Pum2 (pumilio RNA-binding family member 2) - Rat Genome Database
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Gene: Pum2 (pumilio RNA-binding family member 2) Rattus norvegicus
Analyze
Symbol: Pum2
Name: pumilio RNA-binding family member 2
RGD ID: 1311024
Description: Predicted to have mRNA 3'-UTR binding activity and miRNA binding activity. Predicted to be involved in regulation of chromosome segregation; regulation of gene expression; and stress granule assembly. Predicted to localize to several cellular components, including cytoplasmic stress granule; nuclear membrane; and perinuclear region of cytoplasm. Orthologous to human PUM2 (pumilio RNA binding family member 2); INTERACTS WITH 2,4-dinitrotoluene; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC298874; pumilio 2; pumilio 2 (Drosophila); pumilio homolog 2; pumilio homolog 2 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2631,462,879 - 31,542,976 (+)NCBI
Rnor_6.0 Ensembl633,786,197 - 33,865,687 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0633,786,184 - 33,865,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0643,568,680 - 43,648,168 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4632,153,090 - 32,233,940 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1632,155,891 - 32,236,909 (+)NCBI
Celera630,911,640 - 30,990,191 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:11780640   PMID:16775137   PMID:18776931   PMID:19168546   PMID:19197241   PMID:19861488   PMID:20133610   PMID:22345517   PMID:22658674   PMID:22681889   PMID:23739961   PMID:25100735  
PMID:25340845   PMID:26724866   PMID:28431233   PMID:31606248   PMID:32437714  


Genomics

Comparative Map Data
Pum2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2631,462,879 - 31,542,976 (+)NCBI
Rnor_6.0 Ensembl633,786,197 - 33,865,687 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0633,786,184 - 33,865,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0643,568,680 - 43,648,168 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4632,153,090 - 32,233,940 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1632,155,891 - 32,236,909 (+)NCBI
Celera630,911,640 - 30,990,191 (+)NCBICelera
Cytogenetic Map6q14NCBI
PUM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl220,248,691 - 20,352,234 (-)EnsemblGRCh38hg38GRCh38
GRCh38220,248,691 - 20,352,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37220,448,453 - 20,550,585 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37220,448,452 - 20,552,014 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36220,311,934 - 20,390,625 (-)NCBINCBI36hg18NCBI36
Build 34220,370,080 - 20,448,772NCBI
Celera220,311,202 - 20,389,869 (-)NCBI
Cytogenetic Map2p24.1NCBI
HuRef220,205,916 - 20,284,863 (-)NCBIHuRef
CHM1_1220,377,810 - 20,480,003 (-)NCBICHM1_1
Pum2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39128,724,092 - 8,802,583 (+)NCBIGRCm39mm39
GRCm38128,674,092 - 8,752,583 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl128,674,134 - 8,752,581 (+)EnsemblGRCm38mm10GRCm38
MGSCv37128,680,940 - 8,759,389 (+)NCBIGRCm37mm9NCBIm37
MGSCv36128,700,689 - 8,776,347 (+)NCBImm8
Celera129,059,182 - 9,137,555 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
Pum2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554692,810,573 - 2,886,611 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554692,810,825 - 2,886,911 (-)NCBIChiLan1.0ChiLan1.0
PUM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A20,350,669 - 20,455,002 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A20,350,690 - 20,435,174 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A20,235,169 - 20,337,667 (-)NCBIMhudiblu_PPA_v0panPan3
PUM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1715,261,389 - 15,354,586 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11715,258,264 - 15,354,001 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Pum2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649311,067,318 - 11,154,133 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PUM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3117,858,031 - 117,965,566 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13117,857,930 - 117,965,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23125,827,213 - 125,934,624 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PUM2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11487,368,288 - 87,473,282 (+)NCBI
ChlSab1.1 Ensembl1487,391,219 - 87,474,676 (+)Ensembl
Pum2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247382,951,253 - 3,042,905 (-)NCBI

Position Markers
D6Got27  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0633,862,511 - 33,862,791NCBIRnor6.0
Rnor_5.0643,644,986 - 43,645,266UniSTSRnor5.0
RGSC_v3.4632,230,757 - 32,231,038RGDRGSC3.4
RGSC_v3.4632,230,758 - 32,231,038UniSTSRGSC3.4
RGSC_v3.1632,233,710 - 32,233,991RGD
Cytogenetic Map6q14UniSTS
RH141048  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0633,865,299 - 33,865,503NCBIRnor6.0
Rnor_5.0643,647,774 - 43,647,978UniSTSRnor5.0
RGSC_v3.4632,233,546 - 32,233,750UniSTSRGSC3.4
Celera630,989,797 - 30,990,001UniSTS
Cytogenetic Map6q14UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6135623029Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6135623029Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6135623029Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6135623029Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6135623029Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6141917988Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6142388212Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6142388212Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142388212Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6142388212Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6142388212Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6143665660Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6143665660Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6143665660Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6144015370Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6144570292Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6175623393Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112039346120393Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)6112039375023446Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)62537030111715717Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)6616172276002731Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6616172276002731Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)67009971115379601Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)71017386255173862Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)61312295834367603Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)61312295857516539Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61681010761810107Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61681010761810107Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)61941788764417887Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62151530265784818Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62204285484763421Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62204285484763421Rat

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir134rno-miR-134-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19197241

Predicted Target Of
Summary Value
Count of predictions:518
Count of miRNA genes:234
Interacting mature miRNAs:320
Transcripts:ENSRNOT00000008359
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY724506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000008359   ⟹   ENSRNOP00000008359
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl633,786,627 - 33,865,687 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082598   ⟹   ENSRNOP00000074592
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl633,786,197 - 33,863,059 (+)Ensembl
RefSeq Acc Id: NM_001106715   ⟹   NP_001100185
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,463,320 - 31,542,976 (+)NCBI
Rnor_6.0633,786,627 - 33,865,693 (+)NCBI
Rnor_5.0643,568,680 - 43,648,168 (+)NCBI
RGSC_v3.4632,153,090 - 32,233,940 (+)RGD
Celera630,911,640 - 30,990,191 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239879   ⟹   XP_006239941
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
Rnor_6.0633,786,184 - 33,865,688 (+)NCBI
Rnor_5.0643,568,680 - 43,648,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239880   ⟹   XP_006239942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
Rnor_6.0633,786,205 - 33,865,688 (+)NCBI
Rnor_5.0643,568,680 - 43,648,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239883   ⟹   XP_006239945
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
Rnor_6.0633,786,205 - 33,865,688 (+)NCBI
Rnor_5.0643,568,680 - 43,648,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239884   ⟹   XP_006239946
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0633,809,639 - 33,865,688 (+)NCBI
Rnor_5.0643,568,680 - 43,648,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764580   ⟹   XP_008762802
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0633,786,531 - 33,865,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594073   ⟹   XP_017449562
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
Rnor_6.0633,786,205 - 33,865,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039111922   ⟹   XP_038967850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111923   ⟹   XP_038967851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111924   ⟹   XP_038967852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111925   ⟹   XP_038967853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111926   ⟹   XP_038967854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111928   ⟹   XP_038967856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111929   ⟹   XP_038967857
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111930   ⟹   XP_038967858
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111931   ⟹   XP_038967859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111932   ⟹   XP_038967860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,938 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111933   ⟹   XP_038967861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,938 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111934   ⟹   XP_038967862
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111935   ⟹   XP_038967863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111936   ⟹   XP_038967864
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111938   ⟹   XP_038967866
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111939   ⟹   XP_038967867
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,462,879 - 31,542,969 (+)NCBI
RefSeq Acc Id: XM_039111940   ⟹   XP_038967868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2631,496,487 - 31,542,971 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100185   ⟸   NM_001106715
- UniProtKB: D3ZQL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239941   ⟸   XM_006239879
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006239942   ⟸   XM_006239880
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006239945   ⟸   XM_006239883
- Peptide Label: isoform X17
- UniProtKB: A0A0G2K8F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239946   ⟸   XM_006239884
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008762802   ⟸   XM_008764580
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449562   ⟸   XM_017594073
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: ENSRNOP00000074592   ⟸   ENSRNOT00000082598
RefSeq Acc Id: ENSRNOP00000008359   ⟸   ENSRNOT00000008359
RefSeq Acc Id: XP_038967850   ⟸   XM_039111922
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967851   ⟸   XM_039111923
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038967862   ⟸   XM_039111934
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038967863   ⟸   XM_039111935
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038967852   ⟸   XM_039111924
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038967853   ⟸   XM_039111925
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038967864   ⟸   XM_039111936
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038967866   ⟸   XM_039111938
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038967854   ⟸   XM_039111926
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038967856   ⟸   XM_039111928
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038967867   ⟸   XM_039111939
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038967857   ⟸   XM_039111929
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038967858   ⟸   XM_039111930
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038967859   ⟸   XM_039111931
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038967861   ⟸   XM_039111933
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038967860   ⟸   XM_039111932
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038967868   ⟸   XM_039111940
- Peptide Label: isoform X20
Protein Domains
PUM-HD

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694489
Promoter ID:EPDNEW_R5009
Type:initiation region
Name:Pum2_1
Description:pumilio RNA-binding family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0633,786,239 - 33,786,299EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311024 AgrOrtholog
Ensembl Genes ENSRNOG00000006180 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000008359 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074592 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008359 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000082598 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  PUM-HD UniProtKB/TrEMBL
  Pumilio_RNA-bd UniProtKB/TrEMBL
  Pumilio_RNA-bd_rpt UniProtKB/TrEMBL
KEGG Report rno:298874 UniProtKB/TrEMBL
NCBI Gene 298874 ENTREZGENE
Pfam PUF UniProtKB/TrEMBL
PhenoGen Pum2 PhenoGen
PROSITE PUM UniProtKB/TrEMBL
  PUM_HD UniProtKB/TrEMBL
SMART Pumilio UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2K8F9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQL8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Pum2  pumilio RNA-binding family member 2  Pum2  pumilio homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Pum2  pumilio homolog 2 (Drosophila)  Pum2  pumilio 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pum2  pumilio 2 (Drosophila)  Pum2_predicted  pumilio 2 (Drosophila) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pum2_predicted  pumilio 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED