Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tprkb (Tp53rk binding protein) Rattus norvegicus
Symbol: Tprkb
Name: Tp53rk binding protein
RGD ID: 1309786
Description: Predicted to have protein kinase binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification and telomere maintenance via recombination. Predicted to localize to EKC/KEOPS complex; cytosol; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 5. Orthologous to human TPRKB (TP53RK binding protein); INTERACTS WITH cobalt dichloride; flutamide; furan.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cgi-121; EKC/KEOPS complex subunit Tprkb; LOC100910911; LOC297411; Prpk (p53-related protein kinase)-binding protein; RGD1309786; similar to CGI-121 protein; TP53RK-binding protein; TP53RK-binding protein-like
Homo sapiens (human) : TPRKB (TP53RK binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Tprkb (Tp53rk binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tprkb (TP53RK binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TPRKB (TP53RK binding protein)
Canis lupus familiaris (dog) : TPRKB (TP53RK binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tprkb (TP53RK binding protein)
Sus scrofa (pig) : TPRKB (TP53RK binding protein)
Chlorocebus sabaeus (African green monkey) : TPRKB (TP53RK binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04117,589,527 - 117,604,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,780,533 - 117,785,941 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,589,591 - 117,603,155 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04182,345,035 - 182,359,990 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,066,138 - 120,079,624 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14120,315,812 - 120,324,100 (+)NCBI
Celera4107,316,394 - 107,329,878 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tprkb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309786
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.