MAD1L1 (mitotic arrest deficient 1 like 1) - Rat Genome Database

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Gene: MAD1L1 (mitotic arrest deficient 1 like 1) Sus scrofa
Analyze
Symbol: MAD1L1
Name: mitotic arrest deficient 1 like 1
RGD ID: 14236581
Description: ENCODES a protein that exhibits identical protein binding (inferred); kinetochore binding (inferred); INVOLVED IN cytoplasmic sequestering of protein (ortholog); deactivation of mitotic spindle assembly checkpoint (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Familial Prostate Cancer (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN cytoplasm (inferred); kinetochore (inferred); MAD1 complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MAD1 mitotic arrest deficient like 1; mitotic spindle assembly checkpoint protein MAD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,236,076 - 1,559,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,236,066 - 1,559,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.231,859,406 - 1,883,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MAD1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,236,076 - 1,559,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,236,066 - 1,559,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.231,859,406 - 1,883,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAD1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3871,815,795 - 2,232,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl71,815,793 - 2,233,243 (-)EnsemblGRCh38hg38GRCh38
GRCh3771,855,431 - 2,272,580 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3671,821,954 - 2,239,109 (-)NCBINCBI36Build 36hg18NCBI36
Build 3471,628,673 - 2,043,593NCBI
Celera71,824,029 - 2,242,272 (-)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef71,775,090 - 2,191,874 (-)NCBIHuRef
CHM1_171,855,013 - 2,272,150 (-)NCBICHM1_1
T2T-CHM13v2.071,928,871 - 2,346,389 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v271,908,333 - 2,321,257 (-)NCBI
Mad1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395139,994,444 - 140,307,346 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5139,994,444 - 140,307,307 (-)EnsemblGRCm39 Ensembl
GRCm385140,008,689 - 140,321,608 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,008,689 - 140,321,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv375140,484,643 - 140,797,506 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365140,261,163 - 140,574,024 (-)NCBIMGSCv36mm8
Celera5137,065,976 - 137,380,304 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map578.82NCBI
Mad1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,434,782 - 19,744,574 (+)NCBIGRCr8
mRatBN7.21214,320,892 - 14,630,750 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,320,892 - 14,630,703 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,128,699 - 15,439,478 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,752,197 - 16,062,988 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,778,908 - 15,089,705 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,410,083 - 16,721,232 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,410,083 - 16,719,824 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,402,692 - 18,711,591 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,793,899 - 15,107,476 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1216,079,638 - 16,388,296 (+)NCBICelera
Cytogenetic Map12q11NCBI
Mad1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554609,340,681 - 9,672,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554609,340,728 - 9,672,478 (-)NCBIChiLan1.0ChiLan1.0
MAD1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v266,773,465 - 7,199,146 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1755,098,168 - 55,523,724 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v072,070,299 - 2,502,471 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.172,187,104 - 2,604,168 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl72,187,104 - 2,601,328 (-)Ensemblpanpan1.1panPan2
MAD1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,889,126 - 15,236,194 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,882,875 - 15,236,192 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha616,351,128 - 16,704,460 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0615,015,423 - 15,362,579 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl615,014,693 - 15,362,577 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,818,674 - 15,165,656 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,745,470 - 15,092,432 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0615,033,169 - 15,380,211 (+)NCBIUU_Cfam_GSD_1.0
Mad1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344143,053,218 - 143,167,762 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367541,842,588 - 1,957,116 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAD1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12819,358,942 - 19,768,079 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2819,359,233 - 19,768,078 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660901,956,015 - 2,370,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mad1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474027,174,354 - 27,523,492 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474027,174,450 - 27,523,366 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MAD1L1
12250 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000043497   ⟹   ENSSSCP00000058115
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,239,201 - 1,559,041 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000062437   ⟹   ENSSSCP00000037716
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,236,078 - 1,559,032 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000065594   ⟹   ENSSSCP00000038605
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,236,076 - 1,556,751 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000088241   ⟹   ENSSSCP00000072540
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl31,300,282 - 1,559,040 (-)Ensembl
RefSeq Acc Id: XM_021085975   ⟹   XP_020941634
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.131,236,066 - 1,559,346 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020941634 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000037716
  ENSSSCP00000037716.3
  ENSSSCP00000038605.1
  ENSSSCP00000058115.2
  ENSSSCP00060010103.1
  ENSSSCP00070015891.1
  ENSSSCP00070015897.1
RefSeq Acc Id: XP_020941634   ⟸   XM_021085975
- UniProtKB: A0A480SZZ0 (UniProtKB/TrEMBL),   A0A4X1TLE7 (UniProtKB/TrEMBL),   A0A8D1T919 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000072540   ⟸   ENSSSCT00000088241
Ensembl Acc Id: ENSSSCP00000038605   ⟸   ENSSSCT00000065594
Ensembl Acc Id: ENSSSCP00000037716   ⟸   ENSSSCT00000062437
Ensembl Acc Id: ENSSSCP00000058115   ⟸   ENSSSCT00000043497


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038766 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00060017967 UniProtKB/TrEMBL
  ENSSSCG00070009845 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000043497.3 UniProtKB/TrEMBL
  ENSSSCT00000062437 ENTREZGENE
  ENSSSCT00000062437.3 UniProtKB/TrEMBL
  ENSSSCT00000065594.3 UniProtKB/TrEMBL
  ENSSSCT00060024088.1 UniProtKB/TrEMBL
  ENSSSCT00070019121.1 UniProtKB/TrEMBL
  ENSSSCT00070019127.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  3.30.457.60 UniProtKB/TrEMBL
  6.10.250.90 UniProtKB/TrEMBL
InterPro Mad1 UniProtKB/TrEMBL
NCBI Gene MAD1L1 ENTREZGENE
PANTHER MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 UniProtKB/TrEMBL
  PTHR23168 UniProtKB/TrEMBL
Pfam MAD UniProtKB/TrEMBL
Superfamily-SCOP Mitotic arrest deficient-like 1, Mad1 UniProtKB/TrEMBL
UniProt A0A287A1B8_PIG UniProtKB/TrEMBL
  A0A287A3Z0_PIG UniProtKB/TrEMBL
  A0A287BNC2_PIG UniProtKB/TrEMBL
  A0A480SZZ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TL49_PIG UniProtKB/TrEMBL
  A0A4X1TLE7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1T919 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89938 ENTREZGENE