.
Dimethyl phthalate - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Dimethyl phthalate
go back to main search page
Accession:CHEBI:4609 term browser browse the term
Definition:A phthalate ester that has formula C10H10O4.
Synonyms:related_synonym: Formula=C10H10O4;   InChI=1S/C10H10O4/c1-13-9(11)7-5-3-4-6-8(7)10(12)14-2/h3-6H,1-2H3;   InChIKey=NIQCNGHVCWTJSM-UHFFFAOYSA-N;   SMILES=COC(=O)c1ccccc1C(=O)OC
 xref: CAS:131-11-3;   Drug_Central:4771;   KEGG:C11233
 xref_mesh: MESH:C024629
 xref: PPDB:2989;   VSDB:2989

 Loading Annotations... 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
Dimethyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions		 ISO dimethyl phthalate results in increased expression of ABCC2 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC2 mRNA		 CTD PMID:35739735 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression		 ISO [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC3 mRNA
dimethyl phthalate results in increased expression of ABCC3 mRNA		 CTD PMID:35739735 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression		 ISO [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC4 mRNA
dimethyl phthalate results in increased expression of ABCC4 mRNA		 CTD PMID:35739735 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
multiple interactions		 ISO dimethyl phthalate results in increased expression of ABCG2 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCG2 mRNA		 CTD PMID:35739735 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Afp alpha-fetoprotein affects binding EXP dimethyl phthalate binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ar androgen receptor multiple interactions ISO dimethyl phthalate analog inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; dimethyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:20943248 PMID:28571686 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression EXP dimethyl phthalate results in increased expression of BAK1 mRNA CTD PMID:35598668 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BAX mRNA CTD PMID:35598668 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BCL2 mRNA CTD PMID:35598668 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP dimethyl phthalate results in increased expression of BID mRNA CTD PMID:35598668 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp2 caspase 2 increases expression EXP dimethyl phthalate results in increased expression of CASP2 mRNA CTD PMID:35598668 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases expression EXP dimethyl phthalate results in increased expression of CASP3 mRNA CTD PMID:35598668 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases expression EXP dimethyl phthalate results in increased expression of CASP7 mRNA CTD PMID:35598668 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases expression EXP dimethyl phthalate results in increased expression of CASP8 mRNA CTD PMID:35598668 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression
multiple interactions		 EXP
ISO		 dimethyl phthalate results in increased expression of CYP11A1 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP11A1 mRNA		 CTD PMID:26472102 PMID:35739735 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP dimethyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP dimethyl phthalate results in decreased activity of CYP2B1 protein CTD PMID:27432241 NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Fadd Fas associated via death domain increases expression EXP dimethyl phthalate results in increased expression of FADD mRNA CTD PMID:35598668 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP dimethyl phthalate results in increased expression of FAS mRNA CTD PMID:35598668 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression EXP dimethyl phthalate results in increased expression of FASLG mRNA CTD PMID:35598668 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of HSD3B1 mRNA CTD PMID:35739735 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Ifng interferon gamma decreases expression EXP dimethyl phthalate results in decreased expression of IFNG protein CTD PMID:35598668 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP dimethyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il4 interleukin 4 decreases expression EXP dimethyl phthalate results in decreased expression of IL4 protein CTD PMID:35598668 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 decreases expression EXP dimethyl phthalate results in decreased expression of IL6 protein CTD PMID:35598668 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP dimethyl phthalate results in decreased expression of MSH2 mRNA CTD PMID:26472102 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Myocd myocardin decreases expression EXP dimethyl phthalate results in decreased expression of MYOCD mRNA CTD PMID:26472102 NCBI chr10:50,332,356...50,426,819
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects binding ISO dimethyl phthalate binds to NR1I3 protein CTD PMID:25938866 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO dimethyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO dimethyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO dimethyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO dimethyl phthalate binds to RXRA protein CTD PMID:23843199 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO dimethyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,818,707...4,824,968
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO dimethyl phthalate binds to RXRG protein CTD PMID:23843199 NCBI chr13:82,276,330...82,318,097
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression
multiple interactions		 EXP
ISO		 dimethyl phthalate results in decreased expression of SCARB1 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of SCARB1 mRNA		 CTD PMID:26472102 PMID:35739735 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP dimethyl phthalate results in decreased expression of SOD1 protein CTD PMID:35598668 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 EXP
ISO		 dimethyl phthalate results in decreased expression of STAR mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in decreased expression of STAR mRNA		 CTD PMID:26472102 PMID:35739735 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      application 19697
        fuel 11364
          methanol 3989
            methyl ester 3934
              Dimethyl phthalate 37
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      aromatic carboxylic acid 13805
                                        benzoic acids 13788
                                          benzenedicarboxylic acid 10783
                                            phthalic acid 10623
                                              phthalate ester 10623
                                                Dimethyl phthalate 37
paths to the root