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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of axon regeneration
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Accession:GO:0048681 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
Synonyms:exact_synonym: down regulation of axon regeneration;   downregulation of axon regeneration
 narrow_synonym: inhibition of axon regeneration


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negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers2 ceramide synthase 2 IMP PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Epha4 Eph receptor A4 NOT IMP
ISS
ISO
GO_REF:0000024
(MGI:MGI:3530975|PMID:15537875)
UniProt
RGD
PMID:15537875, PMID:17970742, PMID:17418490 GO_REF:0000024, MGI:MGI:3530975, RGD:5688750, RGD:5688782 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F ISO (MGI:MGI:5694525|PMID:26203138) RGD PMID:26203138 MGI:MGI:5694525 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524
JBrowse link
G Klk8 kallikrein related-peptidase 8 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3766680|PMID:17629414)
Ensembl
UniProt
RGD
PMID:17629414 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3766680 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:6274963|PMID:24167472)
Ensembl
RGD
PMID:24167472 GO_REF:0000107, MGI:MGI:6274963 NCBI chr14:85,441,209...85,503,661
Ensembl chr14:85,438,707...85,484,275
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 ISO (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 2:206,928,708...206,997,915
Ensembl chr 2:206,931,204...206,997,519
JBrowse link
G Neo1 neogenin 1 ISO (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Pten phosphatase and tensin homolog ISO (MGI:MGI:5694525|PMID:26203138) RGD PMID:26203138 MGI:MGI:5694525 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:4880863|PMID:19780196), (MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19780196, PMID:22406547 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4880863, MGI:MGI:5461303 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IMP RGD PMID:16585268 RGD:9850138 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
RGD
UniProt
PMID:22406547 GO_REF:0000024, MGI:MGI:5461303 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 ISO
ISS
(MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
RGD
UniProt
PMID:22406547 GO_REF:0000024, MGI:MGI:5461303 NCBI chr10:62,035,866...62,109,075
Ensembl chr10:62,035,866...62,109,078
JBrowse link
G Xylt1 xylosyltransferase 1 IMP RGD PMID:18765417 RGD:2313145 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGD1307443 similar to mKIAA0319 protein ISO MGI:MGI:4362922 (MGI:MGI:5904726|PMID:28334068)
(PMID:28334068)
RGD PMID:28334068 MGI:MGI:5904726 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Tnr tenascin R ISO
IEA
MGI:MGI:2154583 (MGI:MGI:3652670|PMID:16870730)
GO_REF:0000107
RGD
Ensembl
PMID:16870730 GO_REF:0000107, MGI:MGI:3652670 NCBI chr13:77,602,249...77,678,385
Ensembl chr13:77,485,113...77,678,437
JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spp1 secreted phosphoprotein 1 IEP RGD PMID:15625076 RGD:1581125 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
negative regulation of formation of growth cone in injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtn4 reticulon 4 ISO MGI:MGI:3623522 (MGI:MGI:3621687|PMID:12718855) RGD PMID:12718855 MGI:MGI:3621687 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to external stimulus 3202
        negative regulation of response to external stimulus 381
          negative regulation of axon regeneration 17
            negative regulation of collateral sprouting of intact axon in response to injury 1
            negative regulation of optical nerve axon regeneration 0
            negative regulation of sprouting of injured axon + 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              neurogenesis 1938
                generation of neurons 1781
                  neuron differentiation 1617
                    neuron development 1323
                      neuron projection development 1163
                        neuron projection regeneration 83
                          axon regeneration 72
                            regulation of axon regeneration 38
                              negative regulation of axon regeneration 17
                                negative regulation of collateral sprouting of intact axon in response to injury 1
                                negative regulation of optical nerve axon regeneration 0
                                negative regulation of sprouting of injured axon + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.