NRF1 Human (+)-schisandrin B multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NRF1 mRNA] CTD PMID:31150632 NRF1 Human (R)-noradrenaline multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Norepinephrine] results in decreased expression of NRF1 mRNA CTD PMID:16954335 NRF1 Human 1-chloro-2,4-dinitrobenzene decreases expression ISO Nrf1 (Mus musculus) 6480464 Dinitrochlorobenzene results in decreased expression of NRF1 mRNA CTD PMID:28219650 NRF1 Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Nrf1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:21856379 NRF1 Human 17beta-estradiol multiple interactions EXP 6480464 ESR1 protein alternative form inhibits the reaction [Estradiol results in increased expression of NRF1 mRNA] more ... CTD PMID:20302909 and PMID:22105178 NRF1 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of NRF1 mRNA CTD PMID:20302909 more ... NRF1 Human 17beta-estradiol multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Norepinephrine] results in decreased expression of NRF1 mRNA CTD PMID:16954335 NRF1 Human 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 1H-(1 more ... CTD PMID:17179207 NRF1 Human 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:24041027 NRF1 Human 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 MIR128-1 promotes the reaction [2 more ... CTD PMID:36269211 NRF1 Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:36269211 NRF1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Nrf1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of NRF1 mRNA CTD PMID:21570461 and PMID:24058054 NRF1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of NRF1 mRNA CTD PMID:21296121 NRF1 Human 2,3-bis(4-hydroxyphenyl)propionitrile increases expression EXP 6480464 2 and 3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of NRF1 mRNA CTD PMID:22105178 NRF1 Human 2,4-dinitrophenol increases expression ISO Nrf1 (Mus musculus) 6480464 2 and 4-Dinitrophenol results in increased expression of NRF1 mRNA CTD PMID:11784294 NRF1 Human 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine affects expression ISO Nrf1 (Rattus norvegicus) 6480464 Puromycin Aminonucleoside affects the expression of NRF1 mRNA CTD PMID:16609681 NRF1 Human 3,4-methylenedioxymethamphetamine increases expression ISO Nrf1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NRF1 mRNA CTD PMID:20188158 NRF1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA more ... CTD PMID:29288687 and PMID:32417366 NRF1 Human 3-phenylprop-2-enal decreases expression ISO Nrf1 (Mus musculus) 6480464 cinnamaldehyde results in decreased expression of NRF1 mRNA CTD PMID:28219650 NRF1 Human 4,4'-diaminodiphenylmethane affects expression ISO Nrf1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane affects the expression of NRF1 mRNA CTD PMID:18648102 NRF1 Human 4-hydroxyphenyl retinamide increases expression ISO Nrf1 (Mus musculus) 6480464 Fenretinide results in increased expression of NRF1 mRNA CTD PMID:28973697 NRF1 Human 6-propyl-2-thiouracil decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of NRF1 mRNA CTD PMID:30047161 NRF1 Human 8-bromo-3',5'-cyclic GMP multiple interactions EXP 6480464 tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NRF1 mRNA] CTD PMID:24041027 NRF1 Human 8-bromo-3',5'-cyclic GMP increases expression EXP 6480464 8-bromocyclic GMP results in increased expression of NRF1 mRNA CTD PMID:24041027 NRF1 Human acadesine multiple interactions EXP 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of NRF1 protein] CTD PMID:28556920 NRF1 Human acadesine increases expression EXP 6480464 acadesine results in increased expression of NRF1 protein CTD PMID:28556920 NRF1 Human acetylsalicylic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of NRF1 protein] CTD PMID:37179038 NRF1 Human acrolein decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Acrolein results in decreased expression of NRF1 mRNA CTD PMID:35150775 NRF1 Human afimoxifene increases expression EXP 6480464 afimoxifene results in increased expression of NRF1 mRNA CTD PMID:22105178 NRF1 Human afimoxifene multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] and Vehicle Emissions inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] CTD PMID:22105178 NRF1 Human aflatoxin B1 increases expression ISO Nrf1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of NRF1 mRNA CTD PMID:19770486 NRF1 Human aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of NRF1 gene and Aflatoxin B1 results in increased methylation of NRF1 intron CTD PMID:27153756 and PMID:30157460 NRF1 Human AICA ribonucleotide multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] CTD PMID:20438809 NRF1 Human AICA ribonucleotide increases expression ISO Nrf1 (Rattus norvegicus) 6480464 AICA ribonucleotide results in increased expression of NRF1 mRNA CTD PMID:20438809 NRF1 Human all-trans-retinoic acid multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA]] CTD PMID:23331247 NRF1 Human alloxan multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Alloxan affects the reaction [imisopasem manganese results in increased expression of NRF1 protein] CTD PMID:28483572 NRF1 Human AM-251 multiple interactions ISO Nrf1 (Mus musculus) 6480464 AM 251 inhibits the reaction [Dietary Fats results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NRF1 Human amitrole decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Amitrole results in decreased expression of NRF1 mRNA CTD PMID:30047161 NRF1 Human ammonium chloride affects expression ISO Nrf1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of NRF1 mRNA CTD PMID:16483693 NRF1 Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of NRF1 mRNA CTD PMID:24449571 NRF1 Human arachidonyl-2'-chloroethylamide multiple interactions ISO Nrf1 (Mus musculus) 6480464 FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NRF1 Human arachidonyl-2'-chloroethylamide decreases expression ISO Nrf1 (Mus musculus) 6480464 arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA CTD PMID:26847930 NRF1 Human Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of NRF1 mRNA CTD PMID:16934159 NRF1 Human arsane increases expression EXP 6480464 Arsenic results in increased expression of NRF1 mRNA CTD PMID:21514422 NRF1 Human arsane affects methylation EXP 6480464 Arsenic affects the methylation of NRF1 gene CTD PMID:25304211 NRF1 Human arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of NRF1 mRNA CTD PMID:21514422 NRF1 Human arsenic atom affects methylation EXP 6480464 Arsenic affects the methylation of NRF1 gene CTD PMID:25304211 NRF1 Human arsenous acid affects methylation EXP 6480464 Arsenic Trioxide affects the methylation of NRF1 promoter CTD PMID:26046465 NRF1 Human atorvastatin calcium multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA] and Quercetin inhibits the reaction [Atorvastatin affects the expression of NRF1 mRNA] CTD PMID:21775390 NRF1 Human atorvastatin calcium affects expression ISO Nrf1 (Rattus norvegicus) 6480464 Atorvastatin affects the expression of NRF1 mRNA CTD PMID:21775390 NRF1 Human atorvastatin calcium increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Atorvastatin results in increased expression of NRF1 mRNA CTD PMID:21775390 NRF1 Human atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of NRF1 mRNA CTD PMID:27114639 NRF1 Human atrazine increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Atrazine results in increased expression of NRF1 mRNA CTD PMID:27114639 NRF1 Human benzo[a]pyrene multiple interactions ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to NRF1 promoter] and Benzo(a)pyrene promotes the reaction [NRF1 protein binds to GSTA1 gene] CTD PMID:11961136 and PMID:19654925 NRF1 Human benzo[a]pyrene multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of NRF1 mRNA] and Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of NRF1 protein] CTD PMID:32619457 NRF1 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of NRF1 5' UTR CTD PMID:27901495 NRF1 Human benzo[a]pyrene decreases methylation ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of NRF1 3' UTR and Benzo(a)pyrene results in decreased methylation of NRF1 exon CTD PMID:27901495 NRF1 Human benzo[a]pyrene affects expression ISO Nrf1 (Rattus norvegicus) 6480464 Benzo(a)pyrene affects the expression of NRF1 mRNA and Benzo(a)pyrene affects the expression of NRF1 protein CTD PMID:32619457 NRF1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of NRF1 mRNA and Benzo(a)pyrene results in decreased expression of NRF1 protein CTD PMID:21401886 and PMID:22865514 NRF1 Human benzo[a]pyrene multiple interactions EXP 6480464 NRF1 mutant form inhibits the reaction [Benzo(a)pyrene results in decreased expression of TFAM protein] and NRF1 mutant form promotes the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species] CTD PMID:21401886 NRF1 Human benzo[a]pyrene increases expression ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of NRF1 mRNA CTD PMID:22228805 NRF1 Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 NRF1 Human bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of NRF1 mRNA and Diethylhexyl Phthalate results in decreased expression of NRF1 protein CTD PMID:34822940 NRF1 Human bisphenol A increases expression ISO Nrf1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of NRF1 mRNA CTD PMID:25181051 more ... NRF1 Human bisphenol A decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of NRF1 mRNA CTD PMID:24105817 NRF1 Human Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:26520405 NRF1 Human Butylbenzyl phthalate decreases expression ISO Nrf1 (Mus musculus) 6480464 butylbenzyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:27923775 NRF1 Human cadmium atom increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Cadmium results in increased expression of NRF1 mRNA CTD PMID:25388156 NRF1 Human cadmium dichloride multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NRF1 mRNA] CTD PMID:36493885 NRF1 Human cadmium dichloride decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of NRF1 mRNA CTD PMID:36493885 NRF1 Human caffeine decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Caffeine results in decreased expression of NRF1 mRNA CTD PMID:20864626 NRF1 Human calcitriol increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Calcitriol results in increased expression of NRF1 protein CTD PMID:30194976 NRF1 Human calycosin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 7 more ... CTD PMID:36436616 NRF1 Human carbon monoxide multiple interactions ISO Nrf1 (Mus musculus) 6480464 AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein] and Carbon Monoxide promotes the reaction [NFE2L2 protein binds to NRF1 promoter] CTD PMID:18845810 NRF1 Human carbon monoxide increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Carbon Monoxide results in increased expression of NRF1 protein CTD PMID:17179207 NRF1 Human carbon monoxide increases localization ISO Nrf1 (Mus musculus) 6480464 Carbon Monoxide results in increased localization of NRF1 protein CTD PMID:18845810 NRF1 Human carbon monoxide multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 1H-(1 more ... CTD PMID:17179207 NRF1 Human carbon monoxide increases expression ISO Nrf1 (Mus musculus) 6480464 Carbon Monoxide results in increased expression of NRF1 mRNA CTD PMID:17179207 NRF1 Human CHIR 99021 decreases expression ISO Nrf1 (Mus musculus) 6480464 Chir 99021 results in decreased expression of NRF1 mRNA CTD PMID:29883716 NRF1 Human cisplatin decreases expression ISO Nrf1 (Mus musculus) 6480464 Cisplatin results in decreased expression of NRF1 mRNA and Cisplatin results in decreased expression of NRF1 protein CTD PMID:25270620 and PMID:37179038 NRF1 Human cisplatin multiple interactions ISO Nrf1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of NRF1 protein] CTD PMID:37179038 NRF1 Human copper atom increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of NRF1 protein CTD PMID:11694003 NRF1 Human copper atom decreases response to substance ISO Nrf1 (Mus musculus) 6480464 NRF1 gene results in decreased susceptibility to Copper CTD PMID:24462598 NRF1 Human copper atom multiple interactions ISO Nrf1 (Mus musculus) 6480464 NRF1 gene promotes the reaction [Copper results in increased expression of MT1 mRNA] CTD PMID:24462598 NRF1 Human copper(0) increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of NRF1 protein CTD PMID:11694003 NRF1 Human copper(0) decreases response to substance ISO Nrf1 (Mus musculus) 6480464 NRF1 gene results in decreased susceptibility to Copper CTD PMID:24462598 NRF1 Human copper(0) multiple interactions ISO Nrf1 (Mus musculus) 6480464 NRF1 gene promotes the reaction [Copper results in increased expression of MT1 mRNA] CTD PMID:24462598 NRF1 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of NRF1 mRNA CTD PMID:19549813 NRF1 Human cyclosporin A increases methylation EXP 6480464 Cyclosporine results in increased methylation of NRF1 promoter CTD PMID:27989131 NRF1 Human cyprodinil increases expression EXP 6480464 cyprodinil results in increased expression of NRF1 mRNA CTD PMID:33352482 NRF1 Human dexamethasone multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA more ... CTD PMID:29288687 and PMID:32417366 NRF1 Human Di-n-octyl phthalate decreases expression EXP 6480464 di-n-octyl phthalate results in decreased expression of NRF1 mRNA and di-n-octyl phthalate results in decreased expression of NRF1 protein CTD PMID:34822940 NRF1 Human diarsenic trioxide affects methylation EXP 6480464 Arsenic Trioxide affects the methylation of NRF1 promoter CTD PMID:26046465 NRF1 Human dioxygen multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein and genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein] CTD PMID:28477916 NRF1 Human dorsomorphin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] and dorsomorphin inhibits the reaction [Resveratrol results in increased expression of NRF1 mRNA] CTD PMID:20438809 NRF1 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of NRF1 protein CTD PMID:28456571 and PMID:29729358 NRF1 Human doxorubicin multiple interactions EXP 6480464 3-(2 more ... CTD PMID:28456571 and PMID:29729358 NRF1 Human elemental selenium multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA] CTD PMID:17936198 NRF1 Human elemental selenium increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Selenium results in increased expression of NRF1 mRNA CTD PMID:17936198 NRF1 Human enalapril increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Enalapril results in increased expression of NRF1 mRNA CTD PMID:18765277 NRF1 Human enniatin decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 enniatins results in decreased expression of NRF1 mRNA CTD PMID:27163883 NRF1 Human enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NRF1 protein CTD PMID:23301498 NRF1 Human Erythropoietin increases expression EXP 6480464 Erythropoietin results in increased expression of NRF1 protein CTD PMID:28456571 NRF1 Human Erythropoietin multiple interactions EXP 6480464 Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein] and SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]] CTD PMID:28456571 NRF1 Human ethidium increases expression EXP 6480464 Ethidium results in increased expression of NRF1 mRNA CTD PMID:22712077 NRF1 Human fenthion decreases expression ISO Nrf1 (Mus musculus) 6480464 Fenthion results in decreased expression of NRF1 mRNA CTD PMID:34813904 NRF1 Human fenvalerate increases expression ISO Nrf1 (Rattus norvegicus) 6480464 fenvalerate results in increased expression of NRF1 mRNA CTD PMID:30307764 NRF1 Human fludioxonil increases expression EXP 6480464 fludioxonil results in increased expression of NRF1 mRNA CTD PMID:23436777 NRF1 Human Flumetralin increases expression EXP 6480464 flumetralin results in increased expression of NRF1 mRNA CTD PMID:33352482 NRF1 Human formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of NRF1 mRNA CTD PMID:20655997 and PMID:23649840 NRF1 Human FR900359 decreases phosphorylation EXP 6480464 FR900359 results in decreased phosphorylation of NRF1 protein CTD PMID:37730182 NRF1 Human fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] more ... CTD PMID:22105178 NRF1 Human gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of NRF1 mRNA CTD PMID:23777605 NRF1 Human Genipin multiple interactions ISO Nrf1 (Mus musculus) 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein] CTD PMID:28477916 NRF1 Human Gingerenone A increases expression ISO Nrf1 (Mus musculus) 6480464 gingerenone A results in increased expression of NRF1 mRNA CTD PMID:28556482 NRF1 Human hemin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of NRF1 protein] CTD PMID:30040983 NRF1 Human hexadecanoic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA and FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NRF1 Human hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of NRF1 mRNA CTD PMID:23859249 NRF1 Human hydrogen peroxide affects response to substance EXP 6480464 NRF1 protein affects the susceptibility to Hydrogen Peroxide CTD PMID:21051700 NRF1 Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of NRF1 mRNA CTD PMID:20044591 NRF1 Human hydrogen peroxide multiple interactions EXP 6480464 resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRF1 mRNA] CTD PMID:23859249 NRF1 Human indinavir increases expression ISO Nrf1 (Mus musculus) 6480464 Indinavir results in increased expression of NRF1 mRNA CTD PMID:17926646 NRF1 Human isoniazide multiple interactions EXP 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of NRF1 protein] CTD PMID:28556920 NRF1 Human isoniazide decreases expression EXP 6480464 Isoniazid results in decreased expression of NRF1 protein CTD PMID:28556920 NRF1 Human lenvatinib affects expression ISO Nrf1 (Rattus norvegicus) 6480464 lenvatinib affects the expression of NRF1 mRNA CTD PMID:34019861 NRF1 Human Licarin A multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA CTD PMID:29288687 NRF1 Human losartan increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Losartan results in increased expression of NRF1 mRNA CTD PMID:18765277 NRF1 Human LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin results in increased expression of NRF1 mRNA] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonylchloro(glycinato)ruthenium(II) results in increased expression of NRF1 mRNA] CTD PMID:24041027 NRF1 Human LY294002 multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of NRF1 protein] CTD PMID:17179207 NRF1 Human manganese(II) chloride affects expression ISO Nrf1 (Rattus norvegicus) 6480464 manganese chloride affects the expression of NRF1 protein CTD PMID:30040983 NRF1 Human manganese(II) chloride multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of NRF1 protein] CTD PMID:30040983 NRF1 Human melatonin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of NRF1 protein] CTD PMID:26882442 NRF1 Human mepanipyrim increases expression EXP 6480464 mepanipyrim results in increased expression of NRF1 mRNA CTD PMID:33352482 NRF1 Human metformin increases expression ISO Nrf1 (Mus musculus) 6480464 Metformin results in increased expression of NRF1 mRNA CTD PMID:24428821 NRF1 Human metformin increases expression EXP 6480464 Metformin results in increased expression of NRF1 mRNA CTD PMID:16380484 NRF1 Human methamphetamine increases expression ISO Nrf1 (Mus musculus) 6480464 Methamphetamine results in increased expression of NRF1 mRNA CTD PMID:26307267 NRF1 Human methidathion decreases expression ISO Nrf1 (Mus musculus) 6480464 methidathion results in decreased expression of NRF1 mRNA CTD PMID:34813904 NRF1 Human methimazole decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Methimazole results in decreased expression of NRF1 mRNA CTD PMID:30047161 NRF1 Human methoxyacetic acid decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 methoxyacetic acid results in decreased expression of NRF1 mRNA CTD PMID:20864626 NRF1 Human methylglyoxal increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Pyruvaldehyde results in increased expression of NRF1 mRNA CTD PMID:23331247 NRF1 Human methylglyoxal multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] more ... CTD PMID:23331247 NRF1 Human methylmercury chloride decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 methylmercuric chloride results in decreased expression of NRF1 mRNA CTD PMID:20864626 NRF1 Human mitomycin C decreases expression ISO Nrf1 (Mus musculus) 6480464 Mitomycin results in decreased expression of NRF1 mRNA CTD PMID:25270620 NRF1 Human monascin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] and Tretinoin inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA]] CTD PMID:23331247 NRF1 Human mono(2-ethylhexyl) phthalate affects expression ISO Nrf1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate affects the expression of NRF1 mRNA CTD PMID:32522588 NRF1 Human Monobutylphthalate decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 monobutyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:20864626 NRF1 Human monocrotophos decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Monocrotophos results in decreased expression of NRF1 mRNA CTD PMID:35403558 NRF1 Human monocrotophos multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of NRF1 mRNA] CTD PMID:35403558 NRF1 Human N-acetyl-L-cysteine multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA] more ... CTD PMID:21775390 more ... NRF1 Human N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein CTD PMID:26141122 NRF1 Human N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 PPARGC1A protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA] and PPARGC1A protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein] CTD PMID:26141122 NRF1 Human nickel atom multiple interactions ISO Nrf1 (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of NRF1 mRNA CTD PMID:36794572 NRF1 Human nickel dichloride multiple interactions ISO Nrf1 (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of NRF1 mRNA CTD PMID:36794572 NRF1 Human oleic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA and FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NRF1 Human oxaliplatin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of NRF1 mRNA CTD PMID:25729387 NRF1 Human oxybenzone increases expression ISO Nrf1 (Rattus norvegicus) 6480464 oxybenzone results in increased expression of NRF1 mRNA CTD PMID:30316929 NRF1 Human ozone increases expression ISO Nrf1 (Mus musculus) 6480464 Ozone results in increased expression of NRF1 mRNA CTD PMID:27240593 NRF1 Human p-toluidine decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 4-toluidine results in decreased expression of NRF1 mRNA CTD PMID:27638505 NRF1 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of NRF1 mRNA CTD PMID:29067470 NRF1 Human paracetamol increases expression ISO Nrf1 (Mus musculus) 6480464 Acetaminophen results in increased expression of NRF1 protein CTD PMID:28827156 and PMID:33271250 NRF1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of NRF1 mRNA CTD PMID:36331819 NRF1 Human perfluorooctanoic acid increases expression ISO Nrf1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of NRF1 mRNA CTD PMID:19616056 NRF1 Human potassium chloride increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Potassium Chloride results in increased expression of NRF1 mRNA and Potassium Chloride results in increased expression of NRF1 protein CTD PMID:20438809 NRF1 Human pregnenolone 16alpha-carbonitrile decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in decreased expression of NRF1 mRNA CTD PMID:30047161 NRF1 Human propham increases expression EXP 6480464 propham results in increased expression of NRF1 mRNA CTD PMID:33352482 NRF1 Human pyrimethanil increases expression EXP 6480464 pyrimethanil results in increased expression of NRF1 mRNA CTD PMID:33352482 NRF1 Human pyrroloquinoline quinone increases expression EXP 6480464 PQQ Cofactor results in increased expression of NRF1 mRNA CTD PMID:28578007 NRF1 Human quercetin multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [aluminum lactate results in decreased expression of NRF1 mRNA] more ... CTD PMID:21775390 and PMID:26493151 NRF1 Human raloxifene multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] and Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] CTD PMID:22105178 NRF1 Human raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of NRF1 mRNA CTD PMID:22105178 NRF1 Human reactive oxygen species multiple interactions EXP 6480464 NRF1 mutant form promotes the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species] CTD PMID:21401886 NRF1 Human resveratrol multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:22105178 more ... NRF1 Human resveratrol multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Dietary Fats co-treated with Resveratrol] results in increased expression of NRF1 mRNA more ... CTD PMID:24041027 more ... NRF1 Human resveratrol increases expression EXP 6480464 resveratrol results in increased expression of NRF1 mRNA CTD PMID:22105178 and PMID:24041027 NRF1 Human resveratrol multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of NRF1 mRNA] more ... CTD PMID:20438809 more ... NRF1 Human resveratrol increases expression ISO Nrf1 (Mus musculus) 6480464 Resveratrol results in increased expression of NRF1 mRNA and Resveratrol results in increased expression of NRF1 protein CTD PMID:20561979 more ... NRF1 Human resveratrol increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Resveratrol results in increased expression of NRF1 mRNA and Resveratrol results in increased expression of NRF1 protein CTD PMID:20429690 more ... NRF1 Human resveratrol decreases expression ISO Nrf1 (Mus musculus) 6480464 resveratrol results in decreased expression of NRF1 mRNA CTD PMID:21270273 NRF1 Human rotenone increases expression ISO Nrf1 (Mus musculus) 6480464 Rotenone results in increased expression of NRF1 mRNA CTD PMID:21536665 NRF1 Human rotenone multiple interactions ISO Nrf1 (Mus musculus) 6480464 PPARGC1A protein affects the reaction [Rotenone results in increased expression of NRF1 mRNA] CTD PMID:21536665 NRF1 Human selenium atom multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA] CTD PMID:17936198 NRF1 Human selenium atom increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Selenium results in increased expression of NRF1 mRNA CTD PMID:17936198 NRF1 Human sodium arsenite multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of and affects the localization of NRF1 protein CTD PMID:27425645 NRF1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of NRF1 mRNA CTD PMID:29301061 and PMID:34032870 NRF1 Human sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of NRF1 mRNA CTD PMID:29319823 NRF1 Human sodium arsenite decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of NRF1 mRNA and sodium arsenite results in decreased expression of NRF1 protein CTD PMID:26767369 and PMID:27425645 NRF1 Human sodium hydrogensulfite multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA] CTD PMID:26980303 NRF1 Human sodium hydrogensulfite decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 sodium bisulfite results in decreased expression of NRF1 mRNA and sodium bisulfite results in decreased expression of NRF1 protein CTD PMID:26980303 NRF1 Human Soman decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Soman results in decreased expression of NRF1 mRNA CTD PMID:19281266 NRF1 Human stavudine increases expression ISO Nrf1 (Mus musculus) 6480464 Stavudine results in increased expression of NRF1 mRNA CTD PMID:17926646 NRF1 Human sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of NRF1 protein CTD PMID:27993529 NRF1 Human sulfur dioxide increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Sulfur Dioxide results in increased expression of NRF1 protein CTD PMID:22677886 NRF1 Human sulfur dioxide decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Sulfur Dioxide results in decreased expression of NRF1 mRNA and Sulfur Dioxide results in decreased expression of NRF1 protein CTD PMID:26980303 NRF1 Human T-2 toxin multiple interactions ISO Nrf1 (Mus musculus) 6480464 6-hydroxy-2 more ... CTD PMID:27363784 NRF1 Human T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of NRF1 mRNA and T-2 Toxin results in decreased expression of NRF1 protein CTD PMID:35842139 NRF1 Human T-2 toxin affects expression ISO Nrf1 (Rattus norvegicus) 6480464 T-2 Toxin affects the expression of NRF1 mRNA CTD PMID:29870751 NRF1 Human T-2 toxin multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA] more ... CTD PMID:31470059 and PMID:35842139 NRF1 Human T-2 toxin decreases expression ISO Nrf1 (Mus musculus) 6480464 T-2 Toxin results in decreased expression of NRF1 protein CTD PMID:27363784 NRF1 Human tetrachloromethane decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of NRF1 protein CTD PMID:26882442 NRF1 Human tetrachloromethane increases expression ISO Nrf1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of NRF1 mRNA CTD PMID:31150632 NRF1 Human tetrachloromethane multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of NRF1 protein] and schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NRF1 mRNA] CTD PMID:26882442 and PMID:31150632 NRF1 Human thapsigargin multiple interactions EXP 6480464 NRF1 protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein] CTD PMID:22378314 NRF1 Human thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of NRF1 mRNA CTD PMID:22378314 NRF1 Human topotecan multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of NRF1 mRNA CTD PMID:25729387 NRF1 Human topotecan decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 Topotecan results in decreased expression of NRF1 mRNA CTD PMID:25729387 NRF1 Human trimellitic anhydride increases expression ISO Nrf1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of NRF1 mRNA CTD PMID:19042947 NRF1 Human Triptolide decreases expression ISO Nrf1 (Mus musculus) 6480464 triptolide results in decreased expression of NRF1 mRNA CTD PMID:29723566 NRF1 Human Triptolide multiple interactions ISO Nrf1 (Rattus norvegicus) 6480464 7 more ... CTD PMID:36436616 NRF1 Human Triptolide decreases expression ISO Nrf1 (Rattus norvegicus) 6480464 triptolide results in decreased expression of NRF1 mRNA CTD PMID:36436616 NRF1 Human triptonide affects expression ISO Nrf1 (Mus musculus) 6480464 triptonide affects the expression of NRF1 mRNA CTD PMID:33045310 NRF1 Human troglitazone increases expression ISO Nrf1 (Rattus norvegicus) 6480464 troglitazone results in increased expression of NRF1 mRNA CTD PMID:14563825 NRF1 Human tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of NRF1 mRNA CTD PMID:22378314 NRF1 Human uranium atom affects expression EXP 6480464 Uranium affects the expression of NRF1 mRNA CTD PMID:15672453 NRF1 Human urethane increases expression EXP 6480464 Urethane results in increased expression of NRF1 mRNA CTD PMID:28818685 NRF1 Human valproic acid decreases expression ISO Nrf1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of NRF1 mRNA CTD PMID:21427059 NRF1 Human valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of NRF1 mRNA CTD PMID:28001369 NRF1 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of NRF1 mRNA CTD PMID:25979313 NRF1 Human zidovudine increases expression ISO Nrf1 (Mus musculus) 6480464 Zidovudine results in increased expression of NRF1 mRNA CTD PMID:17926646 NRF1 Human zinc atom multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of NRF1 mRNA CTD PMID:18593933 NRF1 Human zinc(0) multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of NRF1 mRNA CTD PMID:18593933
