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ONTOLOGY REPORT - ANNOTATIONS

Term:endochondral ossification
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Accession:GO:0001958 term browser browse the term
Definition:Replacement ossification wherein bone tissue replaces cartilage.
Synonyms:xref: Wikipedia:Endochondral_ossification


show annotations for term's descendants           Sort by:
endochondral ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated acts_upstream_of_or_within ISO MGI:2183411 (PMID:20684022) RGD PMID:20684022 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20059955)		 UniProt
Ensembl
RGD		 PMID:20059955 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp6 bone morphogenetic protein 6 acts_upstream_of_or_within ISO MGI:2136985 (PMID:9664685) RGD PMID:9664685 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990 (PMID:18539921) RGD PMID:18539921 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570 		JBrowse link
G Cbs cystathionine beta synthase acts_upstream_of_or_within ISO MGI:1857139 (PMID:15622513) RGD PMID:15622513 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Col10a1 collagen type X alpha 1 chain IMP RGD PMID:10853827 RGD:704421 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Col13a1 collagen type XIII alpha 1 chain involved_in ISO (PMID:11470398) RGD PMID:11470398 NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032 		JBrowse link
G Col1a1 collagen type I alpha 1 chain acts_upstream_of_or_within ISO MGI:1856671 (PMID:8130375) RGD PMID:8130375 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10100048)		 Ensembl
RGD		 PMID:10100048 GO_REF:0000107 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within ISO MGI:4947395 (PMID:21148564) RGD PMID:21148564 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Cst5 cystatin D involved_in ISO MGI:3629665 (PMID:16680148) RGD PMID:16680148 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754 		JBrowse link
G Dlx5 distal-less homeobox 5 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:19956613)		 Ensembl
UniProt
RGD		 PMID:19956613 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:6402836 (PMID:24770645) RGD PMID:24770645 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:21185280), (PMID:23958822) RGD PMID:21185280 PMID:23958822 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178751 (PMID:17014841)		 Ensembl
RGD		 PMID:17014841 GO_REF:0000107 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:25808752) RGD PMID:25808752 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 acts_upstream_of_or_within ISO (PMID:25107907) RGD PMID:25107907 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268 		JBrowse link
G Gnas GNAS complex locus involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3043361 (PMID:15797856)		 Ensembl
RGD		 PMID:15797856 GO_REF:0000107 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 acts_upstream_of_or_within ISO MGI:1934892 (PMID:10579729) RGD PMID:10579729 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3665440|MGI:5818514 (PMID:26098911) RGD PMID:26098911 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 involved_in ISO
IEA
ISS		 (PMID:23273569)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23273569 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:99533 (PMID:17336904) RGD PMID:17336904 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mef2d myocyte enhancer factor 2D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99458 (PMID:17336904)		 Ensembl
RGD		 PMID:17336904 GO_REF:0000107 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in IEP
IEA
ISO		 GO_REF:0000107
(PMID:17987127)		 Ensembl
RGD		 PMID:17987127 PMID:10646117 GO_REF:0000107, RGD:10043159 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp14 matrix metallopeptidase 14 acts_upstream_of_or_within ISO MGI:1276107 (PMID:18022611) RGD PMID:18022611 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:101900 (PMID:18022611)		 Ensembl
RGD		 PMID:18022611 GO_REF:0000107 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388 		JBrowse link
G Nab1 Ngfi-A binding protein 1 acts_upstream_of_or_within ISO MGI:107563 (PMID:16136673) RGD PMID:16136673 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098 		JBrowse link
G Nab2 Ngfi-A binding protein 2 acts_upstream_of_or_within ISO MGI:107564 (PMID:16136673) RGD PMID:16136673 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989 		JBrowse link
G Nfix nuclear factor I X involved_in ISO MGI:3714028 (PMID:17353270) RGD PMID:17353270 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IEA
ISO		 GO_REF:0000107
MGI:1856702|MGI:3522129|MGI:3774275 (PMID:15572448), (PMID:15722353), (PMID:17728275)		 Ensembl
RGD		 PMID:15572448 PMID:15722353 PMID:17728275 GO_REF:0000107 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 acts_upstream_of_or_within ISO MGI:3052739 (PMID:12915479) RGD PMID:12915479 NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO MGI:5049904 (PMID:20684022) RGD PMID:20684022 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (PMID:8895385) RGD PMID:8895385 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176466 (PMID:10072783)		 Ensembl
RGD		 PMID:10072783 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (PMID:20059955) RGD PMID:20059955 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sik3 SIK family kinase 3 acts_upstream_of_or_within ISO MGI:5317918 (PMID:22318228) RGD PMID:22318228 NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877|MGI:3575405 (PMID:17591962), (PMID:21788370), (PMID:24505141)		 Ensembl
RGD		 PMID:17591962 PMID:21788370 PMID:24505141 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Tek TEK receptor tyrosine kinase IEP RGD PMID:11735002 RGD:1601509 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (PMID:22416756) RGD PMID:22416756 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    multicellular organismal process 8906
      ossification 524
        replacement ossification 39
          endochondral ossification 39
Path 2
Term Annotations click to browse term
  biological_process 20069
    developmental process 7067
      anatomical structure development 6570
        multicellular organism development 5298
          system development 4583
            skeletal system development 582
              bone development 262
                bone morphogenesis 119
                  endochondral bone morphogenesis 74
                    endochondral ossification 39
paths to the root