Fgf4 (fibroblast growth factor 4) - Rat Genome Database

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Pathways
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Gene: Fgf4 (fibroblast growth factor 4) Ictidomys tridecemlineatus
Analyze
Symbol: Fgf4
Name: fibroblast growth factor 4
RGD ID: 12623394
Description: ENCODES a protein that exhibits fibroblast growth factor receptor binding (inferred); growth factor activity (inferred); INVOLVED IN apoptotic process (ortholog); apoptotic process involved in morphogenesis (ortholog); cartilage condensation (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); Breast Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,451,742 - 4,453,375 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936599894,091 - 895,676 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fgf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,451,742 - 4,453,375 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936599894,091 - 895,676 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,771,022 - 69,775,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,771,022 - 69,775,341 (-)EnsemblGRCh38hg38GRCh38
GRCh371169,585,790 - 69,590,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,296,978 - 69,299,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 341169,296,977 - 69,299,352NCBI
Celera1166,884,811 - 66,887,185 (-)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1165,880,131 - 65,882,505 (-)NCBIHuRef
CHM1_11169,470,729 - 69,473,103 (-)NCBICHM1_1
T2T-CHM13v2.01169,787,944 - 69,792,263 (-)NCBIT2T-CHM13v2.0
Fgf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,415,123 - 144,418,982 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,401,104 - 144,418,980 (+)EnsemblGRCm39 Ensembl
GRCm387144,861,386 - 144,865,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,847,367 - 144,865,243 (+)EnsemblGRCm38mm10GRCm38
MGSCv377152,047,291 - 152,051,148 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,670,776 - 144,674,633 (+)NCBIMGSCv36mm8
Celera7144,626,624 - 144,630,481 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.88NCBI
Fgf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,453,229 - 209,457,085 (+)NCBIGRCr8
mRatBN7.21200,023,937 - 200,027,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,024,056 - 200,025,466 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,405,105 - 208,408,963 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,491,358 - 215,495,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,165,562 - 208,169,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,024,537 - 218,029,539 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,025,810 - 218,027,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,895,162 - 224,896,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,292,272 - 205,293,705 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,445,724 - 205,447,158 (+)NCBI
Celera1197,582,129 - 197,583,539 (+)NCBICelera
Cytogenetic Map1q42NCBI
Fgf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542216,362,418 - 16,364,126 (+)NCBIChiLan1.0ChiLan1.0
FGF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2970,736,483 - 70,740,546 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,779,631 - 71,783,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01164,866,649 - 64,871,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,158,485 - 68,196,616 (-)NCBIpanpan1.1PanPan1.1panPan2
FGF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,413,480 - 48,417,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,413,187 - 48,416,977 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,023,493 - 47,027,360 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01849,090,454 - 49,093,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1849,090,383 - 49,093,914 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11848,537,232 - 48,541,095 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01848,123,673 - 48,127,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01848,869,443 - 48,873,311 (+)NCBIUU_Cfam_GSD_1.0
FGF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,526,914 - 3,529,874 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,527,113 - 3,529,011 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,004,484 - 2,006,245 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,786,296 - 4,791,441 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,789,203 - 4,791,036 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038102,062,579 - 102,067,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476717,381,791 - 17,383,468 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476717,381,387 - 17,385,698 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005333313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005333313   ⟹   XP_005333370
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049474,451,742 - 4,453,375 (+)NCBI
SpeTri2.0NW_004936599894,091 - 895,676 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005333370 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017787.1
GenBank Protein KAG3284467 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005333370   ⟸   XM_005333313
- UniProtKB: I3N091 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019792 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023760.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
NCBI Gene Fgf4 ENTREZGENE
PANTHER PTHR11486 UniProtKB/TrEMBL
  PTHR11486:SF31 UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PRINTS HBGFFGF UniProtKB/TrEMBL
  IL1HBGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/TrEMBL
UniProt I3N091 ENTREZGENE, UniProtKB/TrEMBL