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G |
Aadat |
aminoadipate aminotransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936516:2,030,032...2,052,025
Ensembl chrNW_004936516:2,029,715...2,052,041
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
severity |
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:16941710 PMID:30580964 |
RGD:1598532 RGD:24922199 |
NCBI chrNW_004936559:7,177,887...7,312,660
Ensembl chrNW_004936559:7,177,904...7,312,741
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G |
Abcb1 |
ATP binding cassette subfamily B member 1 |
susceptibility |
ISO |
DNA:polymorphism: :c.3751G>A(human) CTD Direct Evidence: marker/mechanism DNA:polymorphism: : c.1465C > T(human) |
RGD CTD |
PMID:17510421 PMID:23488625 PMID:24175826 PMID:25625052 |
RGD:11041138 RGD:14700904 RGD:14700905 |
NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism OMIM:114550 |
CTD MouseDO |
PMID:22022477 |
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NCBI chrNW_004936763:1,339,849...1,415,528
Ensembl chrNW_004936763:1,339,824...1,415,586
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:25842354 |
RGD:11535155 |
NCBI chrNW_004936490:11,039,968...11,086,670
Ensembl chrNW_004936490:11,040,445...11,086,566
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G |
Abce1 |
ATP binding cassette subfamily E member 1 |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:21932399 |
RGD:11041873 |
NCBI chrNW_004936535:3,956,490...3,985,002
Ensembl chrNW_004936535:3,955,682...3,985,223
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
|
ISO |
|
RGD |
PMID:32171747 |
RGD:126907997 |
NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669
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G |
Acaca |
acetyl-CoA carboxylase alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
|
NCBI chrNW_004936490:927,769...1,191,483
Ensembl chrNW_004936490:927,769...1,191,481
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G |
Acer3 |
alkaline ceramidase 3 |
disease_progression |
ISO |
|
RGD |
PMID:30097213 |
RGD:35673325 |
NCBI chrNW_004936498:5,496,991...5,653,206
Ensembl chrNW_004936498:5,496,991...5,653,206
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G |
Acly |
ATP citrate lyase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
|
NCBI chrNW_004936490:16,758,001...16,798,152
Ensembl chrNW_004936490:16,757,985...16,798,237
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G |
Aco2 |
aconitase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936492:407,482...452,538
Ensembl chrNW_004936492:407,482...452,537
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G |
Acox1 |
acyl-CoA oxidase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12771043 PMID:15565109 |
|
NCBI chrNW_004936594:1,115,607...1,140,085
Ensembl chrNW_004936594:1,112,565...1,140,228
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G |
Acsl4 |
acyl-CoA synthetase long chain family member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
|
NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144
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G |
Actb |
actin beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 PMID:21472284 |
|
NCBI chrNW_004936765:667,107...670,627
Ensembl chrNW_004936765:667,053...670,672
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19514085 |
|
NCBI chrNW_004936640:959,405...967,305
Ensembl chrNW_004936640:959,417...968,842
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|
G |
Adamts13 |
ADAM metallopeptidase with thrombospondin type 1 motif 13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936669:3,449,259...3,478,471
Ensembl chrNW_004936669:3,456,494...3,478,512
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G |
Add1 |
adducin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
|
NCBI chrNW_004936477:20,695,109...20,766,053
Ensembl chrNW_004936477:20,691,951...20,766,152
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G |
Adgrg7 |
adhesion G protein-coupled receptor G7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936630:2,569,513...2,624,252
Ensembl chrNW_004936630:2,569,513...2,624,252
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
susceptibility |
ISO |
DNA:SNP:intron:+276T>G (rs1501299) (human) |
RGD |
PMID:23740135 |
RGD:14401720 |
NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928
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G |
Adra1a |
adrenoceptor alpha 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710
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|
G |
Adra2b |
adrenoceptor alpha 2B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936744:249,673...253,040
Ensembl chrNW_004936744:251,467...252,816
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|
G |
Afp |
alpha fetoprotein |
severity treatment disease_progression |
ISO |
protein:increased expression:serum (human) CTD Direct Evidence: marker/mechanism associated with hepatitis B |
RGD CTD |
PMID:9029167 PMID:15276417 PMID:22147961 PMID:22392353 PMID:24012840 PMID:25968302 PMID:25999787 PMID:28284560 PMID:28611981 PMID:32961231 More...
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RGD:125097525 RGD:126790579 RGD:126790583 RGD:14401581 RGD:152177911 |
NCBI chrNW_004936598:2,058,474...2,077,711
Ensembl chrNW_004936598:2,058,117...2,077,728
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G |
Aicda |
activation induced cytidine deaminase |
|
ISO |
|
RGD |
PMID:18997814 |
RGD:127285629 |
NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
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G |
Ak3 |
adenylate kinase 3 |
|
ISO |
protein:decreased expression:liver |
RGD |
PMID:17203974 |
RGD:13842477 |
NCBI chrNW_004936503:497,391...517,011
Ensembl chrNW_004936503:496,965...516,888
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32805337 |
|
NCBI chrNW_004936474:26,680,736...26,696,996
Ensembl chrNW_004936474:26,680,676...26,697,214
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|
G |
Akr1b1 |
aldo-keto reductase family 1 member B |
|
ISO |
protein:increased expression:liver (rat) protein:increased expression:liver (human) |
RGD |
PMID:19422879 PMID:21683810 |
RGD:5509919 RGD:8548685 |
NCBI chrNW_004936579:1,312,175...1,328,397
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|
G |
Akt1 |
AKT serine/threonine kinase 1 |
treatment |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
RGD ClinVar |
PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 PMID:18954143 PMID:19418217 PMID:19487299 PMID:19853286 PMID:20233444 PMID:20453058 PMID:21464312 PMID:21512767 PMID:21793738 PMID:22538770 PMID:22610119 PMID:22722201 PMID:22722839 PMID:22980975 PMID:23237847 PMID:23348505 PMID:23700467 PMID:23728071 PMID:23934607 PMID:24190505 PMID:24657128 PMID:25157968 PMID:25741868 PMID:25999787 PMID:26619011 PMID:28492532 PMID:31801250 More...
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RGD:151893509 RGD:152177911 |
NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
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G |
Akt2 |
AKT serine/threonine kinase 2 |
|
ISO |
protein:increased phosphorylation:liver cancer cell (rat) protein:increased phosphorylation:liver (mouse) |
RGD |
PMID:19309364 PMID:28100771 |
RGD:127285675 RGD:2313299 |
NCBI chrNW_004936661:2,652,568...2,694,039
Ensembl chrNW_004936661:2,652,566...2,694,086
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
susceptibility no_association severity |
ISO |
associated with alcohol use disorder;DNA:missense mutation:cds: (human) DNA:missense mutation:cds: (rs671) (human) DNA:missense mutation:exon 12: (human) protein:decreased expression: liver (human) associated with hepatitis C:DNA:SNP:exon 12 (human) DNA:missense mutation:cds, exon 12:p.E487K (human) associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human) mRNA, protein:decreased expression:liver (human) associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human) |
RGD |
PMID:1916152 PMID:10737710 PMID:12940444 PMID:18439068 PMID:25778454 PMID:26150517 PMID:26827895 PMID:28027570 PMID:29765251 More...
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RGD:11054822 RGD:14696699 RGD:14696778 RGD:14696779 RGD:14700899 RGD:15036809 RGD:15042857 RGD:15042859 RGD:15042862 |
NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414
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|
G |
Aldh7a1 |
aldehyde dehydrogenase 7 family member A1 |
severity |
ISO |
mRNA:altered expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936575:6,467,224...6,506,052
Ensembl chrNW_004936575:6,467,340...6,506,006
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|
G |
Aldoc |
aldolase, fructose-bisphosphate C |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:3830170 |
RGD:2301136 |
NCBI chrNW_004936538:4,798,991...4,802,700
Ensembl chrNW_004936538:4,798,989...4,802,994
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|
G |
Alx4 |
ALX homeobox 4 |
ameliorates |
ISO |
mRNA, protein:decreased expression:liver |
RGD |
PMID:28081728 PMID:31132711 |
RGD:153323329 RGD:153323330 |
NCBI chrNW_004936562:4,316,550...4,326,022
Ensembl chrNW_004936562:4,314,870...4,326,000
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|
G |
Angptl6 |
angiopoietin like 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936659:491,330...499,409
Ensembl chrNW_004936659:487,983...499,448
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|
G |
Ank3 |
ankyrin 3 |
|
ISO |
protein:decreased expression:liver |
RGD |
PMID:26652480 |
RGD:153344559 |
NCBI chrNW_004936614:2,664,594...2,976,174
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G |
Anln |
anillin actin binding protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936478:11,873,676...11,934,425
Ensembl chrNW_004936478:11,880,103...11,933,247
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G |
Antxr1 |
ANTXR cell adhesion molecule 1 |
treatment |
ISO |
|
RGD |
PMID:20650339 |
RGD:9684932 |
NCBI chrNW_004936491:13,288,986...13,516,878
Ensembl chrNW_004936491:13,288,717...13,516,984
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G |
Anxa10 |
annexin A10 |
disease_progression |
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936516:584,631...644,023
Ensembl chrNW_004936516:564,432...643,586
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G |
Anxa2 |
annexin A2 |
|
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:33675609 |
RGD:152999436 |
NCBI chrNW_004936471:21,274,112...21,329,286
Ensembl chrNW_004936471:21,274,027...21,329,503
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G |
Anxa4 |
annexin A4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936491:13,982,926...14,047,690
Ensembl chrNW_004936491:13,982,677...14,047,690
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G |
Anxa6 |
annexin A6 |
disease_progression |
ISO |
associated with tumor vascularization; protein:decreased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936647:3,978,047...4,029,485
Ensembl chrNW_004936647:3,976,903...4,029,485
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G |
Apc |
APC regulator of WNT signaling pathway |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
OMIM ClinVar |
PMID:1316610 PMID:8381579 PMID:8381580 PMID:9536098 PMID:9824584 PMID:11247896 PMID:11466687 PMID:15311282 PMID:15459959 PMID:17293347 PMID:17489848 PMID:17576681 PMID:18199528 PMID:19793053 PMID:20223039 PMID:20685668 PMID:21859464 PMID:21901162 PMID:22135120 PMID:22425061 PMID:22431159 PMID:22447671 PMID:22703879 PMID:23159591 PMID:23460355 PMID:23484150 PMID:24033266 PMID:24448499 PMID:24573554 PMID:24599579 PMID:24728327 PMID:25186627 PMID:25479140 PMID:25590978 PMID:25637381 PMID:25741868 PMID:25925381 PMID:25980754 PMID:26207792 PMID:26447891 PMID:26467025 PMID:26530882 PMID:26580448 PMID:26690363 PMID:26845104 PMID:26900293 PMID:27028212 PMID:27081525 PMID:27150160 PMID:27600092 PMID:28051113 PMID:28127413 PMID:28135048 PMID:28135145 PMID:28195569 PMID:28492532 PMID:29641532 PMID:29684080 PMID:30267214 PMID:30374176 PMID:31428572 PMID:32390703 PMID:34426522 PMID:35189564 PMID:35264596 More...
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NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453
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G |
Apcs |
amyloid P component, serum |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
|
NCBI chrNW_004936740:979,007...987,312
Ensembl chrNW_004936740:986,460...987,361
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:25109342 PMID:33841550 |
RGD:152998960 |
NCBI chrNW_004936877:666,545...669,351
Ensembl chrNW_004936877:666,523...669,338
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G |
Apln |
apelin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936479:1,889,930...1,899,811
Ensembl chrNW_004936479:1,890,229...1,899,730
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G |
Apoa1 |
apolipoprotein A1 |
disease_progression |
ISO |
protein:decreased expression:plasma (human) associated with hepatitis B; CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:21472284 PMID:23935864 PMID:31211449 |
RGD:153350082 RGD:25671438 |
NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854
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G |
Apoa2 |
apolipoprotein A2 |
|
ISO |
associated with hepatitis B; mRNA:increased expression:liver |
RGD |
PMID:31211449 |
RGD:153350082 |
NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910
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G |
Apoa4 |
apolipoprotein A4 |
disease_progression |
ISO |
associated with hepatitis B; |
RGD |
PMID:31211449 |
RGD:153350082 |
NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127
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G |
Apoc1 |
apolipoprotein C1 |
disease_progression |
ISO |
associated with hepatitis B; |
RGD |
PMID:31211449 |
RGD:153350082 |
NCBI chrNW_004936706:1,519,248...1,520,102
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G |
Apoc2 |
apolipoprotein C2 |
|
ISO |
associated with hepatitis B; mRNA:increased expression:liver |
RGD |
PMID:31211449 |
RGD:153350082 |
NCBI chrNW_004936706:1,531,219...1,531,921
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G |
Apoc3 |
apolipoprotein C3 |
susceptibility disease_progression |
ISO |
associated with Chronic Hepatitis B;DNA:SNP: :rs2854116(human) associated with hepatitis B; |
RGD |
PMID:27547913 PMID:31211449 |
RGD:153344620 RGD:153350082 |
NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603
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G |
Apoc4 |
apolipoprotein C4 |
disease_progression |
ISO |
associated with hepatitis B; |
RGD |
PMID:31211449 |
RGD:153350082 |
NCBI chrNW_004936706:1,528,187...1,530,028
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G |
Apoe |
apolipoprotein E |
|
ISO |
protein:increased expression:liver, serum (mouse) |
RGD |
PMID:21644509 |
RGD:6903288 |
NCBI chrNW_004936706:1,512,438...1,516,805
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G |
Aprt |
adenine phosphoribosyltransferase |
|
ISO |
protein:increased activity:hepatoma (rat) |
RGD |
PMID:6327016 |
RGD:5135035 |
NCBI chrNW_004936641:913,674...916,312
Ensembl chrNW_004936641:913,475...918,748
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G |
Ar |
androgen receptor |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:18639551 |
|
NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932
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G |
Arhgap11a |
Rho GTPase activating protein 11A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936673:1,290,476...1,308,753
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G |
Arhgap44 |
Rho GTPase activating protein 44 |
exacerbates |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:31136984 |
RGD:401901276 |
NCBI chrNW_004936595:5,373,645...5,542,915
Ensembl chrNW_004936595:5,373,476...5,543,073
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G |
Arhgef39 |
Rho guanine nucleotide exchange factor 39 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936524:3,660,364...3,663,664
Ensembl chrNW_004936524:3,660,454...3,663,696
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G |
Arid1a |
AT-rich interaction domain 1A |
treatment exacerbates |
ISO |
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:liver (human) mRNA, protein:decreased expression:liver (human) human gene in mouse model associated with non-alcoholic steatohepatitis |
RGD CTD |
PMID:22561517 PMID:22634756 PMID:22922871 PMID:25975202 PMID:26569409 PMID:26589513 PMID:29113912 PMID:29136504 More...
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RGD:11344640 RGD:125097485 RGD:125097495 RGD:125097519 RGD:126790634 |
NCBI chrNW_004936474:11,148,857...11,197,312
|
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G |
Arid1b |
AT-rich interaction domain 1B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22634756 |
|
NCBI chrNW_004936489:8,811,094...9,202,423
Ensembl chrNW_004936489:9,087,697...9,205,203
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G |
Arid2 |
AT-rich interaction domain 2 |
exacerbates disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism associated with hepatitis B;protein:decreased expression:liver |
RGD CTD |
PMID:21822264 PMID:22634756 PMID:25701229 PMID:27351279 PMID:28498550 PMID:32071245 More...
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RGD:150340708 RGD:150340711 RGD:150340712 RGD:150429631 |
NCBI chrNW_004936512:4,020,303...4,199,390
Ensembl chrNW_004936512:4,020,966...4,196,459
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G |
Arid3a |
AT-rich interaction domain 3A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35179300 |
|
NCBI chrNW_004936588:389,213...418,360
Ensembl chrNW_004936588:394,469...415,893
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G |
Arrb2 |
arrestin beta 2 |
treatment |
ISO |
|
RGD |
PMID:33841550 |
RGD:152998960 |
NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520
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G |
Asf1b |
anti-silencing function 1B histone chaperone |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936659:2,772,310...2,782,687
Ensembl chrNW_004936659:2,770,900...2,782,748
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G |
Asl |
argininosuccinate lyase |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936543:7,688,788...7,699,842
Ensembl chrNW_004936543:7,688,741...7,699,851
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
|
ISO |
protein:increased activity:serum (rat) |
RGD |
PMID:10081 |
RGD:2316006 |
NCBI chrNW_004936585:2,834,202...2,854,740
Ensembl chrNW_004936585:2,834,008...2,855,387
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Aspg |
asparaginase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936621:1,140,651...1,163,608
Ensembl chrNW_004936621:1,140,658...1,163,589
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G |
Aspm |
assembly factor for spindle microtubules |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:18676753 PMID:28284560 |
RGD:13439743 |
NCBI chrNW_004936567:6,653,382...6,701,856
Ensembl chrNW_004936567:6,653,728...6,701,752
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G |
Ass1 |
argininosuccinate synthase 1 |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) |
RGD |
PMID:12359751 PMID:30901224 |
RGD:152995286 RGD:4140479 |
NCBI chrNW_004936487:17,482,307...17,527,407
Ensembl chrNW_004936487:17,486,826...17,527,435
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Atg101 |
autophagy related 101 |
disease_progression |
ISO |
|
RGD |
PMID:35592424 |
RGD:153350091 |
NCBI chrNW_004936512:9,518,128...9,525,986
Ensembl chrNW_004936512:9,518,074...9,526,961
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G |
Atg7 |
autophagy related 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29191453 |
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NCBI chrNW_004936602:1,938,720...2,179,239
Ensembl chrNW_004936602:1,935,507...2,179,256
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G |
Atm |
ATM serine/threonine kinase |
exacerbates |
ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human) |
CTD RGD |
PMID:12866955 PMID:19919837 |
RGD:126781750 |
NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
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Atp5pb |
ATP synthase peripheral stalk-membrane subunit b |
|
ISO |
associated with hepatitis C |
RGD |
PMID:18932288 |
RGD:14696822 |
NCBI chrNW_004936690:120,572...135,509
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936594:354,416...359,415
Ensembl chrNW_004936594:353,980...359,414
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Atp7b |
ATPase copper transporting beta |
onset |
ISO |
|
RGD |
PMID:8291609 |
RGD:15036817 |
NCBI chrNW_004936565:4,694,294...4,763,661
Ensembl chrNW_004936565:4,694,281...4,763,773
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G |
Aurka |
aurora kinase A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936875:295,238...310,457
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G |
Aurkb |
aurora kinase B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936595:1,435,601...1,437,423
Ensembl chrNW_004936595:1,435,852...1,440,351
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G |
Axin1 |
axin 1 |
disease_progression |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma protein:decreased expression:liver (human) associated with Hepatitis B, Chronic,DNA:SNP, haplotype:exon:(rs1805105) T>C (human) |
OMIM ClinVar RGD |
PMID:10700176 PMID:25741868 PMID:26968103 PMID:28492532 PMID:31514071 PMID:37582359 More...
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RGD:14402039 RGD:150530482 |
NCBI chrNW_004936501:599,963...633,837
Ensembl chrNW_004936501:599,919...633,873
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G |
Axin2 |
axin 2 |
|
ISO |
protein:increased expression:liver: |
RGD |
PMID:11809809 |
RGD:151356508 |
NCBI chrNW_004936541:7,155,963...7,242,466
Ensembl chrNW_004936541:7,211,985...7,242,470
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G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
disease_progression |
ISO |
associated with hepatitis B;mRNA:decreased expression:liver |
RGD |
PMID:22625427 PMID:26902423 PMID:27993894 |
RGD:153350130 RGD:153350132 RGD:153350133 |
NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190
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G |
Azin1 |
antizyme inhibitor 1 |
disease_progression |
ISO |
RNA:increased editing:liver |
RGD |
PMID:23291631 |
RGD:14700705 |
NCBI chrNW_004936470:40,801,943...40,832,543
Ensembl chrNW_004936470:40,801,943...40,834,003
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G |
Banf1 |
BAF nuclear assembly factor 1 |
treatment |
ISO |
mRNA, protein:increased expression:liver (human) mRNA, protein:increased expression:liver (rat) |
RGD |
PMID:29059470 |
RGD:155791679 |
NCBI chrNW_004936599:3,553,190...3,555,167
Ensembl chrNW_004936599:3,553,193...3,555,162
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Bax |
BCL2 associated X, apoptosis regulator |
treatment |
ISO |
|
RGD |
PMID:33841550 |
RGD:152998960 |
NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820
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G |
Bcl2 |
BCL2 apoptosis regulator |
treatment |
ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:28100771 PMID:33841550 |
RGD:127285675 RGD:152998960 |
NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
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G |
Bcl2l1 |
BCL2 like 1 |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic mRNA:increased expression:liver (mouse) |
CTD RGD |
PMID:10629087 PMID:11509945 PMID:28100771 PMID:33841550 |
RGD:127285675 RGD:152998960 |
NCBI chrNW_004936485:18,654,046...18,707,324
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G |
Bco2 |
beta-carotene oxygenase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936612:2,262,115...2,294,287
Ensembl chrNW_004936612:2,262,066...2,294,255
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G |
Bcorl1 |
BCL6 corepressor like 1 |
disease_progression |
ISO |
|
RGD |
PMID:26879601 PMID:29679906 |
RGD:11556159 RGD:150340705 |
NCBI chrNW_004936479:1,539,676...1,605,647
Ensembl chrNW_004936479:1,538,051...1,606,344
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G |
Bid |
BH3 interacting domain death agonist |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15289866 |
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NCBI chrNW_004936807:708,340...750,127
Ensembl chrNW_004936807:708,276...750,093
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G |
Birc3 |
baculoviral IAP repeat containing 3 |
ameliorates treatment exacerbates |
ISO |
human cell line in a mouse model associated with hepatitis B;mRNA, protein:increased expression:liver (human) |
RGD |
PMID:22682366 PMID:22820591 PMID:30210622 PMID:30368883 PMID:33310033 |
RGD:152998937 RGD:152998984 RGD:152998986 RGD:152998988 RGD:152999010 |
NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555
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G |
Birc5 |
baculoviral IAP repeat containing 5 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic mRNA:increased expression:liver (human) |
CTD RGD |
PMID:16086872 PMID:20514400 PMID:31964418 |
RGD:153344516 |
NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636
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G |
Birc7 |
baculoviral IAP repeat containing 7 |
exacerbates |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:31964418 |
RGD:153344516 |
NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931
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G |
Blzf1 |
basic leucine zipper nuclear factor 1 |
disease_progression |
ISO |
|
RGD |
PMID:26342799 |
RGD:14398326 |
NCBI chrNW_004936481:17,261,399...17,280,642
Ensembl chrNW_004936481:17,260,472...17,281,309
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
treatment |
ISO |
|
RGD |
PMID:26919246 |
RGD:14928318 |
NCBI chrNW_004936520:5,707,542...5,716,966
Ensembl chrNW_004936520:5,707,778...5,717,024
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G |
Bmper |
BMP binding endothelial regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936478:9,705,634...9,941,382
Ensembl chrNW_004936478:9,705,604...9,941,340
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27222248 |
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NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
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G |
Bsg |
basigin (Ok blood group) |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:36574092 |
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NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287
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G |
Btg2 |
BTG anti-proliferation factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18393292 |
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NCBI chrNW_004936567:1,310,525...1,314,469
Ensembl chrNW_004936567:1,309,658...1,314,515
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936471:3,631,760...3,696,024
Ensembl chrNW_004936471:3,633,536...3,695,684
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G |
C3 |
complement C3 |
|
ISO |
|
RGD |
PMID:23245919 |
RGD:11040806 |
NCBI chrNW_004936588:3,985,732...4,023,221
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G |
C9 |
complement C9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 PMID:28284560 |
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NCBI chrNW_004936518:2,947,956...2,994,892
Ensembl chrNW_004936518:2,958,995...2,994,880
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G |
Ca12 |
carbonic anhydrase 12 |
disease_progression ameliorates |
ISO |
mRNA:altered expression:liver |
RGD |
PMID:29900055 PMID:31934040 PMID:35362480 |
RGD:153352325 RGD:153352328 RGD:155226869 |
NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987
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G |
Ca2 |
carbonic anhydrase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936544:362,591...379,151
Ensembl chrNW_004936544:362,591...380,223
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G |
Ca9 |
carbonic anhydrase 9 |
|
ISO |
mRNA:altered expression:liver |
RGD |
PMID:29900055 |
RGD:155226869 |
NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433
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G |
Cab39 |
calcium binding protein 39 |
disease_progression |
ISO |
|
RGD |
PMID:28605041 |
RGD:14398832 |
NCBI chrNW_004936525:5,955,252...6,002,917
Ensembl chrNW_004936525:5,954,978...6,032,644
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G |
Cad |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
|
ISO |
DNA:amplification:cds (rat) mRNA:increased expression:liver |
RGD |
PMID:2888462 PMID:2914957 PMID:7053379 |
RGD:10755426 RGD:2303530 RGD:5132587 |
NCBI chrNW_004936493:5,308,268...5,332,934
Ensembl chrNW_004936493:5,310,228...5,332,918
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G |
Cadm1 |
cell adhesion molecule 1 |
|
ISO |
DNA, mRNA, protein:hypermethylation, decreased expression:promoter:liver |
RGD |
PMID:17428255 |
RGD:2289095 |
NCBI chrNW_004936542:569,739...883,738
Ensembl chrNW_004936542:565,843...883,609
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G |
Cadm2 |
cell adhesion molecule 2 |
disease_progression |
ISO |
mRNA, protein:decreased expression:liver |
RGD |
PMID:24240726 |
RGD:15092075 |
NCBI chrNW_004936610:3,304,556...4,297,745
Ensembl chrNW_004936610:3,305,551...3,598,837
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G |
Calr |
calreticulin |
treatment exacerbates |
ISO |
human cells and recombinant gene in a mouse model protein:increased expression:liver (human) |
RGD |
PMID:12096119 PMID:24997628 PMID:27055635 |
RGD:150521681 RGD:150521690 RGD:150521691 |
NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430
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G |
Camk2n1 |
calcium/calmodulin dependent protein kinase II inhibitor 1 |
|
ISO |
|
RGD |
PMID:23651211 |
RGD:18337283 |
NCBI chrNW_004936474:6,463,691...6,466,641
Ensembl chrNW_004936474:6,461,050...6,466,641
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936552:3,395,785...3,501,949
Ensembl chrNW_004936552:3,395,649...3,501,940
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G |
Capn3 |
calpain 3 |
|
ISO |
mRNA:decreased expression:skeletal muscle |
RGD |
PMID:10806331 |
RGD:1600777 |
NCBI chrNW_004936471:5,667,839...5,711,822
Ensembl chrNW_004936471:5,668,169...5,711,075
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G |
Carm1 |
coactivator associated arginine methyltransferase 1 |
|
ISO |
mRNA,protein:increased expression:liver: |
RGD |
PMID:23912631 |
RGD:9586718 |
NCBI chrNW_004936659:1,071,883...1,120,917
Ensembl chrNW_004936659:1,090,164...1,123,920
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G |
Casp3 |
caspase 3 |
treatment |
ISO |
|
RGD |
PMID:29133031 PMID:33841550 |
RGD:13782296 RGD:152998960 |
NCBI chrNW_004936554:4,571,072...4,593,765
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G |
Casp8 |
caspase 8 |
severity treatment |
ISO |
associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human) |
OMIM RGD |
PMID:28643196 PMID:29133031 |
RGD:13782296 RGD:14695027 |
NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
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G |
Casp9 |
caspase 9 |
treatment |
ISO |
|
RGD |
PMID:29133031 |
RGD:13782296 |
NCBI chrNW_004936474:3,178,097...3,196,130
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G |
Cat |
catalase |
disease_progression |
ISO |
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:21907168 PMID:33010264 |
RGD:27095879 |
NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422
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G |
Cbfb |
core-binding factor subunit beta |
|
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:17094378 |
RGD:126775147 |
NCBI chrNW_004936475:17,537,273...17,589,383
Ensembl chrNW_004936475:17,537,236...17,589,330
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G |
Cbl |
Cbl proto-oncogene |
disease_progression |
ISO |
|
RGD |
PMID:26474280 |
RGD:11536137 |
NCBI chrNW_004936542:4,136,389...4,235,746
Ensembl chrNW_004936542:4,136,511...4,228,288
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G |
Cbr1 |
carbonyl reductase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21056497 |
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NCBI chrNW_004936500:6,569,708...6,591,266
Ensembl chrNW_004936500:6,458,721...6,591,928
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G |
Cbx2 |
chromobox 2 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936594:3,886,926...3,902,459
Ensembl chrNW_004936594:3,893,772...3,900,000
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G |
Cbx4 |
chromobox 4 |
disease_progression |
ISO |
protein:increased expression:cytoplasm: |
RGD |
PMID:23943028 PMID:24838576 |
RGD:9586738 RGD:9586739 |
NCBI chrNW_004936594:3,943,933...3,950,124
Ensembl chrNW_004936594:3,943,924...3,950,196
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G |
Cbx7 |
chromobox 7 |
|
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:22041561 |
RGD:9587355 |
NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682
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G |
Ccbe1 |
collagen and calcium binding EGF domains 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936497:5,290,068...5,321,656
Ensembl chrNW_004936497:5,290,077...5,321,876
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
|
ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:26569409 |
RGD:11344640 |
NCBI chrNW_004936538:781,687...784,199
Ensembl chrNW_004936538:781,687...784,199
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G |
Ccl14 |
C-C motif chemokine ligand 14 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936490:290,452...293,330
Ensembl chrNW_004936490:290,437...293,360
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
treatment susceptibility |
ISO |
associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human) DNA:polymorphisms:promoter:-403G>A,-28C>G (human) |
RGD |
PMID:21610221 PMID:22374185 PMID:28011329 |
RGD:14995306 RGD:14995333 RGD:14995338 |
NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965
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G |
Ccn1 |
cellular communication network factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17699798 |
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NCBI chrNW_004936608:152,174...155,123
Ensembl chrNW_004936608:151,838...155,358
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G |
Ccna1 |
cyclin A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12029619 |
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NCBI chrNW_004936472:30,574,957...30,586,596
Ensembl chrNW_004936472:30,573,812...30,586,559
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G |
Ccnb1 |
cyclin B1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704
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G |
Ccnb2 |
cyclin B2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936471:20,216,435...20,238,543
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G |
Ccnd1 |
cyclin D1 |
susceptibility |
ISO |
associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human) CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (mouse) |
RGD CTD |
PMID:12029619 PMID:19919837 PMID:22649188 PMID:25822088 PMID:25851350 PMID:26189965 PMID:28100771 More...
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RGD:127285675 RGD:14401586 |
Ensembl chrNW_004936599:973,838...983,316
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Ccnd2 |
cyclin D2 |
severity susceptibility disease_progression |
ISO |
associated with hepatitis B associated with Chronic Hepatitis C;DNA:SNP: :rs1049606(human) DNA:hypermethylation:CpG site |
RGD |
PMID:22004425 PMID:31059558 PMID:33320844 |
RGD:151664743 RGD:151665109 RGD:151665169 |
NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810
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Ccne1 |
cyclin E1 |
ameliorates |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12029619 PMID:17196522 PMID:22634754 PMID:28100771 PMID:29551768 |
RGD:127285675 RGD:153297807 RGD:2289277 |
NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008
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Ccnf |
cyclin F |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936694:1,596,897...1,620,588
Ensembl chrNW_004936694:1,596,766...1,620,643
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Ccng1 |
cyclin G1 |
severity disease_progression treatment |
ISO |
protein:decreased expression:liver (human) protein:increased expression:liver (human) human cells in mouse model |
RGD |
PMID:19584283 PMID:22835824 PMID:23804702 PMID:24034575 PMID:25431954 PMID:26345095 PMID:27982046 PMID:33543294 More...
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RGD:151356922 RGD:151356932 RGD:151356933 RGD:151356967 RGD:151356970 RGD:151356981 RGD:151361198 RGD:151361200 |
NCBI chrNW_004936515:614,287...621,213
Ensembl chrNW_004936515:614,290...619,963
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Ccng2 |
cyclin G2 |
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ISO |
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RGD |
PMID:27982046 |
RGD:151361200 |
NCBI chrNW_004936676:1,026,113...1,035,313
Ensembl chrNW_004936676:1,025,856...1,037,698
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Cd274 |
CD274 molecule |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism associated with hepatitis B associated with hepatitis B |
CTD RGD |
PMID:21912640 PMID:22396772 PMID:30267213 |
RGD:40818240 RGD:41410800 |
NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602
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Cd276 |
CD276 molecule |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:16217749 |
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NCBI chrNW_004936471:32,864,778...32,892,044
Ensembl chrNW_004936471:32,864,781...32,892,095
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Cd34 |
CD34 molecule |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936557:5,030,788...5,051,864
Ensembl chrNW_004936557:5,030,441...5,051,868
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Cd40lg |
CD40 ligand |
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ISO |
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RGD |
PMID:19016771 |
RGD:2313413 |
NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403
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Cd68 |
CD68 molecule |
severity |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:28656201 |
RGD:40924686 |
NCBI chrNW_004936595:858,289...861,131
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Cdc20 |
cell division cycle 20 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936474:24,760,258...24,765,069
Ensembl chrNW_004936474:24,760,298...24,767,725
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Cdc25c |
cell division cycle 25C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936531:7,471,722...7,499,781
Ensembl chrNW_004936531:7,471,722...7,499,766
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Cdc27 |
cell division cycle 27 |
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ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
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NCBI chrNW_004936541:2,700,997...2,762,180
Ensembl chrNW_004936541:2,700,997...2,762,147
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Cdc45 |
cell division cycle 45 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936619:3,420,110...3,452,419
Ensembl chrNW_004936619:3,420,191...3,452,436
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Cdc6 |
cell division cycle 6 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936490:15,360,477...15,370,519
Ensembl chrNW_004936490:15,360,504...15,370,008
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Cdca2 |
cell division cycle associated 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936757:1,195,604...1,249,367
Ensembl chrNW_004936757:1,195,567...1,248,237
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Cdca3 |
cell division cycle associated 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936709:966,559...969,667
Ensembl chrNW_004936709:967,294...968,896
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Cdca5 |
cell division cycle associated 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936599:4,285,007...4,291,875
Ensembl chrNW_004936599:4,284,958...4,291,874
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Cdca8 |
cell division cycle associated 8 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (human) |
CTD RGD |
PMID:28284560 PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936474:19,895,681...19,912,451
Ensembl chrNW_004936474:19,895,640...19,912,933
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Cdh1 |
cadherin 1 |
severity |
ISO |
protein:decreased expression:liver DNA:hypermethylation mRNA:increased expression:liver |
RGD |
PMID:17295234 PMID:18837082 PMID:24840851 PMID:30697077 |
RGD:14402045 RGD:14402046 RGD:14402047 RGD:2289638 |
NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203
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Cdh13 |
cadherin 13 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18425332 PMID:18553387 PMID:28284560 |
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NCBI chrNW_004936641:3,925,185...4,223,421
Ensembl chrNW_004936641:3,931,033...4,224,101
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Cdk1 |
cyclin dependent kinase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human) |
CTD RGD |
PMID:19136513 PMID:28284560 |
RGD:2316317 |
NCBI chrNW_004936614:2,300,682...2,313,611
Ensembl chrNW_004936614:2,300,513...2,313,624
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Cdk12 |
cyclin dependent kinase 12 |
exacerbates |
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:31519701 |
RGD:151361172 |
NCBI chrNW_004936490:14,674,783...14,759,433
Ensembl chrNW_004936490:14,674,800...14,738,818
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Cdk13 |
cyclin dependent kinase 13 |
onset |
ISO |
DNA:amplification: : |
RGD |
PMID:22912832 |
RGD:155641228 |
NCBI chrNW_004936478:15,296,055...15,387,749
Ensembl chrNW_004936478:15,296,055...15,388,309
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Cdk14 |
cyclin dependent kinase 14 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22922871 |
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NCBI chrNW_004936621:3,030,964...3,504,294
Ensembl chrNW_004936621:2,946,035...3,504,306
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G |
Cdk4 |
cyclin dependent kinase 4 |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:26189965 PMID:33841550 |
RGD:152998960 |
NCBI chrNW_004936646:1,886,262...1,889,260
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Cdkn1a |
cyclin dependent kinase inhibitor 1A |
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ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
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Cdkn1b |
cyclin dependent kinase inhibitor 1B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20698225 |
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NCBI chrNW_004936587:4,573,166...4,578,480
Ensembl chrNW_004936587:4,572,728...4,578,461
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Cdkn1c |
cyclin dependent kinase inhibitor 1C |
severity |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:26606000 |
RGD:11354707 |
NCBI chrNW_004936794:1,023,891...1,025,470
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Cdkn2b |
cyclin dependent kinase inhibitor 2B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33010264 |
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NCBI chrNW_004936652:3,576,975...3,582,790
Ensembl chrNW_004936652:3,538,986...3,581,159
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G |
Cdkn2c |
cyclin dependent kinase inhibitor 2C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936522:9,769,761...9,775,374
Ensembl chrNW_004936522:9,769,756...9,775,077
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Cdkn3 |
cyclin dependent kinase inhibitor 3 |
treatment severity |
ISO |
protein:decreased expression:liver associated with alcoholism; protein:increased expression:liver CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver |
RGD CTD |
PMID:22390936 PMID:23292002 PMID:27314282 PMID:28284560 |
RGD:15090800 RGD:15090801 RGD:15090802 |
NCBI chrNW_004936697:669,154...684,077
Ensembl chrNW_004936697:670,785...683,996
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Cdt1 |
chromatin licensing and DNA replication factor 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936641:916,695...925,411
Ensembl chrNW_004936641:917,435...920,981
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Cebpa |
CCAAT enhancer binding protein alpha |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16288022 PMID:21785164 |
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NCBI chrNW_004936570:2,513,561...2,516,213
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Cebpd |
CCAAT enhancer binding protein delta |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 |
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NCBI chrNW_004936590:4,919,862...4,920,612
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Celsr3 |
cadherin EGF LAG seven-pass G-type receptor 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936529:437,476...464,012
Ensembl chrNW_004936529:437,418...464,017
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G |
Cenpa |
centromere protein A |
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ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human) |
CTD RGD |
PMID:21956590 PMID:28284560 |
RGD:36947377 |
NCBI chrNW_004936493:5,715,274...5,720,816
Ensembl chrNW_004936493:5,714,782...5,720,837
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Cenpe |
centromere protein E |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936520:188,601...265,904
Ensembl chrNW_004936520:188,628...265,733
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Cenpf |
centromere protein F |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936628:3,642,281...3,695,262
Ensembl chrNW_004936628:3,643,000...3,695,221
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Cenpm |
centromere protein M |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936492:75,196...88,446
Ensembl chrNW_004936492:75,238...87,912
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Cenpu |
centromere protein U |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936554:4,497,675...4,536,274
Ensembl chrNW_004936554:4,500,486...4,536,239
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Cenpw |
centromere protein W |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936639:3,173,832...3,184,439
Ensembl chrNW_004936639:3,173,385...3,184,454
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Cep131 |
centrosomal protein 131 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936594:4,914,174...4,938,364
Ensembl chrNW_004936594:4,914,358...4,938,394
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Cep164 |
centrosomal protein 164 |
susceptibility |
ISO |
associated with Chronic Hepatitis C;DNA:SNP: :rs573455 (human) |
RGD |
PMID:22004425 |
RGD:151665169 |
NCBI chrNW_004936542:2,544,677...2,609,753
Ensembl chrNW_004936542:2,544,665...2,609,792
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Cep55 |
centrosomal protein 55 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936601:1,455,641...1,474,045
Ensembl chrNW_004936601:1,455,641...1,474,045
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Cetp |
cholesteryl ester transfer protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073
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Cfp |
complement factor properdin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936502:13,391,613...13,398,723
Ensembl chrNW_004936502:13,391,535...13,397,440
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Chaf1b |
chromatin assembly factor 1 subunit B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936500:6,262,207...6,288,833
Ensembl chrNW_004936500:6,262,229...6,288,839
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Chd4 |
chromodomain helicase DNA binding protein 4 |
exacerbates |
ISO |
mRNA:increased expression:liver (human) protein:increased expression:liver (human) |
RGD |
PMID:26095183 PMID:28486105 PMID:32070428 |
RGD:11571740 RGD:153323299 RGD:153323308 |
NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149
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Chd5 |
chromodomain helicase DNA binding protein 5 |
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ISO |
mRNA:decreased expression:liver |
RGD |
PMID:26517514 |
RGD:11537550 |
NCBI chrNW_004936623:988,423...1,046,969
Ensembl chrNW_004936623:991,193...1,046,969
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Ckap2l |
cytoskeleton associated protein 2 like |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936783:1,175,044...1,194,407
Ensembl chrNW_004936783:1,173,627...1,193,813
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Ckap4 |
cytoskeleton associated protein 4 |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:increased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936492:8,635,275...8,638,696
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Cldn1 |
claudin 1 |
severity |
ISO |
associated with liver cirrhosis;protein:increased expression:liver (human) protein:decreased expression:liver (human) |
RGD |
PMID:17270214 PMID:24696415 PMID:24815833 |
RGD:26884345 RGD:26884348 RGD:26884352 |
NCBI chrNW_004936578:98,489...113,125
Ensembl chrNW_004936578:98,273...113,153
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Clec1b |
C-type lectin domain family 1 member B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936902:504,095...510,261
Ensembl chrNW_004936902:504,095...510,261
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G |
Clec4g |
C-type lectin domain family 4 member G |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936588:4,737,278...4,740,750
Ensembl chrNW_004936588:4,738,182...4,740,750
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Clptm1l |
CLPTM1 like |
susceptibility disease_progression |
ISO |
DNA:SNPs::rs401681(human) DNA:SNP: :rs401681(human) |
RGD |
PMID:25339005 PMID:29042796 |
RGD:150530496 RGD:150537100 |
NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750
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Cltrn |
collectrin, amino acid transport regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936470:5,040,831...5,124,611
Ensembl chrNW_004936470:5,040,795...5,124,192
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G |
Cndp1 |
carnosine dipeptidase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936616:3,955,847...3,984,021
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Cnot9 |
CCR4-NOT transcription complex subunit 9 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:26619011 |
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NCBI chrNW_004936569:1,023,057...1,048,968
Ensembl chrNW_004936569:1,022,979...1,049,136
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G |
Cntnap4 |
contactin associated protein family member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936475:24,809,813...25,049,362
Ensembl chrNW_004936475:24,809,531...25,049,854
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G |
Col15a1 |
collagen type XV alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936524:7,481,541...7,591,452
Ensembl chrNW_004936524:7,481,761...7,590,544
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Col18a1 |
collagen type XVIII alpha 1 chain |
severity |
ISO |
Protein:increased expression |
RGD |
PMID:15739185 |
RGD:1600906 |
NCBI chrNW_004936778:847,473...943,038
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G |
Colec10 |
collectin subfamily member 10 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936470:27,416,471...27,449,206
Ensembl chrNW_004936470:27,416,494...27,449,206
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G |
Comt |
catechol-O-methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15341023 |
|
NCBI chrNW_004936619:3,847,059...3,883,866
Ensembl chrNW_004936619:3,876,299...3,882,747
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G |
Cops5 |
COP9 signalosome subunit 5 |
severity |
ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human) |
CTD RGD |
PMID:20698225 PMID:26606000 |
RGD:11354707 |
NCBI chrNW_004936496:7,035,973...7,050,538
Ensembl chrNW_004936496:7,035,924...7,050,786
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G |
Cp |
ceruloplasmin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19229483 |
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NCBI chrNW_004936519:6,431,156...6,473,183
Ensembl chrNW_004936519:6,431,144...6,481,858
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G |
Cpeb3 |
cytoplasmic polyadenylation element binding protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936601:2,470,021...2,616,451
Ensembl chrNW_004936601:2,470,036...2,610,942
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G |
Cps1 |
carbamoyl-phosphate synthase 1 |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936586:5,739,038...5,850,317
Ensembl chrNW_004936586:5,739,337...5,850,312
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G |
Crebbp |
CREB binding protein |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: LIVER CELL CARCINOMA |
ClinVar |
PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 PMID:23685749 PMID:23778141 PMID:26087898 PMID:26619011 PMID:27257180 PMID:28492532 PMID:28970362 PMID:29551561 PMID:33560380 More...
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NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617
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Crhbp |
corticotropin releasing hormone binding protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936549:64,866...78,272
Ensembl chrNW_004936549:64,866...78,272
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Crp |
C-reactive protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
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NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Csf1r |
colony stimulating factor 1 receptor |
exacerbates severity |
ISO |
mRNA:increased expression:liver (human) protein:increased expression: liver (human) protein:increased expression:liver (human) DNA:hypomethylation DNA:hypomethylation:promoter (human) |
RGD |
PMID:11412385 PMID:14969845 PMID:20551429 PMID:32724427 PMID:32760707 |
RGD:150524279 RGD:150524282 RGD:150524286 RGD:150524301 RGD:150524302 |
NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
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Csf2 |
colony stimulating factor 2 |
treatment |
ISO |
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RGD |
PMID:12731087 |
RGD:10450243 |
NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864
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Csk |
C-terminal Src kinase |
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ISO |
protein:decreased expression:liver |
RGD |
PMID:9918913 |
RGD:5134372 |
NCBI chrNW_004936471:33,757,778...33,777,871
Ensembl chrNW_004936471:33,757,772...33,778,933
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Csmd1 |
CUB and Sushi multiple domains 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936615:1,677,845...2,063,781
Ensembl chrNW_004936615:1,679,243...3,319,300
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Cspg4 |
chondroitin sulfate proteoglycan 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936471:34,438,676...34,475,005
Ensembl chrNW_004936471:34,438,676...34,475,052
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Csrnp1 |
cysteine and serine rich nuclear protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936473:28,398,528...28,409,962
Ensembl chrNW_004936473:28,398,543...28,409,962
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Ctla4 |
cytotoxic T-lymphocyte associated protein 4 |
susceptibility |
ISO |
DNA:SNPs: :rs231775,rs231725(human) protein:increased expression:CD4+ and CD8+ T cells: |
RGD |
PMID:23432218 PMID:28648905 |
RGD:14398741 RGD:14398742 |
NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643
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Ctnnb1 |
catenin beta 1 |
exacerbates susceptibility severity |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA DNA:missense mutations:exon 3:multiple (human) associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human) associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human) DNA:Mutations:exon: |
OMIM ClinVar RGD |
PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 PMID:10027390 PMID:10192393 PMID:10391090 PMID:10398436 PMID:10435629 PMID:10655994 PMID:10666372 PMID:11351304 PMID:11930117 PMID:11950921 PMID:12124804 PMID:15133491 PMID:19101982 PMID:19234609 PMID:21903672 PMID:23033978 PMID:23265383 PMID:24614104 PMID:24728327 PMID:24788118 PMID:25157968 PMID:25326635 PMID:25326669 PMID:25741868 PMID:26350204 PMID:26502894 PMID:26619011 PMID:26822237 PMID:26968103 PMID:27276713 PMID:27915094 PMID:27959697 PMID:28328801 PMID:28333917 PMID:28492532 PMID:28575650 PMID:29682453 PMID:30640974 PMID:31526516 More...
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RGD:14402039 RGD:14402040 RGD:14402052 RGD:150429592 |
NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
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Ctsd |
cathepsin D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936816:680,798...690,959
Ensembl chrNW_004936816:680,798...691,039
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Ctsl |
cathepsin L |
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ISO |
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RGD |
PMID:15641152 |
RGD:2315605 |
NCBI chrNW_004936680:3,047,355...3,050,640
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CUNH14orf180 |
chromosome unknown C14orf180 homolog |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936621:781,145...790,441
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Cux1 |
cut like homeobox 1 |
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ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:30561038 |
RGD:152985541 |
NCBI chrNW_004936543:1,482,606...1,781,294
Ensembl chrNW_004936543:1,485,970...1,796,070
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Cxcl10 |
C-X-C motif chemokine ligand 10 |
treatment disease_progression |
ISO |
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RGD |
PMID:27245433 PMID:28592115 PMID:28638480 |
RGD:27095889 RGD:27095898 RGD:27095899 |
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
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Cxcl11 |
C-X-C motif chemokine ligand 11 |
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ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:26569409 |
RGD:11344640 |
NCBI chrNW_004936676:72,383...73,697
Ensembl chrNW_004936676:71,667...73,738
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Cxcl12 |
C-X-C motif chemokine ligand 12 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 PMID:28284560 |
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NCBI chrNW_004936617:4,224,131...4,239,080
Ensembl chrNW_004936617:4,224,131...4,238,796
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Cxcl14 |
C-X-C motif chemokine ligand 14 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936597:2,746,415...2,754,169
Ensembl chrNW_004936597:2,746,296...2,754,716
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Cxcr4 |
C-X-C motif chemokine receptor 4 |
severity treatment |
ISO |
protein:increased expression:liver (human) human cells in mouse model |
RGD |
PMID:30034941 PMID:33574707 |
RGD:151665327 RGD:151665331 |
NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459
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Cyld |
CYLD lysine 63 deubiquitinase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21109933 |
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NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118
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Dab2ip |
DAB2 interacting protein |
severity |
ISO |
protein:decreased expression:liver (human) mRNA:decreased expression:liver (human) |
RGD |
PMID:22168621 PMID:31176165 |
RGD:151665110 RGD:151665148 |
NCBI chrNW_004936487:10,056,809...10,243,021
Ensembl chrNW_004936487:10,145,278...10,243,174
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Dbh |
dopamine beta-hydroxylase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936669:3,302,014...3,326,233
Ensembl chrNW_004936669:3,301,802...3,320,643
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Dcn |
decorin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936507:7,887,259...7,923,055
Ensembl chrNW_004936507:7,884,654...7,922,961
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Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
severity |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:33173221 |
RGD:151347691 |
NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833
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Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
disease_progression treatment |
ISO |
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RGD |
PMID:26362312 PMID:33969575 |
RGD:11086753 RGD:150429748 |
NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139
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Ddx3x |
DEAD-box helicase 3 X-linked |
sexual_dimorphism exacerbates |
ISO |
associated with hepatitis B; mRNA,protein:decreased expression:liver (human) |
RGD |
PMID:16301996 PMID:30297359 |
RGD:151356499 RGD:151356660 |
NCBI chrNW_004936502:7,770,896...7,820,555
Ensembl chrNW_004936502:7,804,824...7,820,569
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Depdc1 |
DEP domain containing 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936591:3,303,915...3,323,462
Ensembl chrNW_004936591:3,304,067...3,323,462
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Depdc1b |
DEP domain containing 1B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936480:7,750,244...7,841,556
Ensembl chrNW_004936480:7,750,241...7,841,536
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Depdc5 |
DEP domain containing 5, GATOR1 subcomplex subunit |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21725309 |
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NCBI chrNW_004936755:871,935...1,024,538
Ensembl chrNW_004936755:872,815...1,024,057
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Dhfr |
dihydrofolate reductase |
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ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
ClinVar |
PMID:28492532 |
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NCBI chrNW_004936469:67,962...83,116
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Dicer1 |
dicer 1, ribonuclease III |
susceptibility |
ISO |
associated with hepatitis B; DNA:SNP: :rs1057035 T>C (human) |
RGD |
PMID:23868705 |
RGD:149735346 |
NCBI chrNW_004936846:528,768...584,599
Ensembl chrNW_004936846:532,972...575,689
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Dipk2b |
divergent protein kinase domain 2B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936502:11,243,167...11,284,186
Ensembl chrNW_004936502:11,247,775...11,284,186
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Diras3 |
DIRAS family GTPase 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936591:3,688,774...3,691,342
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Dlgap5 |
DLG associated protein 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936697:8,001...20,724
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Dlk1 |
delta like non-canonical Notch ligand 1 |
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ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:26569409 |
RGD:11344640 |
NCBI chrNW_004936604:4,504,519...4,511,897
Ensembl chrNW_004936604:4,504,503...4,511,910
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Dmgdh |
dimethylglycine dehydrogenase |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936549:6,838,773...6,899,961
Ensembl chrNW_004936549:6,839,295...6,899,911
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Dnajc6 |
DnaJ heat shock protein family (Hsp40) member C6 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936692:2,788,477...2,836,094
Ensembl chrNW_004936692:2,741,632...2,834,078
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Dnase1l3 |
deoxyribonuclease 1L3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936473:8,430,235...8,495,170
Ensembl chrNW_004936473:8,430,231...8,457,469
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Dnmt1 |
DNA methyltransferase 1 |
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ISO |
mRNA, protein:increased expression:liver |
RGD |
PMID:11844796 |
RGD:2289670 |
NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416
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Dnmt3a |
DNA methyltransferase 3 alpha |
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ISO |
protein:increased expression:liver: mRNA, protein:increased expression:liver |
RGD |
PMID:11844796 PMID:15885882 |
RGD:2289670 RGD:9588598 |
NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610
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Dnmt3b |
DNA methyltransferase 3 beta |
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ISO |
mRNA, protein:increased expression:liver mRNA:increased expression:liver: |
RGD |
PMID:11844796 PMID:15885882 |
RGD:2289670 RGD:9588598 |
NCBI chrNW_004936485:19,547,836...19,570,716
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Dpyd |
dihydropyrimidine dehydrogenase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18019677 |
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NCBI chrNW_004936537:1,660,461...2,439,305
Ensembl chrNW_004936537:1,660,477...2,439,273
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Dsn1 |
DSN1 component of MIS12 kinetochore complex |
disease_progression |
ISO |
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RGD |
PMID:30136646 |
RGD:27372884 |
NCBI chrNW_004936561:4,322,709...4,337,405
Ensembl chrNW_004936561:4,322,675...4,337,506
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Dtl |
denticleless E3 ubiquitin protein ligase homolog |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936557:1,347,991...1,389,836
Ensembl chrNW_004936557:1,347,991...1,389,836
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Dynlrb1 |
dynein light chain roadblock-type 1 |
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ISO |
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RGD |
PMID:11750132 |
RGD:13208527 |
NCBI chrNW_004936561:6,118,849...6,135,001
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Dynlrb2 |
dynein light chain roadblock-type 2 |
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ISO |
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RGD |
PMID:11750132 |
RGD:13208527 |
NCBI chrNW_004936475:28,286,434...28,295,345
Ensembl chrNW_004936475:28,286,390...28,296,001
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E2f1 |
E2F transcription factor 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12029619 PMID:15565109 PMID:28284560 |
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NCBI chrNW_004936561:6,894,827...6,901,058
Ensembl chrNW_004936561:6,896,063...6,900,026
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E2f8 |
E2F transcription factor 8 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936654:322,863...339,365
Ensembl chrNW_004936654:322,863...338,699
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Eaf2 |
ELL associated factor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20564326 |
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NCBI chrNW_004936536:8,213,794...8,257,595
Ensembl chrNW_004936536:8,213,763...8,258,201
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Ecm1 |
extracellular matrix protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936580:750,423...756,765
Ensembl chrNW_004936580:750,736...756,771
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Ect2 |
epithelial cell transforming 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936703:5,744...45,636
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Eef2 |
eukaryotic translation elongation factor 2 |
exacerbates |
ISO |
protein:increased expression, increased phosphorylation:liver (human) |
RGD |
PMID:28060762 |
RGD:153298915 |
NCBI chrNW_004936588:2,259,236...2,267,692
Ensembl chrNW_004936588:2,258,309...2,266,609
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Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
disease_progression |
ISO |
protein:decreased expression:liver: |
RGD |
PMID:23936443 |
RGD:10401793 |
NCBI chrNW_004936491:2,159,654...2,214,480
Ensembl chrNW_004936491:2,159,096...2,214,677
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Eftud2 |
elongation factor Tu GTP binding domain containing 2 |
ameliorates severity |
ISO |
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RGD |
PMID:34282556 |
RGD:155791664 |
NCBI chrNW_004936541:1,216,584...1,259,355
Ensembl chrNW_004936541:1,217,138...1,257,935
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Egf |
epidermal growth factor |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human) associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human) |
CTD RGD |
PMID:9029167 PMID:18167406 PMID:23790025 |
RGD:14695013 RGD:14695014 |
NCBI chrNW_004936563:1,058,803...1,181,393
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Egfr |
epidermal growth factor receptor |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:9029167 PMID:11355950 |
RGD:126781769 |
NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
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Egr1 |
early growth response 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749
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Egr2 |
early growth response 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936753:1,958,250...1,962,640
Ensembl chrNW_004936753:1,958,264...1,962,640
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Ehd3 |
EH domain containing 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936493:1,864,836...1,896,079
Ensembl chrNW_004936493:1,864,755...1,896,097
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Eif3h |
eukaryotic translation initiation factor 3 subunit H |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14578863 |
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NCBI chrNW_004936470:29,509,154...29,606,124
Ensembl chrNW_004936470:29,509,151...29,606,124
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Enah |
ENAH actin regulator |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35030977 |
RGD:155791678 |
NCBI chrNW_004936526:2,332,344...2,477,827
Ensembl chrNW_004936526:2,332,664...2,477,833
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Eng |
endoglin |
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ISO |
protein:increased expression:liver (rat) |
RGD |
PMID:20368095 |
RGD:7257538 |
NCBI chrNW_004936487:15,467,165...15,499,180
Ensembl chrNW_004936487:15,467,835...15,477,488
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Eno1 |
enolase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183
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Ep300 |
E1A binding protein p300 |
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ISO |
protein:increased expression:liver (rat) |
RGD |
PMID:17083329 |
RGD:2312274 |
NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
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Epas1 |
endothelial PAS domain protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26735578 |
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NCBI chrNW_004936508:5,855,748...5,938,879
Ensembl chrNW_004936508:5,855,732...5,938,856
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Epcam |
epithelial cell adhesion molecule |
severity |
ISO |
protein:increased expression:liver |
RGD |
PMID:24616575 |
RGD:14695007 |
NCBI chrNW_004936508:5,019,513...5,032,610
Ensembl chrNW_004936508:5,019,918...5,032,414
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Ephb1 |
EPH receptor B1 |
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ISO |
protein:increased phosphorylation:liver (mouse) |
RGD |
PMID:28100771 |
RGD:127285675 |
NCBI chrNW_004936529:8,006,780...8,261,923
Ensembl chrNW_004936529:7,839,768...8,261,942
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G |
Ephx1 |
epoxide hydrolase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:7892276 |
|
NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286
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|
G |
Epo |
erythropoietin |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936543:742,722...745,332
Ensembl chrNW_004936543:743,537...745,343
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G |
Eps8l3 |
EPS8 signaling adaptor L3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936704:1,241,341...1,251,702
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
disease_progression |
ISO |
|
RGD |
PMID:11355950 |
RGD:126781769 |
NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
|
ISO |
DNA:insertion/deletion:3'UTR:rs6147150 (human) |
RGD |
PMID:22294845 |
RGD:126781763 |
NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
|
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:15922480 |
RGD:155598683 |
NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
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G |
Ercc2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
susceptibility disease_progression |
ISO |
DNA:SNPs:exon 23: p.K751Q (human) DNA:SNP:cd: 312A>G (human) DNA:SNPs:exon 23: p.K751Q (rs13181) (human) DNA:SNPs:exon 23: p.K751Q (human) |
RGD |
PMID:19919686 PMID:25531380 PMID:28598207 PMID:28927037 |
RGD:150530503 RGD:25671459 RGD:25671460 RGD:25671461 |
NCBI chrNW_004936706:1,816,561...1,829,638
Ensembl chrNW_004936706:1,816,571...1,829,692
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G |
Ereg |
epiregulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35776891 |
|
NCBI chrNW_004936598:1,328,803...1,336,141
Ensembl chrNW_004936598:1,328,803...1,344,360
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
|
ISO |
DNA:hypomethylation: CpG islands: |
RGD |
PMID:20165882 |
RGD:14694974 |
NCBI chrNW_004936541:4,613,197...4,705,911
Ensembl chrNW_004936541:4,617,555...4,705,866
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G |
Erp29 |
endoplasmic reticulum protein 29 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936558:4,531,397...4,538,943
Ensembl chrNW_004936558:4,531,471...4,538,943
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G |
Esm1 |
endothelial cell specific molecule 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936480:12,750,732...12,758,262
Ensembl chrNW_004936480:12,750,731...12,758,286
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G |
Esr1 |
estrogen receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 PMID:28284560 |
|
NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171
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G |
Etfa |
electron transfer flavoprotein subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936471:35,868,851...35,942,662
Ensembl chrNW_004936471:35,868,757...35,943,139
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G |
Exo1 |
exonuclease 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936526:8,570,488...8,627,004
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|
G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
susceptibility |
ISO |
mRNA:increased expression:liver (human) CTD Direct Evidence: marker/mechanism DNA:SNPs: :multiple |
RGD CTD |
PMID:24040354 PMID:24211739 PMID:25226601 PMID:26517514 PMID:28284560 PMID:34545456 More...
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RGD:10755339 RGD:11537550 RGD:126779595 RGD:126779608 |
NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939
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G |
F2 |
coagulation factor II, thrombin |
severity |
ISO |
CTD Direct Evidence: marker/mechanism associated with liver cirrhosis;protein:altered expression, altered processing:liver (human) |
CTD RGD |
PMID:2821104 PMID:7620113 |
RGD:14975114 |
NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650
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G |
Fabp5 |
fatty acid binding protein 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936656:2,881,552...2,886,192
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G |
Fam180a |
family with sequence similarity 180 member A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936592:501,764...514,153
Ensembl chrNW_004936592:500,440...514,238
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G |
Fam83d |
family with sequence similarity 83 member D |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936561:2,528,463...2,549,665
Ensembl chrNW_004936561:2,528,404...2,549,711
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G |
Fancd2 |
FA complementation group D2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936602:3,162,177...3,220,468
Ensembl chrNW_004936602:3,161,960...3,209,868
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G |
Fanci |
FA complementation group I |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936483:15,096,215...15,179,856
Ensembl chrNW_004936483:15,106,902...15,179,094
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G |
Fas |
Fas cell surface death receptor |
treatment |
ISO |
protein:increased expression:liver: |
RGD |
PMID:11274632 PMID:29634416 PMID:30737368 |
RGD:13792608 RGD:14700677 RGD:14700700 |
NCBI chrNW_004936735:209,369...234,582
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G |
Faslg |
Fas ligand |
|
ISO |
protein:increased expression:liver: |
RGD |
PMID:11274632 |
RGD:14700677 |
NCBI chrNW_004936481:14,789,547...14,795,780
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G |
Fasn |
fatty acid synthase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 PMID:15543204 PMID:21147110 |
|
NCBI chrNW_004936594:5,591,785...5,609,886
Ensembl chrNW_004936594:5,592,609...5,608,972
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G |
Fat1 |
FAT atypical cadherin 1 |
disease_progression |
ISO |
mRNA,protein:increased expression:liver (human) |
RGD |
PMID:24590895 |
RGD:151347630 |
NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823
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G |
Fate1 |
fetal and adult testis expressed 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15580283 |
|
NCBI chrNW_004936714:1,029,390...1,036,254
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G |
Fbp1 |
fructose-bisphosphatase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22039417 |
|
NCBI chrNW_004936626:3,555,835...3,581,651
Ensembl chrNW_004936626:3,555,762...3,581,659
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|
G |
Fbxl18 |
F-box and leucine rich repeat protein 18 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936765:679,643...721,379
Ensembl chrNW_004936765:679,554...721,411
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|
G |
Fbxo11 |
F-box protein 11 |
exacerbates ameliorates |
ISO |
mRNA:increased expression:liver (human) protein:increased expression:liver (human) |
RGD |
PMID:29518611 PMID:29603830 PMID:32657545 |
RGD:152025259 RGD:152025263 RGD:152025266 |
NCBI chrNW_004936508:4,622,695...4,708,694
Ensembl chrNW_004936508:4,685,595...4,708,694
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G |
Fcn3 |
ficolin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936474:11,680,166...11,685,214
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|
G |
Fdft1 |
farnesyl-diphosphate farnesyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
|
NCBI chrNW_004936628:3,599,435...3,600,061
|
|
G |
Fes |
FES proto-oncogene, tyrosine kinase |
exacerbates |
ISO |
DNA:hypermethylation:promoter (human) |
RGD |
PMID:31038805 |
RGD:153323297 |
NCBI chrNW_004936483:16,123,938...16,135,044
Ensembl chrNW_004936483:16,123,779...16,135,044
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|
G |
Fgf19 |
fibroblast growth factor 19 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25822088 |
|
NCBI chrNW_004936599:923,943...932,428
Ensembl chrNW_004936599:923,943...932,321
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|
G |
Fgf3 |
fibroblast growth factor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25822088 |
|
NCBI chrNW_004936599:868,634...875,464
Ensembl chrNW_004936599:868,634...875,464
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|
G |
Fgf4 |
fibroblast growth factor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25822088 |
|
NCBI chrNW_004936599:894,091...895,676
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|
G |
Fgfr1 |
fibroblast growth factor receptor 1 |
treatment |
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
RGD ClinVar |
PMID:21573021 PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156 |
RGD:25440476 |
NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
severity |
ISO |
associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human) |
RGD |
PMID:30952770 |
RGD:38501096 |
NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
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|
G |
Fgfr4 |
fibroblast growth factor receptor 4 |
treatment |
ISO |
|
RGD |
PMID:32677805 |
RGD:150520166 |
NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
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G |
Fh |
fumarate hydratase |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:10896297 PMID:15221078 PMID:16876016 PMID:17182618 PMID:18313410 PMID:19151755 PMID:20301679 PMID:21445611 PMID:25637381 PMID:25741868 PMID:28492532 PMID:28747166 More...
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NCBI chrNW_004936526:8,936,096...8,965,155
Ensembl chrNW_004936526:8,935,991...8,965,367
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G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
|
ISO |
|
RGD |
PMID:12112319 |
RGD:632723 |
NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506
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G |
Flt3 |
fms related receptor tyrosine kinase 3 |
ameliorates |
ISO |
human cells in mouse model |
RGD |
PMID:27511526 |
RGD:149735514 |
NCBI chrNW_004936472:23,169,967...23,239,178
Ensembl chrNW_004936472:23,170,470...23,256,904
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G |
Flvcr1 |
FLVCR choline and heme transporter 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936557:693,445...727,166
Ensembl chrNW_004936557:692,489...726,965
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9029167 PMID:28284560 |
|
NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122
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|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936706:1,900,954...1,907,567
Ensembl chrNW_004936706:1,900,931...1,906,772
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:30086463 PMID:32048611 |
RGD:153344517 RGD:153344521 |
NCBI chrNW_004936493:4,308,683...4,327,102
Ensembl chrNW_004936493:4,304,395...4,327,179
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G |
Foxa1 |
forkhead box A1 |
susceptibility sexual_dimorphism disease_progression |
ISO |
DNA:VNTR, SNPs, haplotypes:multiple: protein:decreased expression:liver |
RGD |
PMID:25965836 PMID:29208003 PMID:31400761 |
RGD:11054501 RGD:151665752 RGD:151665820 |
NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
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G |
Foxm1 |
forkhead box M1 |
|
ISO |
CTD Direct Evidence: marker/mechanism OMIM:114550 |
CTD MouseDO |
PMID:15082532 PMID:17173139 PMID:28284560 |
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NCBI chrNW_004936606:3,185,289...3,198,427
Ensembl chrNW_004936606:3,185,982...3,198,378
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G |
Foxo1 |
forkhead box O1 |
|
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:28972178 |
RGD:14401599 |
NCBI chrNW_004936565:5,210,014...5,299,213
Ensembl chrNW_004936565:5,210,014...5,302,436
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G |
Foxp1 |
forkhead box P1 |
treatment |
ISO |
|
RGD |
PMID:25156538 |
RGD:9587823 |
NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
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G |
Foxp3 |
forkhead box P3 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:21086571 |
RGD:38548919 |
NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
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G |
Fst |
follistatin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12203361 PMID:19363144 |
|
NCBI chrNW_004936480:13,990,967...13,997,248
Ensembl chrNW_004936480:13,990,929...13,997,248
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G |
Fth1 |
ferritin heavy chain 1 |
|
ISO |
mRNA:increased expression:liver (rat) |
RGD |
PMID:9054589 |
RGD:632698 |
NCBI chrNW_004936581:1,118,905...1,120,592
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G |
Fubp1 |
far upstream element binding protein 1 |
exacerbates ameliorates |
ISO |
mRNA:increased expression:liver (human) human cell line in a mouse model associated with Chronic Hepatitis C;mRNA:increased expression:liver (human) |
RGD |
PMID:19637194 PMID:25995247 PMID:31587040 |
RGD:151361188 RGD:151361194 RGD:151361196 |
NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
treatment |
ISO |
associated with Glycogen Storage Disease IA, human gene in a mouse model |
RGD |
PMID:28096054 |
RGD:14695537 |
NCBI chrNW_004936490:17,605,865...17,614,754
Ensembl chrNW_004936490:17,605,865...17,615,145
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:25473368 PMID:35693827 |
RGD:10449118 RGD:153344586 |
NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889
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G |
Gabrd |
gamma-aminobutyric acid type A receptor subunit delta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936737:1,400,437...1,405,885
Ensembl chrNW_004936737:1,400,395...1,406,119
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|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16767786 PMID:21472284 |
|
NCBI chrNW_004936709:1,243,149...1,247,782
Ensembl chrNW_004936709:1,243,147...1,247,903
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G |
Gc |
GC vitamin D binding protein |
susceptibility |
ISO |
protein:increased expression:liver associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human) |
RGD |
PMID:21683810 PMID:25541958 |
RGD:14402025 RGD:5509919 |
NCBI chrNW_004936598:3,220,029...3,256,091
Ensembl chrNW_004936598:3,219,991...3,261,629
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G |
Gdf15 |
growth differentiation factor 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20512989 |
|
NCBI chrNW_004936596:2,854,620...2,857,018
Ensembl chrNW_004936596:2,854,841...2,857,111
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|
G |
Gdf2 |
growth differentiation factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23936038 PMID:28284560 |
|
NCBI chrNW_004936554:7,307,461...7,322,048
Ensembl chrNW_004936554:7,316,435...7,322,060
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
disease_progression |
ISO |
HBV associated RNA,protein:increased expression, activity:liver: |
RGD |
PMID:10572675 PMID:11940314 PMID:27793641 |
RGD:14701040 RGD:14701041 RGD:14701048 |
NCBI chrNW_004936619:762,278...791,610
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G |
Ghr |
growth hormone receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936518:235,996...380,225
Ensembl chrNW_004936518:235,990...380,272
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G |
Gins1 |
GINS complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936620:421,845...446,853
Ensembl chrNW_004936620:422,230...446,753
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G |
Gjb1 |
gap junction protein beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17978847 |
|
NCBI chrNW_004936762:389,655...398,035
Ensembl chrNW_004936762:389,669...395,898
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G |
Gjb2 |
gap junction protein beta 2 |
|
ISO |
DNA, mRNA:promoter hypermethylation, decreased expression:liver |
RGD |
PMID:17295234 |
RGD:2289638 |
NCBI chrNW_004936720:1,528,205...1,530,296
Ensembl chrNW_004936720:1,528,249...1,528,929
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G |
Gli1 |
GLI family zinc finger 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26189965 |
|
NCBI chrNW_004936646:1,622,308...1,629,787
Ensembl chrNW_004936646:1,622,308...1,629,779
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G |
Glul |
glutamate-ammonia ligase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
|
NCBI chrNW_004936481:7,293,301...7,301,416
Ensembl chrNW_004936481:7,293,091...7,306,202
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G |
Gmnn |
geminin DNA replication inhibitor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936671:1,017,621...1,027,224
Ensembl chrNW_004936671:1,018,124...1,026,968
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G |
Gmps |
guanine monophosphate synthase |
|
ISO |
protein:increased activity:hepatoma (rat) |
RGD |
PMID:6861338 |
RGD:5135537 |
NCBI chrNW_004936519:3,094,763...3,143,322
Ensembl chrNW_004936519:3,104,701...3,141,549
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G |
Gnao1 |
G protein subunit alpha o1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936475:8,610,123...8,681,606
Ensembl chrNW_004936475:8,565,889...8,690,673
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G |
Gnaz |
G protein subunit alpha z |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936619:191,097...244,034
Ensembl chrNW_004936619:191,091...244,235
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G |
Gnmt |
glycine N-methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism OMIM:114550 |
CTD MouseDO |
PMID:19146867 PMID:31086990 |
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NCBI chrNW_004936476:16,961,734...16,965,487
Ensembl chrNW_004936476:16,957,270...16,965,346
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G |
Golm1 |
golgi membrane protein 1 |
severity |
ISO |
mRNA, protein:increased expression:liver protein:increased expression:serum |
RGD |
PMID:21140449 PMID:21443671 |
RGD:401827118 RGD:401827119 |
NCBI chrNW_004936680:1,463,991...1,528,322
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G |
Gpc1 |
glypican 1 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936745:1,118,732...1,127,169
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G |
Gpc3 |
glypican 3 |
severity exacerbates disease_progression treatment |
ISO |
protein:increased expression:serum protein:increased expression:blood serum (human) mRNA,protein:increased expression:peripheral blood mononuclear cell,blood serum, liver (human) protein:increased expression:liver (human) mRNA:increased expression:Peripheral Blood (human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:16698587 PMID:19496787 PMID:21438004 PMID:22883669 PMID:23558072 PMID:25449037 PMID:27286460 PMID:28284560 PMID:28801286 More...
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RGD:14695019 RGD:14695020 RGD:243065125 RGD:243065131 RGD:243065134 RGD:243065135 RGD:243065139 |
NCBI chrNW_004936691:1,060,013...1,459,736
Ensembl chrNW_004936691:1,059,994...1,459,740
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G |
Gpm6a |
glycoprotein M6A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936516:6,339,058...6,647,412
Ensembl chrNW_004936516:6,338,819...6,481,425
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G |
Gpr158 |
G protein-coupled receptor 158 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936484:835,886...1,224,450
Ensembl chrNW_004936484:836,700...1,226,162
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G |
Gpr182 |
G protein-coupled receptor 182 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936646:1,210,711...1,212,746
Ensembl chrNW_004936646:1,210,757...1,212,425
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G |
Gpx1 |
glutathione peroxidase 1 |
severity no_association susceptibility |
ISO |
associated with hepatitis C;DNA:missense mutation:CDS:p.P198L (rs1050450) (human) DNA:missense mutation:CDS:p.P198L (human) associated with alcoholic liver cirrhosis;DNA:missense mutation:CDS:p.P198L (human) |
RGD |
PMID:16510607 PMID:19929244 PMID:25894370 PMID:26990426 |
RGD:11533013 RGD:151708729 RGD:152995483 RGD:152998906 |
NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987
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G |
Gpx3 |
glutathione peroxidase 3 |
severity disease_progression |
ISO |
mRNA,protein:decreased expression:liver, blood plasma (human) DNA:hypermethylation |
RGD |
PMID:25333265 PMID:25445749 PMID:27570561 |
RGD:151665355 RGD:151665509 RGD:401827855 |
NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
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G |
Grb7 |
growth factor receptor bound protein 7 |
exacerbates |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:17634422 |
RGD:151347655 |
NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337
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G |
Gstp1 |
glutathione S-transferase pi 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism DNA:increased methylation:promoter |
CTD RGD |
PMID:9029167 PMID:22536438 |
RGD:14401712 |
NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050
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G |
Gtse1 |
G2 and S-phase expressed 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936629:3,590,101...3,607,625
Ensembl chrNW_004936629:3,592,100...3,607,754
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G |
Gys2 |
glycogen synthase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936548:5,256,185...5,309,758
Ensembl chrNW_004936548:5,256,437...5,309,758
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G |
Hamp |
hepcidin antimicrobial peptide |
|
ISO |
DNA:hypermethylation,hypomethylation:promoter CTD Direct Evidence: marker/mechanism mRNA:decreased expression:liver (human) |
RGD CTD |
PMID:28284560 PMID:29235098 |
RGD:15042879 |
NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686
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G |
Hao2 |
hydroxyacid oxidase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936627:4,167,501...4,179,596
Ensembl chrNW_004936627:4,159,214...4,179,806
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936515:6,030,402...6,051,161
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G |
Havcr2 |
hepatitis A virus cellular receptor 2 |
disease_progression |
ISO |
associated with hepatitis B;DNA:SNP: : ���1516 G>T (human) |
RGD |
PMID:27034168 |
RGD:40818257 |
NCBI chrNW_004936515:6,001,324...6,015,407
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G |
Hdac2 |
histone deacetylase 2 |
disease_progression |
ISO |
mRNA:increased expression:liver: |
RGD |
PMID:24448241 |
RGD:9590206 |
NCBI chrNW_004936679:2,448,676...2,474,641
Ensembl chrNW_004936679:2,448,390...2,474,641
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G |
Hdac4 |
histone deacetylase 4 |
|
ISO |
mRNA:increased expression:liver: |
RGD |
PMID:21837748 |
RGD:9681451 |
NCBI chrNW_004936745:1,730,743...1,942,071
Ensembl chrNW_004936745:1,730,694...1,942,074
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G |
Herc5 |
HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28919514 |
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NCBI chrNW_004936685:917,019...966,814
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G |
Hfe |
homeostatic iron regulator |
disease_progression |
ISO |
associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human) |
RGD |
PMID:20019189 PMID:29642405 |
RGD:14746967 RGD:2317357 |
NCBI chrNW_004936671:1,940,079...1,947,574
Ensembl chrNW_004936671:1,940,101...1,947,580
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G |
Hgf |
hepatocyte growth factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9932610 PMID:11896611 |
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NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779
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G |
Hgfac |
HGF activator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
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NCBI chrNW_004936477:20,291,791...20,298,764
Ensembl chrNW_004936477:20,291,852...20,298,764
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G |
Hhip |
hedgehog interacting protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18559595 |
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NCBI chrNW_004936535:4,210,305...4,305,930
Ensembl chrNW_004936535:4,210,305...4,305,930
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
treatment disease_progression |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:19335982 PMID:26078356 PMID:31321740 |
RGD:11526468 RGD:155882550 RGD:9068886 |
NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157
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G |
Hilpda |
hypoxia inducible lipid droplet associated |
disease_progression |
ISO |
mRNA:increased expression:liver (human) mRNA, protein:increased expression:liver (human) human cells in mouse model |
RGD |
PMID:30205391 PMID:31142329 PMID:35693827 |
RGD:153344574 RGD:153344577 RGD:153344586 |
NCBI chrNW_004936479:15,582,260...15,583,213
Ensembl chrNW_004936479:15,582,260...15,607,428
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G |
Hjurp |
Holliday junction recognition protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936525:3,528,379...3,544,088
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G |
Hmgb2 |
high mobility group box 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20851854 |
|
NCBI chrNW_004936516:4,536,664...4,539,331
Ensembl chrNW_004936516:4,534,306...4,539,387
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9207284 PMID:21147110 |
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NCBI chrNW_004936549:1,378,536...1,400,501
Ensembl chrNW_004936549:1,378,736...1,400,532
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
disease_progression |
ISO |
|
RGD |
PMID:28867541 |
RGD:14975299 |
NCBI chrNW_004936627:4,451,847...4,473,163
Ensembl chrNW_004936627:4,451,823...4,473,223
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G |
Hmmr |
hyaluronan mediated motility receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936515:570,112...599,400
Ensembl chrNW_004936515:571,139...600,132
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G |
Hnf1a |
HNF1 homeobox A |
treatment |
ISO |
human cell line in mouse model |
RGD |
PMID:29466992 |
RGD:14700664 |
NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505
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G |
Hnf4a |
hepatocyte nuclear factor 4 alpha |
|
ISO |
protein:decreased expression:liver: |
RGD |
PMID:20876809 |
RGD:12904747 |
NCBI chrNW_004936530:2,401,053...2,425,989
Ensembl chrNW_004936530:2,401,043...2,454,466
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
|
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:23633480 |
RGD:9685423 |
NCBI chrNW_004936512:11,481,017...11,487,737
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
|
ISO |
mRNA:increased expression:liver (rat) protein:increased expression:liver (human) |
RGD |
PMID:20604928 PMID:23633480 |
RGD:9685422 RGD:9685423 |
NCBI chrNW_004936478:2,970,261...2,980,277
Ensembl chrNW_004936478:2,970,468...2,980,381
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G |
Hnrnpab |
heterogeneous nuclear ribonucleoprotein A/B |
severity |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:24638979 |
RGD:10059322 |
NCBI chrNW_004936647:478,445...520,361
Ensembl chrNW_004936647:478,443...484,570
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G |
Hnrnpd |
heterogeneous nuclear ribonucleoprotein D |
|
ISO |
protein:increased expression:liver (rat) protein:increased expression:liver (human) |
RGD |
PMID:20102719 PMID:22318685 |
RGD:10042969 RGD:10042977 |
NCBI chrNW_004936738:2,096,370...2,115,135
Ensembl chrNW_004936738:2,096,370...2,113,604
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
|
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:23633480 |
RGD:9685423 |
NCBI chrNW_004936739:1,135,282...1,144,643
Ensembl chrNW_004936739:1,135,289...1,144,643
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G |
Hnrnpl |
heterogeneous nuclear ribonucleoprotein L |
|
ISO |
associated with Hepatitis B |
RGD |
PMID:24125732 |
RGD:9999429 |
NCBI chrNW_004936661:1,793,791...1,806,564
Ensembl chrNW_004936661:1,793,801...1,806,579
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G |
Hoxa10 |
homeobox A10 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936478:3,798,679...3,802,007
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G |
Hoxa13 |
homeobox A13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936478:3,824,715...3,827,277
Ensembl chrNW_004936478:3,824,715...3,827,277
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G |
Hoxd9 |
homeobox D9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936509:5,609,744...5,611,943
Ensembl chrNW_004936509:5,609,744...5,611,943
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
|
ISO |
protein:increased activity:hepatoma (rat) |
RGD |
PMID:6327016 |
RGD:5135035 |
NCBI chrNW_004936691:650,753...694,362
Ensembl chrNW_004936691:652,769...694,463
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G |
Hras |
HRas proto-oncogene, GTPase |
treatment |
ISO |
human cells in a mouse model ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
RGD ClinVar |
PMID:10791191 PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17601930 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20937837 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22420426 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25815234 PMID:25914166 PMID:26467025 PMID:26619011 PMID:26778095 PMID:27195699 PMID:27283355 PMID:27444071 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:30055033 PMID:30138938 PMID:30191474 PMID:31394527 PMID:31560489 PMID:31564432 PMID:31775759 PMID:32371413 PMID:32732226 PMID:33027564 PMID:33372952 PMID:34008892 PMID:34958143 PMID:168335863 More...
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RGD:14688055 |
NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 PMID:29698666 |
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NCBI chrNW_004936487:13,348,465...13,352,717
Ensembl chrNW_004936487:13,348,465...13,352,717
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936531:7,702,186...7,716,428
Ensembl chrNW_004936531:7,702,695...7,716,380
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:16799960 |
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NCBI chrNW_004936654:1,315,921...1,332,926
Ensembl chrNW_004936654:1,315,862...1,333,005
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G |
Htra1 |
HtrA serine peptidase 1 |
exacerbates disease_progression |
ISO |
protein:decreased expression:liver (human) mRNA:decreased expression:liver (human) |
RGD |
PMID:20943460 PMID:26403966 |
RGD:152985524 RGD:152985529 |
NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739
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G |
Icam1 |
intercellular adhesion molecule 1 |
severity |
ISO |
protein:increased expression:serum |
RGD |
PMID:26109813 |
RGD:11056752 |
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
ClinVar |
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 PMID:21352804 PMID:21446021 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22898539 PMID:23558169 PMID:24606448 PMID:25043048 PMID:25157968 PMID:25741868 PMID:26619011 PMID:27993330 PMID:30231226 PMID:36201590 More...
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NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
disease_progression |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
RGD ClinVar |
PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22616558 PMID:22898539 PMID:23949315 PMID:24606448 PMID:24716838 PMID:25157968 PMID:26619011 More...
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RGD:14985249 |
NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
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G |
Ier2 |
immediate early response 2 |
|
ISO |
human cells in mouse model |
RGD |
PMID:32009420 |
RGD:153323326 |
NCBI chrNW_004936659:2,176,962...2,179,900
Ensembl chrNW_004936659:2,178,312...2,178,983
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G |
Ifng |
interferon gamma |
|
ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:26569409 |
RGD:11344640 |
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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G |
Igbp1 |
immunoglobulin binding protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21339737 |
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NCBI chrNW_004936762:1,292,572...1,319,145
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G |
Igf1 |
insulin like growth factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
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G |
Igf1r |
insulin like growth factor 1 receptor |
susceptibility |
ISO |
DNA:SNPs, haplotype: : CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:17441810 PMID:23958494 PMID:24758241 |
RGD:14985227 |
NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925
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G |
Igf2 |
insulin like growth factor 2 |
susceptibility |
ISO |
associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:12532445 PMID:16092956 PMID:16750516 PMID:17554210 |
RGD:14401723 RGD:2311523 |
NCBI chrNW_004936816:972,902...981,232
Ensembl chrNW_004936816:972,282...979,167
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G |
Igf2bp1 |
insulin like growth factor 2 mRNA binding protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936490:12,430,343...12,468,794
Ensembl chrNW_004936490:12,430,008...12,469,083
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G |
Igf2bp3 |
insulin like growth factor 2 mRNA binding protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936478:456,369...595,705
Ensembl chrNW_004936478:458,871...595,742
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G |
Igf2r |
insulin like growth factor 2 receptor |
no_association treatment disease_progression |
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma DNA:loss of heterozygosity,mutations:liver: DNA:loss of heterozygosity:liver |
OMIM ClinVar RGD |
PMID:9722161 PMID:10347113 PMID:18322954 PMID:25741868 PMID:30720132 |
RGD:14985219 RGD:14985220 RGD:14985221 |
NCBI chrNW_004936489:11,447,043...11,523,695
Ensembl chrNW_004936489:11,447,038...11,524,174
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Igfals |
insulin like growth factor binding protein acid labile subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936694:2,205,294...2,207,343
Ensembl chrNW_004936694:2,204,182...2,207,328
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
treatment |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:17292824 PMID:22176836 PMID:22922425 PMID:24971483 PMID:25173965 PMID:29551768 More...
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RGD:11079569 RGD:153297807 RGD:153297813 RGD:153305943 RGD:153305945 RGD:153305947 |
NCBI chrNW_004936809:1,280,254...1,306,964
Ensembl chrNW_004936809:1,257,654...1,301,813
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Ikzf1 |
IKAROS family zinc finger 1 |
ameliorates |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:25301737 |
RGD:150540326 |
NCBI chrNW_004936686:1,459,582...1,556,478
Ensembl chrNW_004936686:1,462,145...1,556,451
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Il10 |
interleukin 10 |
treatment |
ISO |
|
RGD |
PMID:23822114 PMID:26890368 |
RGD:14975171 RGD:7365006 |
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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Il12a |
interleukin 12A |
susceptibility |
ISO |
associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human) associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human) |
RGD |
PMID:20521253 PMID:26631030 PMID:27819525 |
RGD:25440490 RGD:25440491 RGD:25440501 |
NCBI chrNW_004936519:6,166,060...6,180,652
Ensembl chrNW_004936519:6,175,261...6,180,396
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Il15ra |
interleukin 15 receptor subunit alpha |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936484:8,590,945...8,623,478
Ensembl chrNW_004936484:8,590,482...8,623,469
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G |
Il18 |
interleukin 18 |
susceptibility disease_progression severity |
ISO |
DNA:SNP:promoter:-137G>C(rs187238)(human) associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human) associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human) |
RGD |
PMID:26893476 PMID:27429592 PMID:27470888 PMID:29341496 |
RGD:11538094 RGD:14695526 RGD:14695540 RGD:14696663 |
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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Il18r1 |
interleukin 18 receptor 1 |
|
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:26893476 |
RGD:11538094 |
NCBI chrNW_004936713:1,038,985...1,075,770
Ensembl chrNW_004936713:1,038,877...1,075,811
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Il1b |
interleukin 1 beta |
susceptibility |
ISO |
DNA:polymorphism:promoter:-31T>C (human) |
RGD |
PMID:21653279 |
RGD:7401222 |
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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G |
Il1rap |
interleukin 1 receptor accessory protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004937049:48,267...185,766
Ensembl chrNW_004937049:48,274...181,281
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G |
Il1rn |
interleukin 1 receptor antagonist |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
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G |
Il2 |
interleukin 2 |
treatment |
ISO |
|
RGD |
PMID:9449371 PMID:10933975 |
RGD:14747035 RGD:8693323 |
NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625
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G |
Il21 |
interleukin 21 |
|
ISO |
associated with hepatitis B;DNA:SNPS, haplotype:(rs13143866, rs2221903, rs907715) (human) |
RGD |
PMID:25892873 |
RGD:127285359 |
NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883
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G |
Il6 |
interleukin 6 |
disease_progression treatment |
ISO |
CTD Direct Evidence: marker/mechanism mRNA,protein:increased expression:liver, blood serum (mouse) DNA:SNP: :rs2069852 (human) |
CTD RGD |
PMID:17615358 PMID:20818158 PMID:26297436 PMID:26569409 PMID:27022031 PMID:27368337 More...
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RGD:11344640 RGD:14975289 |
NCBI chrNW_004936549:7,015,595...7,016,246
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G |
Il6st |
interleukin 6 cytokine family signal transducer |
|
ISO |
|
RGD |
PMID:15780071 |
RGD:1626706 |
NCBI chrNW_004936480:11,867,573...11,913,563
Ensembl chrNW_004936480:11,884,582...11,909,635
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G |
Ing3 |
inhibitor of growth family member 3 |
treatment |
ISO |
|
RGD |
PMID:25156538 |
RGD:9587823 |
NCBI chrNW_004936605:4,154,276...4,179,627
Ensembl chrNW_004936605:4,151,202...4,179,689
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G |
Inmt |
indolethylamine N-methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936478:6,997,605...7,002,649
Ensembl chrNW_004936478:6,997,549...7,002,666
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase type II B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29415082 |
|
NCBI chrNW_004936535:5,427,131...6,168,622
Ensembl chrNW_004936535:5,794,135...6,171,072
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G |
Ins |
insulin |
|
ISO |
associated with Chronic Hepatitis C;mRNA:decreased expression:liver (human) |
RGD |
PMID:33132693 |
RGD:150340613 |
NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357
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G |
Insr |
insulin receptor |
|
ISO |
human cells in a mouse model mRNA, protein:increased expression:liver (human, rat) |
RGD |
PMID:23633480 PMID:29610518 |
RGD:14700930 RGD:9685423 |
NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20977743 |
|
NCBI chrNW_004936483:16,489,127...16,594,712
Ensembl chrNW_004936483:16,489,133...16,594,783
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G |
Iqgap2 |
IQ motif containing GTPase activating protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism OMIM:114550 |
CTD MouseDO |
PMID:20977743 |
|
NCBI chrNW_004936549:256,097...541,860
Ensembl chrNW_004936549:255,303...541,917
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G |
Iqgap3 |
IQ motif containing GTPase activating protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936580:5,712,118...5,751,721
Ensembl chrNW_004936580:5,713,156...5,751,721
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G |
Irf2 |
interferon regulatory factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22561517 |
|
NCBI chrNW_004936554:4,706,688...4,793,236
Ensembl chrNW_004936554:4,706,650...4,793,701
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G |
Irs1 |
insulin receptor substrate 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:1311924 PMID:23958494 |
|
NCBI chrNW_004936525:9,064,442...9,125,972
Ensembl chrNW_004936525:9,064,466...9,122,635
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G |
Irs2 |
insulin receptor substrate 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16127164 |
|
NCBI chrNW_004936472:2,772,187...2,796,398
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G |
Isg15 |
ISG15 ubiquitin like modifier |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28919514 |
|
NCBI chrNW_004936737:2,043,383...2,044,761
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G |
Itih3 |
inter-alpha-trypsin inhibitor heavy chain 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
|
NCBI chrNW_004936473:3,553,210...3,568,636
Ensembl chrNW_004936473:3,553,210...3,568,636
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G |
Itih4 |
inter-alpha-trypsin inhibitor heavy chain 4 |
disease_progression |
ISO |
associated with hepatitis B;protein:decreased expression:serum |
RGD |
PMID:24836184 |
RGD:40903002 |
NCBI chrNW_004936473:3,573,282...3,589,345
Ensembl chrNW_004936473:3,573,384...3,589,345
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G |
Jag1 |
jagged canonical Notch ligand 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:30660174 |
RGD:14694832 |
NCBI chrNW_004936485:8,857,688...8,894,270
Ensembl chrNW_004936485:8,857,669...8,895,315
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G |
Jak1 |
Janus kinase 1 |
|
ISO |
|
RGD |
PMID:23788652 |
RGD:150524353 |
NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132
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G |
Jak2 |
Janus kinase 2 |
severity treatment ameliorates exacerbates |
ISO |
mRNA:decreased expression:liver (human) L-JAK2 KO protein:increased phosphorylation:liver (mouse) associated with Diseases of the Aged and non-alcoholic fatty liver disease protein:increased phosphorylation:liver (human) |
RGD |
PMID:22392353 PMID:22821478 PMID:25420511 PMID:28100771 PMID:29486150 PMID:31393852 More...
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RGD:125097525 RGD:127285621 RGD:127285655 RGD:127285672 RGD:127285675 RGD:18182928 |
NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
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G |
Jdp2 |
Jun dimerization protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20214788 |
|
NCBI chrNW_004936488:4,523,879...4,553,028
Ensembl chrNW_004936488:4,523,888...4,553,117
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20214788 |
|
NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350
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G |
Kat2b |
lysine acetyltransferase 2B |
severity |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:23643089 |
RGD:9590314 |
NCBI chrNW_004936473:12,341,545...12,415,637
Ensembl chrNW_004936473:12,344,343...12,417,875
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G |
Kbtbd11 |
kelch repeat and BTB domain containing 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936615:1,120,512...1,127,488
Ensembl chrNW_004936615:1,130,826...1,132,754
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G |
Kcnh1 |
potassium voltage-gated channel subfamily H member 1 |
|
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:17022810 |
RGD:9693723 |
NCBI chrNW_004936557:2,133,596...2,493,170
Ensembl chrNW_004936557:2,133,564...2,493,155
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G |
Kcnn2 |
potassium calcium-activated channel subfamily N member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004937043:133,981...269,593
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G |
Kdm1a |
lysine demethylase 1A |
severity |
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:23236241 |
RGD:9681002 |
NCBI chrNW_004936474:8,262,913...8,319,089
Ensembl chrNW_004936474:8,262,885...8,319,092
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G |
Kdm3a |
lysine demethylase 3A |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:21607773 |
RGD:9590222 |
NCBI chrNW_004936712:1,053,210...1,097,845
Ensembl chrNW_004936712:1,053,210...1,096,961
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Kdm5c |
lysine demethylase 5C |
exacerbates |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:26503415 |
RGD:11530160 |
NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966
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G |
Kdm6a |
lysine demethylase 6A |
ameliorates |
ISO |
human cells in a mouse model |
RGD |
PMID:32765772 |
RGD:150429729 |
NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
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Kdm8 |
lysine demethylase 8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936501:10,932,541...10,955,772
Ensembl chrNW_004936501:10,933,671...10,951,707
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G |
Kdr |
kinase insert domain receptor |
disease_progression treatment |
ISO |
protein:increased expression:liver associated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human) protein:decreased expression:liver DNA:SNPs: :rs1870377, rs2071559, rs2305948 (human) |
RGD |
PMID:19177438 PMID:23660204 PMID:24445728 PMID:25182707 PMID:25333267 |
RGD:126848806 RGD:126848810 RGD:126848812 RGD:126848813 RGD:126848814 |
NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002
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Kif11 |
kinesin family member 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936601:2,163,316...2,213,674
Ensembl chrNW_004936601:2,163,795...2,213,588
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G |
Kif14 |
kinesin family member 14 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936567:3,704,672...3,764,111
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G |
Kif15 |
kinesin family member 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936695:861,324...919,368
Ensembl chrNW_004936695:861,550...919,368
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G |
Kif18a |
kinesin family member 18A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936533:9,173,739...9,242,928
Ensembl chrNW_004936533:9,173,715...9,239,931
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G |
Kif18b |
kinesin family member 18B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936541:1,285,137...1,304,179
Ensembl chrNW_004936541:1,285,661...1,295,458
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G |
Kif1b |
kinesin family member 1B |
susceptibility severity |
ISO |
DNA:snp:intron:c.2537+518A>G (rs17401966) (human) mRNA, protein:decreased expression:liver (human) |
RGD |
PMID:26217094 PMID:27122668 |
RGD:11052488 RGD:12738461 |
NCBI chrNW_004936623:4,091,093...4,222,510
Ensembl chrNW_004936623:4,091,190...4,218,251
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Kif20a |
kinesin family member 20A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936531:7,361,928...7,371,397
Ensembl chrNW_004936531:7,361,928...7,374,789
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G |
Kif23 |
kinesin family member 23 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936471:29,154,618...29,177,865
Ensembl chrNW_004936471:29,150,205...29,177,769
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G |
Kif2c |
kinesin family member 2C |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936474:25,967,095...26,000,678
Ensembl chrNW_004936474:25,978,707...26,000,140
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G |
Kif4a |
kinesin family member 4A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936762:1,062,570...1,194,192
Ensembl chrNW_004936762:1,061,526...1,187,863
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G |
Kifc1 |
kinesin family member C1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936476:25,488,426...25,503,135
Ensembl chrNW_004936476:25,487,503...25,546,359
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G |
Klf4 |
KLF transcription factor 4 |
disease_progression treatment |
ISO |
|
RGD |
PMID:22677193 |
RGD:14402023 |
NCBI chrNW_004936559:5,105,456...5,109,970
Ensembl chrNW_004936559:5,105,463...5,109,970
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G |
Kmt2a |
lysine methyltransferase 2A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22634756 |
|
NCBI chrNW_004936542:3,480,071...3,566,823
Ensembl chrNW_004936542:3,391,774...3,562,147
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G |
Kmt2b |
lysine methyltransferase 2B |
|
ISO |
CTD Direct Evidence: marker/mechanism DNA:insertions, translocations:intron:IVS3, multiple (human) |
CTD RGD |
PMID:18320596 PMID:22634754 |
RGD:9588597 |
NCBI chrNW_004936570:583,616...605,846
Ensembl chrNW_004936570:583,616...605,603
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G |
Kmt2c |
lysine methyltransferase 2C |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22634756 |
|
NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365
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Kras |
KRAS proto-oncogene, GTPase |
induced |
ISO |
aflatoxin B1 induced:DNA:transversion,transition mutations:cds: ClinVar Annotator: match by term: Hepatocellular cancer |
RGD ClinVar |
PMID:2278970 PMID:3122217 PMID:8446626 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16434492 PMID:16618717 PMID:18316791 PMID:18794081 PMID:19075190 PMID:19114683 PMID:19679400 PMID:20921462 PMID:20921465 PMID:21228335 PMID:22407852 PMID:22722830 PMID:23325582 PMID:25157968 PMID:26619011 PMID:30891959 More...
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RGD:11568697 |
NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
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Krt18 |
keratin 18 |
|
ISO |
OMIM:114550 |
MouseDO |
|
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NCBI chrNW_004936512:10,290,706...10,294,647
Ensembl chrNW_004936512:10,290,690...10,294,651
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G |
Lcat |
lecithin-cholesterol acyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248
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G |
Lect2 |
leukocyte cell derived chemotaxin 2 |
ameliorates |
ISO |
human cells in mouse model protein:increased expression:blood serum (human) protein:increased expression:blood serum (mouse) |
RGD |
PMID:21394108 PMID:24892551 |
RGD:153323333 RGD:153323335 |
NCBI chrNW_004936597:3,051,143...3,057,383
Ensembl chrNW_004936597:3,051,143...3,057,383
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Lep |
leptin |
susceptibility severity |
ISO |
DNA:SNP:enhancer:-2548G>A (rs7799039) (human) protein:increased expression:liver (human) |
RGD |
PMID:18573568 PMID:28452232 |
RGD:15039399 RGD:25330348 |
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
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Lepr |
leptin receptor |
susceptibility |
ISO |
associated with Hepatitis B, Chronic;DNA:missense mutations:cds:p.Q223R, p.K109R (human) |
RGD |
PMID:23090836 |
RGD:21079466 |
NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444
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Letm1 |
leucine zipper and EF-hand containing transmembrane protein 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:23392203 |
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NCBI chrNW_004936477:21,550,104...21,589,662
Ensembl chrNW_004936477:21,550,013...21,587,007
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Lifr |
LIF receptor subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936518:3,651,630...3,693,072
Ensembl chrNW_004936518:3,652,152...3,693,078
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G |
LOC101954516 |
signal transducer and activator of transcription 5B |
exacerbates ameliorates |
ISO |
protein:increased expression:liver (human) mRNA:increased expression:liver (human) |
RGD |
PMID:17047057 PMID:31485610 |
RGD:153298929 RGD:153298932 |
NCBI chrNW_004936490:17,022,268...17,043,751
Ensembl chrNW_004936490:17,021,051...17,043,941
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G |
LOC101958515 |
apolipoprotein F |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936646:764,689...766,265
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G |
LOC101958908 |
HLA class II histocompatibility antigen, DP alpha 1 chain |
|
ISO |
DNA:hypomethylation: CpG islands: |
RGD |
PMID:20165882 |
RGD:14694974 |
NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907
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G |
LOC101959212 |
alpha-2-macroglobulin |
|
ISO |
CTD Direct Evidence: marker/mechanism mRNA,protein:increased expression:liver: |
CTD RGD |
PMID:15509519 |
RGD:1358261 |
NCBI chrNW_004936870:424,832...468,303
Ensembl chrNW_004936870:424,951...468,167
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G |
LOC101959495 |
PZP alpha-2-macroglobulin like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936870:497,071...542,364
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G |
LOC101964209 |
C-C chemokine receptor type 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16284949 |
|
NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186
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G |
LOC101964451 |
urocanate hydratase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936898:583,802...600,305
Ensembl chrNW_004936898:584,157...600,305
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G |
LOC101964975 |
interleukin-8 |
disease_progression susceptibility |
ISO |
protein:increased expression:liver (human) CTD Direct Evidence: marker/mechanism|therapeutic DNA:SNPs, haplotype:multiple mRNA:increased expression:liver (human) |
RGD CTD |
PMID:12432545 PMID:24381110 PMID:26078356 PMID:30523154 PMID:35776891 |
RGD:11526468 RGD:26884364 RGD:26884366 |
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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G |
LOC101968921 |
angiotensin-converting enzyme |
susceptibility |
ISO |
CTD Direct Evidence: therapeutic DNA:insertion/deletion:intron 16: |
CTD RGD |
PMID:16328049 PMID:25208933 |
RGD:11343535 |
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
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G |
LOC101969148 |
cytochrome P450 1A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15341023 |
|
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
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G |
LOC101969421 |
cytochrome P450 1A2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484
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G |
LOC101969650 |
cytochrome c oxidase subunit 7B2, mitochondrial |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936482:12,950,597...12,951,029
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LOC101970767 |
steroid 17-alpha-hydroxylase/17,20 lyase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15341023 |
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NCBI chrNW_004936600:3,097,620...3,102,713
Ensembl chrNW_004936600:3,097,638...3,102,713
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G |
LOC101971027 |
neuroendocrine secretory protein 55 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 PMID:7739708 PMID:8766942 PMID:9626141 PMID:10571700 PMID:11093740 PMID:12727968 PMID:12970318 PMID:15126527 PMID:15952988 PMID:16507630 PMID:16543670 PMID:17873334 PMID:20197676 PMID:21835143 PMID:23403822 PMID:23536913 PMID:23843956 PMID:24855271 PMID:25157968 PMID:25719192 PMID:25741868 PMID:26341786 PMID:26574629 PMID:26619011 PMID:27398169 PMID:27506760 PMID:28492532 PMID:29991465 PMID:30702195 More...
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NCBI chrNW_004936530:1,353,432...1,407,437
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LOC101971919 |
S-methylmethionine--homocysteine S-methyltransferase BHMT2 |
severity |
ISO |
mRNA:altered expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936549:6,900,075...6,914,217
Ensembl chrNW_004936549:6,899,948...6,914,263
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G |
LOC101972215 |
betaine--homocysteine S-methyltransferase 1 |
disease_progression |
ISO |
associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936549:6,938,100...6,956,380
Ensembl chrNW_004936549:6,938,092...6,957,363
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G |
LOC101972335 |
24-hydroxycholesterol 7-alpha-hydroxylase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936476:13,697,598...13,819,362
Ensembl chrNW_004936476:13,697,583...13,819,109
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G |
LOC101973029 |
cytochrome P450 2E1 |
|
ISO |
associated with alcohol dependence DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:15162526 PMID:20364586 PMID:29765251 |
RGD:14700882 RGD:14700899 |
NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102
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G |
LOC101975674 |
cytochrome P450 26B1 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895
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G |
LOC101976500 |
haptoglobin |
|
ISO |
protein:increased expression:saliva protein:decreased expression:liver (human) |
RGD |
PMID:24259486 PMID:31041878 |
RGD:152995276 RGD:27095881 |
NCBI chrNW_004936475:21,841,054...21,845,821
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LOC101976513 |
calmodulin-like protein 3 |
severity |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:29445139 |
RGD:151665319 |
NCBI chrNW_004936484:8,976,512...8,977,792
Ensembl chrNW_004936484:8,977,252...8,977,701
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G |
LOC101977070 |
PTTG1 regulator of sister chromatid separation, securin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936841:274,458...275,148
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G |
LOC120889510 |
insulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
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G |
Loxl3 |
lysyl oxidase like 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35841383 |
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NCBI chrNW_004936556:745,798...765,926
Ensembl chrNW_004936556:745,798...765,918
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Lpar1 |
lysophosphatidic acid receptor 1 |
|
ISO |
|
RGD |
PMID:19000703 |
RGD:2317680 |
NCBI chrNW_004936559:2,187,791...2,331,587
Ensembl chrNW_004936559:2,259,420...2,332,806
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G |
Lrat |
lecithin retinol acyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936576:1,491,480...1,498,568
Ensembl chrNW_004936576:1,492,297...1,501,917
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G |
Lrp1b |
LDL receptor related protein 1B |
exacerbates |
ISO |
protein:increased expression:liver (human) DNA:mutations:multiple: (human) |
RGD |
PMID:33324588 PMID:33391418 |
RGD:150429776 RGD:150429785 |
NCBI chrNW_004936469:35,000,773...36,160,216
Ensembl chrNW_004936469:35,203,594...36,159,283
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G |
Lrrc1 |
leucine rich repeat containing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936476:7,016,435...7,141,398
Ensembl chrNW_004936476:7,015,891...7,141,564
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G |
Lrrc56 |
leucine rich repeat containing 56 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17601930 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20937837 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22420426 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25815234 PMID:25914166 PMID:26467025 PMID:26619011 PMID:26778095 PMID:27195699 PMID:27283355 PMID:27444071 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:30055033 PMID:30138938 PMID:30191474 PMID:31394527 PMID:31560489 PMID:31564432 PMID:31775759 PMID:32371413 PMID:32732226 PMID:33027564 PMID:33372952 PMID:34008892 PMID:34958143 PMID:168335863 More...
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NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
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Lrrc59 |
leucine rich repeat containing 59 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
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NCBI chrNW_004936490:11,296,590...11,308,379
Ensembl chrNW_004936490:11,296,530...11,310,946
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G |
Lyve1 |
lymphatic vessel endothelial hyaluronan receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936528:7,788,560...7,802,821
Ensembl chrNW_004936528:7,788,352...7,802,902
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G |
Lztr1 |
leucine zipper like post translational regulator 1 |
|
ISO |
DNA:missense mutation:cds, liver (human) |
RGD |
PMID:28622513 |
RGD:151893487 |
NCBI chrNW_004936619:2,505,300...2,523,500
Ensembl chrNW_004936619:2,505,542...2,523,500
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G |
Mad2l1 |
mitotic arrest deficient 2 like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936662:92,421...98,531
Ensembl chrNW_004936662:92,328...99,517
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Map2k2 |
mitogen-activated protein kinase kinase 2 |
exacerbates |
ISO |
protein:increased expression:liver, cytosol (rat) mRNA:increased expression:liver (human) |
RGD |
PMID:9397988 PMID:33553243 |
RGD:150530475 RGD:150530477 |
NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
|
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:32850377 |
RGD:150429765 |
NCBI chrNW_004936595:4,762,327...4,828,433
Ensembl chrNW_004936595:4,727,108...4,830,662
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Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
exacerbates |
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:31310010 |
RGD:150573714 |
NCBI chrNW_004936480:11,082,811...11,156,691
Ensembl chrNW_004936480:11,083,605...11,156,691
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Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
ameliorates |
ISO |
|
RGD |
PMID:26560698 |
RGD:11342977 |
NCBI chrNW_004936613:3,791,684...3,813,857
Ensembl chrNW_004936613:3,791,681...3,813,892
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
ameliorates treatment severity |
ISO |
human cell line in a mouse model human recombinant gene and cell line in a mouse model |
RGD |
PMID:21196414 PMID:27010469 PMID:31922225 |
RGD:151347673 RGD:151347674 RGD:151347839 |
NCBI chrNW_004936713:515,388...616,024
Ensembl chrNW_004936713:435,238...612,835
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Mapk1 |
mitogen-activated protein kinase 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:27468214 |
RGD:401976278 |
NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646
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G |
Mapk14 |
mitogen-activated protein kinase 14 |
treatment exacerbates |
ISO |
|
RGD |
PMID:23271722 PMID:25216638 |
RGD:151665347 RGD:151665348 |
NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232
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Mapk8 |
mitogen-activated protein kinase 8 |
ameliorates |
ISO |
protein:decreased phosphorylation:liver (human) |
RGD |
PMID:33875785 |
RGD:150340688 |
NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907
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Mapt |
microtubule associated protein tau |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936541:2,381,411...2,479,984
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Marco |
macrophage receptor with collagenous structure |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936469:51,323,746...51,366,551
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Mat1a |
methionine adenosyltransferase 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12060674 |
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NCBI chrNW_004936716:126,628...142,986
Ensembl chrNW_004936716:126,574...143,155
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Mbtps1 |
membrane bound transcription factor peptidase, site 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 |
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NCBI chrNW_004936641:3,696,506...3,751,558
Ensembl chrNW_004936641:3,696,536...3,751,598
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G |
Mbtps2 |
membrane bound transcription factor peptidase, site 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 |
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NCBI chrNW_004936624:2,464,152...2,510,984
Ensembl chrNW_004936624:2,463,909...2,511,158
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Mcm10 |
minichromosome maintenance 10 replication initiation factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004937104:132,692...160,965
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936798:756,350...768,600
Ensembl chrNW_004936798:756,588...765,338
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Mcm7 |
minichromosome maintenance complex component 7 |
susceptibility |
ISO |
associated with hepatitis B;miRNA:increased expression:liver (human) associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human) |
RGD |
PMID:24416400 PMID:27298561 |
RGD:15042853 RGD:15042885 |
NCBI chrNW_004936543:238,573...246,746
Ensembl chrNW_004936543:233,960...246,746
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Mcm9 |
minichromosome maintenance 9 homologous recombination repair factor |
|
ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936658:1,657,226...1,734,150
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Mdm2 |
MDM2 proto-oncogene |
susceptibility |
ISO |
DNA:transversion:promoter:g.-309T>G (human) |
RGD |
PMID:20019189 |
RGD:2317357 |
NCBI chrNW_004936545:6,709,903...6,732,334
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Me1 |
malic enzyme 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
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NCBI chrNW_004936510:7,425,983...7,571,090
Ensembl chrNW_004936510:7,426,347...7,571,553
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G |
Mecp2 |
methyl-CpG binding protein 2 |
|
ISO |
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:11844796 PMID:26189965 |
RGD:2289670 |
NCBI chrNW_004936809:902,938...967,771
Ensembl chrNW_004936809:911,764...966,839
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Med1 |
mediator complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20007298 |
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NCBI chrNW_004936490:14,625,201...14,663,184
Ensembl chrNW_004936490:14,625,897...14,657,802
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G |
Melk |
maternal embryonic leucine zipper kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936524:4,479,639...4,544,561
Ensembl chrNW_004936524:4,469,256...4,544,290
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
severity |
ISO |
protein:increased expression:liver (human) ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma |
RGD OMIM ClinVar |
PMID:21774103 PMID:21970370 PMID:22703879 PMID:24728327 PMID:25741868 PMID:28259294 PMID:28492532 PMID:29303510 PMID:29641532 More...
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RGD:152995524 |
NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179
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G |
Mfsd2a |
MFSD2 lysolipid transporter A, lysophospholipid |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936474:21,790,807...21,803,336
Ensembl chrNW_004936474:21,790,747...21,803,360
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Mki67 |
marker of proliferation Ki-67 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936486:15,561,327...15,587,109
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G |
Mlxipl |
MLX interacting protein like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
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NCBI chrNW_004936543:2,839,105...2,856,997
Ensembl chrNW_004936543:2,839,105...2,857,002
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G |
Mme |
membrane metalloendopeptidase |
|
ISO |
|
RGD |
PMID:8302012 |
RGD:13801035 |
NCBI chrNW_004936519:2,513,896...2,595,896
Ensembl chrNW_004936519:2,513,704...2,595,971
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G |
Mmp14 |
matrix metallopeptidase 14 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33010264 |
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NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
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G |
Mmp2 |
matrix metallopeptidase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20084675 |
|
NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851
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G |
Mmp9 |
matrix metallopeptidase 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20084675 PMID:21681821 |
RGD:8547864 |
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
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G |
Mogat2 |
monoacylglycerol O-acyltransferase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936498:4,464,453...4,482,237
Ensembl chrNW_004936498:4,464,427...4,481,509
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G |
Mpl |
MPL proto-oncogene, thrombopoietin receptor |
|
ISO |
human cells in mouse model |
RGD |
PMID:23157389 |
RGD:126925755 |
NCBI chrNW_004936474:24,744,673...24,757,189
Ensembl chrNW_004936474:24,744,673...24,757,085
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G |
Mpo |
myeloperoxidase |
susceptibility disease_progression |
ISO |
associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human) associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:19731237 PMID:21907168 |
RGD:26923907 RGD:27095879 |
NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070
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G |
Mro |
maestro |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936497:12,468,839...12,482,645
Ensembl chrNW_004936497:12,468,810...12,484,070
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G |
Msh3 |
mutS homolog 3 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
ClinVar |
PMID:28492532 |
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NCBI chrNW_004936469:82,967...275,772
Ensembl chrNW_004936469:83,285...273,561
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G |
Msh5 |
mutS homolog 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936727:1,776,038...1,794,152
Ensembl chrNW_004936727:1,777,570...1,793,711
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G |
Mtbp |
MDM2 binding protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29765550 |
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NCBI chrNW_004936470:26,312,670...26,386,410
Ensembl chrNW_004936470:26,312,590...26,386,427
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G |
Mtdh |
metadherin |
treatment |
ISO |
human cells in a mouse model |
RGD |
PMID:26351209 |
RGD:11096879 |
NCBI chrNW_004936470:45,016,099...45,079,709
Ensembl chrNW_004936470:45,016,099...45,079,710
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G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:3878730 |
RGD:2302305 |
NCBI chrNW_004936556:462,998...475,092
Ensembl chrNW_004936556:462,974...475,159
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G |
Mthfr |
methylenetetrahydrofolate reductase |
disease_progression onset susceptibility |
ISO |
DNA:SNP: :677C>T(human) DNA:SNP: :1298A>C(human) DNA:SNPs: :677C>T, 1298A>C(human) DNA:SNP,haplotype: :677C>T, 1298A>C(human) |
RGD |
PMID:17503006 PMID:17659576 PMID:19035314 PMID:23996892 |
RGD:14696703 RGD:14696704 RGD:14696707 RGD:14696708 |
NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193
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G |
Mtor |
mechanistic target of rapamycin kinase |
severity |
ISO |
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:liver (human) |
CTD RGD |
PMID:21147110 PMID:25371154 |
RGD:152995471 |
NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342
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G |
Mtrr |
5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
susceptibility |
ISO |
DNA:SNP: :66A>G(human) |
RGD |
PMID:19035314 |
RGD:14696707 |
NCBI chrNW_004936643:379,790...410,034
Ensembl chrNW_004936643:380,968...409,464
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G |
Mvk |
mevalonate kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
|
NCBI chrNW_004936769:1,274,595...1,295,186
Ensembl chrNW_004936769:1,274,540...1,298,178
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G |
Mybl2 |
MYB proto-oncogene like 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936530:2,918,924...2,953,467
Ensembl chrNW_004936530:2,918,951...2,953,467
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
treatment severity |
ISO |
OMIM:114550 mRNA:increased expression:liver (rat) mRNA:increased expression:liver (human) CTD Direct Evidence: marker/mechanism |
RGD MouseDO CTD |
PMID:9029167 PMID:12029619 PMID:15565109 PMID:21644509 PMID:22076107 PMID:22129741 PMID:22434528 PMID:29698666 More...
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RGD:6903288 RGD:7240567 RGD:7240695 RGD:7241004 |
NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965
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G |
Myd88 |
MYD88 innate immune signal transduction adaptor |
exacerbates treatment ameliorates |
ISO |
mRNA:increased expression:liver (human) human gene and cell in a mouse model mouse cell line in a mouse model human cell line in a mouse model protein:increased expression:liver (human) protein, mRNA:decreased expression:liver (human) |
RGD |
PMID:17615358 PMID:24603331 PMID:26985932 PMID:28370778 PMID:29022910 PMID:31068809 PMID:31074165 PMID:32144747 PMID:33575076 More...
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RGD:150520022 RGD:150520169 RGD:150521532 RGD:150521534 RGD:150524327 RGD:150524329 RGD:150524330 RGD:150524334 RGD:150530285 |
NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
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G |
Nbn |
nibrin |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer |
ClinVar |
PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 PMID:10848790 PMID:10852373 PMID:11093281 PMID:11279524 PMID:11953735 PMID:12123493 PMID:12505263 PMID:12833396 PMID:12845677 PMID:14973119 PMID:15185344 PMID:15279809 PMID:16033915 PMID:16544999 PMID:17103455 PMID:18606567 PMID:18940477 PMID:19635536 PMID:19908051 PMID:20444919 PMID:22131123 PMID:22293976 PMID:22373003 PMID:22491912 PMID:22941933 PMID:23317186 PMID:24033266 PMID:24113799 PMID:25485873 PMID:25741868 PMID:25980754 PMID:26083025 PMID:26467025 PMID:26822949 PMID:26845104 PMID:27150568 PMID:27616075 PMID:28492532 PMID:28873162 PMID:29368341 PMID:29419426 PMID:30426508 PMID:31173646 PMID:32295079 PMID:33050356 PMID:33471974 PMID:33471991 PMID:33840814 PMID:34072463 PMID:34072659 PMID:34544220 PMID:35309086 More...
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NCBI chrNW_004936544:3,773,828...3,812,673
Ensembl chrNW_004936544:3,775,220...3,808,837
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G |
Ncapg |
non-SMC condensin I complex subunit G |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936477:10,408,347...10,445,361
Ensembl chrNW_004936477:10,405,997...10,445,206
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G |
Ncaph |
non-SMC condensin I complex subunit H |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936744:440,958...468,964
Ensembl chrNW_004936744:440,956...468,972
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
exacerbates |
ISO |
|
RGD |
PMID:22556267 PMID:28273073 |
RGD:153002573 RGD:153002576 |
NCBI chrNW_004936496:14,844,923...15,102,922
Ensembl chrNW_004936496:14,844,855...15,016,454
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G |
Ndc80 |
NDC80 kinetochore complex component |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936672:1,872,205...1,910,956
Ensembl chrNW_004936672:1,872,193...1,909,675
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G |
Neil3 |
nei like DNA glycosylase 3 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (human) |
CTD RGD |
PMID:28284560 PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936516:7,739,191...7,781,735
Ensembl chrNW_004936516:7,739,157...7,782,024
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G |
Nek2 |
NIMA related kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936557:1,683,027...1,695,410
Ensembl chrNW_004936557:1,682,984...1,695,414
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G |
Nf2 |
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor |
disease_progression |
ISO |
protein:decreased expression:liver DNA, protein:SNP, increased expression:intron, liver |
RGD |
PMID:26443326 PMID:27289045 PMID:29130106 |
RGD:11076529 RGD:150530489 RGD:150530504 |
NCBI chrNW_004936657:3,536,212...3,622,999
Ensembl chrNW_004936657:3,536,141...3,623,821
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G |
Nfe2l1 |
NFE2 like bZIP transcription factor 1 |
|
ISO |
OMIM:114550 |
MouseDO |
|
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NCBI chrNW_004936490:13,265,269...13,279,164
Ensembl chrNW_004936490:13,266,347...13,279,206
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:26619011 PMID:29018201 |
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NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
disease_progression treatment |
ISO |
associated with Chronic Hepatitis B;DNA:insertion/deletion:3'utr: -94ins/delATTG (rs28720239) (human) |
RGD |
PMID:19797428 PMID:25999787 |
RGD:152177911 RGD:40400751 |
NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435
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G |
Nfkbia |
NFKB inhibitor alpha |
susceptibility disease_progression |
ISO |
CTD Direct Evidence: therapeutic associated with hepatitis B;DNA:SNP:promoter:-826C>T (rs2233406) (human) associated with Chronic Hepatitis B;DNA:SNPs,haplotype:3'utr,promoter: 826C>T,881A>G (rs2233406,rs3138053) (human) |
CTD RGD |
PMID:19797428 PMID:22022477 PMID:25223483 |
RGD:40400751 RGD:40902986 |
NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612
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G |
Nkx3-1 |
NK3 homeobox 1 |
treatment |
ISO |
mRNA:decreased expression:liver human gene in a mouse model |
RGD |
PMID:28972178 |
RGD:14401599 |
NCBI chrNW_004936555:7,087,677...7,091,334
Ensembl chrNW_004936555:7,088,577...7,091,334
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G |
Nlrc3 |
NLR family CARD domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30081150 |
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NCBI chrNW_004936694:757,121...773,924
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G |
Nlrc5 |
NLR family CARD domain containing 5 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:27338800 |
RGD:15003194 |
NCBI chrNW_004936475:9,137,929...9,218,682
Ensembl chrNW_004936475:9,168,391...9,217,251
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G |
Nnmt |
nicotinamide N-methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936612:333,421...351,202
Ensembl chrNW_004936612:333,421...351,202
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G |
Nos2 |
nitric oxide synthase 2 |
treatment |
ISO |
|
RGD |
PMID:25999787 |
RGD:152177911 |
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
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G |
Notch3 |
notch receptor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429
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G |
Nr0b2 |
nuclear receptor subfamily 0 group B member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23811326 |
|
NCBI chrNW_004936474:11,316,857...11,319,669
Ensembl chrNW_004936474:11,316,700...11,319,669
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G |
Nr1h2 |
nuclear receptor subfamily 1 group H member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
|
NCBI chrNW_004936889:223,137...229,968
Ensembl chrNW_004936889:223,101...229,990
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G |
Nr1h4 |
nuclear receptor subfamily 1 group H member 4 |
|
ISO |
mRNA:splice variant(s):liver (human) OMIM:114550 intestinally expressed human gene in mouse model CTD Direct Evidence: marker/mechanism |
RGD MouseDO CTD |
PMID:23213087 PMID:23811326 PMID:24954587 PMID:25496033 |
RGD:14696796 RGD:14928330 RGD:14928334 |
NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034
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G |
Nras |
NRAS proto-oncogene, GTPase |
severity disease_progression |
ISO |
mRNA, protein:increased expression:liver (mouse, human) ClinVar Annotator: match by term: Hepatocellular cancer human gene in mouse model |
RGD ClinVar |
PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 PMID:8120410 PMID:10821536 PMID:12460918 PMID:12727991 PMID:14508525 PMID:15899789 PMID:16273091 PMID:16291983 PMID:16434492 PMID:17699718 PMID:18390968 PMID:18633438 PMID:18668139 PMID:18948947 PMID:19075190 PMID:19657110 PMID:19880792 PMID:19966803 PMID:20130576 PMID:20149136 PMID:20179705 PMID:20406486 PMID:20619739 PMID:20736745 PMID:21107323 PMID:21305640 PMID:21576590 PMID:21729679 PMID:21829508 PMID:21993994 PMID:22407852 PMID:22499344 PMID:22718121 PMID:22761467 PMID:22773810 PMID:23076151 PMID:23392294 PMID:23400451 PMID:23414587 PMID:23515407 PMID:23538902 PMID:23569304 PMID:23614898 PMID:24006476 PMID:24033266 PMID:24148783 PMID:24370118 PMID:24671188 PMID:25157968 PMID:25348872 PMID:25695684 PMID:25741868 PMID:26619011 PMID:26821351 PMID:27050078 PMID:28492532 PMID:28780248 PMID:30685691 More...
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RGD:14696775 RGD:14696793 |
NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590
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G |
Nrg1 |
neuregulin 1 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) associated with hepatitis C;mRNA:altered expression:liver (human |
RGD |
PMID:17393520 PMID:27514687 |
RGD:39456104 RGD:39456110 |
NCBI chrNW_004936766:1,104,841...1,306,368
Ensembl chrNW_004936766:1,104,728...1,305,972
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G |
Nrp1 |
neuropilin 1 |
disease_progression |
ISO |
protein:decreased expression:liver |
RGD |
PMID:25333267 |
RGD:126848812 |
NCBI chrNW_004936574:1,694,433...1,834,720
Ensembl chrNW_004936574:1,694,336...1,834,720
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
treatment disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:28284560 PMID:30653265 PMID:31933938 |
RGD:28867240 RGD:28912742 |
NCBI chrNW_004936481:21,342,667...21,371,311
Ensembl chrNW_004936481:21,342,786...21,371,328
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G |
Nusap1 |
nucleolar and spindle associated protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936471:4,705,757...4,732,446
Ensembl chrNW_004936471:4,705,866...4,731,903
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G |
Oit3 |
oncoprotein induced transcript 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936521:6,098,071...6,123,740
Ensembl chrNW_004936521:6,098,111...6,123,745
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G |
Olfml2a |
olfactomedin like 2A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936487:12,999,818...13,031,539
Ensembl chrNW_004936487:12,999,901...13,027,760
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G |
Olfml2b |
olfactomedin like 2B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936831:169,866...210,974
Ensembl chrNW_004936831:169,864...211,315
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G |
Orc1 |
origin recognition complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936522:8,580,661...8,610,750
Ensembl chrNW_004936522:8,586,591...8,610,747
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G |
Otc |
ornithine transcarbamylase |
severity |
ISO |
mRNA:altered expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936502:5,234,253...5,291,891
Ensembl chrNW_004936502:5,234,253...5,291,891
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G |
Pafah1b1 |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
disease_progression |
ISO |
mRNA,protein:decreased expression:liver: |
RGD |
PMID:21569763 |
RGD:12790589 |
NCBI chrNW_004936538:8,612,142...8,693,698
Ensembl chrNW_004936538:8,612,049...8,694,015
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G |
Pamr1 |
peptidase domain containing associated with muscle regeneration 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936533:2,684,826...2,764,682
Ensembl chrNW_004936533:2,684,479...2,764,874
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G |
Park7 |
Parkinsonism associated deglycase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817
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G |
Parp1 |
poly(ADP-ribose) polymerase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18695907 |
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NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
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G |
Pbk |
PDZ binding kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936675:704,001...722,769
Ensembl chrNW_004936675:704,516...722,755
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 PMID:28284560 |
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NCBI chrNW_004936530:361,872...367,005
Ensembl chrNW_004936530:361,872...367,005
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G |
Pclaf |
PCNA clamp associated factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936471:24,797,291...24,812,196
Ensembl chrNW_004936471:24,797,393...24,808,227
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Pcna |
proliferating cell nuclear antigen |
treatment |
ISO |
protein:increased expression:liver: |
RGD |
PMID:23219601 PMID:25999787 |
RGD:10448993 RGD:152177911 |
NCBI chrNW_004936485:13,766,221...13,771,215
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G |
Pdcd1 |
programmed cell death 1 |
disease_progression |
ISO |
associated with hepatitis B;DNA:SNP: : +8669 A>G (human) |
RGD |
PMID:21912640 PMID:27034168 |
RGD:40818257 RGD:41410800 |
NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587
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Pdgfb |
platelet derived growth factor subunit B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20506153 |
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NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573
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Pdgfrl |
platelet derived growth factor receptor like |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
OMIM ClinVar |
PMID:7898930 |
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NCBI chrNW_004936614:195,058...241,748
Ensembl chrNW_004936614:195,030...240,502
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G |
Pdia3 |
protein disulfide isomerase family A member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936471:6,809,181...6,834,189
Ensembl chrNW_004936471:6,809,195...6,836,169
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28003426 |
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NCBI chrNW_004936585:4,701,012...4,713,421
Ensembl chrNW_004936585:4,700,418...4,714,450
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G |
Pfas |
phosphoribosylformylglycinamidine synthase |
|
ISO |
protein:increased activity:hepatoma (rat) protein:increased expression:liver |
RGD |
PMID:6722784 |
RGD:5135276 |
NCBI chrNW_004936595:1,483,688...1,499,716
Ensembl chrNW_004936595:1,483,689...1,501,364
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G |
Pfn2 |
profilin 2 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
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G |
Pgd |
phosphogluconate dehydrogenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
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NCBI chrNW_004936623:4,234,869...4,251,690
Ensembl chrNW_004936623:4,234,837...4,252,467
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G |
Pgk1 |
phosphoglycerate kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936547:286,267...310,062
Ensembl chrNW_004936547:286,267...310,062
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G |
Phb1 |
prohibitin 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936490:12,127,065...12,138,870
Ensembl chrNW_004936490:12,127,065...12,138,870
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G |
Phf6 |
PHD finger protein 6 |
exacerbates |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:30888215 PMID:31329335 |
RGD:155260288 RGD:155260308 |
NCBI chrNW_004936691:716,723...767,960
Ensembl chrNW_004936691:716,697...768,016
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G |
Phlda1 |
pleckstrin homology like domain family A member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936568:4,400,094...4,407,900
Ensembl chrNW_004936568:4,404,818...4,406,006
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
treatment severity no_association susceptibility |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma DNA:mutations:exons: DNA:mutation:exon: DNA:SNPs: :rs17849071,rs17849079(human) |
OMIM ClinVar RGD |
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 PMID:15805248 PMID:15930273 PMID:16331247 PMID:16906227 PMID:16930767 PMID:17376864 PMID:17673550 PMID:18676830 PMID:18725974 PMID:19029981 PMID:19223544 PMID:19366826 PMID:19513541 PMID:19903786 PMID:20453058 PMID:20593314 PMID:20619739 PMID:21078999 PMID:21430269 PMID:21558396 PMID:21824802 PMID:22162582 PMID:22162589 PMID:22209294 PMID:22271473 PMID:22357840 PMID:22370636 PMID:22658544 PMID:22729222 PMID:22729223 PMID:22729224 PMID:23066039 PMID:23100325 PMID:23408298 PMID:23888070 PMID:23946963 PMID:24033266 PMID:24265155 PMID:24559322 PMID:24673525 PMID:24782230 PMID:25157968 PMID:25599672 PMID:25741868 PMID:25880439 PMID:25999787 PMID:26266975 PMID:26266985 PMID:26619011 PMID:26627007 PMID:26637981 PMID:26822237 PMID:26823876 PMID:26851524 PMID:27126994 PMID:27626068 PMID:27631024 PMID:28151489 PMID:28425981 PMID:28492532 PMID:29446767 PMID:29661094 PMID:29758562 PMID:29988677 PMID:30063105 PMID:30376034 PMID:30543347 PMID:31536475 PMID:31775759 PMID:32778138 PMID:34008892 PMID:34496175 PMID:37712948 More...
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RGD:11556371 RGD:14402404 RGD:14402405 RGD:152177911 |
NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
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G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
treatment |
ISO |
|
RGD |
PMID:25999787 |
RGD:152177911 |
NCBI chrNW_004936540:907,118...1,041,814
Ensembl chrNW_004936540:907,112...1,041,848
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
treatment |
ISO |
|
RGD |
PMID:25999787 PMID:31801250 |
RGD:151893509 RGD:152177911 |
NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537
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G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
treatment |
ISO |
|
RGD |
PMID:25999787 |
RGD:152177911 |
NCBI chrNW_004936596:3,010,526...3,021,848
Ensembl chrNW_004936596:3,010,488...3,021,920
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
treatment |
ISO |
|
RGD |
PMID:25999787 |
RGD:152177911 |
NCBI chrNW_004936474:27,095,125...27,171,416
Ensembl chrNW_004936474:27,095,100...27,171,252
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G |
Pinx1 |
PIN2 (TERF1) interacting telomerase inhibitor 1 |
disease_progression |
ISO |
associated with Chronic Hepatitis B; DNA:SNP::rs1469557(human) |
RGD |
PMID:27221889 |
RGD:152977752 |
NCBI chrNW_004936675:2,641,851...2,706,201
Ensembl chrNW_004936675:2,640,068...2,706,238
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G |
Pitpnm3 |
PITPNM family member 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936677:1,451,974...1,528,864
Ensembl chrNW_004936677:1,430,391...1,529,484
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G |
Pitx1 |
paired like homeodomain 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936597:2,211,087...2,217,065
Ensembl chrNW_004936597:2,211,080...2,217,071
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G |
Pkm |
pyruvate kinase M1/2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
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NCBI chrNW_004936471:31,589,322...31,617,891
Ensembl chrNW_004936471:31,589,324...31,617,873
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G |
Pkmyt1 |
protein kinase, membrane associated tyrosine/threonine 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936694:1,191,534...1,196,532
Ensembl chrNW_004936694:1,188,442...1,199,079
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G |
Pkp1 |
plakophilin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936567:3,089,902...3,138,252
Ensembl chrNW_004936567:3,089,881...3,138,331
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G |
Plac8 |
placenta associated 8 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936738:1,484,905...1,503,181
Ensembl chrNW_004936738:1,484,859...1,503,302
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G |
Plau |
plasminogen activator, urokinase |
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ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877
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G |
Plcg1 |
phospholipase C gamma 1 |
ameliorates |
ISO |
human cell line in a mouse model |
RGD |
PMID:30623526 |
RGD:151356937 |
NCBI chrNW_004936561:598,372...631,575
Ensembl chrNW_004936561:598,382...631,581
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G |
Plk1 |
polo like kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936501:8,321,415...8,332,414
Ensembl chrNW_004936501:8,321,305...8,332,424
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G |
Plk4 |
polo like kinase 4 |
sexual_dimorphism |
ISO |
DNA:hypermethylation:promoter |
RGD |
PMID:21324136 |
RGD:27226690 |
NCBI chrNW_004936642:2,837,041...2,855,369
Ensembl chrNW_004936642:2,837,022...2,855,103
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G |
Plod3 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 |
treatment |
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:29059470 |
RGD:155791679 |
NCBI chrNW_004936543:1,090,268...1,097,170
Ensembl chrNW_004936543:1,090,253...1,097,301
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G |
Plvap |
plasmalemma vesicle associated protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936596:3,511,235...3,523,164
Ensembl chrNW_004936596:3,511,185...3,523,252
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G |
Plxdc1 |
plexin domain containing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936490:14,370,767...14,425,608
Ensembl chrNW_004936490:14,370,795...14,424,209
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G |
Pml |
PML nuclear body scaffold |
exacerbates ameliorates disease_progression |
ISO |
associated with hepatitis C mRNA:increased expression:liver (mouse) protein:increased expression:liver (human) |
RGD |
PMID:11511788 PMID:26118777 PMID:31144474 |
RGD:41404685 RGD:41404687 RGD:41404690 |
NCBI chrNW_004936471:33,135,186...33,173,218
Ensembl chrNW_004936471:33,135,164...33,177,666
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Pms2 |
PMS1 homolog 2, mismatch repair system component |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
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NCBI chrNW_004936750:439,396...468,747
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G |
Pnpla3 |
patatin like phospholipase domain containing 3 |
|
ISO |
associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human) |
RGD |
PMID:21319195 |
RGD:14981585 |
NCBI chrNW_004936718:1,620,034...1,638,315
Ensembl chrNW_004936718:1,619,948...1,638,317
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G |
Pnpt1 |
polyribonucleotide nucleotidyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936491:1,989,429...2,032,430
Ensembl chrNW_004936491:1,987,097...2,032,430
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G |
Polg |
DNA polymerase gamma, catalytic subunit |
susceptibility |
ISO |
DNA:SNPs:introns: (rs1061316, rs758130) (human) |
RGD |
PMID:28457473 |
RGD:15039387 |
NCBI chrNW_004936483:15,178,947...15,196,277
Ensembl chrNW_004936483:15,179,342...15,195,258
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G |
Pon1 |
paraoxonase 1 |
disease_progression |
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936585:4,954,871...4,979,560
Ensembl chrNW_004936585:4,954,869...4,979,591
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Pot1 |
protection of telomeres 1 |
disease_progression |
ISO |
associated with hepatitis B;DNA:SNP: :rs7784168(human) |
RGD |
PMID:23907815 |
RGD:152975963 |
NCBI chrNW_004936605:836,824...919,099
Ensembl chrNW_004936605:836,769...920,201
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Ppara |
peroxisome proliferator activated receptor alpha |
susceptibility |
ISO |
associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) |
RGD |
PMID:19119483 |
RGD:15042881 |
NCBI chrNW_004936629:3,672,445...3,725,645
Ensembl chrNW_004936629:3,672,460...3,725,626
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
severity |
ISO |
CTD Direct Evidence: therapeutic protein:decreased expression:liver |
CTD RGD |
PMID:16374840 PMID:27451128 |
RGD:14694822 |
NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743
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G |
Ppat |
phosphoribosyl pyrophosphate amidotransferase |
|
ISO |
protein:increased activity:hepatoma (rat) |
RGD |
PMID:6327016 |
RGD:5135035 |
NCBI chrNW_004936482:18,606,124...18,648,989
Ensembl chrNW_004936482:18,606,124...18,648,681
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G |
Ppp1r1a |
protein phosphatase 1 regulatory inhibitor subunit 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15010824 |
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NCBI chrNW_004936512:11,765,769...11,775,573
Ensembl chrNW_004936512:11,767,172...11,775,573
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G |
Ppp1r9a |
protein phosphatase 1 regulatory subunit 9A |
onset |
ISO |
protein:increased expression:liver (rat) |
RGD |
PMID:20935162 |
RGD:10002734 |
NCBI chrNW_004936585:4,981,555...5,277,185
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G |
Ppp1r9b |
protein phosphatase 1 regulatory subunit 9B |
severity |
ISO |
mRNA, protein:decreased expression:liver (human) |
RGD |
PMID:23591196 |
RGD:10043803 |
NCBI chrNW_004936490:11,497,389...11,514,191
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G |
Prc1 |
protein regulator of cytokinesis 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936483:16,034,577...16,061,856
Ensembl chrNW_004936483:16,034,550...16,060,909
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G |
Prdm1 |
PR/SET domain 1 |
disease_progression |
ISO |
associated with hepatitis B; associated with hepatitis B;DNA:SNP: :rs1010273(human) |
RGD |
PMID:31100710 PMID:31376415 |
RGD:150530465 RGD:150530466 |
NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683
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G |
Prdx1 |
peroxiredoxin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27517622 |
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NCBI chrNW_004936474:26,641,776...26,653,291
Ensembl chrNW_004936474:26,639,259...26,653,328
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G |
Prdx2 |
peroxiredoxin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936659:1,894,423...1,897,690
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G |
Prdx6 |
peroxiredoxin 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936481:14,223,422...14,233,634
Ensembl chrNW_004936481:14,222,696...14,233,641
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G |
Prex2 |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 |
exacerbates |
ISO |
mRNA:increased expression:liver (human) mRNA:decreased expression:liver (human) protein:increased expression:liver (human) |
RGD |
PMID:25151370 PMID:28000796 PMID:28205209 PMID:31776854 |
RGD:151665185 RGD:151665186 RGD:151665188 RGD:151665343 |
NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346
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Prkn |
parkin RBR E3 ubiquitin protein ligase |
severity |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:28862485 |
RGD:13432206 |
NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872
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Prl |
prolactin |
onset |
ISO |
protein:increased expression:serum (human) |
RGD |
PMID:22392353 |
RGD:125097525 |
NCBI chrNW_004936552:7,204,298...7,212,632
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Prom1 |
prominin 1 |
|
ISO |
mRNA:increased expression:liver (mouse) |
RGD |
PMID:26569409 |
RGD:11344640 |
NCBI chrNW_004936477:11,878,261...12,017,228
Ensembl chrNW_004936477:11,878,012...12,018,177
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G |
Ptch1 |
patched 1 |
severity disease_progression |
ISO |
|
RGD |
PMID:18538319 PMID:22911366 |
RGD:150523837 RGD:150523842 |
NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476
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Pten |
phosphatase and tensin homolog |
severity treatment exacerbates |
ISO |
CTD Direct Evidence: marker/mechanism OMIM:114550 protein:decreased expression:liver (human) associated with hepatitis B;protein:decreased expression:liver (human) associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human) |
CTD MouseDO RGD |
PMID:12115563 PMID:12673720 PMID:27022031 PMID:29303510 PMID:30690477 PMID:31801250 More...
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RGD:127285591 RGD:127285603 RGD:127285610 RGD:151893509 RGD:152995524 |
NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
treatment severity susceptibility |
ISO |
protein:increased expression:liver, cytosol DNA:SNP:promoter:-1195A>G (rs689466) (human) mRNA,protein:decreased expression:liver CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:11872629 PMID:12024111 PMID:14563831 PMID:15800977 PMID:16374840 PMID:17510421 PMID:18373278 PMID:24720952 PMID:24759835 PMID:25999787 More...
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RGD:14695010 RGD:14695011 RGD:14695012 RGD:152177911 RGD:2300283 |
NCBI chrNW_004936481:3,821,564...3,828,086
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G |
Pth1r |
parathyroid hormone 1 receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936596:674,088...693,191
Ensembl chrNW_004936596:674,088...693,213
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G |
Ptk2 |
protein tyrosine kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:14578863 PMID:17203219 |
RGD:2292584 |
NCBI chrNW_004936470:10,379,855...10,578,531
Ensembl chrNW_004936470:10,379,872...10,578,543
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G |
Ptpn13 |
protein tyrosine phosphatase non-receptor type 13 |
disease_progression susceptibility |
ISO |
DNA:SNP: :p.Y2081D(human) |
RGD |
PMID:16489062 PMID:26801674 |
RGD:152176666 RGD:152599190 |
NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001
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G |
Ptprb |
protein tyrosine phosphatase receptor type B |
disease_progression |
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:30237408 |
RGD:151361293 |
NCBI chrNW_004936545:8,150,766...8,235,674
Ensembl chrNW_004936545:8,147,291...8,235,715
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Pycard |
PYD and CARD domain containing |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17471463 |
|
NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805
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G |
Pygl |
glycogen phosphorylase L |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:2885971 |
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NCBI chrNW_004936495:14,692,688...14,728,663
Ensembl chrNW_004936495:14,692,332...14,730,231
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Rac1 |
Rac family small GTPase 1 |
exacerbates |
ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human) mRNA:increased expression:liver (human) |
CTD RGD |
PMID:18506888 PMID:20522449 PMID:33482578 |
RGD:153298967 RGD:153350129 |
NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676
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Racgap1 |
Rac GTPase activating protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936512:7,665,144...7,696,615
Ensembl chrNW_004936512:7,665,208...7,689,112
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Rad21 |
RAD21 cohesin complex component |
treatment exacerbates susceptibility |
ISO |
human cells in a mouse model protein:increased expression:liver (human) mRNA:increased expression:liver (human) associated with hepatitis c, liver cirrhosis;mRNA:increased expression:liver (human) |
RGD |
PMID:28434945 PMID:30698808 PMID:32596342 PMID:33251678 |
RGD:150520026 RGD:150520029 RGD:150520030 RGD:150520035 |
NCBI chrNW_004936470:29,377,793...29,403,422
Ensembl chrNW_004936470:29,377,734...29,407,312
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Rad50 |
RAD50 double strand break repair protein |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:16385572 PMID:18281469 PMID:19409520 PMID:24894818 PMID:25452441 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29961768 PMID:31159747 PMID:31589614 PMID:32295079 More...
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NCBI chrNW_004936647:2,546,100...2,637,524
Ensembl chrNW_004936647:2,543,599...2,637,846
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Rad52 |
RAD52 homolog, DNA repair protein |
onset susceptibility |
ISO |
mRNA,protein:increased expression:liver (human) associated with hepatitis B;DNA:SNP:3'utr: (rs7963551) (human) |
RGD |
PMID:24729511 PMID:31719794 |
RGD:151361199 RGD:151361207 |
NCBI chrNW_004936606:1,070,336...1,099,684
Ensembl chrNW_004936606:1,066,905...1,099,703
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Rad54l |
RAD54 like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936474:27,276,570...27,316,427
Ensembl chrNW_004936474:27,280,573...27,316,428
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Rara |
retinoic acid receptor alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18026104 |
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NCBI chrNW_004936490:15,376,217...15,420,638
Ensembl chrNW_004936490:15,376,205...15,421,611
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Rb1 |
RB transcriptional corepressor 1 |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:12029619 PMID:14961299 PMID:33841550 |
RGD:152998960 |
NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846
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Rbm10 |
RNA binding motif protein 10 |
disease_progression |
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:32572914 |
RGD:151356975 |
NCBI chrNW_004936502:12,923,890...12,952,179
Ensembl chrNW_004936502:12,925,910...12,955,470
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Rcan1 |
regulator of calcineurin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936500:7,942,099...7,950,256
Ensembl chrNW_004936500:7,942,133...7,950,271
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Recql |
RecQ like helicase |
disease_progression |
ISO |
protein:increased expression:liver |
RGD |
PMID:18422747 |
RGD:2317370 |
NCBI chrNW_004936548:5,349,878...5,384,603
Ensembl chrNW_004936548:5,362,517...5,384,338
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Ret |
ret proto-oncogene |
severity |
ISO |
protein:increased expression:liver (human) ClinVar Annotator: match by term: Hepatocellular carcinoma |
RGD ClinVar |
PMID:7784092 PMID:7845675 PMID:7911697 PMID:9111992 PMID:9242375 PMID:9263528 PMID:11230481 PMID:12116277 PMID:14715928 PMID:15184865 PMID:15855933 PMID:16736292 PMID:17047083 PMID:17097365 PMID:18062802 PMID:25157968 PMID:25810047 PMID:26046350 PMID:28350084 PMID:28492532 PMID:29656518 More...
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RGD:150340602 |
NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602
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Rgn |
regucalcin |
|
ISO |
protein:decreased expression:liver |
RGD |
PMID:21683810 |
RGD:5509919 |
NCBI chrNW_004936502:12,872,938...12,891,270
Ensembl chrNW_004936502:12,872,824...12,891,506
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Rictor |
RPTOR independent companion of MTOR complex 2 |
severity |
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:25371154 PMID:29303510 |
RGD:152995471 RGD:152995524 |
NCBI chrNW_004936518:3,198,312...3,314,393
Ensembl chrNW_004936518:3,198,337...3,310,000
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Rit1 |
Ras like without CAAX 1 |
ameliorates |
ISO |
human cells in mouse model |
RGD |
PMID:31247273 |
RGD:152999016 |
NCBI chrNW_004936580:5,157,351...5,166,790
Ensembl chrNW_004936580:5,156,565...5,167,040
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Rnd3 |
Rho family GTPase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936469:26,981,358...26,998,902
Ensembl chrNW_004936469:26,981,318...27,000,739
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Rnf157 |
ring finger protein 157 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936594:1,290,515...1,359,262
Ensembl chrNW_004936594:1,290,413...1,359,263
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Rnf43 |
ring finger protein 43 |
exacerbates |
ISO |
human cells in a mouse model |
RGD |
PMID:23136185 |
RGD:151361219 |
NCBI chrNW_004936490:4,660,904...4,742,669
Ensembl chrNW_004936490:4,683,725...4,741,828
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Rnf6 |
ring finger protein 6 |
disease_progression |
ISO |
|
RGD |
PMID:30496760 |
RGD:151665757 |
NCBI chrNW_004936948:57,806...67,875
Ensembl chrNW_004936948:55,699...67,972
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Robo1 |
roundabout guidance receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936505:4,329,428...4,711,310
Ensembl chrNW_004936505:4,330,303...4,709,655
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Rps6 |
ribosomal protein S6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
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NCBI chrNW_004936652:1,252,986...1,255,987
Ensembl chrNW_004936652:1,253,025...1,255,906
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Rps6ka3 |
ribosomal protein S6 kinase A3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22561517 |
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NCBI chrNW_004936624:3,897,878...4,005,664
Ensembl chrNW_004936624:3,897,791...4,000,558
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Rrm1 |
ribonucleotide reductase catalytic subunit M1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18230555 |
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NCBI chrNW_004936498:815,401...848,749
Ensembl chrNW_004936498:815,399...848,793
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Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18230555 PMID:28284560 |
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NCBI chrNW_004936532:6,348,041...6,390,144
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Rspo3 |
R-spondin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936639:2,475,710...2,552,725
Ensembl chrNW_004936639:2,475,710...2,552,725
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Rtkn |
rhotekin |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:27922690 |
RGD:19165144 |
NCBI chrNW_004936556:650,303...665,324
Ensembl chrNW_004936556:650,303...665,324
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Rtp3 |
receptor transporter protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17693185 |
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NCBI chrNW_004936596:392,885...408,892
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Runx3 |
RUNX family transcription factor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:liver |
CTD RGD |
PMID:17094378 PMID:28458013 |
RGD:126775147 |
NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910
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Rxra |
retinoid X receptor alpha |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:26619011 |
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NCBI chrNW_004936669:2,735,111...2,763,060
Ensembl chrNW_004936669:2,738,448...2,763,070
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Ryr3 |
ryanodine receptor 3 |
disease_progression |
ISO |
DNA:SNP:3'UTR:rs1044129(human) |
RGD |
PMID:26309413 |
RGD:155882454 |
NCBI chrNW_004936673:2,078,095...2,434,872
Ensembl chrNW_004936673:1,932,755...2,434,066
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S100a9 |
S100 calcium binding protein A9 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936580:3,228,097...3,230,652
Ensembl chrNW_004936580:3,228,092...3,230,676
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Sardh |
sarcosine dehydrogenase |
severity |
ISO |
mRNA:altered expression:liver tumor (human) |
RGD |
PMID:30901224 |
RGD:152995286 |
NCBI chrNW_004936669:3,244,302...3,297,906
Ensembl chrNW_004936669:3,243,762...3,297,905
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Sav1 |
salvador family WW domain containing protein 1 |
|
ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936495:14,955,234...14,977,720
Ensembl chrNW_004936495:14,954,542...14,976,580
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Scap |
SREBF chaperone |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 |
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NCBI chrNW_004936596:1,124,573...1,180,219
Ensembl chrNW_004936596:1,122,042...1,180,297
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Serpinb5 |
serpin family B member 5 |
disease_progression |
ISO |
associated with hepatitis B; |
RGD |
PMID:26296971 |
RGD:11520929 |
NCBI chrNW_004936497:2,067,796...2,089,965
Ensembl chrNW_004936497:2,069,035...2,089,745
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Serpinf1 |
serpin family F member 1 |
|
ISO |
associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human) |
RGD |
PMID:27748324 |
RGD:27226704 |
NCBI chrNW_004936538:7,885,816...7,898,308
Ensembl chrNW_004936538:7,885,475...7,899,113
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Set |
SET nuclear proto-oncogene |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:26822237 |
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NCBI chrNW_004936487:16,181,764...16,184,706
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Sf3b1 |
splicing factor 3b subunit 1 |
treatment disease_progression |
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma mRNA, protein:increased expression:liver |
RGD ClinVar |
PMID:23634996 PMID:26619011 PMID:33038489 |
RGD:126790494 |
NCBI chrNW_004936506:1,749,591...1,790,860
Ensembl chrNW_004936506:1,749,563...1,791,739
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Sf3b2 |
splicing factor 3b subunit 2 |
|
ISO |
ClinVar Annotator: match by term: Hepatocellular carcinoma |
ClinVar |
PMID:26619011 |
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NCBI chrNW_004936599:3,477,882...3,494,366
Ensembl chrNW_004936599:3,477,589...3,494,354
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Sf3b4 |
splicing factor 3b subunit 4 |
treatment severity |
ISO |
mRNA, protein:increased expression:liver(human) human cells in mouse model mRNA, protein:increased expression:liver (human) mRNA, protein:increased expression:liver (rat) |
RGD |
PMID:29059470 PMID:30391496 |
RGD:155791679 RGD:155804298 |
NCBI chrNW_004936580:260,013...265,057
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Sfn |
stratifin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433
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Sfrp1 |
secreted frizzled related protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936785:1,276,478...1,320,397
Ensembl chrNW_004936785:1,276,420...1,321,017
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Sh3gl1 |
SH3 domain containing GRB2 like 1, endophilin A2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33838155 |
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NCBI chrNW_004936588:2,504,372...2,535,993
Ensembl chrNW_004936588:2,504,374...2,536,011
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Shc1 |
SHC adaptor protein 1 |
|
ISO |
protein:increased expression, increased phosphorylation:hepatocyte |
RGD |
PMID:15375560 |
RGD:1643188 |
NCBI chrNW_004936580:4,511,560...4,522,003
Ensembl chrNW_004936580:4,512,680...4,519,715
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Shh |
sonic hedgehog signaling molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26189965 |
|
NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599
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Sik2 |
salt inducible kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34491613 |
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NCBI chrNW_004936612:2,691,729...2,810,975
Ensembl chrNW_004936612:2,691,524...2,810,981
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Six1 |
SIX homeobox 1 |
severity |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:17008870 |
RGD:11561961 |
NCBI chrNW_004936495:4,839,496...4,842,906
Ensembl chrNW_004936495:4,838,051...4,842,994
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Ska1 |
spindle and kinetochore associated complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936497:12,777,454...12,793,992
Ensembl chrNW_004936497:12,777,334...12,794,032
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Ska3 |
spindle and kinetochore associated complex subunit 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936720:586,730...610,397
Ensembl chrNW_004936720:586,850...605,406
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Skp2 |
S-phase kinase associated protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism protein:increased expression:liver |
CTD RGD |
PMID:12717389 PMID:19533683 |
RGD:2315050 |
NCBI chrNW_004936518:5,635,856...5,664,057
Ensembl chrNW_004936518:5,637,331...5,664,778
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Slc22a1 |
solute carrier family 22 member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745
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Slc25a47 |
solute carrier family 25 member 47 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936604:3,976,677...3,981,572
Ensembl chrNW_004936604:3,978,061...3,980,958
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Slc26a6 |
solute carrier family 26 member 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936529:425,839...435,590
Ensembl chrNW_004936529:424,720...435,293
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Slc2a1 |
solute carrier family 2 member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8364915 |
|
NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713
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Slc2a2 |
solute carrier family 2 member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8364915 |
|
NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947
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Slc38a1 |
solute carrier family 38 member 1 |
disease_progression ameliorates |
ISO |
|
RGD |
PMID:26389641 |
RGD:151361140 |
NCBI chrNW_004936512:4,438,827...4,504,416
Ensembl chrNW_004936512:4,444,684...4,487,165
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Slc5a5 |
solute carrier family 5 member 5 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:15347726 PMID:15520214 |
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NCBI chrNW_004936596:3,176,009...3,188,637
Ensembl chrNW_004936596:3,177,422...3,188,637
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Slc7a5 |
solute carrier family 7 member 5 |
ameliorates disease_progression |
ISO |
mRNA:increased expression:liver |
RGD |
PMID:7532544 PMID:23696029 PMID:26389641 |
RGD:151361140 RGD:151361280 RGD:634202 |
NCBI chrNW_004936641:1,513,110...1,538,955
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Slco1b3 |
solute carrier organic anion transporter family member 1B3 |
exacerbates disease_progression |
ISO |
mRNA,protein:decreased expression:liver (human) |
RGD |
PMID:21626360 PMID:32534581 |
RGD:152995417 RGD:152995423 |
NCBI chrNW_004936548:5,593,908...5,682,187
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Slit2 |
slit guidance ligand 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19100240 |
|
NCBI chrNW_004936477:8,111,212...8,448,567
Ensembl chrNW_004936477:8,109,228...8,446,653
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Smad2 |
SMAD family member 2 |
|
ISO |
|
RGD |
PMID:18971187 |
RGD:12880056 |
NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697
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Smad4 |
SMAD family member 4 |
disease_progression |
ISO |
protein:increased expression:liver: protein:decreased expression:liver |
RGD |
PMID:18971187 PMID:22799322 PMID:23922662 PMID:29924446 |
RGD:12880056 RGD:18182921 RGD:21066341 RGD:21066342 |
NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123
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Smad7 |
SMAD family member 7 |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:25602745 |
RGD:14401589 |
NCBI chrNW_004936497:13,894,586...13,921,978
Ensembl chrNW_004936497:13,894,580...13,922,065
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Smarca4 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
|
ISO |
DNA:SNPs: :rs11879293, rs2072382 (human) |
RGD |
PMID:24556940 |
RGD:127285650 |
NCBI chrNW_004936659:1,152,846...1,246,718
Ensembl chrNW_004936659:1,169,792...1,249,213
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G |
Smarcb1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
disease_progression |
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:27111394 |
RGD:127285647 |
NCBI chrNW_004936619:1,276,239...1,308,945
Ensembl chrNW_004936619:1,275,362...1,308,913
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G |
Smarcc1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 |
ameliorates |
ISO |
mRNA, protein:increased expression:liver (human) |
RGD |
PMID:32514535 |
RGD:151347860 |
NCBI chrNW_004936596:1,257,723...1,407,358
Ensembl chrNW_004936596:1,255,054...1,408,038
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Smc3 |
structural maintenance of chromosomes 3 |
exacerbates |
ISO |
mRNA:increased editing:cds:p.K96R,p.Q103R(human) |
RGD |
PMID:29996118 |
RGD:156430111 |
NCBI chrNW_004936486:1,409,757...1,436,206
Ensembl chrNW_004936486:1,408,045...1,435,875
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G |
Smg9 |
SMG9 nonsense mediated mRNA decay factor |
severity |
ISO |
|
RGD |
PMID:34456727 |
RGD:155882446 |
NCBI chrNW_004936706:908,471...929,075
Ensembl chrNW_004936706:908,867...929,305
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G |
Smo |
smoothened, frizzled class receptor |
disease_progression |
ISO |
DNA:SNP: :rs3824 (human) |
RGD |
PMID:25944162 |
RGD:150340548 |
NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281
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G |
Snai1 |
snail family transcriptional repressor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35841383 |
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NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987
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G |
Snrpe |
small nuclear ribonucleoprotein polypeptide E |
|
ISO |
human gene in a mouse model |
RGD |
PMID:21688285 |
RGD:10768833 |
NCBI chrNW_004936567:849,300...855,214
Ensembl chrNW_004936567:849,397...855,187
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G |
Snw1 |
SNW domain containing 1 |
severity |
ISO |
protein:increased expression:liver (human) |
RGD |
PMID:23696020 |
RGD:11035253 |
NCBI chrNW_004936488:6,494,556...6,531,297
Ensembl chrNW_004936488:6,494,562...6,531,600
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G |
Snx27 |
sorting nexin 27 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:36029209 |
|
NCBI chrNW_004936580:1,815,582...1,893,076
Ensembl chrNW_004936580:1,815,651...1,893,753
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G |
Soat1 |
sterol O-acyltransferase 1 |
exacerbates |
ISO |
associated with hepatitis B;protein:increased expression:liver (human) |
RGD |
PMID:30814741 |
RGD:126925204 |
NCBI chrNW_004936481:9,614,605...9,669,705
Ensembl chrNW_004936481:9,616,850...9,669,705
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G |
Soat2 |
sterol O-acyltransferase 2 |
|
ISO |
|
RGD |
PMID:16274362 |
RGD:1581190 |
NCBI chrNW_004936512:10,420,847...10,430,813
Ensembl chrNW_004936512:10,420,804...10,430,881
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G |
Socs1 |
suppressor of cytokine signaling 1 |
treatment |
ISO |
associated with liver cirrhosis;DNA:altered methylation:liver: DNA:hypermethylation:CpG island, 5'untranslated region: |
RGD |
PMID:14614012 PMID:15235874 PMID:18843197 PMID:22318090 |
RGD:150573687 RGD:150573689 RGD:150573700 RGD:150573703 |
NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165
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Socs2 |
suppressor of cytokine signaling 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936507:10,013,982...10,015,480
Ensembl chrNW_004936507:10,012,101...10,014,456
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G |
Socs3 |
suppressor of cytokine signaling 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16831601 |
|
NCBI chrNW_004936594:2,932,297...2,935,358
Ensembl chrNW_004936594:2,933,747...2,934,451
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G |
Sod1 |
superoxide dismutase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33010264 |
|
NCBI chrNW_004936500:10,345,154...10,352,873
Ensembl chrNW_004936500:10,345,154...10,352,867
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G |
Sod2 |
superoxide dismutase 2 |
susceptibility disease_progression |
ISO |
associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human) CTD Direct Evidence: marker/mechanism protein:increased expression:saliva |
RGD CTD |
PMID:15869407 PMID:16767786 PMID:18760346 PMID:19731237 PMID:21472284 PMID:27221200 PMID:31041878 PMID:33010264 More...
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RGD:1581242 RGD:26923907 RGD:26923955 RGD:27095881 |
NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
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G |
Sox30 |
SRY-box transcription factor 30 |
disease_progression exacerbates |
ISO |
|
RGD |
PMID:30312695 |
RGD:151660341 |
NCBI chrNW_004936515:5,501,315...5,537,946
Ensembl chrNW_004936515:5,458,393...5,537,946
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G |
Spag9 |
sperm associated antigen 9 |
|
ISO |
associated with Human Viral Hepatitis |
RGD |
PMID:29344208 |
RGD:30296654 |
NCBI chrNW_004936490:10,663,155...10,796,658
Ensembl chrNW_004936490:10,663,122...10,799,474
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G |
Spc25 |
SPC25 component of NDC80 kinetochore complex |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936469:10,628,235...10,652,168
Ensembl chrNW_004936469:10,628,230...10,652,232
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G |
Spock1 |
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 |
ameliorates |
ISO |
human cells in mouse model |
RGD |
PMID:30710422 |
RGD:153344549 |
NCBI chrNW_004936597:4,000,433...4,493,920
Ensembl chrNW_004936597:4,000,400...4,156,221
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G |
Spop |
speckle type BTB/POZ protein |
exacerbates |
ISO |
mRNA:decreased expression:liver (human) human cells in mouse model |
RGD |
PMID:26156804 PMID:33209975 |
RGD:11074965 RGD:153298924 |
NCBI chrNW_004936490:11,894,449...11,969,730
Ensembl chrNW_004936490:11,894,406...11,970,155
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G |
Spp1 |
secreted phosphoprotein 1 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:16047475 PMID:35693827 |
RGD:153344586 RGD:1581375 |
NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
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G |
Sprtn |
SprT-like N-terminal domain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25261934 |
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NCBI chrNW_004936484:19,391,685...19,402,938
Ensembl chrNW_004936484:19,391,420...19,402,944
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
disease_progression |
ISO |
|
RGD |
PMID:9581679 |
RGD:150521543 |
NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14563831 PMID:21147110 |
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NCBI chrNW_004936741:1,408,669...1,419,717
Ensembl chrNW_004936741:1,406,521...1,419,776
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G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
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NCBI chrNW_004936492:115,923...174,614
Ensembl chrNW_004936492:115,821...174,775
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G |
Srf |
serum response factor |
|
ISO |
|
RGD |
PMID:9570363 |
RGD:1581428 |
NCBI chrNW_004936476:16,779,941...16,789,499
Ensembl chrNW_004936476:16,782,233...16,789,130
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G |
Srpx |
sushi repeat containing protein X-linked |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936502:5,010,692...5,107,221
Ensembl chrNW_004936502:5,010,682...5,107,254
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G |
Srsf1 |
serine and arginine rich splicing factor 1 |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:23633480 |
RGD:9685423 |
NCBI chrNW_004936490:5,055,258...5,059,118
Ensembl chrNW_004936490:5,055,253...5,059,116
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G |
Srsf2 |
serine and arginine rich splicing factor 2 |
disease_progression treatment |
ISO |
|
RGD |
PMID:28082404 PMID:29278882 PMID:32372053 |
RGD:150429663 RGD:150429666 RGD:150429692 |
NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164
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G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
|
ISO |
protein:increased activity:liver: |
RGD |
PMID:9331085 |
RGD:10043141 |
NCBI chrNW_004936578:2,966,690...3,107,237
Ensembl chrNW_004936578:2,966,694...3,003,970
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G |
Stab2 |
stabilin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936492:10,678,074...10,817,870
Ensembl chrNW_004936492:10,678,115...10,833,963
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G |
Stat1 |
signal transducer and activator of transcription 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22488367 |
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NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756
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G |
Stat3 |
signal transducer and activator of transcription 3 |
|
ISO |
protein:increased phosphorylation:liver (mouse) |
RGD |
PMID:28100771 |
RGD:127285675 |
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
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G |
Stat4 |
signal transducer and activator of transcription 4 |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human) |
CTD RGD |
PMID:23242368 PMID:26745093 |
RGD:11553302 |
NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689
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G |
Stc2 |
stanniocalcin 2 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936609:2,319,546...2,331,049
Ensembl chrNW_004936609:2,319,111...2,332,988
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G |
Stim1 |
stromal interaction molecule 1 |
|
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:23211538 |
RGD:152995401 |
NCBI chrNW_004936498:849,775...1,063,552
Ensembl chrNW_004936498:849,739...1,063,552
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G |
Stmn1 |
stathmin 1 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:28284560 PMID:28982915 |
RGD:21408578 |
NCBI chrNW_004936474:10,470,006...10,475,557
Ensembl chrNW_004936474:10,468,728...10,475,594
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G |
Tacc3 |
transforming acidic coiled-coil containing protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936477:21,648,958...21,665,855
Ensembl chrNW_004936477:21,648,716...21,665,625
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G |
Tagln2 |
transgelin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936740:689,745...697,145
Ensembl chrNW_004936740:689,595...699,763
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G |
Taldo1 |
transaldolase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19436114 |
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NCBI chrNW_004936888:531,002...540,194
Ensembl chrNW_004936888:531,020...540,820
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G |
Tatdn1 |
TatD DNase domain containing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936470:23,123,693...23,156,764
Ensembl chrNW_004936470:23,123,730...23,167,274
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G |
Tbx3 |
T-box transcription factor 3 |
disease_progression ameliorates severity |
ISO |
protein:increased expression:liver (human) human cells in mouse model |
RGD |
PMID:22811581 PMID:26922018 PMID:29295731 PMID:30578408 PMID:33577921 |
RGD:151361112 RGD:151361114 RGD:151361122 RGD:151361123 RGD:151361132 |
NCBI chrNW_004936558:7,230,361...7,243,651
Ensembl chrNW_004936558:7,230,668...7,244,361
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Tcf19 |
transcription factor 19 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936837:821,884...825,766
Ensembl chrNW_004936837:821,861...826,088
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Tcim |
transcriptional and immune response regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936843:485,453...486,895
Ensembl chrNW_004936843:486,387...486,707
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G |
Tedc2 |
tubulin epsilon and delta complex 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936694:1,591,392...1,595,693
Ensembl chrNW_004936694:1,590,919...1,595,719
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G |
Tek |
TEK receptor tyrosine kinase |
|
ISO |
protein:increased expression |
RGD |
PMID:16951510 |
RGD:1601490 |
NCBI chrNW_004936611:2,420,176...2,531,726
Ensembl chrNW_004936611:2,420,172...2,531,722
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G |
Tep1 |
telomerase associated protein 1 |
susceptibility disease_progression |
ISO |
DNA:SNP:intron:rs1760893(human) associated with hepatitis B;DNA:SNPs: :rs1713449,rs1760898, rs872072 (human) |
RGD |
PMID:23907815 PMID:27305982 |
RGD:152975963 RGD:152977750 |
NCBI chrNW_004936877:575,264...613,965
Ensembl chrNW_004936877:575,037...641,642
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Tert |
telomerase reverse transcriptase |
disease_progression susceptibility no_association treatment |
ISO |
DNA:mutations:promoter: associated with hepatitis B;DNA:SNP: :rs13167280 (human) ClinVar Annotator: match by term: Hepatocellular carcinoma DNA:SNPs::rs2736098(human) DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human) DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human |
RGD ClinVar |
PMID:17175353 PMID:19184104 PMID:23000435 PMID:23907815 PMID:25123086 PMID:25339005 PMID:25741868 PMID:26575952 PMID:28416747 PMID:28492532 PMID:28677271 More...
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RGD:11564803 RGD:14696767 RGD:14696768 RGD:14696769 RGD:14696770 RGD:150530496 RGD:152975963 |
NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697
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G |
Tet2 |
tet methylcytosine dioxygenase 2 |
ameliorates severity disease_progression |
ISO |
human cells in mouse model mRNA, protein:decreased expression:liver (human) mRNA, protein:increased expression:liver (human) mRNA:decreased expression:liver (human) |
RGD |
PMID:26366235 PMID:29331390 PMID:30070373 PMID:33097695 |
RGD:150429595 RGD:150429597 RGD:150429684 RGD:150429689 |
NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615
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Tfpi2 |
tissue factor pathway inhibitor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17464989 PMID:28284560 |
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NCBI chrNW_004936803:69,296...90,270
Ensembl chrNW_004936803:73,946...90,295
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G |
Tfrc |
transferrin receptor |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:16953838 |
RGD:2292036 |
NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543
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Tgfa |
transforming growth factor alpha |
|
ISO |
associated with Diabetes Mellitus, Experimental CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:9029167 PMID:9060843 PMID:15565109 |
RGD:2317471 |
NCBI chrNW_004936491:14,659,089...14,758,614
Ensembl chrNW_004936491:14,657,100...14,758,848
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G |
Tgfb1 |
transforming growth factor beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (mouse) |
CTD RGD |
PMID:9029167 PMID:28100771 |
RGD:127285675 |
NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
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G |
Tgfb2 |
transforming growth factor beta 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33010264 |
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NCBI chrNW_004936628:310,720...394,002
Ensembl chrNW_004936628:308,691...394,007
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G |
Tgfbr2 |
transforming growth factor beta receptor 2 |
|
ISO |
mRNA, protein:decreased expression:liver |
RGD |
PMID:14585397 |
RGD:1601598 |
NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430
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G |
Tgm3 |
transglutaminase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936485:16,259,197...16,325,167
Ensembl chrNW_004936485:16,259,643...16,296,783
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Th |
tyrosine hydroxylase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
|
NCBI chrNW_004936794:478,651...486,887
Ensembl chrNW_004936794:478,614...487,061
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G |
Them4 |
thioesterase superfamily member 4 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:23392203 |
|
NCBI chrNW_004936580:2,058,960...2,085,919
Ensembl chrNW_004936580:2,058,643...2,085,945
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G |
Thy1 |
Thy-1 cell surface antigen |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936542:4,323,905...4,329,940
Ensembl chrNW_004936542:4,323,408...4,330,077
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G |
Ticrr |
TOPBP1 interacting checkpoint and replication regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936483:15,381,486...15,422,600
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G |
Timd4 |
T cell immunoglobulin and mucin domain containing 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936515:6,106,991...6,141,027
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G |
Tk1 |
thymidine kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936594:2,784,891...2,794,693
Ensembl chrNW_004936594:2,784,226...2,794,830
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G |
Tlr2 |
toll like receptor 2 |
susceptibility |
ISO |
DNA:deletion:promoter:-196 to -174(human) associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human) |
RGD |
PMID:21500195 PMID:22859216 PMID:27183918 |
RGD:15090813 RGD:15090815 RGD:18337266 |
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
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Tlr3 |
toll like receptor 3 |
disease_progression |
ISO |
|
RGD |
PMID:23197495 |
RGD:21079421 |
NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907
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G |
Tlr4 |
toll like receptor 4 |
susceptibility |
ISO |
DNA:SNPs, haplotype: :multiples CTD Direct Evidence: marker/mechanism protein:increased expression:liver: DNA:SNP: :rs1057317(human) |
RGD CTD |
PMID:21559380 PMID:25179842 PMID:27022031 PMID:28578348 |
RGD:14700552 RGD:14700557 RGD:14700558 |
NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
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Tlr7 |
toll like receptor 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24990399 |
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NCBI chrNW_004936470:2,593,544...2,610,972
Ensembl chrNW_004936470:2,607,508...2,610,675
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G |
Tmem70 |
transmembrane protein 70 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27914986 |
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NCBI chrNW_004936648:2,636,667...2,650,311
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G |
Tnf |
tumor necrosis factor |
disease_progression |
ISO |
mRNA, protein:increased expression:liver, blood serum (mouse) CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:26569409 PMID:26890368 PMID:27022031 |
RGD:11344640 RGD:14975171 |
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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G |
Tnfaip3 |
TNF alpha induced protein 3 |
ameliorates sexual_dimorphism |
ISO |
mRNA:decreased expression:liver (human) mRNA,protein:increased expression:liver (human) protein:decreased expression:liver (human) |
RGD |
PMID:26538215 PMID:27253414 PMID:29190981 PMID:32015333 |
RGD:151347600 RGD:151347604 RGD:151347618 RGD:151347622 |
NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345
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G |
Tnfsf10 |
TNF superfamily member 10 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:17326159 |
|
NCBI chrNW_004936593:212,642...230,645
Ensembl chrNW_004936593:212,532...230,651
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G |
Tnfsf9 |
TNF superfamily member 9 |
|
ISO |
|
RGD |
PMID:17325342 |
RGD:2317348 |
NCBI chrNW_004936588:3,844,924...3,847,218
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G |
Tnik |
TRAF2 and NCK interacting kinase |
disease_progression |
ISO |
protein:increased phosphorylation:liver, nucleus (human) |
RGD |
PMID:25160513 |
RGD:151347837 |
NCBI chrNW_004936593:1,166,995...1,546,253
Ensembl chrNW_004936593:1,167,395...1,540,399
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G |
Tonsl |
tonsoku like, DNA repair protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936470:7,817,444...7,829,124
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G |
Top2a |
DNA topoisomerase II alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
|
NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978
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G |
Tp53 |
tumor protein p53 |
treatment |
ISO |
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma | ClinVar Annotator: match by term: LIVER CELL CARCINOMA |
RGD ClinVar OMIM |
PMID:253702 PMID:960674 PMID:1349102 PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1591732 PMID:1631137 PMID:1631151 PMID:1672732 PMID:1673792 PMID:1679237 PMID:1683921 PMID:1686725 PMID:1849234 PMID:1915267 PMID:1918170 PMID:1975675 PMID:1978757 PMID:1999338 PMID:2046748 PMID:2259385 PMID:2531845 PMID:2554494 PMID:2654466 PMID:4122735 PMID:6736287 PMID:7478555 PMID:7565304 PMID:7651740 PMID:7707106 PMID:7718482 PMID:7732013 PMID:7737263 PMID:7750099 PMID:7761089 PMID:7783166 PMID:7791795 PMID:7881428 PMID:7885831 PMID:7887414 PMID:7969167 PMID:8001119 PMID:8023157 PMID:8062826 PMID:8080050 PMID:8099841 PMID:8118819 PMID:8164043 PMID:8242631 PMID:8242752 PMID:8276238 PMID:8308926 PMID:8336941 PMID:8344492 PMID:8364550 PMID:8401536 PMID:8402598 PMID:8423216 PMID:8425176 PMID:8464896 PMID:8479749 PMID:8527048 PMID:8550239 PMID:8631304 PMID:8633021 PMID:8649776 PMID:8718514 PMID:8825920 PMID:8829627 PMID:8829653 PMID:8843196 PMID:8869100 PMID:9047394 PMID:9049183 PMID:9049184 PMID:9150393 PMID:9218725 PMID:9242456 PMID:9268986 PMID:9290701 PMID:9364015 PMID:9399658 PMID:9399838 PMID:9405613 PMID:9407971 PMID:9472631 PMID:9482117 PMID:9525742 PMID:9546439 PMID:9569050 PMID:9572492 PMID:9598730 PMID:9607760 PMID:9627118 PMID:9632751 PMID:9662334 PMID:9667734 PMID:9704930 PMID:9825943 PMID:9839505 PMID:9891044 PMID:10064694 PMID:10089074 PMID:10229196 PMID:10366100 PMID:10411893 PMID:10432928 PMID:10519380 PMID:10557074 PMID:10567903 PMID:10589545 PMID:10616528 PMID:10629033 PMID:10713666 PMID:10753186 PMID:10754498 PMID:10761705 PMID:10797439 PMID:10802655 PMID:10864200 PMID:10871862 PMID:10914716 PMID:10922393 PMID:11051239 PMID:11051241 PMID:11101847 PMID:11139324 PMID:11152481 PMID:11180592 PMID:11313981 PMID:11315715 PMID:11370630 PMID:11403041 PMID:11429705 PMID:11479205 PMID:11494139 PMID:11590071 PMID:11593407 PMID:11668501 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11900253 PMID:11920788 PMID:11920959 PMID:12007217 PMID:12034820 PMID:12076704 PMID:12124823 PMID:12406399 PMID:12506399 PMID:12509279 PMID:12567188 PMID:12619118 PMID:12672316 PMID:12695689 PMID:12700230 PMID:12726864 PMID:12779080 PMID:12782597 PMID:12792784 PMID:12826609 PMID:12885464 PMID:12901974 PMID:12909720 PMID:12917626 PMID:14559903 PMID:14584079 PMID:14673037 PMID:14743206 PMID:15004724 PMID:15017592 PMID:15037740 PMID:15060172 PMID:15077194 PMID:15161705 PMID:15221755 PMID:15308588 PMID:15355915 PMID:15381368 PMID:15390294 PMID:15541116 PMID:15564800 PMID:15580553 PMID:15607980 PMID:15607981 PMID:15611505 PMID:15703170 PMID:15722483 PMID:15781620 PMID:15825182 PMID:15850016 PMID:15925506 PMID:15951970 PMID:15958617 PMID:15977174 PMID:15982667 PMID:16000567 PMID:16199549 PMID:16206219 PMID:16209708 PMID:16247456 PMID:16258005 PMID:16288208 PMID:16322298 PMID:16337994 PMID:16401470 PMID:16474844 PMID:16489069 PMID:16494995 PMID:16508005 PMID:16551709 PMID:16633321 PMID:16682957 PMID:16736287 PMID:16741917 PMID:16754663 PMID:16778209 PMID:16818505 PMID:16827139 PMID:16861262 PMID:16964264 PMID:16969106 PMID:17015838 PMID:17170001 PMID:17308077 PMID:17311302 PMID:17390010 PMID:17401428 PMID:17417627 PMID:17427234 PMID:17530187 PMID:17535973 PMID:17540308 PMID:17541742 PMID:17567834 PMID:17572079 PMID:17599946 PMID:17606709 PMID:17636407 PMID:17638920 PMID:17724467 PMID:17875924 PMID:17881637 PMID:17974978 PMID:17999388 PMID:18208484 PMID:18307025 PMID:18391940 PMID:18453682 PMID:18477611 PMID:18511570 PMID:18555592 PMID:18628487 PMID:18685109 PMID:18689542 PMID:18818522 PMID:18937320 PMID:19012332 PMID:19101993 PMID:19127115 PMID:19147582 PMID:19171880 PMID:19336573 PMID:19367287 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19454241 PMID:19462533 PMID:19468865 PMID:19521721 PMID:19556618 PMID:19681600 PMID:19711436 PMID:19714490 PMID:19834951 PMID:19850740 PMID:19881536 PMID:19913028 PMID:19930417 PMID:20013323 PMID:20028212 PMID:20113312 PMID:20118236 PMID:20127978 PMID:20128691 PMID:20182602 PMID:20234365 PMID:20308654 PMID:20407015 PMID:20436704 PMID:20505364 PMID:20506564 PMID:20516128 PMID:20520810 PMID:20522432 PMID:20538734 PMID:20586629 PMID:20589832 PMID:20593220 PMID:20689556 PMID:20693561 PMID:20805372 PMID:20878954 PMID:20972454 PMID:21056685 PMID:21059199 PMID:21080251 PMID:21113594 PMID:21115975 PMID:21118481 PMID:21159183 PMID:21187651 PMID:21232794 PMID:21305319 PMID:21343334 PMID:21356188 PMID:21445056 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21535297 PMID:21552135 PMID:21561095 PMID:21590121 PMID:21601526 PMID:21619694 PMID:21626334 PMID:21665182 PMID:21672450 PMID:21674059 PMID:21747090 PMID:21761402 PMID:22006311 PMID:22052707 PMID:22090360 PMID:22110706 PMID:22114072 PMID:22186996 PMID:22198284 PMID:22233476 PMID:22265402 PMID:22319594 PMID:22427690 PMID:22484423 PMID:22553421 PMID:22553460 PMID:22672556 PMID:22698404 PMID:22703879 PMID:22710932 PMID:22713868 PMID:22729912 PMID:22744426 PMID:22768918 PMID:22811390 PMID:22822097 PMID:22862161 PMID:22869713 PMID:22887876 PMID:22899716 PMID:22915647 PMID:22919068 PMID:22923379 PMID:22955915 PMID:22983585 PMID:22999923 PMID:23028800 PMID:23031740 PMID:23161690 PMID:23172776 PMID:23246812 PMID:23259501 PMID:23263379 PMID:23265383 PMID:23315175 PMID:23334668 PMID:23406775 PMID:23484829 PMID:23538418 PMID:23612969 PMID:23624782 PMID:23625637 PMID:23630318 PMID:23667202 PMID:23713777 PMID:23792586 PMID:23887774 PMID:23894400 PMID:23939625 PMID:23950206 PMID:23967324 PMID:24033266 PMID:24038938 PMID:24065105 PMID:24122735 PMID:24307375 PMID:24381225 PMID:24382691 PMID:24384472 PMID:24395441 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24590827 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24702488 PMID:24728327 PMID:24744791 PMID:24810334 PMID:24835218 PMID:24857548 PMID:24940547 PMID:25059482 PMID:25119136 PMID:25123297 PMID:25131192 PMID:25157968 PMID:25186627 PMID:25256166 PMID:25293557 PMID:25294809 PMID:25326637 PMID:25339994 PMID:25404506 PMID:25433984 PMID:25503501 PMID:25504633 PMID:25516983 PMID:25525159 PMID:25584008 PMID:25584637 PMID:25612911 PMID:25619955 PMID:25634208 PMID:25691460 PMID:25741868 PMID:25757876 PMID:25765855 PMID:25787918 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:25980754 PMID:26014290 PMID:26024390 PMID:26066407 PMID:26205489 PMID:26225655 PMID:26230955 PMID:26270727 PMID:26271412 PMID:26332594 PMID:26425688 PMID:26467025 PMID:26497680 PMID:26554828 PMID:26556299 PMID:26580448 PMID:26585234 PMID:26619011 PMID:26628864 PMID:26641009 PMID:26659639 PMID:26681312 PMID:26718964 PMID:26781615 PMID:26786923 PMID:26787237 PMID:26818906 PMID:26822237 PMID:26845104 PMID:26878390 PMID:26911350 PMID:26976419 PMID:27022024 PMID:27077130 PMID:27146902 PMID:27149858 PMID:27153395 PMID:27179933 PMID:27189670 PMID:27276561 PMID:27276934 PMID:27328919 PMID:27374712 PMID:27458004 PMID:27463065 PMID:27489289 PMID:27493922 PMID:27501770 PMID:27516001 PMID:27523101 PMID:27533082 PMID:27557517 PMID:27616075 PMID:27621308 PMID:27622479 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27730344 PMID:27813088 PMID:27873457 PMID:27895058 PMID:27911860 PMID:27959731 PMID:27993330 PMID:28135145 PMID:28152038 PMID:28160093 PMID:28166194 PMID:28176830 PMID:28271309 PMID:28279309 PMID:28349240 PMID:28356770 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28477316 PMID:28492532 PMID:28664506 PMID:28724667 PMID:28772286 PMID:28802053 PMID:28861920 PMID:28873162 PMID:28949402 PMID:28975465 PMID:29025599 PMID:29058119 PMID:29070607 PMID:29076966 PMID:29126202 PMID:29300620 PMID:29324801 PMID:29470806 PMID:29478780 PMID:29489754 PMID:29581140 PMID:29752822 PMID:29753700 PMID:29785153 PMID:29958926 PMID:29979965 PMID:30076369 PMID:30093976 PMID:30107044 PMID:30128536 PMID:30152528 PMID:30216591 PMID:30224644 PMID:30287823 PMID:30299350 PMID:30311369 PMID:30318520 PMID:30322717 PMID:30327374 PMID:30352134 PMID:30374176 PMID:30450585 PMID:30546832 PMID:30583724 PMID:30630526 PMID:30675318 PMID:30709381 PMID:30720243 PMID:30816478 PMID:30840781 PMID:30918304 PMID:31016814 PMID:31050713 PMID:31105275 PMID:31119730 PMID:31121848 PMID:31127191 PMID:31159747 PMID:31168460 PMID:31206626 PMID:31212162 PMID:31296311 PMID:31300551 PMID:31321604 PMID:31494577 PMID:31559875 PMID:31742824 PMID:31748977 PMID:31775759 PMID:31882575 PMID:31983162 PMID:32000721 PMID:32019277 PMID:32126783 PMID:32156018 PMID:32164171 PMID:32179180 PMID:32187361 PMID:32295079 PMID:32318955 PMID:32371905 PMID:32401780 PMID:32475984 PMID:32658383 PMID:32817165 PMID:32885271 PMID:32888145 PMID:32899294 PMID:32906206 PMID:32959997 PMID:32980694 PMID:33087929 PMID:33138793 PMID:33163847 PMID:33208383 PMID:33245408 PMID:33257846 PMID:33300245 PMID:33332384 PMID:33372952 PMID:33407742 PMID:33471991 PMID:33633026 PMID:33635883 PMID:33674644 PMID:33818021 PMID:33840814 PMID:33841550 PMID:34026625 PMID:34088725 PMID:34240179 PMID:34266904 PMID:34299313 PMID:34308366 PMID:34503094 PMID:34529667 PMID:34675114 PMID:34709361 PMID:34793666 PMID:34805717 PMID:34994652 PMID:35033608 PMID:35043155 PMID:35127508 PMID:35802772 PMID:35820297 PMID:35938033 PMID:35974385 PMID:36008825 PMID:36219266 PMID:36309086 PMID:36329109 PMID:36988593 More...
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RGD:152998960 |
NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
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G |
Tp73 |
tumor protein p73 |
treatment exacerbates |
ISO |
mRNA:increased expression:liver (human) human cells in a mouse model protein:decreased phosphorylation:liver (human) |
RGD |
PMID:14760085 PMID:19664633 PMID:25371988 PMID:27359056 PMID:31429776 |
RGD:151347579 RGD:151347592 RGD:151347593 RGD:151347594 RGD:151347596 |
NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464
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G |
Tpx2 |
TPX2 microtubule nucleation factor |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936485:18,718,801...18,773,315
Ensembl chrNW_004936485:18,718,795...18,767,951
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G |
Traf7 |
TNF receptor associated factor 7 |
treatment |
ISO |
mRNA:increased expression:liver |
RGD |
PMID:31730901 |
RGD:151356961 |
NCBI chrNW_004936694:1,868,309...1,886,772
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G |
Traip |
TRAF interacting protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936529:1,434,629...1,466,382
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G |
Trim24 |
tripartite motif containing 24 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18026104 |
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NCBI chrNW_004936592:2,902,805...2,962,602
Ensembl chrNW_004936592:2,863,743...2,963,977
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G |
Trip13 |
thyroid hormone receptor interactor 13 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936815:734,029...745,381
Ensembl chrNW_004936815:734,167...745,092
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G |
Troap |
trophinin associated protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936512:7,079,485...7,086,382
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G |
Tsc1 |
TSC complex subunit 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21499249 |
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NCBI chrNW_004936487:19,331,183...19,386,841
Ensembl chrNW_004936487:19,331,194...19,386,892
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G |
Tsc2 |
TSC complex subunit 2 |
severity |
ISO |
protein:decreased expression:liver (human) |
RGD |
PMID:24119083 |
RGD:21079731 |
NCBI chrNW_004936694:1,958,152...1,993,373
Ensembl chrNW_004936694:1,958,154...1,993,363
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G |
Tslp |
thymic stromal lymphopoietin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936531:5,495,872...5,500,462
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G |
Tst |
thiosulfate sulfurtransferase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21472284 |
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NCBI chrNW_004936492:3,880,545...3,886,881
Ensembl chrNW_004936492:3,880,500...3,886,950
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G |
Ttc36 |
tetratricopeptide repeat domain 36 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936542:3,567,469...3,571,393
Ensembl chrNW_004936542:3,566,876...3,571,504
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G |
Ttk |
TTK protein kinase |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (human) |
CTD RGD |
PMID:28284560 PMID:35693827 |
RGD:153344586 |
NCBI chrNW_004936510:10,176,968...10,213,483
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G |
Ttr |
transthyretin |
disease_progression |
ISO |
protein:decreased expression:blood serum (human) protein:increased expression:blood serum (human) protein:increased expression:blood serum (rat) |
RGD |
PMID:16240287 PMID:28876464 PMID:29534342 |
RGD:151356736 RGD:151664602 RGD:151665161 |
NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566
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G |
Txnip |
thioredoxin interacting protein |
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ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936867:722,544...726,595
Ensembl chrNW_004936867:722,514...726,617
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G |
Tyms |
thymidylate synthetase |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism DNA:deletion:3'UTR:1494del6(human) |
CTD RGD |
PMID:17659576 PMID:18019677 PMID:18230555 |
RGD:14696708 |
NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840
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G |
Uaca |
uveal autoantigen with coiled-coil domains and ankyrin repeats |
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ISO |
OMIM:114550 |
MouseDO |
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NCBI chrNW_004936471:30,213,742...30,312,873
Ensembl chrNW_004936471:30,211,588...30,363,992
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G |
Ubd |
ubiquitin D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19363144 |
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NCBI chrNW_004936723:1,218,621...1,221,070
Ensembl chrNW_004936723:1,218,258...1,221,451
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G |
Ube2c |
ubiquitin conjugating enzyme E2 C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936514:7,204,332...7,208,340
Ensembl chrNW_004936514:7,199,539...7,207,655
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G |
Ube2e2 |
ubiquitin conjugating enzyme E2 E2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27914986 |
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NCBI chrNW_004936473:14,988,802...15,280,650
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G |
Ube2t |
ubiquitin conjugating enzyme E2 T |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936567:2,222,317...2,226,725
Ensembl chrNW_004936567:2,222,317...2,226,678
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G |
Ubr5 |
ubiquitin protein ligase E3 component n-recognin 5 |
treatment |
ISO |
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RGD |
PMID:32087767 |
RGD:151665344 |
NCBI chrNW_004936470:41,222,782...41,345,755
Ensembl chrNW_004936470:41,252,951...41,344,134
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18666234 |
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NCBI chrNW_004936482:8,551,749...8,563,586
Ensembl chrNW_004936482:8,551,603...8,563,651
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G |
Uhrf1 |
ubiquitin like with PHD and ring finger domains 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936588:2,863,651...2,890,116
Ensembl chrNW_004936588:2,862,367...2,888,946
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G |
Umps |
uridine monophosphate synthetase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18230555 |
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NCBI chrNW_004936725:553,278...564,846
Ensembl chrNW_004936725:549,804...565,141
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G |
Usp2 |
ubiquitin specific peptidase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21147110 |
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NCBI chrNW_004936542:4,284,243...4,310,545
Ensembl chrNW_004936542:4,285,819...4,307,925
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G |
Usp4 |
ubiquitin specific peptidase 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35841383 |
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NCBI chrNW_004936529:941,042...989,781
Ensembl chrNW_004936529:938,501...989,884
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G |
Vasn |
vasorin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25826090 |
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NCBI chrNW_004936694:128,398...138,954
Ensembl chrNW_004936694:128,273...138,954
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G |
Vav1 |
vav guanine nucleotide exchange factor 1 |
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ISO |
mRNA:decreased expression:liver |
RGD |
PMID:2064726 |
RGD:2306008 |
NCBI chrNW_004936588:4,058,312...4,107,330
Ensembl chrNW_004936588:4,058,343...4,107,109
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22922871 |
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NCBI chrNW_004936748:785,491...802,791
Ensembl chrNW_004936748:785,455...803,048
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Vdr |
vitamin D receptor |
susceptibility |
ISO |
associated with alcoholic liver cirrhosis;DNA:haplotype:: ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human) |
RGD ClinVar |
PMID:20572305 PMID:24033266 PMID:25541958 PMID:25741868 PMID:28492532 |
RGD:14402025 RGD:14402026 |
NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109
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Vegfa |
vascular endothelial growth factor A |
treatment susceptibility disease_progression |
ISO |
protein:increased expression:liver DNA:SNP: :2578C>A (human) associated with liver cirrhosis; associated with liver cirrhosis; protein:increased expression:platelet, liver: protein:increased expression:serum: DNA:polymorphism:promoter:-2578C>A (rs699947)(human) |
RGD |
PMID:16835748 PMID:18392108 PMID:18544126 PMID:24445728 PMID:25999787 PMID:26930285 PMID:27338800 PMID:28147320 More...
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RGD:11527070 RGD:126848814 RGD:15003194 RGD:15003196 RGD:15003200 RGD:15014783 RGD:15036790 RGD:152177911 |
NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
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Vegfc |
vascular endothelial growth factor C |
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ISO |
associated with liver cirrhosis; protein:increased expression:liver: |
RGD |
PMID:18544126 |
RGD:15003200 |
NCBI chrNW_004936516:7,217,543...7,332,531
Ensembl chrNW_004936516:7,217,543...7,332,559
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Vhl |
von Hippel-Lindau tumor suppressor |
disease_progression |
ISO |
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RGD |
PMID:31321740 |
RGD:155882550 |
NCBI chrNW_004936602:3,135,790...3,140,622
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G |
Vipr1 |
vasoactive intestinal peptide receptor 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936695:2,564,917...2,597,009
Ensembl chrNW_004936695:2,564,890...2,607,676
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G |
Vsig4 |
V-set and immunoglobulin domain containing 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936635:2,167,633...2,191,725
Ensembl chrNW_004936635:2,167,617...2,191,740
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G |
Wdr62 |
WD repeat domain 62 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936922:80,136...119,702
Ensembl chrNW_004936922:80,217...119,653
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G |
Wdr76 |
WD repeat domain 76 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936471:6,878,350...6,923,951
Ensembl chrNW_004936471:6,878,584...6,923,921
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G |
Wnt2 |
Wnt family member 2 |
susceptibility |
ISO |
associated with hepatitis B;DNA:SNP: :rs4730775(human) |
RGD |
PMID:28328801 |
RGD:14402040 |
NCBI chrNW_004936589:1,825,209...1,866,898
Ensembl chrNW_004936589:1,825,209...1,866,889
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G |
Wrap53 |
WD repeat containing antisense to TP53 |
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ISO |
RNA:increased expression:liver: |
RGD |
PMID:26551349 |
RGD:11096781 |
NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791
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Xdh |
xanthine dehydrogenase |
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ISO |
protein:decreased activity:tumor (rat) |
RGD |
PMID:179860 |
RGD:5135059 |
NCBI chrNW_004936493:1,762,814...1,824,501
Ensembl chrNW_004936493:1,762,869...1,823,238
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Xpo1 |
exportin 1 |
ameliorates exacerbates treatment |
ISO |
human cell line in a mouse model mRNA:increased expression:liver (human) |
RGD |
PMID:25030088 PMID:27013579 PMID:31371628 |
RGD:151665796 RGD:151667433 RGD:151667441 |
NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343
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Xpo5 |
exportin 5 |
severity |
ISO |
DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) |
RGD |
PMID:24676133 |
RGD:11041737 |
NCBI chrNW_004936476:16,434,629...16,481,044
Ensembl chrNW_004936476:16,434,638...16,481,044
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Xrcc1 |
X-ray repair cross complementing 1 |
susceptibility severity disease_progression no_association |
ISO |
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human) DNA:SNPs:exon 9, exon 15: c.910A>G, c.1686C>G (human) associated with Chronic Hepatitis C;DNA:SNP:exon 14: c.1517G>C, p.506G>A (human) DNA:SNP:exon 13: c.1471G>A, p.E491K (human) DNA:SNPs:cds: 194C>T, 280A>G (human) associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human) DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human) DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human) DNA:missense mutation:cds:p.R399Q (human) DNA:missense mutation:cds:p.R399Q (rs25487) (human) associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human) DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human) DNA:SNPs:exons:c.1254C>T, c.1517G>C (human) associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human) DNA:missense mutation:cds:c.1804C>A (p.G506A) (human) |
RGD |
PMID:14519756 PMID:19194663 PMID:22502666 PMID:23454624 PMID:23493666 PMID:23534753 PMID:23984316 PMID:24446299 PMID:24526467 PMID:24570146 PMID:24634229 PMID:26918371 PMID:28058700 PMID:28927037 PMID:29682247 PMID:29935355 PMID:32334466 More...
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RGD:14696702 RGD:14696772 RGD:14696773 RGD:14985238 RGD:14985240 RGD:14985242 RGD:14985243 RGD:15014789 RGD:15014790 RGD:15014791 RGD:15014792 RGD:15036794 RGD:15036797 RGD:150530503 RGD:150530624 RGD:150540332 RGD:150540333 |
NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777
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Yap1 |
Yes1 associated transcriptional regulator |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29698666 |
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NCBI chrNW_004936551:5,638,383...5,740,523
Ensembl chrNW_004936551:5,634,751...5,740,567
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G |
Ythdf2 |
YTH N6-methyladenosine RNA binding protein F2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28104805 |
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NCBI chrNW_004936474:12,791,121...12,827,122
Ensembl chrNW_004936474:12,791,073...12,827,122
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G |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
severity |
ISO |
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RGD |
PMID:27811373 |
RGD:14700875 |
NCBI chrNW_004936470:42,444,671...42,470,548
Ensembl chrNW_004936470:42,445,412...42,470,900
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G |
Zc3h12d |
zinc finger CCCH-type containing 12D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34545456 |
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NCBI chrNW_004936489:2,454,889...2,472,392
Ensembl chrNW_004936489:2,455,728...2,472,328
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G |
Zfhx3 |
zinc finger homeobox 3 |
severity disease_progression |
ISO |
human cell line in a mouse model associated with Chronic Hepatitis B;protein:decreased expression:blood serum (human) |
RGD |
PMID:20534899 PMID:32277050 |
RGD:151361162 RGD:151361169 |
NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544
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G |
Zfp36 |
ZFP36 ring finger protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936661:2,251,148...2,253,527
Ensembl chrNW_004936661:2,250,665...2,253,787
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G |
Zic2 |
Zic family member 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936472:10,599,717...10,605,187
Ensembl chrNW_004936472:10,602,102...10,605,191
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G |
Zic4 |
Zic family member 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936519:8,007,605...8,025,831
Ensembl chrNW_004936519:8,004,926...8,025,831
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G |
Zic5 |
Zic family member 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936472:10,615,843...10,623,221
Ensembl chrNW_004936472:10,616,122...10,622,338
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G |
Znf23 |
zinc finger protein 23 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21965783 |
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NCBI chrNW_004936475:22,283,924...22,293,074
Ensembl chrNW_004936475:22,272,514...22,293,278
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G |
Zwint |
ZW10 interacting kinetochore protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28284560 |
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NCBI chrNW_004936693:1,539,987...1,551,685
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G |
Ephx1 |
epoxide hydrolase 1 |
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ISO |
associated with estrogen excess;protein:increased activity;liver (rat) |
RGD |
PMID:6133380 |
RGD:152998935 |
NCBI chrNW_004936526:2,589,254...2,652,831
Ensembl chrNW_004936526:2,614,059...2,653,286
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Ggt1 |
gamma-glutamyltransferase 1 |
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ISO |
associated with estrogen excess;protein:increased activity;liver (rat) |
RGD |
PMID:6133380 |
RGD:152998935 |
NCBI chrNW_004936619:762,278...791,610
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
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ISO |
ClinVar Annotator: match by term: Pediatric hepatocellular carcinoma |
ClinVar |
PMID:9927037 PMID:17483355 |
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NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179
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G |
Ca12 |
carbonic anhydrase 12 |
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ISO |
mRNA:increased expression:liver |
RGD |
PMID:28304380 |
RGD:153352326 |
NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987
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G |
Ctnnb1 |
catenin beta 1 |
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ISO |
protein:increased tyrosine phosphorylation:exon: |
RGD |
PMID:19101982 |
RGD:14402052 |
NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
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G |
Fgfr1 |
fibroblast growth factor receptor 1 |
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ISO |
protein:increased expression:liver: |
RGD |
PMID:24925055 |
RGD:11055933 |
NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
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ISO |
mRNA,protein:increased expression:liver (human) |
RGD |
PMID:27027723 |
RGD:151347845 |
NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
disease_progression |
ISO |
DNA:polymorphism: :rs12478635(human) DNA:misssense mutation:cds:p.Arg132Cys(human) |
RGD |
PMID:25355558 PMID:28403884 |
RGD:14974227 RGD:14974228 |
NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
disease_progression |
ISO |
DNA:polymorphism: :rs11632348(human) |
RGD |
PMID:25355558 |
RGD:14974228 |
NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
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G |
Lep |
leptin |
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ISO |
mRNA:increased expression:liver: |
RGD |
PMID:20723213 |
RGD:14696785 |
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
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G |
Lepr |
leptin receptor |
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ISO |
mRNA:increased expression:liver |
RGD |
PMID:20723213 |
RGD:14696785 |
NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444
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G |
Tert |
telomerase reverse transcriptase |
disease_progression |
ISO |
mRNA:increased expression:liver: |
RGD |
PMID:20723213 PMID:28460432 |
RGD:14696783 RGD:14696785 |
NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
susceptibility |
ISO |
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RGD |
PMID:28923495 |
RGD:151347843 |
NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753
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G |
Sprtn |
SprT-like N-terminal domain |
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ISO |
ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome | ClinVar Annotator: match by term: Ruijs-Aalfs syndrome |
OMIM ClinVar |
PMID:12503110 PMID:25261934 PMID:25741868 |
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NCBI chrNW_004936484:19,391,685...19,402,938
Ensembl chrNW_004936484:19,391,420...19,402,944
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