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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-1 beta production
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Accession:GO:0032691 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.
Synonyms:exact_synonym: down regulation of interleukin-1 beta production;   downregulation of interleukin-1 beta production;   negative regulation of IL-1 beta production
 narrow_synonym: inhibition of interleukin-1 beta production;   negative regulation of interleukin-1 beta biosynthetic process;   negative regulation of interleukin-1 beta secretion
 alt_id: GO:0050713;   GO:0050724



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negative regulation of interleukin-1 beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO MGI:2180086 (MGI:1930064|PMID:11168643) RGD PMID:11168643 MGI:1930064 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:12458630)
GO_REF:0000107
RGD
Ensembl
PMID:12458630 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Aqp4 aquaporin 4 IMP RGD PMID:22449442 RGD:8695996 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO (MGI:3662828|PMID:16378096) RGD PMID:16378096 MGI:3662828 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Cd33 CD33 molecule involved_in ISO (PMID:15597323) RGD PMID:15597323 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1888407 (MGI:3040787|PMID:12508119)
Ensembl
RGD
PMID:12508119 GO_REF:0000107 MGI:3040787 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
(MGI:6120410|PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 MGI:6120410 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IMP PMID:20018408 ARUK-UCL PMID:20018408 RGD:9491804 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Elf4 E74 like ETS transcription factor 4 involved_in ISO (PMID:34326534)
(MGI:6740250|PMID:34326534)
RGD PMID:34326534 MGI:6740250 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:127,590,650...127,630,200
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IMP RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in ISO
IEA
(PMID:23809162)
GO_REF:0000107
RGD
Ensembl
PMID:23809162 GO_REF:0000107 NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272
JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO (PMID:23809162) RGD PMID:23809162 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in IDA
ISO
ISS
(PMID:15232612)
GO_REF:0000024
RGD
UniProt
PMID:15232612 PMID:19620309 GO_REF:0000024, RGD:12905041 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:15232612)
UniProt
RGD
PMID:15232612 GO_REF:0000024 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6478067|PMID:32460388)
UniProt
RGD
PMID:32460388 GO_REF:0000024 MGI:6478067 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
ISS
(PMID:18962899)
(MGI:5009376|PMID:18962899)
GO_REF:0000024
RGD
BHF-UCL
PMID:18962899 GO_REF:0000024 MGI:5009376 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107
RGD
Ensembl
PMID:27277332 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:20041150) RGD PMID:20041150 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Mir101-2 microRNA 101-2 acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
JBrowse link
G Mir101a microRNA 101a acts_upstream_of ISO (PMID:26022377) RGD PMID:26022377 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23516523) RGD PMID:23516523 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961
JBrowse link
G Mir181d microRNA 181d involved_in ISO (PMID:28389653) RGD PMID:28389653 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
JBrowse link
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mir223 microRNA 223 IMP RGD PMID:31237865 RGD:25824937 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir488 microRNA 488 involved_in ISO (PMID:28915828) RGD PMID:28915828 NCBI chr13:70,683,064...70,683,142
Ensembl chr13:70,683,064...70,683,142
JBrowse link
G Mir708 microRNA 708 acts_upstream_of ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963
JBrowse link
G Mir877 microRNA 877 acts_upstream_of ISO (PMID:27542871) RGD PMID:27542871 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:31886314) RGD PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (MGI:5437524|PMID:22863753) RGD PMID:22863753 MGI:5437524 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (PMID:12483741) RGD PMID:12483741 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:5621259|PMID:24407287) RGD PMID:24407287 MGI:5621259 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Serpinb1a serpin family B member 1A involved_in ISO
IBA
(PMID:30692621)
PMID:21873635
(MGI:6294164|PMID:30692621)
RGD PMID:30692621 PMID:21873635 MGI:6294164, RGD:13792537 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:31,320,135...31,329,151
Ensembl chr17:31,320,556...31,327,935
JBrowse link
G Spag11a sperm associated antigen 11A involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr16:70,682,326...70,684,067
Ensembl chr16:70,682,326...70,684,069
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in
acts_upstream_of_or_within
ISO (MGI:3763997|PMID:18006655), (MGI:3777503|PMID:18342009)
(PMID:28094437)
RGD PMID:18006655 PMID:18342009 PMID:28094437 MGI:3763997 MGI:3777503 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294162|PMID:28592261) RGD PMID:28592261 MGI:6294162 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO
ISS
(MGI:5142149|PMID:21616078)
GO_REF:0000024
RGD
UniProt
PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    multicellular organismal process 9238
      cytokine production 865
        negative regulation of cytokine production 373
          negative regulation of interleukin-1 production 49
            negative regulation of interleukin-1 beta production 40
Path 2
Term Annotations click to browse term
  biological_process 19876
    metabolic process 12192
      organic substance metabolic process 11723
        macromolecule metabolic process 10080
          gene expression 6640
            cytokine production 865
              interleukin-1 production 131
                interleukin-1 beta production 109
                  regulation of interleukin-1 beta production 109
                    negative regulation of interleukin-1 beta production 40
paths to the root