Ccr2 (chemokine (C-C motif) receptor 2) - Rat Genome Database

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Gene: Ccr2 (chemokine (C-C motif) receptor 2) Mus musculus
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Symbol: Ccr2
Name: chemokine (C-C motif) receptor 2
RGD ID: 1552061
MGI Page MGI
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including leukocyte migration; regulation of cell migration; and regulation of cytokine production. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Coronavirus infectious disease and age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); glucose metabolism disease (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2); INTERACTS WITH (+)-catechin; (+)-pilocarpine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; CC-CKR-; Cc-ckr-2; CCR; CCR-2; Ccr2a; Ccr2b; chemoattractant protein-1 receptor; chemokine (C-C) receptor 2; CKR; Ckr2; Ckr2a; Ckr2b; Cmkbr; Cmkbr2; JE/FIC receptor; MCP-1 receptor; MIP-1 alphaR; mJe-r
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,901,954 - 123,913,594 (+)NCBIGRCm39mm39
GRCm39 Ensembl9123,901,987 - 123,913,594 (+)Ensembl
GRCm389124,101,918 - 124,109,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,101,950 - 124,113,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv379124,016,922 - 124,023,879 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,950,982 - 123,957,349 (+)NCBImm8
Celera9124,890,502 - 124,897,441 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
age related macular degeneration  (IEA)
aggressive periodontitis  (ISO)
Alcoholic Fatty Liver  (IEP)
allergic bronchopulmonary aspergillosis  (IMP)
allergic contact dermatitis  (IMP,ISO)
allergic disease  (ISO)
Alveolar Bone Loss  (IMP)
amyotrophic lateral sclerosis  (ISO)
Animal Toxoplasmosis  (IMP)
anxiety disorder  (IMP)
asthma  (IEP,ISO)
atopic dermatitis  (ISO)
bacterial pneumonia  (IMP)
Bronchial Hyperreactivity  (IMP)
bronchiolitis obliterans  (IEP)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (IMP)
Chronic Periodontitis  (ISO)
congestive heart failure  (ISO)
corneal neovascularization  (IMP)
coronary artery disease  (ISO)
Coronavirus infectious disease  (IEA)
COVID-19  (ISO)
cutaneous leishmaniasis  (IEP)
demyelinating disease  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (IMP,ISO)
dry eye syndrome  (IMP)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Uveitis  (IMP)
Experimental Autoimmune Uveoretinitis  (IEP)
fungal infectious disease  (ISO)
Geographic Atrophy  (ISO)
Hearing Loss, Noise-Induced  (IMP)
Herpes Simplex Encephalitis  (IMP)
Herpesviridae Infections  (IMP)
human immunodeficiency virus infectious disease  (ISO)
Hyperalgesia  (IMP,ISO)
Hypoxia-Ischemia, Brain  (ISO)
ileitis  (IMP)
inclusion body myositis  (ISO)
intermediate uveitis  (ISO)
interstitial lung disease  (ISO)
Intervertebral Disc Disease  (ISO)
Intimal Hyperplasia  (IMP)
Kawasaki disease  (ISO)
Knee Osteoarthritis  (IMP)
Kuhnt-Junius degeneration  (ISO)
leishmaniasis  (IMP)
limited scleroderma  (IEP)
lipoatrophic diabetes mellitus  (IEP,IMP)
liver disease  (ISO)
Liver Reperfusion Injury  (IMP)
lung disease  (IMP,ISO)
macular degeneration  (ISO)
Mouth Neoplasms  (ISO)
myeloid sarcoma  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
non-alcoholic fatty liver disease  (ISO)
oral squamous cell carcinoma  (ISO)
Pain  (IEP,ISO)
Perennial Allergic Rhinitis  (ISO)
Peri-Implantitis  (ISO)
Periapical Diseases  (IMP)
periapical granuloma  (ISO)
periapical periodontitis  (ISO)
Periodontal Cyst  (ISO)
pleural tuberculosis  (ISO)
pneumonia  (IDA,IMP,ISO)
polymyositis  (ISO)
posterior uveitis  (ISO)
prediabetes syndrome  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary fibrosis  (IMP,ISO)
pulmonary tuberculosis  (IMP)
retinal degeneration  (IMP)
retinitis  (IMP)
rhinitis  (ISO)
sarcoidosis  (ISO)
sciatic neuropathy  (IEP)
sialadenitis  (IDA)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
systemic scleroderma  (IMP)
Thoracic Injuries  (ISO)
Transplant Rejection  (IMP)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urticaria  (ISO)
vasculitis  (IMP)
visceral leishmaniasis  (IEP,IMP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-pilocarpine  (EXP,ISO)
(R)-mevalonic acid  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrobenzenesulfonic acid  (EXP)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-butoxyethanol  (EXP)
3-chlorophenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
9-cis-retinoic acid  (ISO)
acetaldehyde  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
ammonium hexachloroplatinate  (ISO)
amphetamine  (ISO)
amphotericin B  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
asbestos  (ISO)
asperentin  (EXP)
barium sulfate  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzylpenicillin  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bleomycin A2  (EXP)
buta-1,3-diene  (EXP)
carbon nanotube  (EXP)
celecoxib  (EXP)
ceric oxide  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (EXP)
choline  (EXP)
cis-caffeic acid  (EXP)
cisplatin  (ISO)
cocaine  (EXP,ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (EXP)
dextran sulfate  (EXP)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
diethylstilbestrol  (EXP)
disulfiram  (ISO)
doxorubicin  (ISO)
erythromycin A  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
flumequine  (EXP)
folic acid  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
isoniazide  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
linuron  (EXP)
losartan  (ISO)
LY294002  (ISO)
mechlorethamine  (ISO)
MeIQx  (EXP)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
nefazodone  (ISO)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
olaparib  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paricalcitol  (EXP)
PCB138  (ISO)
perindopril  (EXP)
picrotoxin  (ISO)
piperidines  (ISO)
proanthocyanidin  (ISO)
protein kinase inhibitor  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 203580  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium chlorate  (ISO)
sodium fluoride  (ISO)
sterigmatocystin  (EXP)
streptozocin  (EXP)
sulforaphane  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP)
telmisartan  (ISO)
tetrachloromethane  (EXP)
thiram  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (EXP)
trichostatin A  (ISO)
tungsten  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc sulfate  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (TAS)
apoptotic cell clearance  (IC)
blood vessel remodeling  (IEA,ISO)
calcium-mediated signaling  (IBA)
cell chemotaxis  (IBA)
cellular calcium ion homeostasis  (ISO)
cellular defense response  (IMP)
cellular homeostasis  (IDA)
chemokine-mediated signaling pathway  (ISO)
chemotaxis  (IEA)
cytokine-mediated signaling pathway  (ISA,ISO)
G protein-coupled receptor signaling pathway  (IEA,ISO)
hemopoiesis  (IMP)
homeostasis of number of cells within a tissue  (IMP)
humoral immune response  (IMP)
immune response  (IBA,IMP)
inflammatory response  (IBA,IMP,ISO)
inflammatory response to antigenic stimulus  (ISO)
inflammatory response to wounding  (IMP)
leukocyte adhesion to vascular endothelial cell  (IMP)
macrophage migration  (IMP)
monocyte chemotaxis  (IMP)
monocyte extravasation  (IMP)
negative regulation of angiogenesis  (IMP)
negative regulation of eosinophil degranulation  (IMP)
negative regulation of type 2 immune response  (IMP)
neutrophil clearance  (IMP)
positive regulation of alpha-beta T cell proliferation  (IMP)
positive regulation of astrocyte chemotaxis  (ISO)
positive regulation of CD8-positive, alpha-beta T cell extravasation  (IMP)
positive regulation of cold-induced thermogenesis  (IMP)
positive regulation of cytosolic calcium ion concentration  (IBA)
positive regulation of hematopoietic stem cell migration  (IMP)
positive regulation of immune complex clearance by monocytes and macrophages  (IMP)
positive regulation of inflammatory response  (IDA)
positive regulation of interferon-gamma production  (IMP)
positive regulation of interleukin-2 production  (IMP)
positive regulation of leukocyte tethering or rolling  (IMP)
positive regulation of monocyte chemotaxis  (IMP,ISO)
positive regulation of monocyte extravasation  (IMP)
positive regulation of NMDA glutamate receptor activity  (ISO)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of synaptic transmission, glutamatergic  (IMP)
positive regulation of T cell activation  (IMP)
positive regulation of T cell chemotaxis  (IDA)
positive regulation of T-helper 1 cell differentiation  (IC)
positive regulation of T-helper 1 type immune response  (IMP)
positive regulation of thymocyte migration  (IMP)
positive regulation of tumor necrosis factor production  (IMP,ISO)
regulation of cell migration  (IMP)
regulation of inflammatory response  (IMP)
regulation of T cell cytokine production  (IMP)
regulation of T cell differentiation  (IMP)
regulation of vascular endothelial growth factor production  (IMP)
response to hyperoxia  (ISO)
response to hypoxia  (ISO)
sensory perception of pain  (IMP)
signal transduction  (IEA)
T-helper 17 cell chemotaxis  (IDA)
wound healing involved in inflammatory response  (NAS)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone mineral density  (IAGP)
abnormal bone trabecula morphology  (IAGP)
abnormal Bruch membrane morphology  (IAGP)
abnormal cellular extravasation  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal choriocapillaris morphology  (IAGP)
abnormal conditioned taste aversion behavior  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal dendritic cell chemotaxis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal immune serum protein physiology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal interferon level  (IAGP)
abnormal Langerhans cell physiology  (IAGP)
abnormal leukocyte adhesion  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal leukocyte physiology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lymphocyte cell number  (IAGP)
abnormal macrophage chemotaxis  (IAGP)
abnormal macrophage morphology  (IAGP)
abnormal microglial cell physiology  (IAGP)
abnormal monocyte morphology  (IAGP)
abnormal optic choroid morphology  (IAGP)
abnormal osteoclast cell number  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal podocyte morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal retinal pigment epithelium morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
abnormal urine protein level  (IAGP)
abnormal vascular wound healing  (IAGP)
abnormal wound healing  (IAGP)
albuminuria  (IAGP)
alcohol aversion  (IAGP)
alcohol preference  (IAGP)
amyloid beta deposits  (IAGP)
amyloidosis  (IAGP)
bronchiolitis  (IAGP)
choroidal neovascularization  (IAGP)
decreased acute inflammation  (IAGP)
decreased airway responsiveness  (IAGP)
decreased alcohol consumption  (IAGP)
decreased CD11b-high dendritic cell number  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased circulating adiponectin level  (IAGP)
decreased circulating creatinine level  (IAGP)
decreased common myeloid progenitor cell number  (IAGP)
decreased inflammatory response  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-2 secretion  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased macrophage cell number  (IAGP)
decreased monocyte cell number  (IAGP)
decreased neutrophil cell number  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased splenocyte proliferation  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
decreased susceptibility to bone fracture  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to induced colitis  (IAGP)
decreased susceptibility to kidney reperfusion injury  (IAGP)
decreased susceptibility to type I hypersensitivity reaction  (IAGP)
decreased T cell proliferation  (IAGP)
decreased tumor growth/size  (IAGP)
diarrhea  (IAGP)
enlarged heart  (IEA)
enlarged liver  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
expanded mesangial matrix  (IAGP)
glomerulonephritis  (IAGP)
glomerulosclerosis  (IAGP)
hepatic necrosis  (IAGP)
impaired leukocyte tethering or rolling  (IAGP)
impaired macrophage chemotaxis  (IAGP)
increased alcohol consumption  (IAGP)
increased B cell number  (IAGP)
increased CD11b-high dendritic cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating leptin level  (IAGP)
increased dendritic cell number  (IAGP)
increased eosinophil cell number  (IAGP)
increased fluid intake  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased IgG level  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to Coronaviridae infection  (IAGP)
increased susceptibility to Coronaviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to induced colitis  (IAGP)
increased trabecular bone thickness  (IAGP)
increased trabecular bone volume  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
intracranial hemorrhage  (IAGP)
kidney inflammation  (IAGP)
lipofuscinosis  (IAGP)
liver hemorrhage  (IAGP)
liver inflammation  (IAGP)
multifocal hepatic necrosis  (IAGP)
premature death  (IAGP)
renal tubule atrophy  (IAGP)
retinal degeneration  (IAGP)
retinal deposits  (IAGP)
retinal outer nuclear layer degeneration  (IAGP)
retinal photoreceptor degeneration  (IAGP)
weight loss  (IAGP)
References

References - curated
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Genomics

Comparative Map Data
Ccr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,901,954 - 123,913,594 (+)NCBIGRCm39mm39
GRCm39 Ensembl9123,901,987 - 123,913,594 (+)Ensembl
GRCm389124,101,918 - 124,109,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,101,950 - 124,113,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv379124,016,922 - 124,023,879 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,950,982 - 123,957,349 (+)NCBImm8
Celera9124,890,502 - 124,897,441 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
CCR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl346,353,864 - 46,360,940 (+)EnsemblGRCh38hg38GRCh38
GRCh38346,354,111 - 46,360,940 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37346,395,602 - 46,402,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,370,364 - 46,377,432 (+)NCBINCBI36hg18NCBI36
Celera346,332,557 - 46,339,734 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef346,438,874 - 46,446,051 (+)NCBIHuRef
CHM1_1346,345,233 - 46,352,410 (+)NCBICHM1_1
Ccr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28123,734,465 - 123,742,483 (+)NCBI
RGSC_v3.48128,892,784 - 128,893,905 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18128,912,520 - 128,913,642 (+)NCBI
Celera8122,833,545 - 122,834,666 (+)NCBICelera
Cytogenetic Map8q32NCBI
Ccr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542025,641,184 - 25,664,413 (-)NCBIChiLan1.0ChiLan1.0
CCR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1347,361,118 - 47,368,312 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,361,124 - 47,368,312 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0346,255,725 - 46,263,285 (+)NCBIMhudiblu_PPA_v0panPan3
CCR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,305,344 - 42,313,258 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,307,580 - 42,308,698 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,220,658 - 42,229,191 (-)NCBI
ROS_Cfam_1.02042,787,203 - 42,795,751 (-)NCBI
UMICH_Zoey_3.12042,028,417 - 42,036,962 (-)NCBI
UNSW_CanFamBas_1.02042,429,835 - 42,438,385 (-)NCBI
UU_Cfam_GSD_1.02042,710,738 - 42,719,282 (-)NCBI
CCR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,251,959 - 29,376,346 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,368,735 - 29,374,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,532,565 - 32,538,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,795,192 - 7,801,242 (+)NCBI
ChlSab1.1 Ensembl227,798,646 - 7,799,728 (+)Ensembl
Vero_WHO_p1.0NW_023666041159,351,063 - 159,358,108 (-)NCBI

Position Markers
PMC164693P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389124,106,712 - 124,106,794UniSTSGRCm38
MGSCv379124,021,451 - 124,021,533UniSTSGRCm37
Celera9124,892,848 - 124,892,930UniSTS
Cytogenetic Map9FUniSTS
cM Map971.9UniSTS
PMC228408P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389124,105,966 - 124,106,045UniSTSGRCm38
GRCm389124,124,574 - 124,124,653UniSTSGRCm38
MGSCv379124,020,705 - 124,020,784UniSTSGRCm37
MGSCv379124,039,313 - 124,039,392UniSTSGRCm37
Celera9124,893,597 - 124,893,676UniSTS
Celera9124,875,063 - 124,875,142UniSTS
Cytogenetic Map9FUniSTS
cM Map971.9UniSTS
cM Map972.0UniSTS
Cmkbr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389124,106,786 - 124,106,915UniSTSGRCm38
MGSCv379124,021,525 - 124,021,654UniSTSGRCm37
Celera9124,892,727 - 124,892,856UniSTS
Cytogenetic Map9FUniSTS
cM Map972.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1748
Count of miRNA genes:498
Interacting mature miRNAs:566
Transcripts:ENSMUST00000055918, ENSMUST00000165984, ENSMUST00000168841, ENSMUST00000171719
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC168021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U47035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U56819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000055918   ⟹   ENSMUSP00000049909
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9124,102,183 - 124,108,550 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165984   ⟹   ENSMUSP00000128734
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9124,105,626 - 124,109,140 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168841   ⟹   ENSMUSP00000132453
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9124,102,158 - 124,109,507 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171719   ⟹   ENSMUSP00000130112
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9124,101,950 - 124,113,557 (+)Ensembl
RefSeq Acc Id: NM_009915   ⟹   NP_034045
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,902,220 - 123,909,177 (+)NCBI
GRCm389124,102,183 - 124,109,140 (+)NCBI
MGSCv379124,016,922 - 124,023,879 (+)RGD
Celera9124,890,502 - 124,897,441 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512428   ⟹   XP_006512491
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,903,933 - 123,909,177 (+)NCBI
GRCm389124,103,888 - 124,109,140 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243063   ⟹   XP_011241365
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,901,954 - 123,909,177 (+)NCBI
GRCm389124,101,918 - 124,109,140 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243064   ⟹   XP_011241366
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,903,370 - 123,909,177 (+)NCBI
GRCm389124,103,328 - 124,109,140 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036154585   ⟹   XP_036010478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,901,955 - 123,909,177 (+)NCBI
RefSeq Acc Id: XM_036154586   ⟹   XP_036010479
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,901,954 - 123,909,177 (+)NCBI
RefSeq Acc Id: XM_036154587   ⟹   XP_036010480
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399123,901,954 - 123,913,594 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_034045   ⟸   NM_009915
- UniProtKB: P51683 (UniProtKB/Swiss-Prot),   Q3TRK1 (UniProtKB/TrEMBL),   Q543S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512491   ⟸   XM_006512428
- Peptide Label: isoform X1
- UniProtKB: P51683 (UniProtKB/Swiss-Prot),   Q543S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241365   ⟸   XM_011243063
- Peptide Label: isoform X1
- UniProtKB: P51683 (UniProtKB/Swiss-Prot),   Q543S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241366   ⟸   XM_011243064
- Peptide Label: isoform X1
- UniProtKB: P51683 (UniProtKB/Swiss-Prot),   Q543S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000130112   ⟸   ENSMUST00000171719
RefSeq Acc Id: ENSMUSP00000128734   ⟸   ENSMUST00000165984
RefSeq Acc Id: ENSMUSP00000132453   ⟸   ENSMUST00000168841
RefSeq Acc Id: ENSMUSP00000049909   ⟸   ENSMUST00000055918
RefSeq Acc Id: XP_036010480   ⟸   XM_036154587
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036010479   ⟸   XM_036154586
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036010478   ⟸   XM_036154585
- Peptide Label: isoform X1
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:6848386
Promoter ID:MM_ACW:52573
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:CCR2.CSEP07,   CCR2.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369124,018,009 - 124,018,509 (+)MPROMDB
RGD ID:8671368
Promoter ID:EPDNEW_M13715
Type:initiation region
Name:Ccr2_1
Description:Mus musculus chemokine (C-C motif) receptor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13716  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389124,102,152 - 124,102,212EPDNEW
RGD ID:8671370
Promoter ID:EPDNEW_M13716
Type:multiple initiation site
Name:Ccr2_2
Description:Mus musculus chemokine (C-C motif) receptor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13715  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389124,103,618 - 124,103,678EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106185 AgrOrtholog
Ensembl Genes ENSMUSG00000049103 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000049909 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000128734 UniProtKB/Swiss-Prot
  ENSMUSP00000130112 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000132453 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055918 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000165984 UniProtKB/Swiss-Prot
  ENSMUST00000168841 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000171719 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Chemokine_CCR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12772 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:106185 ENTREZGENE
NCBI Gene 12772 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccr2 PhenoGen
PRINTS CCCHEMOKINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHEMOKINER2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CCR2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TRK1 ENTREZGENE, UniProtKB/TrEMBL
  Q3U3U0_MOUSE UniProtKB/TrEMBL
  Q543S8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q61172 UniProtKB/Swiss-Prot