DUSP2 (dual specificity phosphatase 2) - Rat Genome Database

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Gene: DUSP2 (dual specificity phosphatase 2) Sus scrofa
Analyze
Symbol: DUSP2
Name: dual specificity phosphatase 2
RGD ID: 14138140
Description: ENCODES a protein that exhibits hydrolase activity (inferred); MAP kinase tyrosine/serine/threonine phosphatase activity (inferred); mitogen-activated protein kinase binding (inferred); INVOLVED IN protein dephosphorylation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); intellectual disability (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear membrane (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dual specificity protein phosphatase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,052,457 - 47,054,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,052,443 - 47,054,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,187,416 - 49,194,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
DUSP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,052,457 - 47,054,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,052,443 - 47,054,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,187,416 - 49,194,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl296,143,169 - 96,145,440 (-)EnsemblGRCh38hg38GRCh38
GRCh38296,143,166 - 96,145,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37296,808,908 - 96,811,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,172,638 - 96,174,906 (-)NCBINCBI36hg18NCBI36
Build 34296,230,790 - 96,233,053NCBI
Celera291,249,715 - 91,251,986 (-)NCBI
Cytogenetic Map2q11.2NCBI
HuRef290,770,185 - 90,772,456 (-)NCBIHuRef
CHM1_1296,813,182 - 96,815,453 (-)NCBICHM1_1
Dusp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,178,079 - 127,180,297 (+)NCBIGRCm39mm39
GRCm39 Ensembl2127,178,079 - 127,180,296 (+)Ensembl
GRCm382127,336,159 - 127,338,377 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,336,159 - 127,338,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,161,895 - 127,164,113 (+)NCBIGRCm37mm9NCBIm37
MGSCv362127,027,600 - 127,029,818 (+)NCBImm8
MGSCv362128,316,151 - 128,318,369 (+)NCBImm8
Cytogenetic Map2F1NCBI
Dusp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23114,556,325 - 114,558,510 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)Ensembl
Rnor_6.03119,776,925 - 119,779,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,303,199 - 126,305,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,838,605 - 114,840,790 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13114,744,177 - 114,746,352 (+)NCBI
Celera3113,395,499 - 113,397,684 (+)NCBICelera
Cytogenetic Map3q36NCBI
Dusp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,735,871 - 3,737,568 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,735,224 - 3,737,667 (-)NCBIChiLan1.0ChiLan1.0
DUSP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A97,068,210 - 97,070,505 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v02A103,169,874 - 103,172,158 (+)NCBIMhudiblu_PPA_v0panPan3
DUSP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,586,635 - 34,589,076 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,586,716 - 34,588,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,356,392 - 34,358,603 (+)NCBI
ROS_Cfam_1.01735,357,957 - 35,360,188 (+)NCBI
ROS_Cfam_1.0 Ensembl1735,357,957 - 35,360,187 (+)Ensembl
UMICH_Zoey_3.11734,487,278 - 34,489,485 (+)NCBI
UNSW_CanFamBas_1.01734,555,607 - 34,557,809 (+)NCBI
UU_Cfam_GSD_1.01734,762,735 - 34,764,961 (+)NCBI
Dusp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,018,673 - 83,020,329 (-)NCBI
SpeTri2.0NW_004936744271,619 - 273,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114580,686 - 582,939 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl14580,694 - 582,910 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041168,001,720 - 168,004,581 (-)NCBIVero_WHO_p1.0
Dusp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247492,258,317 - 2,260,542 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 6 2 3 5 3 2 3
Below cutoff 3 2 4 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000047370   ⟹   ENSSSCP00000032791
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl347,052,457 - 47,054,816 (+)Ensembl
RefSeq Acc Id: XM_021087101   ⟹   XP_020942760
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1347,052,443 - 47,054,816 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020942760 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020942760   ⟸   XM_021087101
- Sequence:
RefSeq Acc Id: ENSSSCP00000032791   ⟸   ENSSSCT00000047370

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035971 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070027517 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000032791 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070046813 UniProtKB/TrEMBL
  ENSSSCP00070046814 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000047370 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070055164 UniProtKB/TrEMBL
  ENSSSCT00070055165 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  MKP UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Rhodanese-like_dom UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/TrEMBL
NCBI Gene DUSP2 ENTREZGENE
Pfam DSPc UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
PIRSF MAPK_Ptase UniProtKB/TrEMBL
PRINTS MAPKPHPHTASE UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
SMART DSPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  RHOD UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
  SSF52821 UniProtKB/TrEMBL
UniProt A0A286ZMV8_PIG UniProtKB/TrEMBL
  A0A4X1VT29_PIG UniProtKB/TrEMBL
  A0A4X1VXN2_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87481 ENTREZGENE