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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases degradation increases phosphorylation increases expression |
EXP ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] Oleic Acid results in increased degradation of ABCA1 protein Oleic Acid results in increased phosphorylation of ABCA1 protein Oleic Acid results in increased expression of ABCA1 mRNA |
CTD |
PMID:16118212 PMID:18356535 PMID:30547786 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
increases expression |
ISO |
Oleic Acid results in increased expression of ABCB11 mRNA |
CTD |
PMID:32738331 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCD3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA] |
CTD |
PMID:18489776 |
|
NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666
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G |
ABCG1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of ABCG1 mRNA; Oleic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 |
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NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244
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G |
ABCG2 |
ATP binding cassette subfamily G member 2 (JR blood group) |
increases expression |
EXP |
Oleic Acid results in increased expression of ABCG2 mRNA |
CTD |
PMID:22819932 |
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NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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G |
ACAA1 |
acetyl-CoA acyltransferase 1 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242
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G |
ACAA2 |
acetyl-CoA acyltransferase 2 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of ACAA2 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAA2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
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G |
ACACA |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA; cyhalothrin promotes the reaction [Oleic Acid results in increased expression of ACACA protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA] |
CTD |
PMID:30611723 PMID:36529352 PMID:36905866 |
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NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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G |
ACACB |
acetyl-CoA carboxylase beta |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACB mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
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G |
ACAD9 |
acyl-CoA dehydrogenase family member 9 |
multiple interactions increases expression |
EXP |
[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of ACAD9 mRNA] |
CTD |
PMID:31340670 |
|
NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003
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G |
ACADL |
acyl-CoA dehydrogenase long chain |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
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G |
ACADM |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA |
CTD |
PMID:26190035 PMID:30611723 |
|
NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
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G |
ACADS |
acyl-CoA dehydrogenase short chain |
multiple interactions increases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADS mRNA Oleic Acid results in increased expression of ACADS mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008
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G |
ACADVL |
acyl-CoA dehydrogenase very long chain |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADVL mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADVL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266
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G |
ACAT1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603
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G |
ACAT2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
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G |
ACLY |
ATP citrate lyase |
multiple interactions decreases expression |
EXP |
[[Vehicle Emissions results in increased abundance of Particulate Matter] which co-treated with Oleic Acid] results in decreased expression of ACLY mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNA Oleic Acid results in decreased expression of ACLY mRNA |
CTD |
PMID:30611723 PMID:31340670 |
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NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
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G |
ACOT1 |
acyl-CoA thioesterase 1 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796
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G |
ACOT12 |
acyl-CoA thioesterase 12 |
multiple interactions increases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT12 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA Oleic Acid results in increased expression of ACOT12 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:81,308,609...81,394,134
Ensembl chr 5:81,329,996...81,394,179
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G |
ACOT4 |
acyl-CoA thioesterase 4 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:73,591,873...73,595,766
Ensembl chr14:73,591,873...73,595,766
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G |
ACOT6 |
acyl-CoA thioesterase 6 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr14:73,610,945...73,619,888
Ensembl chr14:73,610,945...73,619,888
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G |
ACOT7 |
acyl-CoA thioesterase 7 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT7 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT7 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
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G |
ACOT8 |
acyl-CoA thioesterase 8 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr20:45,841,721...45,857,392
Ensembl chr20:45,841,721...45,857,405
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G |
ACOX1 |
acyl-CoA oxidase 1 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [tesaglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
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G |
ACOX2 |
acyl-CoA oxidase 2 |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of ACOX2 mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283
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G |
ACSL1 |
acyl-CoA synthetase long chain family member 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
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G |
ACSL3 |
acyl-CoA synthetase long chain family member 3 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
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G |
ACSL4 |
acyl-CoA synthetase long chain family member 4 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr X:109,641,335...109,733,257
Ensembl chr X:109,624,244...109,733,403
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G |
ACSL5 |
acyl-CoA synthetase long chain family member 5 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
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G |
ACTA2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA Oleic Acid results in increased expression of ACTA2 mRNA |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of ADIPOQ mRNA sophocarpine inhibits the reaction [Oleic Acid results in decreased expression of ADIPOQ mRNA] |
CTD |
PMID:23395669 |
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NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
ADIPOR2 |
adiponectin receptor 2 |
decreases expression |
ISO |
oleic acid cotreated with ethanol decreases expression of adipor2 mRNA in rat primary hepatocytes |
RGD |
PMID:21194380 |
RGD:24922202 |
NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
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G |
AGPAT1 |
1-acylglycerol-3-phosphate O-acyltransferase 1 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:32,168,212...32,178,108
Ensembl chr 6:32,168,212...32,178,096
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G |
AGPAT2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of AGPAT2 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457
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G |
AGPAT5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:6,708,642...6,761,503
Ensembl chr 8:6,708,642...6,761,503
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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G |
AKR7L |
aldo-keto reductase family 7 like (gene/pseudogene) |
decreases expression |
EXP |
Oleic Acid results in decreased expression of AKR7L protein |
CTD |
PMID:37117602 |
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NCBI chr 1:19,265,982...19,274,122
Ensembl chr 1:19,265,982...19,274,194
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
ISO EXP |
Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:14604813 PMID:25536389 PMID:26847930 |
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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G |
ALB |
albumin |
multiple interactions affects binding decreases secretion |
EXP |
[ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Oleic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [Oleic Acid co-treated with muraglitazar] results in increased expression of ALB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ALB mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ALB mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein]; Quercetin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein] |
CTD |
PMID:23348005 PMID:24534255 PMID:25451573 PMID:38103844 |
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NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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G |
ALDH1A1 |
aldehyde dehydrogenase 1 family member A1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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G |
ANGPTL4 |
angiopoietin like 4 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
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G |
ANXA2 |
annexin A2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
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G |
APOA1 |
apolipoprotein A1 |
multiple interactions |
EXP |
Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
|
NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
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G |
APOA4 |
apolipoprotein A4 |
increases expression |
EXP |
Oleic Acid results in increased expression of APOA4 mRNA |
CTD |
PMID:26739624 |
|
NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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G |
APOA5 |
apolipoprotein A5 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of APOA5 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420
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G |
APOB |
apolipoprotein B |
multiple interactions decreases expression increases expression |
EXP ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]; Oleic Acid results in increased expression of and results in increased secretion of APOB protein Oleic Acid results in decreased expression of APOB mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]; Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] |
CTD |
PMID:12048068 PMID:15618547 PMID:17237316 PMID:19383982 PMID:26854922 PMID:30611723 PMID:32918399 More...
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NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
APOC3 |
apolipoprotein C3 |
multiple interactions |
EXP |
[Oleic Acid co-treated with muraglitazar] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of APOC3 mRNA |
CTD |
PMID:24534255 |
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NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
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G |
APOC4 |
apolipoprotein C4 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:44,942,237...44,945,496
Ensembl chr19:44,942,237...44,945,496
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G |
APOE |
apolipoprotein E |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOE mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOE mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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G |
ARG1 |
arginase 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
EXP ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of ATF6 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATG5 |
autophagy related 5 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein] |
CTD |
PMID:36905866 |
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NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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G |
ATG7 |
autophagy related 7 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein] |
CTD |
PMID:36905866 |
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NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
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G |
B4GALT5 |
beta-1,4-galactosyltransferase 5 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:49,632,945...49,713,878
Ensembl chr20:49,632,945...49,713,878
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G |
BACE1 |
beta-secretase 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein] |
CTD |
PMID:37009739 |
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NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA |
CTD |
PMID:32369900 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA |
CTD |
PMID:32369900 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
CASP3 |
caspase 3 |
multiple interactions increases cleavage |
EXP ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA Oleic Acid results in increased cleavage of CASP3 protein Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased cleavage of CASP3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:36273635 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP9 |
caspase 9 |
multiple interactions increases cleavage |
ISO EXP |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA |
CTD |
PMID:14604813 PMID:32369900 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
multiple interactions increases activity decreases activity |
EXP ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; Quercetin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein] Oleic Acid results in increased activity of CAT protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased activity of CAT protein]; gossypin inhibits the reaction [Oleic Acid results in increased activity of CAT protein] |
CTD |
PMID:23348005 PMID:26854922 PMID:30547786 PMID:37696682 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV2 |
caveolin 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541
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G |
CD36 |
CD36 molecule (CD36 blood group) |
multiple interactions increases expression |
ISO EXP |
GW 4064 inhibits the reaction [Oleic Acid results in increased expression of CD36 protein] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] Oleic Acid results in increased expression of CD36 mRNA [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA |
CTD |
PMID:23371517 PMID:28552552 PMID:30611723 PMID:36347319 PMID:38092172 PMID:38103844 More...
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NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA |
CTD |
PMID:32369900 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CIDEC |
cell death inducing DFFA like effector c |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
COX10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of COX10 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:14,069,504...14,208,677
Ensembl chr17:14,069,490...14,231,736
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G |
CPT1A |
carnitine palmitoyltransferase 1A |
increases expression decreases expression multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of CPT1A mRNA Oleic Acid results in decreased expression of CPT1A mRNA [Starch co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of CPT1A mRNA [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT1A mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of CPT1A mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:11171094 PMID:24534255 PMID:25048947 PMID:26190035 PMID:26854922 PMID:26895660 PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 More...
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NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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G |
CPT2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of CPT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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G |
CREBBP |
CREB binding protein |
decreases expression |
ISO |
Oleic Acid results in decreased expression of CREBBP mRNA |
CTD |
PMID:24349266 |
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NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
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G |
CRP |
C-reactive protein |
multiple interactions |
EXP |
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein |
CTD |
PMID:17237316 |
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NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases expression |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; Quercetin inhibits the reaction [Oleic Acid results in increased expression of CXCL8 protein]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of CXCL8 protein]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of CXCL8 protein] |
CTD |
PMID:23348005 PMID:30547786 |
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CYCS |
cytochrome c, somatic |
multiple interactions |
EXP |
[Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with letrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein |
CTD |
PMID:24161488 PMID:27016407 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions increases expression |
EXP |
[Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 mRNA]; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 protein] Oleic Acid results in increased expression of CYP1A1 mRNA; Oleic Acid results in increased expression of CYP1A1 protein |
CTD |
PMID:31730885 |
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions decreases expression |
EXP |
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA] |
CTD |
PMID:30611723 |
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NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP24A1 |
cytochrome P450 family 24 subfamily A member 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
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G |
CYP26A1 |
cytochrome P450 family 26 subfamily A member 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
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G |
CYP26B1 |
cytochrome P450 family 26 subfamily B member 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862
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G |
CYP2A6 |
cytochrome P450 family 2 subfamily A member 6 |
increases expression |
EXP |
Oleic Acid results in increased expression of CYP2A6 mRNA; Oleic Acid results in increased expression of CYP2A6 protein |
CTD |
PMID:28555106 |
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NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
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G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
multiple interactions decreases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA] |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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G |
CYP2C9 |
cytochrome P450 family 2 subfamily C member 9 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP2C65 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:26854922 PMID:30611723 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of CYP3A4 mRNA; Oleic Acid results in decreased expression of CYP3A4 protein Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP3A4 mRNA] |
CTD |
PMID:26739624 PMID:30611723 |
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NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
CYP4A11 |
cytochrome P450 family 4 subfamily A member 11 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP4A11 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CYP4A11 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
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G |
CYP4A22 |
cytochrome P450 family 4 subfamily A member 22 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:26854922 |
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NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
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G |
CYP4F8 |
cytochrome P450 family 4 subfamily F member 8 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
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G |
CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of CYP7A1 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:32738331 PMID:38103844 |
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NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions |
EXP ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 mRNA]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:37009739 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DECR1 |
2,4-dienoyl-CoA reductase 1 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of DECR1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:90,001,477...90,053,633
Ensembl chr 8:90,001,405...90,053,633
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G |
DERL1 |
derlin 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:123,013,170...123,042,302
Ensembl chr 8:123,013,170...123,042,302
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G |
DGAT1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
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G |
DGAT2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
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G |
DHDDS |
dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DHDDS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of DHDDS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:26,432,321...26,471,306
Ensembl chr 1:26,432,282...26,471,306
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G |
DNM1L |
dynamin 1 like |
affects phosphorylation |
EXP |
Oleic Acid affects the phosphorylation of DNM1L protein |
CTD |
PMID:36273635 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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G |
DST |
dystonin |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830
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G |
DYNC1H1 |
dynein cytoplasmic 1 heavy chain 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443
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G |
DYNC1I1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322
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G |
E2F1 |
E2F transcription factor 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of E2F1 protein |
CTD |
PMID:16027227 |
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NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
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G |
ECH1 |
enoyl-CoA hydratase 1 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECH1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of ECH1 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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G |
ECHS1 |
enoyl-CoA hydratase, short chain 1 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECHS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
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G |
EDN1 |
endothelin 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of EDN1 mRNA; Oleic Acid results in decreased expression of EDN1 protein |
CTD |
PMID:16895544 |
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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G |
EGFR |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein] Oleic Acid results in increased phosphorylation of EGFR protein |
CTD |
PMID:27447558 PMID:30547786 PMID:38103844 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EHHADH |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of EHHADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA |
CTD |
PMID:30547786 PMID:32369900 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
ELOVL5 |
ELOVL fatty acid elongase 5 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:53,267,404...53,348,950
Ensembl chr 6:53,267,398...53,349,179
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G |
ELOVL6 |
ELOVL fatty acid elongase 6 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
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G |
ENO3 |
enolase 3 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
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G |
ERLIN1 |
ER lipid raft associated 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
FABP1 |
fatty acid binding protein 1 |
affects binding decreases expression multiple interactions |
ISO EXP |
Oleic Acid binds to FABP1 protein Oleic acid binds to Fabp1 protein Oleic Acid results in decreased expression of FABP1 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FABP1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FABP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA; Dibutyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Oleic Acid inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] Bezafibrate inhibits the reaction [Oleic Acid binds to FABP1 protein] |
CTD RGD |
PMID:2328261 PMID:30547786 PMID:30611723 PMID:31110286 PMID:38092172 PMID:1939124 More...
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RGD:1626448 |
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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G |
FABP2 |
fatty acid binding protein 2 |
affects binding |
ISO |
FABP2 protein modified form binds to Oleic Acid |
CTD |
PMID:16137630 |
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NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
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G |
FABP4 |
fatty acid binding protein 4 |
multiple interactions affects localization increases expression |
ISO EXP |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA Oleic Acid analog affects the localization of FABP4 protein Oleic Acid results in increased expression of FABP4 mRNA |
CTD |
PMID:8536680 PMID:26739624 PMID:27939595 |
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NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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G |
FAS |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FAS mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein] Oleic Acid results in increased expression of FAS mRNA |
CTD |
PMID:26190035 PMID:32918399 PMID:36347319 PMID:36905866 |
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NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASN |
fatty acid synthase |
multiple interactions |
EXP ISO |
[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FASN mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein; [Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein] [Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA |
CTD |
PMID:24534255 PMID:26854922 PMID:26895660 PMID:30611723 PMID:33508418 PMID:36529352 PMID:38103844 More...
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FDFT1 |
farnesyl-diphosphate farnesyltransferase 1 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FDFT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395
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G |
FDPS |
farnesyl diphosphate synthase |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of FDPS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666
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G |
FFAR1 |
free fatty acid receptor 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of FFAR1 mRNA |
CTD |
PMID:24349266 |
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NCBI chr19:35,347,902...35,353,864
Ensembl chr19:35,347,902...35,353,864
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G |
FGF21 |
fibroblast growth factor 21 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA |
CTD |
PMID:30547786 |
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NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
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G |
FIS1 |
fission, mitochondrial 1 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
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G |
FLOT1 |
flotillin 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732
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G |
FNTA |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:43,056,323...43,085,785
Ensembl chr 8:43,034,194...43,085,788
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G |
FNTB |
farnesyltransferase, CAAX box, subunit beta |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:64,986,895...65,062,650
Ensembl chr14:64,986,895...65,062,652
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G |
FOXA1 |
forkhead box A1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059
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G |
FOXO1 |
forkhead box O1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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G |
FTH1 |
ferritin heavy chain 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein] |
CTD |
PMID:32976958 |
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NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
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G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
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NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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G |
GCG |
glucagon |
multiple interactions increases secretion |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein] |
CTD |
PMID:36905866 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] |
CTD |
PMID:36905866 |
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NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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G |
GGPS1 |
geranylgeranyl diphosphate synthase 1 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of GGPS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:235,327,216...235,344,532
Ensembl chr 1:235,327,350...235,344,532
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G |
GGT1 |
gamma-glutamyltransferase 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
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G |
GLP1R |
glucagon like peptide 1 receptor |
multiple interactions affects localization |
ISO |
[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; Chloroquine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]; Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein; wortmannin inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] Oleic Acid affects the localization of GLP1R protein |
CTD |
PMID:22925809 |
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NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303
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G |
GLUD1 |
glutamate dehydrogenase 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
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G |
GLUD2 |
glutamate dehydrogenase 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of GLUD2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr X:121,047,610...121,050,094
Ensembl chr X:121,047,610...121,050,094
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G |
GNAT3 |
G protein subunit alpha transducin 3 |
multiple interactions |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 7:80,458,635...80,512,064
Ensembl chr 7:80,458,635...80,512,064
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G |
GPAM |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions |
EXP |
[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein; acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] |
CTD |
PMID:33508418 |
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NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
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G |
GPAT3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of GPAT3 mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT3 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of GPAT3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 4:83,535,587...83,605,875
Ensembl chr 4:83,535,914...83,605,875
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G |
GPAT4 |
glycerol-3-phosphate acyltransferase 4 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:41,578,200...41,625,001
Ensembl chr 8:41,577,187...41,625,001
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] |
CTD |
PMID:32976958 |
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NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein] |
CTD |
PMID:32976958 |
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NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
EXP |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25536389 |
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NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSTA1 |
glutathione S-transferase alpha 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
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G |
HADH |
hydroxyacyl-CoA dehydrogenase |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADH mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241
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G |
HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions increases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADHA mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHA mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHA mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
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G |
HADHB |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of HADHB mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHB mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHB mRNA]; Oleic Acid promotes the reaction [GW 7647 results in increased expression of HADHB mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
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G |
HAVCR1 |
hepatitis A virus cellular receptor 1 |
increases secretion |
EXP |
Oleic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:31686351 |
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NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein |
CTD |
PMID:30547786 |
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NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
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G |
HILPDA |
hypoxia inducible lipid droplet associated |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein |
CTD |
PMID:30547786 |
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NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418
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G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
EXP ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HMGCR mRNA [[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein |
CTD |
PMID:30611723 PMID:31299271 |
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NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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G |
HMGCS1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
multiple interactions |
EXP |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of HMGCS1 mRNA |
CTD |
PMID:36423729 |
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NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP |
[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] |
CTD |
PMID:26634892 PMID:32976958 PMID:36905866 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNF4A |
hepatocyte nuclear factor 4 alpha |
multiple interactions increases expression |
ISO EXP |
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of HNF4A protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA |
CTD |
PMID:23395669 PMID:30547786 |
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NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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G |
HSDL2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of HSPA5 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA |
CTD |
PMID:24349266 PMID:30547786 PMID:32976987 PMID:37009739 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
IL18 |
interleukin 18 |
multiple interactions |
EXP |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein |
CTD |
PMID:36423729 |
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NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1A |
interleukin 1 alpha |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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G |
IL1B |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL1B protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA] |
CTD |
PMID:26190035 PMID:36423729 PMID:37009739 PMID:37696682 PMID:38103844 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL6 |
interleukin 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein] Oleic Acid results in decreased expression of IL6 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of IL6 protein] Oleic Acid results in increased expression of IL6 mRNA; Oleic Acid results in increased expression of IL6 protein |
CTD |
PMID:25348860 PMID:26634892 PMID:30611723 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
INS |
insulin |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased uptake of Oleic Acid |
CTD |
PMID:10777552 PMID:11292061 |
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NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions increases secretion |
ISO |
Oleic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein] Oleic Acid results in increased secretion of INS1 protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] |
CTD |
PMID:24349266 PMID:26847930 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
INSR |
insulin receptor |
multiple interactions decreases phosphorylation |
EXP |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:25536389 |
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NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
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G |
IRS2 |
insulin receptor substrate 2 |
multiple interactions |
ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein]; Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] |
CTD |
PMID:14604813 |
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NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
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G |
IYD |
iodotyrosine deiodinase |
multiple interactions |
EXP |
Oleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 6:150,369,012...150,405,969
Ensembl chr 6:150,368,892...150,405,969
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G |
JAK1 |
Janus kinase 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein |
CTD |
PMID:30547786 |
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NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
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G |
JAK2 |
Janus kinase 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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G |
KEAP1 |
kelch like ECH associated protein 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
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NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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G |
LAMB1 |
laminin subunit beta 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213
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G |
LDLR |
low density lipoprotein receptor |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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G |
LEP |
leptin |
decreases expression increases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of LEP mRNA Oleic Acid results in increased expression of LEP mRNA sophocarpine inhibits the reaction [Oleic Acid results in increased expression of LEP mRNA] |
CTD |
PMID:9002984 PMID:23395669 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LIPC |
lipase C, hepatic type |
multiple interactions decreases expression |
ISO EXP |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid Oleic Acid results in decreased expression of LIPC mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of LIPC mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LIPC mRNA; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of LIPC mRNA] |
CTD |
PMID:24777581 PMID:30611723 PMID:32918399 |
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NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
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G |
LIPG |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid |
CTD |
PMID:24777581 |
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NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
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G |
LOX |
lysyl oxidase |
increases activity |
ISO |
Oleic Acid results in increased activity of LOX protein |
CTD |
PMID:26240151 |
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NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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G |
LPIN1 |
lipin 1 |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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G |
LPIN2 |
lipin 2 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr18:2,916,994...3,013,144
Ensembl chr18:2,885,296...3,013,144
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G |
LPIN3 |
lipin 3 |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of LPIN3 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr20:41,340,821...41,360,582
Ensembl chr20:41,340,821...41,360,582
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:30547786 PMID:36905866 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAP3K8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833
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G |
MAP4K4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690
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G |
MCAT |
malonyl-CoA-acyl carrier protein transacylase |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MCAT mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MCAT mRNA |
CTD |
PMID:30611723 |
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NCBI chr22:43,132,206...43,143,398
Ensembl chr22:43,132,209...43,143,398
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G |
MECR |
mitochondrial trans-2-enoyl-CoA reductase |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:29,167,696...29,230,934
Ensembl chr 1:29,192,657...29,230,942
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G |
MFF |
mitochondrial fission factor |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA |
CTD |
PMID:32369900 |
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NCBI chr 2:227,325,251...227,357,836
Ensembl chr 2:227,325,151...227,357,833
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G |
MFN1 |
mitofusin 1 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
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G |
MGLL |
monoglyceride lipase |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] affects the reaction [Chlorpyrifos results in decreased activity of MGLL protein] |
CTD |
PMID:35151815 |
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NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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G |
MIR497 |
microRNA 497 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA] |
CTD |
PMID:37009739 |
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NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022
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G |
MLKL |
mixed lineage kinase domain like pseudokinase |
multiple interactions increases phosphorylation |
EXP |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein] |
CTD |
PMID:36273635 |
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NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960
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G |
MLXIPL |
MLX interacting protein like |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543
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G |
MMP2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA |
CTD |
PMID:26187275 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein] |
CTD |
PMID:38103844 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MT2A |
metallothionein 2A |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA |
CTD |
PMID:26854922 |
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NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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G |
MTTP |
microsomal triglyceride transfer protein |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of MTTP mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of MTTP mRNA] |
CTD |
PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 PMID:38092172 |
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NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
EXP ISO |
[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA] Oleic Acid results in increased expression of NFE2L2 mRNA; Oleic Acid results in increased expression of NFE2L2 protein |
CTD |
PMID:26634892 PMID:26847930 PMID:28555106 PMID:32976958 PMID:36905866 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NOS3 |
nitric oxide synthase 3 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of NOS3 mRNA |
CTD |
PMID:16895544 |
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein] |
CTD |
PMID:36905866 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
NR0B2 |
nuclear receptor subfamily 0 group B member 2 |
decreases expression increases expression multiple interactions |
EXP ISO |
Oleic Acid results in decreased expression of NR0B2 mRNA Oleic Acid results in increased expression of NR0B2 mRNA [Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of NR0B2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:30611723 PMID:32738331 |
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NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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G |
NR1H3 |
nuclear receptor subfamily 1 group H member 3 |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with rosiglitazone] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with tesaglitazar] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with troglitazone] affects the expression of NR1H3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA |
CTD |
PMID:24534255 PMID:26190035 |
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NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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G |
NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
multiple interactions decreases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of NR1H4 mRNA; [Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA Oleic Acid results in decreased expression of NR1H4 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1I3 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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G |
NRF1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082
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G |
P2RX7 |
purinergic receptor P2X 7 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] |
CTD |
PMID:25348860 |
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NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
increases cleavage increases activity multiple interactions |
EXP ISO |
Oleic Acid results in increased cleavage of PARP1 protein Oleic Acid results in increased activity of PARP1 protein N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in increased activity of PARP1 protein] [NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in increased activity of PARP1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:21132278 PMID:25536389 PMID:30165350 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PC |
pyruvate carboxylase |
decreases expression |
ISO |
Oleic Acid results in decreased expression of PC mRNA |
CTD |
PMID:24349266 |
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NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
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G |
PCK1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
ISO EXP |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of PCK1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PCK1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 PMID:9518257 PMID:26847930 PMID:30611723 |
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NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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G |
PDGFB |
platelet derived growth factor subunit B |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of PDGFB mRNA Sorafenib inhibits the reaction [Oleic Acid results in increased expression of PDGFB mRNA] |
CTD |
PMID:32918399 |
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NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
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G |
PDK4 |
pyruvate dehydrogenase kinase 4 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of PDK4 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein |
CTD |
PMID:26739624 PMID:30547786 |
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NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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G |
PDSS1 |
decaprenyl diphosphate synthase subunit 1 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PDSS1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PDSS1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr10:26,697,701...26,746,798
Ensembl chr10:26,697,701...26,746,798
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G |
PEBP1 |
phosphatidylethanolamine binding protein 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584
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G |
PECR |
peroxisomal trans-2-enoyl-CoA reductase |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of PECR mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of PECR mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955
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G |
PGAM5 |
PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
multiple interactions |
EXP |
PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
|
NCBI chr12:132,710,842...132,722,734
Ensembl chr12:132,710,819...132,722,734
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G |
PIK3C2A |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA |
CTD |
PMID:30547786 |
|
NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986
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G |
PINK1 |
PTEN induced kinase 1 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
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G |
PKLR |
pyruvate kinase L/R |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PLD1 |
phospholipase D1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950
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G |
PLEK |
pleckstrin |
multiple interactions |
EXP |
Oleic Acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453
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G |
PLIN1 |
perilipin 1 |
increases expression |
EXP |
Oleic Acid results in increased expression of PLIN1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427
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G |
PLIN2 |
perilipin 2 |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA; Oleic Acid promotes the reaction [LG 100268 results in increased expression of PLIN2 protein]; Oleic Acid promotes the reaction [pirinixic acid results in increased expression of PLIN2 protein] Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein] Oleic Acid results in increased expression of PLIN2 mRNA; Oleic Acid results in increased expression of PLIN2 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:16489205 PMID:24534255 PMID:25048947 PMID:26739624 PMID:30547786 PMID:30611723 PMID:31570772 PMID:38092172 More...
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NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
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G |
PLIN3 |
perilipin 3 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr19:4,838,341...4,867,667
Ensembl chr19:4,838,341...4,867,694
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G |
PLIN4 |
perilipin 4 |
multiple interactions increases expression |
EXP |
Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; Troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA] |
CTD |
PMID:24534255 |
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NCBI chr19:4,502,192...4,518,486
Ensembl chr19:4,502,192...4,518,486
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G |
PLIN5 |
perilipin 5 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] |
CTD |
PMID:25048947 |
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NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,224
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G |
PLPP6 |
phospholipid phosphatase 6 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:4,662,294...4,665,258
Ensembl chr 9:4,662,294...4,665,258
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G |
PNPLA3 |
patatin like phospholipase domain containing 3 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488
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G |
PON1 |
paraoxonase 1 |
multiple interactions decreases activity |
EXP |
[Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] Oleic Acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15104111 PMID:15375178 |
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NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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G |
PPARA |
peroxisome proliferator activated receptor alpha |
multiple interactions affects binding increases expression affects abundance decreases expression increases activity |
ISO EXP |
Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Oleic Acid]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid inhibits the reaction [troglitazone results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP2C65 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] Oleic Acid binds to PPARA protein Oleic Acid results in increased expression of PPARA mRNA; Oleic Acid results in increased expression of PPARA protein [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] Oleic Acid results in decreased expression of PPAR mRNA; Oleic Acid results in decreased expression of PPARA mRNA; Oleic Acid results in decreased expression of PPARA protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; [Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of PPARA mRNA]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased activity of and results in increased localization of PPARA protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PPARA protein]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid results in increased activity of and results in increased localization of PPARA protein; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein] Oleic Acid results in increased activity of PPARA protein |
CTD |
PMID:9688458 PMID:10403814 PMID:11056218 PMID:15491415 PMID:15949695 PMID:16731579 PMID:18154422 PMID:18489776 PMID:23603006 PMID:23619606 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30547786 PMID:30611723 PMID:31340670 PMID:31730885 PMID:33508418 PMID:35752307 PMID:36347319 PMID:38103844 More...
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NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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PPARD |
peroxisome proliferator activated receptor delta |
increases expression multiple interactions decreases expression |
EXP ISO |
Oleic Acid results in increased expression of PPARD mRNA Oleic Acid binds to and results in increased activity of PPARB protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; Oleic Acid binds to and results in increased activity of PPARB protein; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA] Oleic Acid results in decreased expression of PPARD mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA; Oleic Acid binds to and results in increased activity of PPARB protein |
CTD |
PMID:11172467 PMID:16731579 PMID:24349266 PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 More...
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NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
increases expression affects binding multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of PPARG mRNA Oleic Acid binds to PPARG protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] [cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARG mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein]; Oleic Acid binds to and results in increased activity of PPARG protein Oleic Acid results in increased expression of PPARG mRNA; Oleic Acid results in increased expression of PPARG protein |
CTD |
PMID:11172467 PMID:18154422 PMID:24534255 PMID:24998974 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27131391 PMID:30611723 PMID:35752307 PMID:36529352 PMID:36905866 PMID:38103844 More...
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PPARGC1A |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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G |
PRKAA1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
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G |
PRKAA2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP |
dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26634892 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
RAB18 |
RAB18, member RAS oncogene family |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:27,504,304...27,542,239
Ensembl chr10:27,504,174...27,543,207
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G |
RABGGTA |
Rab geranylgeranyltransferase subunit alpha |
multiple interactions |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:24,265,538...24,271,627
Ensembl chr14:24,265,538...24,271,611
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G |
RABGGTB |
Rab geranylgeranyltransferase subunit beta |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of RABGGTB mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:75,786,194...75,795,090
Ensembl chr 1:75,786,197...75,795,086
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G |
RB1 |
RB transcriptional corepressor 1 |
decreases phosphorylation |
EXP |
Oleic Acid results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16027227 |
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NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
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G |
RHEB |
Ras homolog, mTORC1 binding |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120
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G |
RHOB |
ras homolog family member B |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
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G |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
EXP |
Oleic Acid results in increased phosphorylation of RIPK1 protein necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein] |
CTD |
PMID:36273635 |
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NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187
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G |
RIPK3 |
receptor interacting serine/threonine kinase 3 |
increases phosphorylation multiple interactions |
EXP |
Oleic Acid results in increased phosphorylation of RIPK3 protein necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022
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G |
ROCK2 |
Rho associated coiled-coil containing protein kinase 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein |
CTD |
PMID:30547786 |
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NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330
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G |
RXRA |
retinoid X receptor alpha |
multiple interactions |
EXP |
Oleic Acid binds to and results in increased activity of RXRA protein |
CTD |
PMID:16731579 PMID:27131391 |
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NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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G |
SCD |
stearoyl-CoA desaturase |
multiple interactions decreases expression |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of SCD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA] Oleic Acid results in decreased expression of SCD mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 PMID:36423729 PMID:38092172 PMID:38103844 More...
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NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
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G |
SCD5 |
stearoyl-CoA desaturase 5 |
multiple interactions decreases expression |
EXP |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD5 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD5 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SCD5 mRNA Oleic Acid results in decreased expression of SCD5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 4:82,629,539...82,798,796
Ensembl chr 4:82,629,539...82,798,796
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G |
SCP2 |
sterol carrier protein 2 |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SCP2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
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G |
SERPINE1 |
serpin family E member 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] |
CTD |
PMID:11292061 PMID:30547786 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SIRT1 |
sirtuin 1 |
increases expression decreases activity multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of SIRT1 protein Oleic Acid results in decreased activity of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased activity of SIRT1 protein]; NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein] [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein |
CTD |
PMID:24349266 PMID:25536389 PMID:26854922 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SIRT4 |
sirtuin 4 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of SIRT4 mRNA |
CTD |
PMID:24349266 |
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NCBI chr12:120,291,780...120,313,249
Ensembl chr12:120,302,316...120,313,249
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G |
SLC13A1 |
solute carrier family 13 member 1 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 7:123,113,531...123,199,971
Ensembl chr 7:123,113,531...123,199,972
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G |
SLC16A9 |
solute carrier family 16 member 9 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr10:59,650,764...59,710,079
Ensembl chr10:59,650,764...59,736,002
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G |
SLC25A11 |
solute carrier family 25 member 11 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of SLC25A11 mRNA |
CTD |
PMID:24349266 |
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NCBI chr17:4,937,130...4,940,046
Ensembl chr17:4,937,130...4,940,053
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G |
SLC25A20 |
solute carrier family 25 member 20 |
increases expression multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of SLC25A20 protein [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC25A20 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:24349266 PMID:30611723 |
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NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904
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G |
SLC25A22 |
solute carrier family 25 member 22 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of SLC25A22 mRNA |
CTD |
PMID:24349266 |
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NCBI chr11:790,475...798,281
Ensembl chr11:790,475...798,281
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G |
SLC27A1 |
solute carrier family 27 member 1 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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G |
SLC27A2 |
solute carrier family 27 member 2 |
multiple interactions |
EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SLC27A2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385
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G |
SLC27A4 |
solute carrier family 27 member 4 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470
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G |
SLC2A1 |
solute carrier family 2 member 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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G |
SLC2A2 |
solute carrier family 2 member 2 |
increases expression multiple interactions |
EXP |
Oleic Acid results in increased expression of SLC2A2 mRNA [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of SLC2A2 mRNA] |
CTD |
PMID:12048068 PMID:30547786 |
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NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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G |
SLC6A3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
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G |
SMIM20 |
small integral membrane protein 20 |
increases expression |
ISO |
Oleic Acid results in increased expression of SMIM20 mRNA |
CTD |
PMID:30524225 |
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NCBI chr 4:25,914,220...25,929,812
Ensembl chr 4:25,861,830...25,929,813
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G |
SNAP23 |
synaptosome associated protein 23 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA |
CTD |
PMID:30547786 |
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NCBI chr15:42,491,129...42,533,058
Ensembl chr15:42,491,233...42,545,356
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G |
SNHG14 |
small nucleolar RNA host gene 14 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SNHG14 mRNA; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] |
CTD |
PMID:37009739 |
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NCBI chr15:24,823,608...25,419,462
Ensembl chr15:24,978,583...25,420,336
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G |
SOCS1 |
suppressor of cytokine signaling 1 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
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G |
SOCS2 |
suppressor of cytokine signaling 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487
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G |
SOCS3 |
suppressor of cytokine signaling 3 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions decreases secretion decreases expression |
EXP |
Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in decreased secretion of SOD1 protein]; gastrodin inhibits the reaction [Oleic Acid results in decreased expression of SOD1 mRNA] |
CTD |
PMID:26634892 PMID:27996362 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
increases expression multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of SOD2 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA |
CTD |
PMID:24349266 PMID:30547786 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SQSTM1 |
sequestosome 1 |
multiple interactions increases expression |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein]; necrostatin-1 inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:36273635 PMID:36905866 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Oleic Acid results in increased expression of SREBF1 mRNA Oleic Acid results in increased expression of SREBF1 mRNA; Oleic Acid results in increased expression of SREBF1 protein [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; sophocarpine inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Dibutyl Phthalate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of SREBF1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 protein] Oleic Acid results in decreased expression of SREBF1 mRNA; Oleic Acid results in decreased expression of SREBF1 protein |
CTD |
PMID:15949695 PMID:23395669 PMID:23603006 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30165350 PMID:30611723 PMID:31730885 PMID:33508418 PMID:36347319 PMID:36529352 PMID:36905866 PMID:38092172 PMID:38103844 More...
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NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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G |
TBXA2R |
thromboxane A2 receptor |
multiple interactions |
ISO |
Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA] |
CTD |
PMID:11263294 |
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NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
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G |
TECR |
trans-2,3-enoyl-CoA reductase |
multiple interactions |
EXP |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of TECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:14,527,726...14,565,980
Ensembl chr19:14,517,085...14,565,980
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G |
TFAM |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
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G |
TFRC |
transferrin receptor |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] |
CTD |
PMID:32976958 |
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NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions increases expression |
EXP |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TGFB1 protein] |
CTD |
PMID:32918399 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGFB2 |
transforming growth factor beta 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
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G |
THRSP |
thyroid hormone responsive |
multiple interactions decreases expression |
EXP |
Bezafibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] |
CTD |
PMID:24534255 |
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NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TIMP1 mRNA] |
CTD |
PMID:26187275 PMID:30547786 PMID:32918399 |
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NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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G |
TNF |
tumor necrosis factor |
decreases response to substance increases expression multiple interactions |
EXP ISO |
Oleic Acid results in decreased susceptibility to TNF protein Oleic Acid results in increased expression of TNF mRNA; Oleic Acid results in increased expression of TNF protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF protein] |
CTD |
PMID:22683933 PMID:23348005 PMID:26190035 PMID:26634892 PMID:30547786 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP2 |
TNF alpha induced protein 2 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:103,121,469...103,137,439
Ensembl chr14:103,121,476...103,137,439
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G |
TP53 |
tumor protein p53 |
multiple interactions |
EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA |
CTD |
PMID:32369900 |
|
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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G |
TUBB2A |
tubulin beta 2A class IIa |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544
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G |
TUFM |
Tu translation elongation factor, mitochondrial |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA |
CTD |
PMID:30547786 |
|
NCBI chr16:28,842,411...28,846,348
Ensembl chr16:28,842,411...28,846,348
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G |
UCP2 |
uncoupling protein 2 |
increases expression multiple interactions decreases expression |
ISO |
Oleic Acid results in increased expression of UCP2 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein] Oleic Acid results in decreased expression of UCP2 mRNA |
CTD |
PMID:11341955 PMID:12588052 PMID:24349266 PMID:25048947 PMID:26854922 |
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NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843
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G |
UCP3 |
uncoupling protein 3 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of UCP3 mRNA Oleic Acid inhibits the reaction [troglitazone results in decreased expression of UCP3 mRNA] |
CTD |
PMID:11056218 PMID:12630940 |
|
NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
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G |
UGCG |
UDP-glucose ceramide glucosyltransferase |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369
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G |
VAMP4 |
vesicle associated membrane protein 4 |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VAMP4 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:171,700,160...171,742,065
Ensembl chr 1:171,700,160...171,742,074
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G |
VCAN |
versican |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VCAN mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
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G |
VNN1 |
vanin 1 |
multiple interactions |
EXP |
Oleic Acid promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of VNN1 mRNA] |
CTD |
PMID:31340670 |
|
NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions |
EXP ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
|
NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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G |
YAP1 |
Yes1 associated transcriptional regulator |
affects localization |
EXP |
Oleic Acid affects the localization of YAP1 protein |
CTD |
PMID:37117602 |
|
NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424
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G |
LIPC |
lipase C, hepatic type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
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G |
LIPG |
lipase G, endothelial type |
decreases abundance multiple interactions |
ISO |
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
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G |
LIPC |
lipase C, hepatic type |
decreases abundance |
ISO |
LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
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G |
LIPG |
lipase G, endothelial type |
decreases abundance |
ISO |
LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
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G |
FABP1 |
fatty acid binding protein 1 |
affects abundance |
ISO |
FABP1 protein affects the abundance of 2-oleoylglycerol |
CTD |
PMID:29414765 |
|
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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G |
MGLL |
monoglyceride lipase |
increases degradation multiple interactions |
ISO |
MGLL protein results in increased degradation of 2-oleoylglycerol Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol] |
CTD |
PMID:19515121 |
|
NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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G |
PAFAH1B1 |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
multiple interactions increases expression |
ISO |
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein] |
CTD |
PMID:1354728 PMID:2743081 PMID:8738301 |
|
NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,183...2,685,615
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G |
LIPC |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
|
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G |
LIPG |
lipase G, endothelial type |
multiple interactions increases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate LIPG gene mutant form results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
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G |
ABCG8 |
ATP binding cassette subfamily G member 8 |
affects expression |
ISO |
Corn Oil affects the expression of ABCG8 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988
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G |
ACACA |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Corn Oil results in increased expression of ACACA mRNA |
CTD |
PMID:1973097 |
|
NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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G |
ACLY |
ATP citrate lyase |
affects expression |
ISO |
Corn Oil affects the expression of ACLY mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
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G |
ACOT2 |
acyl-CoA thioesterase 2 |
affects expression |
ISO |
Corn Oil affects the expression of ACOT2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] |
CTD |
PMID:29165388 |
|
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
ALDH1A1 |
aldehyde dehydrogenase 1 family member A1 |
affects expression |
ISO |
Corn Oil affects the expression of ALDH1A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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G |
ANGPTL4 |
angiopoietin like 4 |
affects expression |
ISO |
Corn Oil affects the expression of ANGPTL4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
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G |
AREG |
amphiregulin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
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G |
BAD |
BCL2 associated agonist of cell death |
increases expression |
ISO |
Corn Oil results in increased expression of BAD mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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G |
BDKRB1 |
bradykinin receptor B1 |
multiple interactions |
ISO |
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
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G |
BHLHE40 |
basic helix-loop-helix family member e40 |
affects expression |
ISO |
Corn Oil affects the expression of BHLHE40 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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G |
BHMT |
betaine--homocysteine S-methyltransferase |
affects expression |
ISO |
Corn Oil affects the expression of BHMT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
|
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G |
BIRC3 |
baculoviral IAP repeat containing 3 |
increases expression |
ISO |
Corn Oil results in increased expression of BIRC3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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G |
BMP1 |
bone morphogenetic protein 1 |
affects expression |
ISO |
Corn Oil affects the expression of BMP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:22,165,372...22,212,326
Ensembl chr 8:22,165,140...22,212,326
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G |
BMP2 |
bone morphogenetic protein 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
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G |
CA6 |
carbonic anhydrase 6 |
increases expression |
ISO |
Corn Oil results in increased expression of CAR6 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:8,945,868...8,975,092
Ensembl chr 1:8,945,867...8,975,092
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G |
CADM1 |
cell adhesion molecule 1 |
affects expression |
ISO |
Corn Oil affects the expression of CADM1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
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G |
CALCA |
calcitonin related polypeptide alpha |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA |
CTD |
PMID:32186404 |
|
NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
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G |
CARD9 |
caspase recruitment domain family member 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CARD9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681
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G |
CAT |
catalase |
decreases expression multiple interactions |
ISO |
Corn Oil results in decreased expression of CAT protein [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein |
CTD |
PMID:36432690 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV3 |
caveolin 3 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CAV3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
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G |
CCL3 |
C-C motif chemokine ligand 3 |
decreases expression increases expression |
ISO |
Corn Oil results in decreased expression of CCL3 mRNA Corn Oil results in increased expression of CCL3 mRNA |
CTD |
PMID:22760963 PMID:23409006 |
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NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCND1 |
cyclin D1 |
affects expression |
ISO |
Corn Oil affects the expression of CCND1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CD36 |
CD36 molecule (CD36 blood group) |
decreases expression |
ISO |
Corn Oil results in decreased expression of CD36 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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G |
CDHR1 |
cadherin related family member 1 |
increases expression |
ISO |
Corn Oil results in increased expression of CDHR1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr10:84,194,537...84,219,621
Ensembl chr10:84,194,537...84,219,621
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
increases expression affects expression |
ISO |
Corn Oil results in increased expression of CDKN1A mRNA Corn Oil affects the expression of CDKN1A mRNA |
CTD |
PMID:16360708 PMID:22760963 |
|
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CENPT |
centromere protein T |
increases expression |
ISO |
Corn Oil results in increased expression of CENPT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr16:67,828,157...67,847,693
Ensembl chr16:67,828,157...67,847,811
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G |
CFB |
complement factor B |
increases expression |
ISO |
Corn Oil results in increased expression of CFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
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G |
CLDN1 |
claudin 1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CLDN1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
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G |
CLDN9 |
claudin 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CLDN9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr16:3,012,923...3,014,505
Ensembl chr16:3,012,923...3,014,505
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G |
COX7A1 |
cytochrome c oxidase subunit 7A1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of COX7A1 mRNA |
CTD |
PMID:23409006 |
|
NCBI chr19:36,150,922...36,152,447
Ensembl chr19:36,150,922...36,152,449
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G |
COX8BP |
cytochrome c oxidase subunit 8B, pseudogene |
decreases expression |
ISO |
Corn Oil results in decreased expression of COX8B mRNA |
CTD |
PMID:23409006 |
|
NCBI chr11:253,417...256,972
Ensembl chr11:253,446...253,558
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G |
CPT1A |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions affects expression |
ISO |
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA |
CTD |
PMID:16360708 PMID:22760963 PMID:36432690 |
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NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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G |
CPT2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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G |
CROT |
carnitine O-octanoyltransferase |
affects expression multiple interactions |
ISO |
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA |
CTD |
PMID:16360708 PMID:36432690 |
|
NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794
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G |
CTSG |
cathepsin G |
increases expression |
ISO |
Corn Oil results in increased expression of CTSG mRNA |
CTD |
PMID:22760963 |
|
NCBI chr14:24,573,518...24,576,250
Ensembl chr14:24,573,518...24,576,250
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G |
CYP17A1 |
cytochrome P450 family 17 subfamily A member 1 |
affects expression |
ISO |
Corn Oil affects the expression of CYP17A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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G |
CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
affects expression |
ISO |
Corn Oil affects the expression of CYP7A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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G |
CYP8B1 |
cytochrome P450 family 8 subfamily B member 1 |
affects expression |
ISO |
Corn Oil affects the expression of CYP8B1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898
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G |
EPHX2 |
epoxide hydrolase 2 |
affects expression |
ISO |
Corn Oil affects the expression of EPHX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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G |
ETS1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
ISO |
Corn Oil results in decreased expression of ETS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558
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G |
FABP1 |
fatty acid binding protein 1 |
multiple interactions |
ISO |
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA |
CTD |
PMID:15016835 |
|
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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G |
FABP2 |
fatty acid binding protein 2 |
affects expression |
ISO |
Corn Oil affects the expression of FABP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
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G |
FABP7 |
fatty acid binding protein 7 |
affects expression |
ISO |
Corn Oil affects the expression of FABP7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074
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G |
FASN |
fatty acid synthase |
affects expression |
ISO |
Corn Oil affects the expression of FASN mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FCGRT |
Fc gamma receptor and transporter |
decreases expression |
ISO |
Corn Oil results in decreased expression of FCGRT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:49,512,661...49,526,428
Ensembl chr19:49,506,816...49,526,428
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G |
FGB |
fibrinogen beta chain |
affects expression |
ISO |
Corn Oil affects the expression of FGB mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
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G |
FGF21 |
fibroblast growth factor 21 |
affects expression |
ISO |
Corn Oil affects the expression of FGF21 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
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|
G |
FST |
follistatin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134
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|
G |
G0S2 |
G0/G1 switch 2 |
affects expression |
ISO |
Corn Oil affects the expression of G0S2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
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|
G |
GADD45A |
growth arrest and DNA damage inducible alpha |
affects expression |
ISO |
Corn Oil affects the expression of GADD45A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
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|
G |
GAL |
galanin and GMAP prepropeptide |
increases expression |
ISO |
Corn Oil results in increased expression of GAL mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
|
|
G |
GCK |
glucokinase |
affects expression |
ISO |
Corn Oil affects the expression of GCK mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
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|
G |
GJD2 |
gap junction protein delta 2 |
increases expression |
ISO |
Corn Oil results in increased expression of GJD2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr15:34,751,032...34,754,998
Ensembl chr15:34,751,032...34,754,998
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G |
GOT1 |
glutamic-oxaloacetic transaminase 1 |
affects expression |
ISO |
Corn Oil affects the expression of GOT1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
|
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G |
GOT2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
ISO |
Corn Oil results in decreased expression of GOT2 mRNA |
CTD |
PMID:34987138 |
|
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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G |
GPD2 |
glycerol-3-phosphate dehydrogenase 2 |
affects expression |
ISO |
Corn Oil affects the expression of GPD2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735
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|
G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] |
CTD |
PMID:29479035 |
|
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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|
G |
H2AC25 |
H2A clustered histone 25 |
affects expression |
ISO |
Corn Oil affects the expression of H2A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:228,457,364...228,457,873
Ensembl chr 1:228,434,777...228,457,873
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|
G |
HAL |
histidine ammonia-lyase |
affects expression |
ISO |
Corn Oil affects the expression of HAL mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
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|
G |
HAMP |
hepcidin antimicrobial peptide |
affects expression |
ISO |
Corn Oil affects the expression of HAMP mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
|
|
G |
HLA-A |
major histocompatibility complex, class I, A |
increases expression |
ISO |
Corn Oil results in increased expression of RT1-CE16 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
|
|
G |
HLA-DQB1 |
major histocompatibility complex, class II, DQ beta 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RT1-BB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
|
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G |
HLA-F |
major histocompatibility complex, class I, F |
increases expression |
ISO |
Corn Oil results in increased expression of RT1-CE5 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528
|
|
G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
affects expression |
ISO |
Corn Oil affects the expression of HMGCR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
|
|
G |
HOXA11 |
homeobox A11 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
|
|
G |
HP |
haptoglobin |
increases expression |
ISO |
Corn Oil results in increased expression of HP mRNA |
CTD |
PMID:22760963 |
|
NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
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|
G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Corn Oil results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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G |
IDI1 |
isopentenyl-diphosphate delta isomerase 1 |
affects expression |
ISO |
Corn Oil affects the expression of IDI1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
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G |
IGF2BP2 |
insulin like growth factor 2 mRNA binding protein 2 |
affects expression increases expression |
ISO |
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:185,643,130...185,825,042
Ensembl chr 3:185,643,130...185,825,042
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G |
IGFBP1 |
insulin like growth factor binding protein 1 |
affects expression |
ISO |
Corn Oil affects the expression of IGFBP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
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|
G |
IHH |
Indian hedgehog signaling molecule |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
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|
G |
IL12B |
interleukin 12B |
increases secretion |
ISO |
Corn Oil results in increased secretion of IL12B protein |
CTD |
PMID:33263755 |
|
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
IL18 |
interleukin 18 |
increases expression |
ISO |
Corn Oil results in increased expression of IL18 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1A |
interleukin 1 alpha |
increases secretion |
ISO |
Corn Oil results in increased secretion of IL1A protein |
CTD |
PMID:33263755 |
|
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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G |
IL1B |
interleukin 1 beta |
increases secretion |
ISO |
Corn Oil results in increased secretion of IL1B protein |
CTD |
PMID:33263755 |
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL1RN |
interleukin 1 receptor antagonist |
increases expression |
ISO |
Corn Oil results in increased expression of IL1RN mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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G |
IL4 |
interleukin 4 |
increases expression increases secretion decreases expression |
ISO |
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA |
CTD |
PMID:23409006 PMID:33263755 |
|
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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G |
IL6R |
interleukin 6 receptor |
increases expression |
ISO |
Corn Oil results in increased expression of IL6R mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
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G |
IL9 |
interleukin 9 |
increases secretion |
ISO |
Corn Oil results in increased secretion of IL9 protein |
CTD |
PMID:33263755 |
|
NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841
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G |
INHBE |
inhibin subunit beta E |
affects expression |
ISO |
Corn Oil affects the expression of INHBE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280
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|
G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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|
G |
IRAK1 |
interleukin 1 receptor associated kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of IRAK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:154,010,507...154,019,902
Ensembl chr X:154,010,506...154,019,902
|
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G |
IRF5 |
interferon regulatory factor 5 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF5 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
|
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G |
IRF7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
|
|
G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Corn Oil results in increased expression of JUN mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
|
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G |
KLF2 |
KLF transcription factor 2 |
affects expression |
ISO |
Corn Oil affects the expression of KLF2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
|
|
G |
LCAT |
lecithin-cholesterol acyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA |
CTD |
PMID:36432690 |
|
NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
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G |
LCN2 |
lipocalin 2 |
increases expression |
ISO |
Corn Oil results in increased expression of LCN2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
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G |
LEP |
leptin |
multiple interactions |
ISO |
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein] |
CTD |
PMID:29165388 |
|
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LGALS1 |
galectin 1 |
increases expression |
ISO |
Corn Oil results in increased expression of LGALS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
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G |
LOX |
lysyl oxidase |
multiple interactions |
ISO |
Corn Oil results in increased activity of and results in increased cleavage of LOX protein |
CTD |
PMID:26240151 |
|
NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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|
G |
LY75 |
lymphocyte antigen 75 |
increases expression |
ISO |
Corn Oil results in increased expression of LY75 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:159,803,355...159,904,756
Ensembl chr 2:159,803,355...159,904,756
|
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G |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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G |
MAP2K3 |
mitogen-activated protein kinase kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232
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G |
MAP2K6 |
mitogen-activated protein kinase kinase 6 |
affects expression |
ISO |
Corn Oil affects the expression of MAP2K6 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865
|
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G |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP3K7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
|
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G |
MAPK14 |
mitogen-activated protein kinase 14 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK14 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MDM2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
Corn Oil results in decreased expression of MDM2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
|
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G |
MGMT |
O-6-methylguanine-DNA methyltransferase |
increases expression |
ISO |
Corn Oil results in increased expression of MGMT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
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G |
MGST2 |
microsomal glutathione S-transferase 2 |
increases expression |
ISO |
Corn Oil results in increased expression of MGST2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:139,665,819...139,754,618
Ensembl chr 4:139,665,768...139,740,745
|
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G |
MLYCD |
malonyl-CoA decarboxylase |
decreases expression |
ISO |
Corn Oil results in decreased expression of MLYCD mRNA |
CTD |
PMID:22760963 |
|
NCBI chr16:83,899,115...83,927,031
Ensembl chr16:83,899,115...83,951,445
|
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G |
MSMO1 |
methylsterol monooxygenase 1 |
affects expression |
ISO |
Corn Oil affects the expression of MSMO1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
|
|
G |
MTR |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
|
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G |
MX2 |
MX dynamin like GTPase 2 |
affects expression |
ISO |
Corn Oil affects the expression of MX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
|
|
G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
increases expression |
ISO |
Corn Oil results in increased expression of MYD88 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
|
|
G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
decreases activity |
ISO |
Corn Oil results in decreased activity of NFE2L2 protein |
CTD |
PMID:30203046 |
|
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
|
|
G |
NFKBIA |
NFKB inhibitor alpha |
increases expression |
ISO |
Corn Oil results in increased expression of NFKBIA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
|
|
G |
NLRC4 |
NLR family CARD domain containing 4 |
increases expression |
ISO |
Corn Oil results in increased expression of NLRC4 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 2:32,224,449...32,265,743
Ensembl chr 2:32,224,453...32,265,732
|
|
G |
NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
affects expression |
ISO |
Corn Oil affects the expression of NR1H4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
|
|
G |
NR4A2 |
nuclear receptor subfamily 4 group A member 2 |
increases expression |
ISO |
Corn Oil results in increased expression of NR4A2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348
|
|
G |
NSMCE3 |
NSE3 homolog, SMC5-SMC6 complex component |
affects expression |
ISO |
Corn Oil affects the expression of NSMCE3 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:29,264,989...29,269,822
Ensembl chr15:29,264,989...29,269,822
|
|
G |
OAT |
ornithine aminotransferase |
affects expression |
ISO |
Corn Oil affects the expression of OAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976
|
|
G |
OSGIN1 |
oxidative stress induced growth inhibitor 1 |
affects expression |
ISO |
Corn Oil affects the expression of OSGIN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
|
|
G |
P2RX5 |
purinergic receptor P2X 5 |
affects expression |
ISO |
Corn Oil affects the expression of P2RX5 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240
|
|
G |
PAX8 |
paired box 8 |
affects expression |
ISO |
Corn Oil affects the expression of PAX8 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
|
|
G |
PDGFA |
platelet derived growth factor subunit A |
affects expression |
ISO |
Corn Oil affects the expression of PDGFA mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296
|
|
G |
PDGFRB |
platelet derived growth factor receptor beta |
increases expression |
ISO |
Corn Oil results in increased expression of PDGFRB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
|
|
G |
PDLIM1 |
PDZ and LIM domain 1 |
affects expression |
ISO |
Corn Oil affects the expression of PDLIM1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:95,237,572...95,291,003
Ensembl chr10:95,237,572...95,291,012
|
|
G |
PDLIM2 |
PDZ and LIM domain 2 |
affects expression |
ISO |
Corn Oil affects the expression of PDLIM2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:22,578,741...22,598,026
Ensembl chr 8:22,578,279...22,598,025
|
|
G |
PGF |
placental growth factor |
increases expression |
ISO |
Corn Oil results in increased expression of PGF mRNA |
CTD |
PMID:22760963 |
|
NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
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G |
PGRMC2 |
progesterone receptor membrane component 2 |
affects expression |
ISO |
Corn Oil affects the expression of PGRMC2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:128,269,242...128,287,813
Ensembl chr 4:128,269,237...128,288,829
|
|
G |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
increases expression |
ISO |
Corn Oil results in increased expression of PIK3CA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
|
|
G |
PLIN2 |
perilipin 2 |
affects expression |
ISO |
Corn Oil affects the expression of PLIN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
|
|
G |
PRLR |
prolactin receptor |
affects expression |
ISO |
Corn Oil affects the expression of PRLR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
|
|
G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
|
|
G |
PTPRF |
protein tyrosine phosphatase receptor type F |
affects expression |
ISO |
Corn Oil affects the expression of PTPRF mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666
|
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G |
PYCARD |
PYD and CARD domain containing |
increases expression |
ISO |
Corn Oil results in increased expression of PYCARD mRNA |
CTD |
PMID:33263755 |
|
NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
|
|
G |
RAC1 |
Rac family small GTPase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RAC1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
|
|
G |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187
|
|
G |
RIPK2 |
receptor interacting serine/threonine kinase 2 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
|
|
G |
S100A8 |
S100 calcium binding protein A8 |
increases expression |
ISO |
Corn Oil results in increased expression of S100A8 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
|
|
G |
S100A9 |
S100 calcium binding protein A9 |
increases expression |
ISO |
Corn Oil results in increased expression of S100A9 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
|
|
G |
SCD |
stearoyl-CoA desaturase |
affects expression |
ISO |
Corn Oil affects the expression of SCD1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
|
|
G |
SCN1B |
sodium voltage-gated channel beta subunit 1 |
affects expression |
ISO |
Corn Oil affects the expression of SCN1B mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
|
|
G |
SDS |
serine dehydratase |
affects expression |
ISO |
Corn Oil affects the expression of SDS mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301
|
|
G |
SFRP2 |
secreted frizzled related protein 2 |
decreases expression |
ISO |
Corn Oil results in decreased expression of SFRP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
|
|
G |
SLC25A20 |
solute carrier family 25 member 20 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904
|
|
G |
SLC25A25 |
solute carrier family 25 member 25 |
affects expression |
ISO |
Corn Oil affects the expression of SLC25A25 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 9:128,068,232...128,109,245
Ensembl chr 9:128,068,201...128,109,245
|
|
G |
SOD1 |
superoxide dismutase 1 |
multiple interactions decreases activity |
ISO |
[Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein] |
CTD |
PMID:17194920 |
|
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
|
|
G |
SPARC |
secreted protein acidic and cysteine rich |
increases expression |
ISO |
Corn Oil results in increased expression of SPARC mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
|
|
G |
SQLE |
squalene epoxidase |
affects expression |
ISO |
Corn Oil affects the expression of SQLE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
|
|
G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
affects expression |
ISO |
Corn Oil affects the expression of SREBF1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
|
|
G |
SSTR3 |
somatostatin receptor 3 |
decreases expression |
ISO |
Corn Oil results in decreased expression of SSTR3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr22:37,204,237...37,220,548
Ensembl chr22:37,204,237...37,212,477
|
|
G |
SUGT1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
increases expression |
ISO |
Corn Oil results in increased expression of SUGT1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909
|
|
G |
SYK |
spleen associated tyrosine kinase |
increases expression |
ISO |
Corn Oil results in increased expression of SYK mRNA |
CTD |
PMID:23409006 |
|
NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
|
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G |
TAC1 |
tachykinin precursor 1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of TAC1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
|
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G |
TAT |
tyrosine aminotransferase |
affects expression |
ISO |
Corn Oil affects the expression of TAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
|
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G |
TBC1D14 |
TBC1 domain family member 14 |
affects expression |
ISO |
Corn Oil affects the expression of TBC1D14 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:6,909,466...7,033,114
Ensembl chr 4:6,909,242...7,033,118
|
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G |
TGFA |
transforming growth factor alpha |
decreases expression |
ISO |
Corn Oil results in decreased expression of TGFA mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
|
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G |
TICAM1 |
TIR domain containing adaptor molecule 1 |
increases expression |
ISO |
Corn Oil results in increased expression of TICAM1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
|
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G |
TJP2 |
tight junction protein 2 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615
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G |
TJP3 |
tight junction protein 3 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr19:3,708,384...3,750,813
Ensembl chr19:3,708,362...3,750,813
|
|
G |
TNFRSF1A |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Corn Oil results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:33263755 |
|
NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
|
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G |
TOLLIP |
toll interacting protein |
increases expression |
ISO |
Corn Oil results in increased expression of TOLLIP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:1,274,371...1,309,632
Ensembl chr11:1,274,371...1,309,654
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G |
TPCN2 |
two pore segment channel 2 |
affects expression |
ISO |
Corn Oil affects the expression of TPCN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
|
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G |
TPT1 |
tumor protein, translationally-controlled 1 |
increases expression |
ISO |
Corn Oil results in increased expression of TPT1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284
|
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G |
VEGFB |
vascular endothelial growth factor B |
decreases expression |
ISO |
Corn Oil results in decreased expression of VEGFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
|
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G |
VNN1 |
vanin 1 |
affects expression |
ISO |
Corn Oil affects the expression of VNN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
|
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G |
XIAP |
X-linked inhibitor of apoptosis |
decreases expression |
ISO |
Corn Oil results in decreased expression of XIAP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:123,859,708...123,913,972
Ensembl chr X:123,859,712...123,913,972
|
|
G |
XPNPEP2 |
X-prolyl aminopeptidase 2 |
affects expression |
ISO |
Corn Oil affects the expression of XPNPEP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr X:129,738,979...129,769,536
Ensembl chr X:129,738,949...129,769,536
|
|
G |
ZDHHC23 |
zinc finger DHHC-type palmitoyltransferase 23 |
affects expression |
ISO |
Corn Oil affects the expression of ZDHHC23 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:113,947,901...113,979,508
Ensembl chr 3:113,947,901...113,965,401
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|
G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of AHR protein |
CTD |
PMID:27633901 |
|
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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G |
ESR1 |
estrogen receptor 1 |
multiple interactions |
EXP |
methyl oleate binds to and results in increased activity of ESR1 protein |
CTD |
PMID:27633901 |
|
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
|
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
methyl oleate binds to and results in increased activity of PPARG protein |
CTD |
PMID:27633901 |
|
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
|
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G |
CNR1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
N-oleoyldopamine binds to and results in increased activity of CNR1 protein |
CTD |
PMID:12569099 |
|
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
|
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
|
|
G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
EXP |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
|
|
G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
multiple interactions increases activity |
ISO EXP |
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]] N-oleoyldopamine results in increased activity of TRPV1 protein 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [N-oleoyldopamine results in increased activity of TRPV1 protein] |
CTD |
PMID:12569099 PMID:15615864 |
|
NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
|
|
|
G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
increases export |
EXP |
ABCB1 protein results in increased export of N-oleoylethanolamine |
CTD |
PMID:30102254 |
|
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
|
|
G |
PPARA |
peroxisome proliferator activated receptor alpha |
increases response to substance multiple interactions |
ISO EXP |
PPARA results in increased susceptibility to N-oleoylethanolamine N-oleoylethanolamine binds to and results in increased activity of PPARA protein |
CTD |
PMID:17906680 |
|
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
|
|
G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
N-oleoylethanolamine results in decreased expression of PTGS2 protein |
CTD |
PMID:17906680 |
|
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
|
|
|
G |
CNR1 |
cannabinoid receptor 1 |
affects binding |
EXP |
ricinoleic acid analog binds to CNR1 protein |
CTD |
PMID:16406364 |
|
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
|
|
G |
CNR2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
ricinoleic acid analog binds to and affects the activity of CNR2 protein |
CTD |
PMID:16406364 |
|
NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
|
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G |
IL4 |
interleukin 4 |
multiple interactions |
EXP |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
|
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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G |
PTGDS |
prostaglandin D2 synthase |
affects binding |
EXP |
ricinoleic acid binds to PTGDS protein |
CTD |
PMID:26456343 |
|
NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
|
|
G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
multiple interactions |
EXP |
ricinoleic acid analog binds to and affects the activity of TRPV1 protein |
CTD |
PMID:16406364 |
|
NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
|
|
G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
|
NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
|
|
|
G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
affects expression |
ISO |
Soybean Oil affects the expression of ABCB11 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
|
|
G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
affects expression |
ISO |
Soybean Oil affects the expression of ABCB4 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
|
|
G |
ABCC1 |
ATP binding cassette subfamily C member 1 (ABCC1 blood group) |
affects expression |
ISO |
Soybean Oil affects the expression of ABCC1 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
|
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
affects expression |
ISO |
Soybean Oil affects the expression of ABCC2 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
|
|
G |
ABCC5 |
ATP binding cassette subfamily C member 5 |
affects expression |
ISO |
Soybean Oil affects the expression of ABCC5 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939
|
|
G |
ABCC6 |
ATP binding cassette subfamily C member 6 |
affects expression |
ISO |
Soybean Oil affects the expression of ABCC6 mRNA |
CTD |
PMID:15770074 |
|
NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
|
|
G |
ACAT1 |
acetyl-CoA acetyltransferase 1 |
decreases activity |
ISO |
Soybean Oil results in decreased activity of ACAT1 protein |
CTD |
PMID:12559476 |
|
NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
increases expression |
ISO |
Soybean Oil results in increased expression of BCL2 protein |
CTD |
PMID:15309441 |
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
CAT |
catalase |
increases activity |
ISO |
Soybean Oil results in increased activity of CAT protein |
CTD |
PMID:12781854 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
|
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G |
CCND1 |
cyclin D1 |
increases expression |
ISO |
Soybean Oil results in increased expression of CCND1 mRNA |
CTD |
PMID:21088903 |
|
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
|
|
G |
CYP4A22 |
cytochrome P450 family 4 subfamily A member 22 |
affects expression |
ISO |
Soybean Oil affects the expression of CYP4A1 mRNA |
CTD |
PMID:16079505 |
|
NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727
|
|
G |
CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
increases activity |
ISO |
Soybean Oil results in increased activity of CYP7A1 protein |
CTD |
PMID:12559476 |
|
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
|
|
G |
GSTP1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] |
CTD |
PMID:11600134 |
|
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
|
|
G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases activity |
ISO |
Soybean Oil results in increased activity of HMGCR protein |
CTD |
PMID:12559476 |
|
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
|
|
G |
IL12B |
interleukin 12B |
decreases expression |
ISO |
Soybean Oil results in decreased expression of IL12B mRNA |
CTD |
PMID:10065739 |
|
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
SLC22A1 |
solute carrier family 22 member 1 |
affects expression |
ISO |
Soybean Oil affects the expression of SLC22A1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
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G |
SLC22A7 |
solute carrier family 22 member 7 |
affects expression |
ISO |
Soybean Oil affects the expression of SLC22A7 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538
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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCA1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCG5 |
ATP binding cassette subfamily G member 5 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG5 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
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G |
ABCG8 |
ATP binding cassette subfamily G member 8 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG8 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988
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G |
ACACA |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] |
CTD |
PMID:15066988 |
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NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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G |
APOA4 |
apolipoprotein A4 |
multiple interactions |
ISO |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in increased expression of APOA4 protein |
CTD |
PMID:6631239 |
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NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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G |
APOE |
apolipoprotein E |
multiple interactions |
ISO |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in decreased expression of APOE protein |
CTD |
PMID:6631239 |
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NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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G |
APP |
amyloid beta precursor protein |
multiple interactions |
ISO |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein alternative form]; Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] |
CTD |
PMID:28734741 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
CAT |
catalase |
multiple interactions |
ISO |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of CAT mRNA] |
CTD |
PMID:28734741 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CYP27A1 |
cytochrome P450 family 27 subfamily A member 1 |
decreases expression |
ISO |
Triolein results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293
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G |
FASN |
fatty acid synthase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] |
CTD |
PMID:15066988 |
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Triolein results in increased expression of HMGCR mRNA |
CTD |
PMID:18356535 |
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NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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G |
MTTP |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Triolein results in increased expression of MTTP mRNA |
CTD |
PMID:18356535 |
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NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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G |
NPC1L1 |
NPC1 like intracellular cholesterol transporter 1 |
decreases expression |
ISO |
Triolein results in decreased expression of NPC1L1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 7:44,512,535...44,541,330
Ensembl chr 7:44,512,535...44,541,330
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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