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Gene: Tprkb (Tp53rk binding protein) Rattus norvegicus
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Symbol: Tprkb
Name: Tp53rk binding protein
Description: Predicted to have protein kinase binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to localize to the EKC/KEOPS complex; cytosol; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 5. Orthologous to human TPRKB (TP53RK binding protein); INTERACTS WITH cobalt dichloride; flutamide; furan.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cgi-121; EKC/KEOPS complex subunit Tprkb; LOC100910911; LOC297411; Prpk (p53-related protein kinase)-binding protein; RGD1309786; similar to CGI-121 protein; TP53RK-binding protein; TP53RK-binding protein-like
Orthologs:
Homo sapiens (human) : TPRKB (TP53RK binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Tprkb (Tp53rk binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tprkb (TP53RK binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TPRKB (TP53RK binding protein)
Canis lupus familiaris (dog) : TPRKB (TP53RK binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tprkb (TP53RK binding protein)
Sus scrofa (pig) : TPRKB (TP53RK binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04117,589,527 - 117,604,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,345,035 - 182,359,990 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,066,138 - 120,079,624 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14120,315,812 - 120,324,100 (+)NCBI
Celera4107,316,394 - 107,329,878 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tprkb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309786
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.