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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:juvenile rheumatoid arthritis
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Accession:DOID:676 term browser browse the term
Definition:A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint. (DO)
Synonyms:exact_synonym: Juvenile Onset Still Disease;   Juvenile Onset Stills Disease;   Juvenile-Onset Still's Disease;   Still's disease;   juvenile arthritis
 narrow_synonym: acute juvenile rheumatoid arthritis;   enthesitis-related juvenile idiopathic arthritis;   extended oligoarticular juvenile idiopathic arthritis;   juvenile chronic arthritis;   juvenile chronic polyarthritis;   juvenile enthesitis-related arthritis;   juvenile idiopathic arthritis;   juvenile oligoarthritis;   juvenile polyarthritis, rheumatoid factor negative;   juvenile polyarthritis, rheumatoid factor positive;   juvenile psoriatic arthritis;   juvenile systemic arthritis;   monarticular juvenile rheumatoid arthritis;   pauciarticular juvenile arthritis;   pauciarticular onset juvenile chronic arthritis;   polyarticular juvenile idiopathic arthritis;   polyarticular juvenile idiopathic arthritis, rheumatoid factor negative;   polyarticular juvenile idiopathic arthritis, rheumatoid factor positive;   psoriasis-related juvenile idiopathic arthritis;   unspecified juvenile idiopathic arthritis
 primary_id: MESH:D001171
 alt_id: OMIM:618795
 xref: EFO:0002609;   EFO:0009730;   EFO:0009731;   EFO:0009732;   EFO:0009733;   EFO:0009734;   EFO:0009746;   EFO:1002007;   EFO:1002020;   GARD:3067;   ICD10CM:M08.4;   ICD9CM:714.3;   ICD9CM:714.31;   ICD9CM:714.32;   ICD9CM:714.33;   NCI:C26979;   NCI:C61279;   ORDO:92
For additional species annotation, visit the Alliance of Genome Resources.


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juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:73,471,837...73,530,778
Ensembl chr13:73,471,889...73,530,011 		JBrowse link
G ACRBP acrosin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:64,036,810...64,047,846
Ensembl chr 5:64,037,095...64,047,847 		JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:34,521,503...34,586,384
Ensembl chr 6:34,519,180...34,585,779 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ANKRD9 ankyrin repeat domain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G AOPEP aminopeptidase O (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:27,078,115...27,472,347
Ensembl chr10:27,078,113...27,472,310 		JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:113,798,380...113,848,452
Ensembl chr 1:113,794,040...113,848,683 		JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:10,103,860...10,451,928
Ensembl chr 4:10,179,758...10,451,929 		JBrowse link
G AVL9 AVL9 cell migration associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:40,663,728...40,739,115
Ensembl chr18:40,663,730...40,739,080 		JBrowse link
G B4GALT5 beta-1,4-galactosyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:51,257,273...51,334,566
Ensembl chr17:51,259,813...51,334,020 		JBrowse link
G BEND2 BEN domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:14,635,795...14,703,934 JBrowse link
G BLTP3B bridge-like lipid transfer protein family member 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:83,935,628...84,041,753
Ensembl chr 5:83,935,703...84,042,202 		JBrowse link
G BTG1 BTG anti-proliferation factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:90,815,194...90,817,936
Ensembl chr 5:90,815,202...90,817,142 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:182,209,850...182,228,626
Ensembl chr13:182,208,958...182,227,971 		JBrowse link
G C15H2orf88 chromosome 15 C2orf88 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:94,628,283...94,794,114
Ensembl chr15:94,478,021...94,791,775 		JBrowse link
G C8B complement C8 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 6:155,411,982...155,453,034
Ensembl chr 6:155,387,145...155,453,438 		JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:38,389,366...38,415,903
Ensembl chr10:38,389,331...38,415,901 		JBrowse link
G CALD1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G CCDC122 coiled-coil domain containing 122 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS ClinVar PMID:25741868 NCBI chr11:23,159,655...23,199,074
Ensembl chr11:23,159,470...23,198,885 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
DNA:polymorphisms: :multiple (human)		 RGD PMID:16775617 PMID:17565662 RGD:1626283 RGD:1626284 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CD14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G CD83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:10,346,122...10,385,968
Ensembl chr 7:10,359,211...10,385,961 		JBrowse link
G CD8B CD8 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:57,968,358...57,986,450
Ensembl chr 3:57,968,383...57,986,441 		JBrowse link
G CIITA class II major histocompatibility complex transactivator no_association
susceptibility		 ISO DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:polymorphism:exon:1614G>C (human)		 RGD PMID:16426246 PMID:17661914 RGD:5491187 RGD:5491189 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780 		JBrowse link
G CLU clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G CMTM2 CKLF like MARVEL transmembrane domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:27,281,809...27,295,429
Ensembl chr 6:27,282,070...27,295,522 		JBrowse link
G CREM cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:57,829,523...57,895,610
Ensembl chr10:57,829,518...57,895,610 		JBrowse link
G CRP C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103 		JBrowse link
G CTTN cortactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 PMID:26387944 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086 		JBrowse link
G DUSP2 dual specificity phosphatase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:47,052,443...47,054,816
Ensembl chr 3:47,052,458...47,054,810 		JBrowse link
G DUSP4 dual specificity phosphatase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:55,491,084...55,508,460
Ensembl chr15:55,491,087...55,508,455 		JBrowse link
G DYSF dysferlin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:71,020,143...71,237,658
Ensembl chr 3:71,020,144...71,246,967 		JBrowse link
G EGF epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046 		JBrowse link
G EGR1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G ELF2 E74 like ETS transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:87,774,594...87,878,847
Ensembl chr 8:87,854,699...87,878,662 		JBrowse link
G ETNK1 ethanolamine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:50,914,808...50,970,748
Ensembl chr 5:50,914,814...50,970,697 		JBrowse link
G ETV6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:60,523,530...60,776,792
Ensembl chr 5:60,523,433...60,776,750 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:11,606,469...11,663,086
Ensembl chr12:11,607,034...11,657,737 		JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:68,359,243...68,389,968
Ensembl chr16:68,359,307...68,389,965 		JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,523...7,608,469 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:51,836,780...51,844,531
Ensembl chr 6:51,837,719...51,844,529 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:110,820,403...110,842,903
Ensembl chr 3:110,823,666...110,843,068 		JBrowse link
G FOXP1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:144,940,702...144,944,089
Ensembl chr 6:144,940,697...144,944,089 		JBrowse link
G GMPR guanosine monophosphate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:12,254,393...12,298,802
Ensembl chr 7:12,254,388...12,299,531 		JBrowse link
G GNG11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:73,721,327...73,726,229
Ensembl chr 9:73,721,322...73,726,222 		JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:51,261,097...51,261,903
Ensembl chr14:51,260,963...51,262,114 		JBrowse link
G H2AC4 H2A clustered histone 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:20,729,940...20,730,466
Ensembl chr 7:20,729,997...20,730,389 		JBrowse link
G HBEGF heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:142,102,455...142,115,192
Ensembl chr 2:142,102,458...142,115,174 		JBrowse link
G HERPUD2 HERPUD family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:38,284,520...38,326,323
Ensembl chr18:38,284,520...38,326,311 		JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:88,970,592...88,973,109
Ensembl chr 4:88,970,599...88,973,918 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G IL1A interleukin 1 alpha ISO DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504
G IL2 interleukin 2 ISO protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G ITGA2B integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:18,860,739...18,877,381
Ensembl chr12:18,860,739...18,877,381 		JBrowse link
G ITGB5 integrin subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:135,468,111...135,587,483
Ensembl chr13:135,467,798...135,587,473 		JBrowse link
G JMJD1C jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:66,640,845...66,966,911
Ensembl chr14:66,640,849...66,920,324 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G KAT6B lysine acetyltransferase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:77,390,790...77,597,674
Ensembl chr14:77,404,136...77,597,673 		JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:201,894,036...201,941,449
Ensembl chr13:201,894,420...201,939,789 		JBrowse link
G KLF4 KLF transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:248,604,817...248,609,574
Ensembl chr 1:248,604,820...248,609,035 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358 		JBrowse link
G LACC1 laccase domain containing 1 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS OMIM
ClinVar		 PMID:25147203 PMID:25220867 PMID:25741868 PMID:27881174 PMID:29717096 More... NCBI chr11:23,143,708...23,159,790
Ensembl chr11:23,141,133...23,159,649 		JBrowse link
G LOC102160336 ubiquitin-conjugating enzyme E2 E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:10,605,837...10,683,819
Ensembl chr13:10,605,503...10,683,816 		JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:125,782,373...126,478,927
Ensembl chr13:125,782,471...126,463,303 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041 		JBrowse link
G MAFF MAF bZIP transcription factor F ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:9,683,651...9,696,128
Ensembl chr 5:9,683,660...9,696,023 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:27,993,319...28,372,982
Ensembl chr 9:27,997,887...28,371,397 		JBrowse link
G MAP2 microtubule associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:112,156,578...112,462,932
Ensembl chr15:112,236,119...112,462,929 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:18334024 RGD:12910845 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083 		JBrowse link
G MEX3C mex-3 RNA binding family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:100,678,452...100,699,277
Ensembl chr 1:100,676,660...100,699,403 		JBrowse link
G MS4A4A membrane spanning 4-domains A4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:11,226,146...11,368,033 JBrowse link
G MSN moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:51,844,197...51,967,674
Ensembl chr  X:51,844,156...51,970,107 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:14,933,290...15,103,256
Ensembl chr 4:14,933,331...15,103,253 		JBrowse link
G MYZAP myocardial zonula adherens protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:114,287,622...114,386,418
Ensembl chr 1:114,287,627...114,386,427 		JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:53,553,897...53,640,470
Ensembl chr12:53,557,175...53,640,457 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:63,487,051...63,506,249
Ensembl chr15:63,487,731...63,495,299 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,570,010...241,611,727 		JBrowse link
G NRG1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:61,799,356...61,809,691
Ensembl chr 5:61,799,286...61,810,624 		JBrowse link
G OSM oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:47,242,767...47,246,836
Ensembl chr14:47,242,774...47,246,838 		JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:5,853,377...5,985,174
Ensembl chr 5:5,853,377...5,985,169 		JBrowse link
G PCYT1B phosphate cytidylyltransferase 1B, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:20,605,769...20,743,081
Ensembl chr  X:20,605,945...20,743,134 		JBrowse link
G PER1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:53,361,863...53,376,723
Ensembl chr12:53,361,889...53,374,248 		JBrowse link
G PGM5 phosphoglucomutase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:221,634,516...221,837,764
Ensembl chr 1:221,634,524...221,836,459 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
G PLK2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:37,299,116...37,305,114
Ensembl chr16:37,299,119...37,305,114 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:86,402,673...86,513,167
Ensembl chr13:86,401,244...86,513,105 		JBrowse link
G PROS1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:165,915,298...165,999,118
Ensembl chr13:165,911,366...165,999,811 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G R3HDM2 R3H domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:22,558,645...22,714,250
Ensembl chr 5:22,549,010...22,719,054 		JBrowse link
G RASGEF1B RasGEF domain family member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:135,896,022...136,595,051
Ensembl chr 8:136,568,711...136,595,049 		JBrowse link
G RBM47 RNA binding motif protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:31,508,133...31,690,757
Ensembl chr 8:31,508,148...31,690,409 		JBrowse link
G RERE arginine-glutamic acid dipeptide repeats ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:68,954,766...69,258,855 JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:64,326,461...64,465,331
Ensembl chr14:64,326,461...64,465,281 		JBrowse link
G RNF103 ring finger protein 103 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:58,161,087...58,183,750
Ensembl chr 3:58,161,261...58,186,858 		JBrowse link
G SELP selectin P severity ISO protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G SH2D2A SH2 domain containing 2A ISO DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chr 4:93,282,383...93,293,214
Ensembl chr 4:93,282,413...93,293,205 		JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:86,416,281...86,481,805
Ensembl chr 1:86,358,483...86,481,776 		JBrowse link
G SIK1 salt inducible kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:206,454,695...206,465,802
Ensembl chr13:206,454,718...206,465,807 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:94,789,794...95,168,728
Ensembl chr 7:95,022,924...95,167,107 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10857800 PMID:16597321 RGD:5684977 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC22A16 solute carrier family 22 member 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:76,423,386...76,468,267
Ensembl chr 1:76,423,355...76,467,575 		JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility ISO DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr 2:150,996,868...151,027,483
Ensembl chr 2:150,996,686...151,022,148 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:62,963,635...63,041,955 JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G STAB1 stabilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:34,630,448...34,659,371
Ensembl chr13:34,636,083...34,659,219 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G STIM1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575 		JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417 		JBrowse link
G TFDP1 transcription factor Dp-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:78,755,472...78,778,312
Ensembl chr11:78,755,533...78,778,309 		JBrowse link
G TFPI tissue factor pathway inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:92,345,083...92,409,962
Ensembl chr15:92,345,075...92,409,905 		JBrowse link
G THBD thrombomodulin ISO protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,217,303...30,224,099 		JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:862,013...881,352
Ensembl chr15:862,015...881,461 		JBrowse link
G TNFAIP8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:123,152,349...123,285,154
Ensembl chr 2:123,152,371...123,287,941 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:109,642,848...110,052,345
Ensembl chr13:109,643,895...110,052,236 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:36,455,628...36,460,711
Ensembl chr 7:36,455,634...36,460,715 		JBrowse link
G TTLL5 tubulin tyrosine ligase like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:98,822,338...99,090,076
Ensembl chr 7:98,823,871...99,130,915 		JBrowse link
G UBE3C ubiquitin protein ligase E3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:1,542,454...1,654,274
Ensembl chr18:1,542,163...1,653,982 		JBrowse link
G WASF3 WASP family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,253 		JBrowse link
G WWOX WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053 		JBrowse link
G ZFAND3 zinc finger AN1-type containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:33,378,229...33,718,034
Ensembl chr 7:33,378,286...33,718,030 		JBrowse link
G ZFC3H1 zinc finger C3H1-type containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:35,617,257...35,671,191
Ensembl chr 5:35,617,266...35,671,149 		JBrowse link
Systemic Juvenile Rheumatoid Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:26914138 RGD:11529541 NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,473 		JBrowse link
G IL6 interleukin 6 ISO OMIM NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IL6R interleukin 6 receptor treatment ISO RGD PMID:18358927 RGD:10402823 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,433...95,381,282 		JBrowse link
G MIF macrophage migration inhibitory factor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15274
    disease of anatomical entity 14908
      musculoskeletal system disease 7701
        connective tissue disease 5253
          rheumatic disease 683
            rheumatoid arthritis 427
              juvenile rheumatoid arthritis 142
                Familial Granulomatous Arteritis with Juvenile Polyarthritis 0
                Juvenile Pauciarticular Chronic Arthritis 0
                Systemic Juvenile Rheumatoid Arthritis 4
Path 2
Term Annotations click to browse term
  disease 15274
    disease of anatomical entity 14908
      Skin and Connective Tissue Diseases 6749
        connective tissue disease 5253
          bone disease 3815
            bone inflammation disease 1276
              arthropathy 1258
                arthritis 843
                  rheumatoid arthritis 427
                    juvenile rheumatoid arthritis 142
                      Familial Granulomatous Arteritis with Juvenile Polyarthritis 0
                      Juvenile Pauciarticular Chronic Arthritis 0
                      Systemic Juvenile Rheumatoid Arthritis 4
paths to the root