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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of axon regeneration
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Accession:GO:0048679 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of axon regeneration.



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regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 acts_upstream_of_or_within ISO MGI:2443718 (PMID:26651291) RGD PMID:26651291 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:1346866|MGI:1346867 (PMID:24733831) RGD PMID:24733831 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Klf4 KLF transcription factor 4 acts_upstream_of_or_within ISO MGI:103038 (PMID:24129709) RGD PMID:24129709 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO MGI:1096335|MGI:1097159 (PMID:26651291) RGD PMID:26651291 NCBI chr 2:191,947,322...192,012,996
Ensembl chr 2:191,949,819...192,012,579
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346867|MGI:88190 (PMID:24733831)
Ensembl
RGD
PMID:24733831 GO_REF:0000107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1346866|MGI:88190 (PMID:24733831)
Ensembl
RGD
PMID:24733831 GO_REF:0000107 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO MGI:2443718 (PMID:26651291) RGD PMID:26651291 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:88190 (PMID:24733831) RGD PMID:24733831 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:21976490)
Ensembl
RGD
PMID:21976490 GO_REF:0000107 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO (PMID:19855390) RGD PMID:19855390 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kiaa0319 KIAA0319 homolog acts_upstream_of_or_within ISO (PMID:28334068)
MGI:4362922 (PMID:28334068)
RGD PMID:28334068 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Tnr tenascin R involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2154583 (PMID:16870730)
Ensembl
RGD
PMID:16870730 GO_REF:0000107 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641
JBrowse link
negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers2 ceramide synthase 2 involved_in IMP PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
JBrowse link
G Epha4 Eph receptor A4 involved_in
NOT
IMP
ISO
ISS
(PMID:15537875)
GO_REF:0000024
RGD
UniProt
PMID:15537875 PMID:17970742 PMID:17418490 GO_REF:0000024, RGD:5688750, RGD:5688782 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Fignl2 fidgetin-like 2 involved_in IMP PMID:33872220 UniProt PMID:33872220 RGD:401901234 NCBI chr 7:132,160,006...132,187,896
Ensembl chr 7:132,162,390...132,164,336
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO (PMID:26203138) RGD PMID:26203138 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:24167472)
Ensembl
RGD
PMID:24167472 GO_REF:0000107 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO (PMID:26651291) RGD PMID:26651291 NCBI chr 2:191,947,322...192,012,996
Ensembl chr 2:191,949,819...192,012,579
JBrowse link
G Neo1 neogenin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:26651291)
Ensembl
RGD
PMID:26651291 GO_REF:0000107 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:26203138) RGD PMID:26203138 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19780196), (PMID:22406547)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19780196 PMID:22406547 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IMP RGD PMID:16585268 RGD:9850138 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
JBrowse link
G Rtn4r reticulon 4 receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:22406547)
UniProt
RGD
PMID:22406547 GO_REF:0000024 NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:22406547)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22406547 GO_REF:0000024 GO_REF:0000107 NCBI chr10:60,043,246...60,116,977
Ensembl chr10:60,043,002...60,116,978
JBrowse link
G Xylt1 xylosyltransferase 1 IMP RGD PMID:18765417 RGD:2313145 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spp1 secreted phosphoprotein 1 IEP RGD PMID:15625076 RGD:1581125 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
negative regulation of optical nerve axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtca RNA 3'-terminal phosphate cyclase involved_in ISO (PMID:31919191) RGD PMID:31919191 NCBI chr 2:204,455,175...204,476,450
Ensembl chr 2:204,455,175...204,476,460
JBrowse link
positive regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp1 LDL receptor related protein 1 IDA RGD PMID:23867460 RGD:13800520 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:97380 (PMID:16142215) RGD PMID:16142215 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
positive regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IMP RGD PMID:24873730 RGD:405878058 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:24733831) RGD PMID:24733831 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cntf ciliary neurotrophic factor involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:15574731 GO_REF:0000033, RGD:1626128 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IDA RGD PMID:9512405 RGD:7205517 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Flna filamin A involved_in ISO (PMID:26157139) RGD PMID:26157139 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
GO_REF:0000024
(PMID:28453791)
UniProt
RGD
PMID:28453791 GO_REF:0000024 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:23349896 RGD:10046026 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Mif macrophage migration inhibitory factor IMP RGD PMID:12456989 RGD:1642004 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 IMP RGD PMID:18431495 RGD:2306515 NCBI chr10:53,505,628...53,582,025
Ensembl chr10:53,516,491...53,570,907
JBrowse link
G Nrg1 neuregulin 1 IDA RGD PMID:20957456 RGD:10449012 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Ptn pleiotrophin involved_in IDA PMID:27671118 UniProt PMID:27671118 RGD:14397577 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Scarf1 scavenger receptor class F, member 1 involved_in ISO (PMID:18160648) RGD PMID:18160648 NCBI chr10:60,359,213...60,371,516
Ensembl chr10:60,359,197...60,371,516
JBrowse link
G Stk24 serine/threonine kinase 24 IMP RGD PMID:19855390 RGD:2317003 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553
JBrowse link
positive regulation of collateral sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp1 LDL receptor related protein 1 IDA RGD PMID:23867460 RGD:13800520 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
positive regulation of sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pum2 pumilio RNA-binding family member 2 IMP RGD PMID:31606248 RGD:242905203 NCBI chr 6:31,462,879...31,542,976
Ensembl chr 6:31,462,872...31,542,976
JBrowse link
regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Omg oligodendrocyte-myelin glycoprotein acts_upstream_of_or_within ISO MGI:3821628 (PMID:18692574) RGD PMID:18692574 NCBI chr10:64,461,350...64,464,084
Ensembl chr10:64,461,350...64,464,084
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    regulation of biological process 13131
      regulation of response to stimulus 4294
        regulation of response to external stimulus 1181
          regulation of axon regeneration 39
            negative regulation of axon regeneration + 17
            positive regulation of axon regeneration + 16
            regulation of collateral sprouting of intact axon in response to injury + 2
            regulation of optical nerve axon regeneration + 1
Path 2
Term Annotations click to browse term
  biological_process 20069
    developmental process 7067
      anatomical structure development 6570
        multicellular organism development 5298
          system development 4583
            nervous system development 2848
              neurogenesis 2111
                generation of neurons 1807
                  neuron differentiation 1722
                    neuron development 1417
                      neuron projection development 1241
                        neuron projection regeneration 89
                          axon regeneration 75
                            regulation of axon regeneration 39
                              negative regulation of axon regeneration + 17
                              positive regulation of axon regeneration + 16
                              regulation of collateral sprouting of intact axon in response to injury + 2
                              regulation of optical nerve axon regeneration + 1
paths to the root