Zc3h12d (zinc finger CCCH-type containing 12D) - Rat Genome Database

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Gene: Zc3h12d (zinc finger CCCH-type containing 12D) Ictidomys tridecemlineatus
Analyze
Symbol: Zc3h12d
Name: zinc finger CCCH-type containing 12D
RGD ID: 12440579
Description: ENCODES a protein that exhibits endonuclease activity (inferred); metal ion binding (inferred); mRNA binding (inferred); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); mRNA catabolic process (ortholog); negative regulation of cell growth (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable ribonuclease ZC3H12D
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946135,202,865 - 135,228,936 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364892,455,728 - 2,472,328 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364892,454,889 - 2,472,392 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zc3h12d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946135,202,865 - 135,228,936 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364892,455,728 - 2,472,328 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364892,454,889 - 2,472,392 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZC3H12D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386149,446,795 - 149,485,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6149,446,795 - 149,485,014 (-)EnsemblGRCh38hg38GRCh38
GRCh376149,767,931 - 149,806,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366149,812,571 - 149,847,723 (-)NCBINCBI36Build 36hg18NCBI36
Celera6150,503,861 - 150,541,240 (-)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6147,335,524 - 147,372,891 (-)NCBIHuRef
CHM1_16150,033,515 - 150,070,897 (-)NCBICHM1_1
T2T-CHM13v2.06150,646,494 - 150,684,730 (-)NCBIT2T-CHM13v2.0
Zc3h12d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39107,708,087 - 7,746,161 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl107,708,234 - 7,746,160 (+)EnsemblGRCm39 Ensembl
GRCm38107,832,323 - 7,870,397 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl107,832,470 - 7,870,396 (+)EnsemblGRCm38mm10GRCm38
MGSCv37107,552,268 - 7,590,195 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36107,522,660 - 7,560,586 (+)NCBIMGSCv36mm8
Celera107,711,148 - 7,749,061 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.44NCBI
Zc3h12d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814,131,674 - 4,169,192 (+)NCBIGRCr8
mRatBN7.212,313,110 - 2,348,820 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl12,314,324 - 2,348,819 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx11,964,214 - 1,998,661 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.017,964,619 - 7,999,064 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.012,246,326 - 2,280,771 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.011,937,620 - 1,972,919 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl11,938,419 - 1,972,918 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013,634,641 - 3,669,534 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.412,507,365 - 2,541,861 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1863,044 - 897,549 (+)NCBICelera
Cytogenetic Map1p13NCBI
Zc3h12d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543911,768,812 - 11,785,230 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543911,761,099 - 11,787,508 (+)NCBIChiLan1.0ChiLan1.0
ZC3H12D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25169,474,368 - 169,510,614 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16167,365,292 - 167,404,189 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06147,266,039 - 147,304,289 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16151,973,996 - 152,010,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6151,974,485 - 151,999,898 (-)Ensemblpanpan1.1panPan2
ZC3H12D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1140,249,856 - 40,279,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl140,259,705 - 40,279,888 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha141,087,019 - 41,112,742 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0140,429,790 - 40,455,566 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl140,431,812 - 40,459,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1140,306,086 - 40,331,843 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0140,171,027 - 40,196,784 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0140,511,853 - 40,537,572 (-)NCBIUU_Cfam_GSD_1.0
ZC3H12D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl116,465,252 - 16,498,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1116,463,532 - 16,498,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2118,783,708 - 18,819,632 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZC3H12D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11322,152,938 - 22,195,470 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1322,158,259 - 22,194,514 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040198,177,140 - 198,214,289 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zc3h12d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247858,588,480 - 8,613,199 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013967   ⟹   ENSSTOP00000012516
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364892,455,728 - 2,472,328 (-)Ensembl
RefSeq Acc Id: XM_005321357   ⟹   XP_005321414
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946135,202,865 - 135,228,295 (-)NCBI
SpeTri2.0NW_0049364892,454,889 - 2,472,392 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040283439   ⟹   XP_040139373
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946135,202,865 - 135,228,936 (-)NCBI
RefSeq Acc Id: XM_040283440   ⟹   XP_040139374
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946135,202,865 - 135,228,936 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005321414 (Get FASTA)   NCBI Sequence Viewer  
  XP_040139373 (Get FASTA)   NCBI Sequence Viewer  
  XP_040139374 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012516.3
GenBank Protein KAG3290411 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005321414   ⟸   XM_005321357
- UniProtKB: I3MM14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040139374   ⟸   XM_040283440
- UniProtKB: I3MM14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040139373   ⟸   XM_040283439
- UniProtKB: I3MM14 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000012516   ⟸   ENSSTOT00000013967
Protein Domains
C3H1-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013975 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013967.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.11980 UniProtKB/TrEMBL
InterPro Rege-1_UBA-like UniProtKB/TrEMBL
  RNase_Zc3h12_NYN UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
NCBI Gene Zc3h12d ENTREZGENE
PANTHER N4BP1-RELATED UniProtKB/TrEMBL
  RIBONUCLEASE ZC3H12D-RELATED UniProtKB/TrEMBL
Pfam RNase_Zc3h12a UniProtKB/TrEMBL
  UBA_6 UniProtKB/TrEMBL
PROSITE ZF_C3H1 UniProtKB/TrEMBL
UniProt I3MM14 ENTREZGENE, UniProtKB/TrEMBL