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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:coccidiosis
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Accession:DOID:2113 term browser browse the term
Definition:A parasitic protozoa infectious disease that occurs in the intestinal tract of animals and humans caused by Coccidia protozoa. Immunocompromised persons are at greater risk of developing the infection. (DO)
Synonyms:exact_synonym: Besnoitiasis;   Besnoitioses;   Besnoitiosis;   besnoitiases;   coccidioses
 related_synonym: intestinal coccidiosis
 primary_id: MESH:D003048
 xref: EFO:0007212;   NCI:C34493
For additional species annotation, visit the Alliance of Genome Resources.


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coccidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2rb interleukin 2 receptor, beta chain exacerbates IMP RGD PMID:20460838 RGD:42724464 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
Animal Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:blood vessel endothelial cell RGD PMID:15710456 RGD:2307183 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IMP RGD PMID:19741601 RGD:8661685 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Cd209d CD209d antigen treatment IMP RGD PMID:32391004 RGD:39939012 NCBI chr 8:3,921,824...3,928,548
Ensembl chr 8:3,921,824...3,928,555 		JBrowse link
G Foxp3 forkhead box P3 IEP mRNA:decreased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) IEP RGD PMID:8881756 RGD:12910478 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IMP RGD PMID:31231617 RGD:39939039 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Il17a interleukin 17A IEP mRNA,protein:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il21 interleukin 21 IMP RGD PMID:23667536 RGD:127285360 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 IMP RGD PMID:15265921 RGD:39457943 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain ameliorates IMP RGD PMID:11286020 RGD:42724468 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Il6 interleukin 6 IEP mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ldlr low density lipoprotein receptor IMP RGD PMID:18316222 RGD:5490254 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Mir146 microRNA 146 ameliorates IMP RGD PMID:24582962 RGD:126925172 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IMP RGD PMID:25855987 RGD:11057198 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Rorc RAR-related orphan receptor gamma IEP mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 severity IMP RGD PMID:31416833 RGD:39128220 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 severity IMP RGD PMID:20156658 RGD:40902838 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
congenital toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO DNA:polymorphisms: :HLA-DQA1*01:03, HLA-DQA1*03:02 (human) RGD PMID:26856406 RGD:126928144 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
cryptosporidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO DNA:polymorphisms, haplotype:promoter,exon: RGD PMID:19827946 RGD:12910843 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mir21a microRNA 21a IEP RNA:increased expression:ileum RGD PMID:25838265 RGD:40925950 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
Ocular Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IEP RGD PMID:22740770 RGD:7421536 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Il10 interleukin 10 IMP RGD PMID:19026704 RGD:7365028 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il17a interleukin 17A treatment IMP
ISO		 protein:increased expression:aqueous humor (human) RGD PMID:22927448 PMID:22927448 RGD:8698652, RGD:8698652 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il27 interleukin 27 disease_progression IEP mRNA:increased expression:eye, cervical lymph node (mouse) RGD PMID:29779048 RGD:126790500 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:snp:3' utr:g.*397A>C (rs3135499)(human) RGD PMID:23100559 RGD:8547527 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein ISO RGD PMID:24812878 RGD:10054127 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Il27 interleukin 27 susceptibility IMP RGD PMID:31548322 PMID:22981537 RGD:126790501, RGD:126790522 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha exacerbates ISO human gene in a mouse model RGD PMID:12626571 RGD:126925984 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) susceptibility IMP RGD PMID:11101840 RGD:737759 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18302
    disease by infectious agent 2201
      parasitic infectious disease 321
        parasitic protozoa infectious disease 170
          coccidiosis 27
            cryptosporidiosis 2
            cyclosporiasis 0
            cystoisosporiasis 0
            sarcocystosis 0
            toxoplasmosis + 25
paths to the root