Gnaz (G protein subunit alpha z) - Rat Genome Database

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Gene: Gnaz (G protein subunit alpha z) Ictidomys tridecemlineatus
Analyze
Symbol: Gnaz
Name: G protein subunit alpha z
RGD ID: 12589738
Description: ENCODES a protein that exhibits G protein-coupled serotonin receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled serotonin receptor signaling pathway (ortholog); PARTICIPATES IN endothelin signaling pathway; Hedgehog signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH chromosome 22q11.2 deletion syndrome, distal (ortholog); DiGeorge syndrome (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G protein subunit alpha z, transcript variant X1; G protein subunit alpha z, transcript variant X2; G protein subunit alpha z, transcript variant X3; guanine nucleotide-binding protein G(z) subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619191,091 - 244,235 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619191,097 - 244,034 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gnaz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619191,091 - 244,235 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619191,097 - 244,034 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,070,519 - 23,125,032 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,070,519 - 23,125,032 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,412,705 - 23,467,219 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362221,742,669 - 21,797,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 342221,737,222 - 21,791,775NCBI
Celera227,227,239 - 7,281,792 (+)NCBICelera
Cytogenetic Map22q11.22-q11.23NCBI
HuRef226,380,502 - 6,434,961 (+)NCBIHuRef
CHM1_12223,424,953 - 23,479,508 (+)NCBICHM1_1
T2T-CHM13v2.02223,493,390 - 23,547,904 (+)NCBIT2T-CHM13v2.0
Gnaz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391074,803,009 - 74,852,739 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1074,803,009 - 74,852,739 (+)EnsemblGRCm39 Ensembl
GRCm381074,967,177 - 75,016,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1074,967,177 - 75,016,907 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,429,976 - 74,478,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361074,410,947 - 74,459,593 (+)NCBIMGSCv36mm8
Celera1076,015,010 - 76,063,654 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1038.48NCBI
Gnaz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,642,853 - 13,693,616 (-)NCBIGRCr8
mRatBN7.22013,643,473 - 13,694,240 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,644,640 - 13,669,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2014,351,133 - 14,376,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,711,964 - 13,737,230 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02014,184,561 - 14,209,827 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,593,072 - 14,644,020 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,593,819 - 14,620,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,776,281 - 16,801,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42014,148,003 - 14,174,136 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12014,147,070 - 14,198,741 (-)NCBI
Celera2015,127,777 - 15,153,073 (-)NCBICelera
Cytogenetic Map20p12NCBI
Gnaz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554557,501,153 - 7,554,235 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554557,501,153 - 7,554,235 (+)NCBIChiLan1.0ChiLan1.0
GNAZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22332,902,100 - 32,956,731 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12235,125,858 - 35,180,490 (-)NCBINHGRI_mPanPan1
PanPan1.12221,694,068 - 21,748,459 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2221,719,169 - 21,746,851 (+)Ensemblpanpan1.1panPan2
GNAZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12627,780,598 - 27,811,688 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2627,781,704 - 27,810,188 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2626,858,045 - 26,887,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,186,052 - 29,215,701 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,163,807 - 29,215,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12627,269,346 - 27,298,991 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02626,887,024 - 26,916,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02627,876,069 - 27,905,727 (+)NCBIUU_Cfam_GSD_1.0
GNAZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,132,013 - 49,174,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,132,012 - 49,174,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,573,000 - 52,597,219 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNAZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,758,097 - 2,812,306 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl192,757,819 - 2,788,076 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660854,314,170 - 4,368,661 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnaz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247479,425,775 - 9,480,162 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247479,425,720 - 9,479,571 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014032   ⟹   ENSSTOP00000012572
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936619191,091 - 244,235 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000041424   ⟹   ENSSTOP00000028943
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936619191,091 - 244,235 (+)Ensembl
RefSeq Acc Id: XM_005334443   ⟹   XP_005334500
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBI
SpeTri2.0NW_004936619191,097 - 244,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040289340   ⟹   XP_040145274
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBI
RefSeq Acc Id: XM_040289341   ⟹   XP_040145275
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBI
RefSeq Acc Id: XM_040289342   ⟹   XP_040145276
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,554,356 (-)NCBI
RefSeq Acc Id: XM_040289343   ⟹   XP_040145277
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBI
RefSeq Acc Id: XM_040289344   ⟹   XP_040145278
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118142,510,028 - 142,562,559 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005334500   ⟸   XM_005334443
- Peptide Label: isoform X2
- UniProtKB: I3MM56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040145274   ⟸   XM_040289340
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040145275   ⟸   XM_040289341
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040145277   ⟸   XM_040289343
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040145278   ⟸   XM_040289344
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040145276   ⟸   XM_040289342
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000028943   ⟸   ENSSTOT00000041424
RefSeq Acc Id: ENSSTOP00000012572   ⟸   ENSSTOT00000014032


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014033 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014032.3 UniProtKB/TrEMBL
  ENSSTOT00000041424.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.400.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Gprotein_alpha_I UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Gnaz ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA UniProtKB/TrEMBL
  PTHR10218 UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/TrEMBL
PRINTS GPROTEINA UniProtKB/TrEMBL
  GPROTEINAI UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/TrEMBL
SMART G_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt I3MM56 ENTREZGENE, UniProtKB/TrEMBL