G6pd (glucose-6-phosphate dehydrogenase)

Gene: G6pd (glucose-6-phosphate dehydrogenase) Ictidomys tridecemlineatus

Analyze

Symbol:

G6pd

Name:

glucose-6-phosphate dehydrogenase

RGD ID:

12621823

Description:

ENCODES a protein that exhibits carbohydrate binding (ortholog); glucose binding (ortholog); glucose-6-phosphate dehydrogenase activity (ortholog); INVOLVED IN angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (ortholog); angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure (ortholog); erythrocyte development (ortholog); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH acquired angioedema (ortholog); acute kidney failure (ortholog); adrenoleukodystrophy (ortholog); FOUND IN cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase, transcript variant X1; glucose-6-phosphate dehydrogenase, transcript variant X2; glucose-6-phosphate dehydrogenase, transcript variant X3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,532,130 - 119,548,019 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	1,269,914 - 1,285,889 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	1,269,900 - 1,285,853 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acquired angioedema (ISO)

acute kidney failure (ISO)

adrenoleukodystrophy (ISO)

ALAD-Deficiency Porphyria (ISO)

anemia (ISO)

autistic disorder (ISO)

Barth syndrome (ISO)

Brain Injuries (ISO)

cataract (ISO)

cerebral creatine deficiency syndrome 1 (ISO)

cerebrovascular disease (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

chronic granulomatous disease (ISO)

congenital hemolytic anemia (ISO)

congenital hypothyroidism (ISO)

congenital nonspherocytic hemolytic anemia (ISO)

contact dermatitis (ISO)

diabetes mellitus (ISO)

Diabetic Nephropathies (ISO)

dyskeratosis congenita (ISO)

ectodermal dysplasia and immune deficiency (ISO)

ectodermal dysplasia and immunodeficiency 1 (ISO)

Emery-Dreifuss muscular dystrophy (ISO)

Experimental Diabetes Mellitus (ISO)

favism (ISO)

Fever (ISO)

genetic disease (ISO)

glucosephosphate dehydrogenase deficiency (ISO)

Hemolysis (ISO)

hemolytic anemia (ISO)

hepatic encephalopathy (ISO)

hepatocellular carcinoma (ISO)

Hypercholesterolemia (ISO)

hyperhomocysteinemia (ISO)

Hypertriglyceridemia (ISO)

immunodeficiency 14 (ISO)

immunodeficiency 33 (ISO)

Insulin Resistance (ISO)

kidney disease (ISO)

Liver Injury (ISO)

malaria (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Metabolic Syndrome (ISO)

Multi-Infarct Dementia (ISO)

myocardial infarction (ISO)

Neonatal Hyperbilirubinemia (ISO)

neonatal jaundice (ISO)

obesity (ISO)

paraplegia (ISO)

periventricular nodular heterotopia (ISO)

phagocyte bactericidal dysfunction (ISO)

phenylketonuria (ISO)

Plasmodium falciparum malaria (ISO)

Pulmonary Hypertension, Hypoxia-Induced (ISO)

renovascular hypertension (ISO)

Reperfusion Injury (ISO)

severe congenital encephalopathy due to MECP2 mutation (ISO)

Splenomegaly (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Testicular Injury (ISO)

transient cerebral ischemia (ISO)

type 1 diabetes mellitus (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (ISO)

angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure (ISO)

cellular response to oxidative stress (IEA)

cholesterol biosynthetic process (IEA)

erythrocyte development (ISO)

erythrocyte maturation (IEA)

glucose 6-phosphate metabolic process (IEA,ISO)

glucose metabolic process (IEA)

glutathione metabolic process (IEA,ISO)

NADP biosynthetic process (ISO)

NADP metabolic process (IEA)

NADPH regeneration (IEA)

negative regulation of cell growth involved in cardiac muscle cell development (ISO)

negative regulation of protein glutathionylation (IEA)

negative regulation of reactive oxygen species metabolic process (ISO)

pentose biosynthetic process (IEA,ISO)

pentose-phosphate shunt (IEA,ISO)

pentose-phosphate shunt, oxidative branch (IEA,ISO)

positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ISO)

regulation of multicellular organism growth (ISO)

regulation of neuron apoptotic process (ISO)

response to ethanol (ISO)

response to food (ISO)

response to iron(III) ion (ISO)

response to organic cyclic compound (ISO)

response to oxidative stress (ISO)

ribose phosphate biosynthetic process (IEA)

substantia nigra development (ISO)

Cellular Component

centriolar satellite (IEA)

cytoplasm (IEA)

cytoplasmic side of plasma membrane (IEA)

cytosol (IEA,ISO)

intracellular membrane-bounded organelle (IEA)

Molecular Function

carbohydrate binding (ISO)

glucose binding (IEA,ISO)

glucose-6-phosphate dehydrogenase activity (IEA,ISO)

identical protein binding (IEA)

NADP binding (IEA,ISO)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on CH-OH group of donors (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

pentose phosphate pathway (ISO)

pentose phosphate pathway - oxidative phase (ISO)

ribose 5-phosphate isomerase deficiency pathway (ISO)

transaldolase deficiency pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

G6pd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,532,130 - 119,548,019 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	1,269,914 - 1,285,889 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	1,269,900 - 1,285,853 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

G6PD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	154,531,390 - 154,547,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	154,517,825 - 154,547,572 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	153,759,605 - 153,775,784 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	153,412,800 - 153,428,981 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	153,323,309 - 153,339,173	NCBI
Celera	X	153,920,654 - 153,936,836 (-)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	142,336,102 - 142,352,295 (-)	NCBI		HuRef
CHM1_1	X	153,671,375 - 153,687,556 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	152,767,773 - 152,783,952 (-)	NCBI		T2T-CHM13v2.0

G6pdx
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	73,453,089 - 73,472,486 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	73,453,089 - 73,472,800 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	74,409,483 - 74,428,880 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	74,409,483 - 74,429,194 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	71,654,825 - 71,674,500 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	70,662,206 - 70,681,881 (-)	NCBI		MGSCv36	mm8
Celera	X	65,663,679 - 65,683,364 (-)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	38.0	NCBI

G6pd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	157,352,364 - 157,372,144 (-)	NCBI		GRCr8
mRatBN7.2	X	152,201,081 - 152,220,863 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	152,201,098 - 152,220,801 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	154,342,199 - 154,361,983 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,905,010 - 157,924,794 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	155,577,228 - 155,597,010 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	156,274,800 - 156,293,935 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	156,274,800 - 156,293,926 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	152,015,532 - 152,034,676 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	160,186,450 - 160,192,316 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	135,676,941 - 135,696,556 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

G6pd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	1,045,294 - 1,057,083 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955580	1,045,294 - 1,058,129 (-)	NCBI	ChiLan1.0	ChiLan1.0

G6PD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	154,505,413 - 154,521,575 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	154,509,020 - 154,525,182 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,972,798 - 143,988,960 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,843,092 - 153,860,675 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,843,092 - 153,860,674 (-)	Ensembl	panpan1.1		panPan2

G6PD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	122,217,317 - 122,231,862 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	122,205,683 - 122,231,678 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	125,358,989 - 125,373,645 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	125,346,698 - 125,373,679 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	121,127,964 - 121,142,608 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	123,643,041 - 123,657,679 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	123,404,813 - 123,419,460 (-)	NCBI		UU_Cfam_GSD_1.0

G6PD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,029,150 - 125,041,040 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	125,029,147 - 125,041,040 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	143,553,693 - 143,556,137 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

G6PD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	128,768,028 - 128,788,366 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	128,770,268 - 128,786,961 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	66,762,820 - 66,779,827 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

G6pd
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	986,107 - 1,001,955 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	989,376 - 1,001,787 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005340657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021720426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021720427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000025403 ⟹ ENSSTOP00000020461

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936809	1,269,914 - 1,285,889 (-)	Ensembl

RefSeq Acc Id:

XM_005340657 ⟹ XP_005340714

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	119,532,130 - 119,548,019 (-)	NCBI
SpeTri2.0	NW_004936809	1,269,901 - 1,285,853 (-)	NCBI

Sequence:

show sequence

CTGCCTGGGACTGCCCCGTGCCCATAAAGCATCCCGATCTCGTGCAGGGAGGACAGCGGGCGGA
TCAACCATCAGTGCAGAGAGCACCATGGCAGAGCAGGTAGCCCTGAGTCGGACCCAGGTGTGCG
GGATCCTGCGGGAAGAGCTGTACCAGGGTGATGCCTTCCACCAGGCTGATACACATATATTCAT
CATCATGGGTGCATCGGGCGACCTTGCCAAGAAGAAAATCTACCCCACCATCTGGTGGCTGTTC
CGTGATGGCCTTCTACCCGAAGACACCTTCATCGTGGGCTATGCTCGCTCCCGTCTCACAGTGG
ATGACATCCGTAAGCAGAGTGAGCCCTTCTTCAGAGCCACCCCAGAGGAGAGGCCCAAGCTGGA
GGAGTTCTTCACCCGCAATTCCTATGTGGCCGGCCAGTATGACGACCCAGCCTCCTTCAAGCGC
CTGAACAGCCATATGAACGCCCTTCACCAGGGGCCACAGGCCAACCGGCTTTTCTACCTGGCCT
TGCCTCCCACAGTTTATGAGGCTGTCACCAAGAACATCCATGAGACCTGCATGAGCCAGACAGG
CTGGAATCGCATTATTGTGGAGAAGCCCTTCGGGAGAGATCTACAGAGCTCTGACCAGCTGTCC
AACCACATCTCTTCCCTGTTCCGTGAGGACCAGATCTATCGCATTGACCACTACCTGGGCAAGG
AGATGGTTCAGAACCTCATGGTGCTGAGATTTGCCAACAGGATCTTTGGCCCCATCTGGAACCG
GGACAACATTGCCTGTGTGATCCTCACCTTCAAAGAGCCCTTTGGCACTGAGGGCCGTGGGGGC
TACTTTGATGAATTTGGGATTATCCGGGATGTGATGCAGAACCACCTTCTGCAGATGCTGTGTC
TGGTGGCCATGGAGAAGCCTGCCTCCACTGACTCAGATGATGTCCGTGATGAGAAGGTCAAGGT
ATTGAAATGTATCTCAGAGGTGCAGGCTGACAACGTGGTCCTGGGCCAGTACGTGGGGAACCCC
AGTGGAGAGGGTGAGGCCACCAAAGGGTACCTGGATGACCCCACAGTGCCCCATGGGTCCACCA
CTGCTACCTTTGCAGCTGTTGTCCTCTATGTGGAGAATGAGCGGTGGGATGGGGTGCCCTTCAT
CCTGCGCTGTGGCAAAGCCCTGAATGAGCGCAAGGCCGAGGTGAGGCTGCAGTTCCGCGATGTG
GCCGGTGACATCTTCCACCAGCAGTGTAAGCGCAATGAGCTGGTGATCCGAGTGCAGCCAAATG
AAGCCGTGTACACCAAGATGATGACCAAGAAGCCTGGCATGTTCTTCAACCCTGAGGAATCAGA
GCTGGACCTGACTTACGGCAACAGATACAAGAACGTGAAGCTTCCTGATGCCTATGAGCGCCTC
ATTCTGGACGTCTTCTGTGGGAGCCAGATGCACTTTGTGCGCAGCGATGAGCTCCGGGAGGCCT
GGCGGATCTTCACACCACTGCTGCACAGGATTGAGCGAGAGAAGCCCCAACCCATCCCTTACAC
ATATGGCAGCCGAGGCCCTGTGGAGGCAGATGAGCTGATGAAGAGAGTGGGCTTCCAGTATGAG
GGCACCTACAAGTGGGTGAACCCCCACAAGCTCTGAGACCCAGGCACCCACTCCCACCCTACCC
CATCTGCCCCCTGTGTTTGTCCTTCCCACCACCCGACCTCACCTCAGGAGAACCCCATGATGGG
AAGACTTCGGGACCATAGGCCTAACATTCCTCAGCCCCAGGCTTGGGCCACCACCATCTTTCCC
TTGCTGCTGATGCTACTGCTTTTGCTACCATTGTGACCGCCGCCGCCGCTAACATCAGTACCCC
TCCCTGGGCCCAGCTACATTCTTCAACCATTAAGCACCAATGACACGCATCATGACTGTCCTGA
GCCAGTGCCGGCCCTGTCTGAGCCACCAATCTCTCCATGGAACCTGAGTCACTTCCTCCCTTTA
CTCCAACCTCCAGAGAAGAAGAGTGGCCCATCAGTGTGTCCCAGGACTTCTCAGGACAAAATGT
TAGGGACAATGGGCCATAGTGGGGCAGTGGCCAAATCACACTCCCCAGTGGCTATGAGTAAGCT
CCTCTGAACTTGAGGAAGTGACCAAGTGCATCCATGTGAGATCCCATGGGCACACTAGCCTCAA
TGCCAGTTGACATTCCTGGTCACCAGGTAGAAGGGACCTCACGCTGCCCAGCAGGGTCTTGTTC
TCCCAGATGTCCCTTCTTAAGAATTCTGCACTCCGTGGAAAGGCAGAAGCAGCAGCTGAGAGTC
CCCTCAACCCCTGCCATTAAATCCTCAAACAGCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005340714	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020461.1
GenBank Protein	KAG3273254	(Get FASTA)	NCBI Sequence Viewer
	KAG3273255	(Get FASTA)	NCBI Sequence Viewer
	KAG3273256	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005340714 ⟸ XM_005340657

- UniProtKB:

I3N7W5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPED
TFIVGYARSRLTVDDIRKQSEPFFRATPEERPKLEEFFTRNSYVAGQYDDPASFKRLNSHMNAL
HQGPQANRLFYLALPPTVYEAVTKNIHETCMSQTGWNRIIVEKPFGRDLQSSDQLSNHISSLFR
EDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGII
RDVMQNHLLQMLCLVAMEKPASTDSDDVRDEKVKVLKCISEVQADNVVLGQYVGNPSGEGEATK
GYLDDPTVPHGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFHQQ
CKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGS
QMHFVRSDELREAWRIFTPLLHRIEREKPQPIPYTYGSRGPVEADELMKRVGFQYEGTYKWVNP
HKL

hide sequence

RefSeq Acc Id:

ENSSTOP00000020461 ⟸ ENSSTOT00000025403

Protein Domains

Glucose-6-phosphate dehydrogenase C-terminal Glucose-6-phosphate dehydrogenase NAD-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000021077	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000025403.2	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	G6P_DH	UniProtKB/TrEMBL
	G6P_DH_AS	UniProtKB/TrEMBL
	G6P_DH_C	UniProtKB/TrEMBL
	G6P_DH_NAD-bd	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
NCBI Gene	G6pd	ENTREZGENE
PANTHER	GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE	UniProtKB/TrEMBL
	PTHR23429	UniProtKB/TrEMBL
Pfam	G6PD_C	UniProtKB/TrEMBL
	G6PD_N	UniProtKB/TrEMBL
PIRSF	G6PD	UniProtKB/TrEMBL
PRINTS	G6PDHDRGNASE	UniProtKB/TrEMBL
PROSITE	G6P_DEHYDROGENASE	UniProtKB/TrEMBL
Superfamily-SCOP	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	I3N7W5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB