TNFAIP8 (TNF alpha induced protein 8) - Rat Genome Database

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Gene: TNFAIP8 (TNF alpha induced protein 8) Sus scrofa
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Symbol: TNFAIP8
Name: TNF alpha induced protein 8
RGD ID: 13845486
Description: ENCODES a protein that exhibits molecular sequestering activity (ortholog); small molecule binding (ortholog); INVOLVED IN defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: tumor necrosis factor alpha-induced protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2123,152,371 - 123,287,941 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12123,152,349 - 123,285,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22128,681,402 - 128,723,913 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:16504160   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TNFAIP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2123,152,371 - 123,287,941 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12123,152,349 - 123,285,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22128,681,402 - 128,723,913 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFAIP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385119,268,759 - 119,399,688 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5119,268,692 - 119,399,688 (+)EnsemblGRCh38hg38GRCh38
GRCh375118,604,454 - 118,735,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365118,632,317 - 118,758,193 (+)NCBINCBI36Build 36hg18NCBI36
Build 345118,719,628 - 118,758,192NCBI
Celera5114,558,091 - 114,683,993 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5113,799,532 - 113,925,583 (+)NCBIHuRef
CHM1_15118,037,375 - 118,163,249 (+)NCBICHM1_1
T2T-CHM13v2.05119,789,607 - 119,920,525 (+)NCBIT2T-CHM13v2.0
Tnfaip8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391850,112,494 - 50,226,296 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1850,112,494 - 50,240,240 (+)EnsemblGRCm39 Ensembl
GRCm381849,979,427 - 50,093,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1849,979,427 - 50,107,173 (+)EnsemblGRCm38mm10GRCm38
MGSCv371850,139,081 - 50,252,883 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361850,178,850 - 50,217,109 (+)NCBIMGSCv36mm8
Celera1851,306,422 - 51,422,906 (+)NCBICelera
Cytogenetic Map18D1NCBI
cM Map1827.18NCBI
Tnfaip8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81845,370,334 - 45,486,036 (+)NCBIGRCr8
mRatBN7.21843,183,854 - 43,299,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1843,183,916 - 43,299,517 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1845,301,632 - 45,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01846,022,691 - 46,063,818 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01843,807,539 - 43,848,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01844,664,310 - 44,779,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1844,716,226 - 44,779,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01843,887,315 - 44,002,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41845,083,452 - 45,126,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11845,122,809 - 45,163,265 (+)NCBI
Celera1841,480,923 - 41,523,804 (+)NCBICelera
Cytogenetic Map18q11NCBI
Tnfaip8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540838,872,007 - 38,990,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540838,872,305 - 38,986,932 (+)NCBIChiLan1.0ChiLan1.0
TNFAIP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24114,545,300 - 114,673,060 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15112,698,975 - 112,826,728 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05114,657,140 - 114,784,819 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15120,442,285 - 120,569,877 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5120,442,500 - 120,569,877 (+)Ensemblpanpan1.1panPan2
TNFAIP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1118,624,106 - 8,685,389 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl118,660,557 - 8,684,374 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha119,700,733 - 9,813,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0118,658,239 - 8,771,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl118,658,262 - 8,771,567 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1118,529,756 - 8,642,940 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0118,586,408 - 8,699,585 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0118,843,971 - 8,957,206 (+)NCBIUU_Cfam_GSD_1.0
Tnfaip8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213131,646,610 - 131,763,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367152,205,977 - 2,322,854 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367152,205,977 - 2,322,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFAIP8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12322,514,427 - 22,636,888 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2322,573,208 - 22,636,936 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603455,673,230 - 55,795,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfaip8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247332,271,825 - 2,396,307 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247332,272,634 - 2,397,002 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TNFAIP8
4579 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001244505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013987586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021079542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021079552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021079563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021079574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021079576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK232094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK236772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK395975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK400356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB471755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU633356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB815564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DT324394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01057975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM153442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000041335   ⟹   ENSSSCP00000059213
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2123,242,480 - 123,284,889 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000048900   ⟹   ENSSSCP00000057223
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2123,152,371 - 123,287,518 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000106395   ⟹   ENSSSCP00000078538
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2123,243,342 - 123,287,941 (+)Ensembl
RefSeq Acc Id: NM_001244505   ⟹   NP_001231434
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,243,251 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013987586   ⟹   XP_013843040
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,252,338 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079542   ⟹   XP_020935201
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,242,189 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079552   ⟹   XP_020935211
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,216,947 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079563   ⟹   XP_020935222
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,152,349 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079574   ⟹   XP_020935233
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,167,029 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021079576   ⟹   XP_020935235
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12123,216,305 - 123,285,154 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020935222   ⟸   XM_021079563
- Peptide Label: isoform X3
- UniProtKB: A0A4X1UA06 (UniProtKB/TrEMBL),   A0A287BL33 (UniProtKB/TrEMBL),   D9ILV0 (UniProtKB/TrEMBL),   A0A8D0TSN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935233   ⟸   XM_021079574
- Peptide Label: isoform X5
- UniProtKB: D9ILV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935235   ⟸   XM_021079576
- Peptide Label: isoform X5
- UniProtKB: D9ILV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935211   ⟸   XM_021079552
- Peptide Label: isoform X2
- UniProtKB: D9ILV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935201   ⟸   XM_021079542
- Peptide Label: isoform X1
- UniProtKB: A0A8D0TSJ3 (UniProtKB/TrEMBL),   A0A287BSQ7 (UniProtKB/TrEMBL),   D9ILV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231434   ⟸   NM_001244505
- UniProtKB: A0A8D1D4H1 (UniProtKB/TrEMBL),   A0A8W4FI27 (UniProtKB/TrEMBL),   A0A8D1RA39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013843040   ⟸   XM_013987586
- Peptide Label: isoform X4
- UniProtKB: A0A287BL33 (UniProtKB/TrEMBL),   A0A4X1UA06 (UniProtKB/TrEMBL),   D9ILV0 (UniProtKB/TrEMBL),   A0A8D0TSN2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000057223   ⟸   ENSSSCT00000048900
Ensembl Acc Id: ENSSSCP00000059213   ⟸   ENSSSCT00000041335
Ensembl Acc Id: ENSSSCP00000078538   ⟸   ENSSSCT00000106395


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000040617 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015078381 UniProtKB/TrEMBL
  ENSSSCG00025037713 UniProtKB/TrEMBL
  ENSSSCG00030053400 UniProtKB/TrEMBL
  ENSSSCG00035074784 UniProtKB/TrEMBL
  ENSSSCG00040033686 UniProtKB/TrEMBL
  ENSSSCG00045020514 UniProtKB/TrEMBL
  ENSSSCG00050035435 UniProtKB/TrEMBL
  ENSSSCG00055021233 UniProtKB/TrEMBL
  ENSSSCG00060041541 UniProtKB/TrEMBL
  ENSSSCG00065064690 UniProtKB/TrEMBL
  ENSSSCG00070015132 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041335 ENTREZGENE
  ENSSSCT00000041335.3 UniProtKB/TrEMBL
  ENSSSCT00000048900 ENTREZGENE
  ENSSSCT00000048900.2 UniProtKB/TrEMBL
  ENSSSCT00000106395 ENTREZGENE
  ENSSSCT00000106395.1 UniProtKB/TrEMBL
  ENSSSCT00015106038.1 UniProtKB/TrEMBL
  ENSSSCT00015106066.1 UniProtKB/TrEMBL
  ENSSSCT00025051299.1 UniProtKB/TrEMBL
  ENSSSCT00025051334.1 UniProtKB/TrEMBL
  ENSSSCT00030074481.1 UniProtKB/TrEMBL
  ENSSSCT00030074509.1 UniProtKB/TrEMBL
  ENSSSCT00035101654.1 UniProtKB/TrEMBL
  ENSSSCT00035101826.1 UniProtKB/TrEMBL
  ENSSSCT00040045349.1 UniProtKB/TrEMBL
  ENSSSCT00040045385.1 UniProtKB/TrEMBL
  ENSSSCT00045034973.1 UniProtKB/TrEMBL
  ENSSSCT00045035075.1 UniProtKB/TrEMBL
  ENSSSCT00050047618.1 UniProtKB/TrEMBL
  ENSSSCT00050047633.1 UniProtKB/TrEMBL
  ENSSSCT00055041714.1 UniProtKB/TrEMBL
  ENSSSCT00055041830.1 UniProtKB/TrEMBL
  ENSSSCT00060056314.1 UniProtKB/TrEMBL
  ENSSSCT00060056325.1 UniProtKB/TrEMBL
  ENSSSCT00065088784.1 UniProtKB/TrEMBL
  ENSSSCT00065088791.1 UniProtKB/TrEMBL
  ENSSSCT00070029734.1 UniProtKB/TrEMBL
  ENSSSCT00070029745.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.160 UniProtKB/TrEMBL
InterPro TNFAIP8-like UniProtKB/TrEMBL
  TNFAIP8_sf UniProtKB/TrEMBL
KEGG Report ssc:100524014 UniProtKB/TrEMBL
NCBI Gene TNFAIP8 ENTREZGENE
PANTHER PTHR12757 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 UniProtKB/TrEMBL
Pfam DUF758 UniProtKB/TrEMBL
UniProt A0A287BL33 ENTREZGENE
  A0A287BSQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U9F7_PIG UniProtKB/TrEMBL
  A0A4X1UA06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TSJ3 ENTREZGENE
  A0A8D0TSN2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1D4H1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RA39 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FI27 ENTREZGENE
  D9ILV0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287BL33 UniProtKB/TrEMBL
  A0A8D0TSJ3 UniProtKB/TrEMBL
  A0A8W4FI27 UniProtKB/TrEMBL
VGNC ID VGNC:94253 ENTREZGENE