Ncoa2 (nuclear receptor coactivator 2) - Rat Genome Database

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Gene: Ncoa2 (nuclear receptor coactivator 2) Ictidomys tridecemlineatus
Analyze
Symbol: Ncoa2
Name: nuclear receptor coactivator 2
RGD ID: 12487033
Description: ENCODES a protein that exhibits DNA polymerase binding (ortholog); nuclear estrogen receptor binding (ortholog); nuclear glucocorticoid receptor binding (ortholog); INVOLVED IN cellular response to Thyroglobulin triiodothyronine (ortholog); cerebellum development (ortholog); male gonad development (ortholog); PARTICIPATES IN aldosterone signaling pathway; altered androgen signaling pathway; androgen signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Breast Neoplasms (ortholog); Chronobiology Disorders (ortholog); FOUND IN dendritic spine (ortholog); RNA polymerase II transcription regulator complex (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear receptor coactivator 2, transcript variant X1; nuclear receptor coactivator 2, transcript variant X2; nuclear receptor coactivator 2, transcript variant X3; nuclear receptor coactivator 2, transcript variant X4; nuclear receptor coactivator 2, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530359,680,707 - 59,940,562 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649614,844,855 - 15,016,454 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649614,844,923 - 15,102,922 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ncoa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530359,680,707 - 59,940,562 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649614,844,855 - 15,016,454 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649614,844,923 - 15,102,922 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCOA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38870,109,782 - 70,456,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl870,109,782 - 70,403,808 (-)EnsemblGRCh38hg38GRCh38
GRCh37871,022,017 - 71,316,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,186,821 - 71,478,574 (-)NCBINCBI36Build 36hg18NCBI36
Build 34871,186,820 - 71,478,574NCBI
Celera867,021,935 - 67,313,703 (-)NCBICelera
Cytogenetic Map8q13.3NCBI
HuRef866,517,566 - 66,809,329 (-)NCBIHuRef
CHM1_1871,079,808 - 71,371,655 (-)NCBICHM1_1
T2T-CHM13v2.0870,539,621 - 70,834,144 (-)NCBIT2T-CHM13v2.0
Ncoa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,209,329 - 13,444,451 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,209,329 - 13,444,307 (-)EnsemblGRCm39 Ensembl
GRCm38113,139,105 - 13,374,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,139,105 - 13,374,083 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,129,240 - 13,364,164 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,127,689 - 13,359,278 (-)NCBIMGSCv36mm8
Celera113,103,226 - 13,334,430 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.12NCBI
Ncoa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8510,618,712 - 10,852,776 (+)NCBIGRCr8
mRatBN7.255,835,642 - 6,069,693 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl55,835,706 - 6,067,451 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx58,132,076 - 8,209,657 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.059,770,968 - 9,848,544 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.059,460,403 - 9,538,097 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.055,466,544 - 5,696,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl55,616,483 - 5,694,598 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0510,306,581 - 10,538,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.455,197,891 - 5,275,776 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.155,197,890 - 5,273,000 (+)NCBI
Celera55,570,901 - 5,648,759 (+)NCBICelera
Cytogenetic Map5q11NCBI
Ncoa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554449,313,447 - 9,584,913 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554449,313,748 - 9,587,109 (+)NCBIChiLan1.0ChiLan1.0
NCOA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2785,839,497 - 86,141,138 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1861,469,337 - 61,770,965 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0866,632,139 - 66,929,526 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1868,293,012 - 68,480,104 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl868,293,018 - 68,400,479 (-)Ensemblpanpan1.1panPan2
NCOA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12919,253,849 - 19,471,640 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2919,222,842 - 19,545,371 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2919,511,986 - 19,805,562 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02919,347,144 - 19,643,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2919,347,185 - 19,642,297 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12919,386,646 - 19,682,493 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02919,452,837 - 19,748,399 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02919,733,575 - 20,029,399 (-)NCBIUU_Cfam_GSD_1.0
NCOA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl464,954,238 - 65,246,572 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1464,888,029 - 65,245,757 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2470,584,741 - 70,791,313 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCOA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1865,855,232 - 66,151,733 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl865,855,235 - 66,040,947 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603975,279,759 - 75,586,607 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ncoa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,938,555 - 21,078,690 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,795,385 - 21,078,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000012741   ⟹   ENSSTOP00000011417
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649614,844,855 - 15,016,454 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000023665   ⟹   ENSSTOP00000021326
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649614,844,855 - 15,016,454 (-)Ensembl
RefSeq Acc Id: XM_005322988   ⟹   XP_005323045
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,847,872 - 59,940,562 (+)NCBI
SpeTri2.0NW_00493649614,844,923 - 14,937,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724924   ⟹   XP_021580599
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,846,431 - 59,936,861 (+)NCBI
SpeTri2.0NW_00493649614,848,616 - 14,939,634 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040293962   ⟹   XP_040149896
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,680,997 - 59,936,861 (+)NCBI
RefSeq Acc Id: XM_040293963   ⟹   XP_040149897
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,680,707 - 59,936,861 (+)NCBI
RefSeq Acc Id: XM_040293964   ⟹   XP_040149898
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,817,223 - 59,936,861 (+)NCBI
RefSeq Acc Id: XM_040293965   ⟹   XP_040149899
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,680,997 - 59,940,562 (+)NCBI
RefSeq Acc Id: XM_040293966   ⟹   XP_040149900
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,680,997 - 59,936,821 (+)NCBI
RefSeq Acc Id: XM_040293967   ⟹   XP_040149901
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530359,888,018 - 59,940,562 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005323045   ⟸   XM_005322988
- Peptide Label: isoform X1
- UniProtKB: I3NAC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580599   ⟸   XM_021724924
- Peptide Label: isoform X1
- UniProtKB: I3NAC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040149897   ⟸   XM_040293963
- Peptide Label: isoform X1
- UniProtKB: I3NAC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040149899   ⟸   XM_040293965
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040149896   ⟸   XM_040293962
- Peptide Label: isoform X1
- UniProtKB: I3NAC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040149900   ⟸   XM_040293966
- Peptide Label: isoform X3
- UniProtKB: I3MJQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040149898   ⟸   XM_040293964
- Peptide Label: isoform X1
- UniProtKB: I3NAC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040149901   ⟸   XM_040293967
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000021326   ⟸   ENSSTOT00000023665
RefSeq Acc Id: ENSSTOP00000011417   ⟸   ENSSTOT00000012741
Protein Domains
bHLH   PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022157 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012741.3 UniProtKB/TrEMBL
  ENSSTOT00000023665.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  6.10.140.20 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  DUF4927 UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  NCO_DUF1518 UniProtKB/TrEMBL
  NCOA2 UniProtKB/TrEMBL
  Nuc_rcpt_coact UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa-typ UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa_int_sf UniProtKB/TrEMBL
  Nuclear_rcpt_coactivator UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  SRC/p160_LXXLL UniProtKB/TrEMBL
NCBI Gene Ncoa2 ENTREZGENE
PANTHER PTHR10684 UniProtKB/TrEMBL
  PTHR10684:SF2 UniProtKB/TrEMBL
Pfam DUF1518 UniProtKB/TrEMBL
  DUF4927 UniProtKB/TrEMBL
  NCOA_u2 UniProtKB/TrEMBL
  Nuc_rec_co-act UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
  SRC-1 UniProtKB/TrEMBL
PIRSF Nuclear_receptor_coactivator UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART DUF1518 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
  SSF69125 UniProtKB/TrEMBL
UniProt I3MJQ5 ENTREZGENE, UniProtKB/TrEMBL
  I3NAC9 ENTREZGENE, UniProtKB/TrEMBL