WASF3 (WASP family member 3) - Rat Genome Database

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Gene: WASF3 (WASP family member 3) Sus scrofa
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Symbol: WASF3
Name: WASP family member 3
RGD ID: 14002148
Description: ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN cytoskeleton organization (ortholog); lamellipodium assembly (ortholog); oligodendrocyte development (ortholog); ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN glutamatergic synapse (ortholog); lamellipodium (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: WAS protein family member 3; wiskott-Aldrich syndrome protein family member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,261,177 - 4,366,254 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,736,220 - 3,791,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
glutamatergic synapse  (IEA,ISO)
lamellipodium  (IBA,ISO)
postsynapse  (IEA,ISO)
SCAR complex  (IBA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
WASF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,261,177 - 4,366,254 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,736,220 - 3,791,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WASF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1326,557,683 - 26,688,948 (+)EnsemblGRCh38hg38GRCh38
GRCh381326,539,139 - 26,688,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371327,131,820 - 27,263,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361326,029,840 - 26,161,082 (+)NCBINCBI36hg18NCBI36
Build 341326,029,886 - 26,161,063NCBI
Celera138,256,077 - 8,332,052 (+)NCBI
Cytogenetic Map13q12.13NCBI
HuRef137,955,351 - 8,086,464 (+)NCBIHuRef
CHM1_11327,099,816 - 27,231,081 (+)NCBICHM1_1
Wasf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395146,321,816 - 146,410,425 (+)NCBIGRCm39mm39
GRCm39 Ensembl5146,321,795 - 146,410,425 (+)Ensembl
GRCm385146,385,006 - 146,473,615 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5146,384,985 - 146,473,615 (+)EnsemblGRCm38mm10GRCm38
MGSCv375147,196,582 - 147,282,701 (+)NCBIGRCm37mm9NCBIm37
MGSCv365146,689,240 - 146,774,650 (+)NCBImm8
Celera5144,372,570 - 144,458,483 (+)NCBICelera
Cytogenetic Map5G3NCBI
Wasf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2128,563,805 - 8,660,799 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl128,562,062 - 8,660,751 (-)Ensembl
Rnor_6.01210,297,896 - 10,391,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1210,298,555 - 10,391,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01212,401,989 - 12,493,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1210,379,274 - 10,474,931 (-)NCBICelera
Cytogenetic Map12p11NCBI
Wasf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554976,102,909 - 6,190,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554976,100,633 - 6,190,639 (+)NCBIChiLan1.0ChiLan1.0
WASF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11326,250,171 - 26,328,553 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1326,250,171 - 26,328,553 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0137,849,687 - 7,980,979 (+)NCBIMhudiblu_PPA_v0panPan3
WASF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12512,804,485 - 12,881,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2512,805,431 - 12,877,770 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2512,875,143 - 13,008,318 (-)NCBI
ROS_Cfam_1.02512,944,371 - 13,077,673 (-)NCBI
UMICH_Zoey_3.12512,830,485 - 12,963,635 (-)NCBI
UNSW_CanFamBas_1.02512,822,254 - 12,955,911 (-)NCBI
UU_Cfam_GSD_1.02512,873,760 - 13,006,959 (-)NCBI
Wasf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945115,180,691 - 115,300,651 (+)NCBI
SpeTri2.0NW_004936948345,942 - 465,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.135,805,115 - 5,934,764 (+)NCBI
ChlSab1.1 Ensembl35,889,263 - 5,931,662 (+)Ensembl
Vero_WHO_p1.0NW_02366605738,489,195 - 38,621,738 (-)NCBI
Wasf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 13
Low 9 4 2 5 2 10 2 3 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010188   ⟹   ENSSSCP00000009922
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl114,261,177 - 4,366,254 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000085283   ⟹   ENSSSCP00000067667
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl114,261,177 - 4,366,254 (+)Ensembl
RefSeq Acc Id: XM_021065503   ⟹   XP_020921162
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,284,561 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065504   ⟹   XP_020921163
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,136 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065505   ⟹   XP_020921164
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,136 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065506   ⟹   XP_020921165
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,299,212 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065507   ⟹   XP_020921166
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,148 - 4,366,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065508   ⟹   XP_020921167
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,284,561 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065509   ⟹   XP_020921168
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,130 - 4,363,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065510   ⟹   XP_020921169
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,148 - 4,366,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065511   ⟹   XP_020921170
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020921170   ⟸   XM_021065511
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020921168   ⟸   XM_021065509
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921163   ⟸   XM_021065504
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921164   ⟸   XM_021065505
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921166   ⟸   XM_021065507
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921169   ⟸   XM_021065510
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020921162   ⟸   XM_021065503
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921167   ⟸   XM_021065508
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020921165   ⟸   XM_021065506
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000009922   ⟸   ENSSSCT00000010188
RefSeq Acc Id: ENSSSCP00000067667   ⟸   ENSSSCT00000085283
Protein Domains
WH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009300 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000009922 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067667 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010188 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000085283 ENTREZGENE, UniProtKB/TrEMBL
InterPro SCAR/WAVE_fam UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
NCBI Gene WASF3 ENTREZGENE
PANTHER PTHR12902 UniProtKB/TrEMBL
Pfam WH2 UniProtKB/TrEMBL
PROSITE WH2 UniProtKB/TrEMBL
SMART WH2 UniProtKB/TrEMBL
UniProt A0A480KT11_PIG UniProtKB/TrEMBL
  F1RTK2_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94894 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 WASF3  WASP family member 3    WAS protein family member 3  Symbol and/or name change 5135510 APPROVED