15772074 More... GO_REF:0000033 GO_REF:0000117 MGI:1928672 MGI:5810940 NCBI chr12:45,880,364...45,889,196
Ensembl chr12:45,880,440...45,889,196 		JBrowse link
G Pus10 pseudouridine synthase 10 involved_in ISO
IBA		 (PMID:30530625), (PMID:31819270)
GO_REF:0000033		 RGD
GO_Central		 PMID:30530625 PMID:31819270 GO_REF:0000033 NCBI chr14:97,621,228...97,684,059
Ensembl chr14:97,621,391...97,684,046 		JBrowse link
G Pus3 pseudouridine synthase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:27055666)
(PMID:11027153)
GO_REF:0000033		 RGD
GO_Central		 PMID:11027153 PMID:27055666 GO_REF:0000033 NCBI chr 8:33,910,461...33,918,716
Ensembl chr 8:33,911,357...33,918,714 		JBrowse link
G Pus7 pseudouridine synthase 7 involved_in ISO (PMID:29628141), (PMID:34718722) RGD PMID:29628141 PMID:34718722 NCBI chr 4:11,360,169...11,401,139
Ensembl chr 4:11,360,188...11,401,172 		JBrowse link
G Pusl1 pseudouridine synthase like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:166,497,643...166,500,647
Ensembl chr 5:166,496,755...166,500,611 		JBrowse link
tRNA thio-modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctu1 cytosolic thiouridylase subunit 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221 		JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000104		 UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:19017811), (PMID:30817134) RGD PMID:19017811 PMID:30817134 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Urm1 ubiquitin related modifier 1 involved_in ISO (PMID:19017811) RGD PMID:19017811 NCBI chr 3:13,100,340...13,117,064
Ensembl chr 3:13,092,200...13,117,642
Ensembl chr 3:13,092,200...13,117,642 		JBrowse link
tRNA threonylcarbamoyladenosine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gon7 GON7 subunit of KEOPS complex involved_in ISO (PMID:31481669) RGD PMID:31481669 NCBI chr 6:121,882,565...121,898,452
Ensembl chr 6:121,885,694...121,898,643
Ensembl chr 6:121,885,694...121,898,643 		JBrowse link
G Osgep O-sialoglycoprotein endopeptidase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:28805828), (PMID:31481669)		 UniProt
RGD		 PMID:28805828 PMID:31481669 GO_REF:0000024 GO_REF:0000104 NCBI chr15:24,137,149...24,144,568
Ensembl chr15:24,137,153...24,144,568 		JBrowse link
G Osgepl1 O-sialoglycoprotein endopeptidase-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:29760464), (PMID:32047918)		 UniProt
RGD		 PMID:29760464 PMID:32047918 GO_REF:0000024 GO_REF:0000104 NCBI chr 9:48,214,995...48,229,440
Ensembl chr 9:48,215,402...48,229,388 		JBrowse link
G Tprkb Tp53rk binding protein involved_in ISO
IBA
ISS		 (PMID:28805828)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:28805828 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:118,342,910...118,357,908
Ensembl chr 4:118,342,945...118,357,901 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29760464), (PMID:31481669), (PMID:34545459)		 UniProt
Ensembl
RGD		 PMID:29760464 PMID:31481669 PMID:34545459 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120 		JBrowse link
tRNA wobble adenosine to inosine editing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adat2 adenosine deaminase, tRNA-specific 2 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elp1 elongator acetyltransferase complex subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Elp3 elongator acetyltransferase complex subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445 		JBrowse link
tRNA wobble base cytosine methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun3 NOP2/Sun RNA methyltransferase 3 involved_in ISO (PMID:27214402), (PMID:27356879), (PMID:27497299) RGD PMID:27214402 PMID:27356879 PMID:27497299 NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543 		JBrowse link
tRNA wobble cytosine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:27497299) RGD PMID:27497299 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
tRNA wobble position uridine thiolation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctu1 cytosolic thiouridylase subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221 		JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Trmu tRNA mitochondrial 2-thiouridylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:116,969,750...116,987,704
Ensembl chr 7:116,969,756...116,986,355 		JBrowse link
tRNA wobble uridine modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh8 alkB homolog 8, tRNA methyltransferase involved_in ISO
IBA		 (PMID:21285950), (PMID:31079898)
GO_REF:0000033
(MGI:5607402|PMID:20583019)		 RGD
GO_Central		 PMID:20583019 PMID:21285950 PMID:31079898 GO_REF:0000033 MGI:5607402 NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165 		JBrowse link
G Ctu1 cytosolic thiouridylase subunit 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221 		JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000104		 UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 involved_in ISO
IEA		 (MGI:5506828|PMID:23717213)
GO_REF:0000107		 RGD
Ensembl		 PMID:23717213 GO_REF:0000107 MGI:5506828 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:15,885,940...15,921,564
Ensembl chr18:15,885,934...15,921,599 		JBrowse link
G Elp3 elongator acetyltransferase complex subunit 3 involved_in ISO (PMID:29415125) RGD PMID:29415125 NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445 		JBrowse link
G Elp4 elongator acetyltransferase complex subunit 4 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:92,162,271...92,385,251
Ensembl chr 3:92,162,280...92,385,243 		JBrowse link
G Elp4-ps1 elongator acetyltransferase complex subunit 4, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:172,729,315...172,730,773
Ensembl chr 2:172,728,560...172,730,748 		JBrowse link
G Elp5 elongator acetyltransferase complex subunit 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:54,692,526...54,704,255
Ensembl chr10:54,692,530...54,704,923 		JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:110,280,059...110,295,070
Ensembl chr 8:110,279,979...110,295,067 		JBrowse link
G Gtpbp3 GTP binding protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857 		JBrowse link
G Kti12 KTI12 chromatin associated involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:123,601,059...123,602,581
Ensembl chr 5:123,599,436...123,613,964 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:19017811) RGD PMID:19017811 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 acts_upstream_of_or_within ISO SGD:S000003205 (PMID:14522080) RGD PMID:14522080 NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231 		JBrowse link
G Trmt9b tRNA methyltransferase 9B (putative) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:55,740,551...55,792,198
Ensembl chr16:55,743,018...55,792,144 		JBrowse link
G Urm1 ubiquitin related modifier 1 involved_in ISO (PMID:19017811) RGD PMID:19017811 NCBI chr 3:13,100,340...13,117,064
Ensembl chr 3:13,092,200...13,117,642
Ensembl chr 3:13,092,200...13,117,642 		JBrowse link
tRNA-guanine transglycosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Qng1 Q-nucleotide N-glycosylase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:6,281,377...6,288,976
Ensembl chr17:6,281,400...6,288,975 		JBrowse link
G Qtrt1 queuine tRNA-ribosyltransferase catalytic subunit 1 involved_in IEA
IBA
ISO		 GO_REF:0000117
GO_REF:0000033
(MGI:3850292|PMID:19414587), (MGI:7565917|PMID:35815944)
(PMID:20354154), (PMID:34241577)		 UniProt
GO_Central
RGD		 PMID:19414587 PMID:20354154 PMID:34241577 PMID:35815944 GO_REF:0000033 GO_REF:0000117 MGI:3850292 MGI:7565917 NCBI chr 8:19,965,801...19,973,843
Ensembl chr 8:19,966,336...19,973,837 		JBrowse link
G Qtrt2 queuine tRNA-ribosyltransferase accessory subunit 2 involved_in ISO
IBA		 (PMID:20354154), (PMID:34241577)
GO_REF:0000033
(MGI:3850292|PMID:19414587), (MGI:7565917|PMID:35815944)		 RGD
GO_Central		 PMID:19414587 PMID:20354154 PMID:34241577 PMID:35815944 GO_REF:0000033 MGI:3850292 MGI:7565917 NCBI chr11:56,806,417...56,837,239
Ensembl chr11:56,806,385...56,837,228 		JBrowse link
wobble position ribose methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 involved_in ISO (PMID:32558197) RGD PMID:32558197 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Wdr6 WD repeat domain 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:32558197)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:32558197 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499 		JBrowse link
wybutosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcmt2 leucine carboxyl methyltransferase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084 		JBrowse link
G Trmt12 tRNA methyltransferase 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:90,417,846...90,419,472
Ensembl chr 7:90,417,862...90,419,867 		JBrowse link
G Tyw1 tRNA-yW synthesizing protein 1 homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:26,332,020...26,418,286
Ensembl chr12:26,330,351...26,418,208 		JBrowse link
G Tyw3 tRNA-yW synthesizing protein 3 homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:243,529,912...243,552,043
Ensembl chr 2:243,529,946...243,552,039 		JBrowse link
G Tyw5 tRNA-yW synthesizing protein 5 involved_in ISO
IBA		 (PMID:20739293), (PMID:20972222)
GO_REF:0000033		 RGD
GO_Central		 PMID:20739293 PMID:20972222 GO_REF:0000033 NCBI chr 9:58,961,100...58,979,188
Ensembl chr 9:58,961,106...58,979,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      primary metabolic process 10015
        RNA processing 954
          tRNA processing 129
            tRNA modification 89
              archaeosine-tRNA biosynthetic process 0
              charged-tRNA amino acid modification + 2
              cyclic threonylcarbamoyladenosine biosynthetic process 0
              mitochondrial tRNA modification + 8
              regulation of translational initiation by tRNA modification 1
              tRNA acetylation 1
              tRNA adenosine deamination to inosine 0
              tRNA dihydrouridine synthesis 4
              tRNA methylation + 37
              tRNA methylthiolation 2
              tRNA pseudouridine synthesis + 6
              tRNA seleno-modification 0
              tRNA thio-modification + 5
              tRNA threonylcarbamoyladenosine modification + 5
              tRNA wobble base modification + 20
              tRNA-guanine transglycosylation 3
              wybutosine biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular metabolic process 9554
        cellular biosynthetic process 7752
          macromolecule biosynthetic process 7210
            nucleic acid biosynthetic process 4203
              RNA biosynthetic process 4090
                RNA processing 954
                  tRNA processing 129
                    tRNA modification 89
                      archaeosine-tRNA biosynthetic process 0
                      charged-tRNA amino acid modification + 2
                      cyclic threonylcarbamoyladenosine biosynthetic process 0
                      mitochondrial tRNA modification + 8
                      regulation of translational initiation by tRNA modification 1
                      tRNA acetylation 1
                      tRNA adenosine deamination to inosine 0
                      tRNA dihydrouridine synthesis 4
                      tRNA methylation + 37
                      tRNA methylthiolation 2
                      tRNA pseudouridine synthesis + 6
                      tRNA seleno-modification 0
                      tRNA thio-modification + 5
                      tRNA threonylcarbamoyladenosine modification + 5
                      tRNA wobble base modification + 20
                      tRNA-guanine transglycosylation 3
                      wybutosine biosynthetic process 5
paths to the root