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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of interleukin-1 beta production
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Accession:GO:0032691 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.
Synonyms:exact_synonym: down regulation of interleukin-1 beta production;   downregulation of interleukin-1 beta production;   negative regulation of IL-1 beta production
 narrow_synonym: inhibition of interleukin-1 beta production;   negative regulation of interleukin-1 beta biosynthetic process;   negative regulation of interleukin-1 beta secretion
 alt_id: GO:0050713;   GO:0050724


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negative regulation of interleukin-1 beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:12458630)
GO_REF:0000107		 RGD
Ensembl		 PMID:12458630 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Aqp4 aquaporin 4 IMP RGD PMID:22449442 RGD:8695996 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16378096)		 Ensembl
RGD		 PMID:16378096 GO_REF:0000107 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Cd33 CD33 molecule involved_in ISO (PMID:15597323) RGD PMID:15597323 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1888407 (PMID:12508119)		 Ensembl
RGD		 PMID:12508119 GO_REF:0000107 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS		 (PMID:29164996)
GO_REF:0000024		 RGD
UniProt		 PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IMP PMID:20018408 ARUK-UCL PMID:20018408 RGD:9491804 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Elf4 E74 like ETS transcription factor 4 involved_in ISO (PMID:34326534) RGD PMID:34326534 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:127,590,650...127,630,200 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IMP RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in ISO
IEA		 (PMID:23809162)
GO_REF:0000107		 RGD
Ensembl		 PMID:23809162 GO_REF:0000107 NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO (PMID:23809162) RGD PMID:23809162 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IMP RGD PMID:32428552 RGD:405878062 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in IDA
ISO
ISS		 (PMID:15232612)
GO_REF:0000024		 RGD
UniProt		 PMID:15232612 PMID:19620309 GO_REF:0000024, RGD:12905041 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:15232612)		 UniProt
RGD		 PMID:15232612 GO_REF:0000024 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:32460388)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:32460388 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
ISS		 (PMID:18962899)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:18962899 GO_REF:0000024 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G H19 H19 imprinted maternally expressed transcript IMP RGD PMID:27796346 RGD:156430325 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107		 RGD
Ensembl		 PMID:27277332 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:20041150) RGD PMID:20041150 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Mir101-2 microRNA 101-2 acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:31376096 PMID:32519270 RGD:329337378, RGD:329347827 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23516523) RGD PMID:23516523 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Mir181d microRNA 181d involved_in ISO (PMID:28389653) RGD PMID:28389653 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788 		JBrowse link
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir223 microRNA 223 IMP RGD PMID:31237865 RGD:25824937 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir488 microRNA 488 involved_in ISO (PMID:28915828) RGD PMID:28915828 NCBI chr13:70,683,064...70,683,142
Ensembl chr13:70,683,064...70,683,142 		JBrowse link
G Mir708 microRNA 708 acts_upstream_of ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
G Mir877 microRNA 877 acts_upstream_of ISO (PMID:27542871) RGD PMID:27542871 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560 		JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:31886314) RGD PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:22863753) RGD PMID:22863753 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:12483741) RGD PMID:12483741 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:24407287) RGD PMID:24407287 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Rad21 RAD21 cohesin complex component IMP RGD PMID:36538854 RGD:243065265 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Serpinb1a serpin family B member 1A involved_in ISO
IBA		 (PMID:30692621)
GO_REF:0000033		 RGD
GO_Central		 PMID:30692621 GO_REF:0000033 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102 		JBrowse link
G Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:31,320,135...31,329,151
Ensembl chr17:31,320,556...31,327,935 		JBrowse link
G Spag11a sperm associated antigen 11A involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr16:70,682,326...70,684,067
Ensembl chr16:70,682,326...70,684,069 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 acts_upstream_of_or_within
involved_in		 ISO (PMID:28094437)
(PMID:18006655), (PMID:18342009)		 RGD PMID:18006655 PMID:18342009 PMID:28094437 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:28592261) RGD PMID:28592261 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(PMID:21616078)		 UniProt
RGD		 PMID:21616078 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    negative regulation of biological process 5772
      negative regulation of multicellular organismal process 1342
        negative regulation of cytokine production 385
          negative regulation of interleukin-1 production 52
            negative regulation of interleukin-1 beta production 43
Path 2
Term Annotations click to browse term
  biological_process 20228
    biological regulation 13626
      regulation of biological process 13203
        regulation of cellular process 12840
          regulation of metabolic process 6791
            regulation of biosynthetic process 5551
              regulation of macromolecule biosynthetic process 5349
                regulation of gene expression 5230
                  regulation of cytokine production 908
                    regulation of interleukin-1 production 136
                      regulation of interleukin-1 beta production 114
                        negative regulation of interleukin-1 beta production 43
paths to the root