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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:valine, leucine and isoleucine degradation pathway
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Accession:PW:0000071 term browser browse the term
Definition:Those metabolic reactions involved in the degradation of valine, leucine and isoleucine - the three dietary-essential branched amino acids.
Synonyms:related_synonym: Branched-chain amino acid catabolism;   branched-chain amino acid catabolic process


show annotations for term's descendants           Sort by:
valine, leucine and isoleucine degradation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A IEA KEGG rno:00280 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B IEA KEGG rno:00280 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 ISO SMPDB SMP:00032 NCBI chr 8:25,382,271...25,406,404
Ensembl chr 8:25,382,273...25,406,414 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 IEA KEGG rno:00280 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA KEGG rno:00280 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 IEA KEGG rno:00280 NCBI chr 1:218,201,443...218,241,410 JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IEA KEGG rno:00280 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 IEA KEGG rno:00280 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA KEGG rno:00280 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IEA KEGG rno:00280 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Aox1 aldehyde oxidase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Aox2 aldehyde oxidase 2 IEA KEGG rno:00280 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IEA
IDA		 KEGG
RGD		 PMID:11733007 rno:00280, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dld dihydrolipoamide dehydrogenase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase IEA KEGG rno:00280 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEA KEGG rno:00280 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA KEGG rno:00280 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta IEA KEGG rno:00280 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEA KEGG rno:00280 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575 		JBrowse link
G Lao1 L-amino acid oxidase 1 IEA KEGG rno:00280 NCBI chr 5:132,573,698...132,583,591
Ensembl chr 5:132,573,698...132,583,582 		JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972 		JBrowse link
G Mcee methylmalonyl CoA epimerase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484 		JBrowse link
G Mmut methylmalonyl-CoA mutase IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714 		JBrowse link
G Oxct2a 3-oxoacid CoA transferase 2A IEA KEGG rno:00280 NCBI chr 5:135,600,812...135,602,570
Ensembl chr 5:135,591,507...135,602,569 		JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta IEA
ISO		 KEGG
SMPDB		 SMP:00032 rno:00280 NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      amino acid metabolic pathway 308
        amino acid metabolic pathway (KEGG) 266
          valine, leucine and isoleucine degradation pathway 48
paths to the root