Gnaz (guanine nucleotide binding protein, alpha z subunit) - Rat Genome Database

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Gene: Gnaz (guanine nucleotide binding protein, alpha z subunit) Mus musculus
Analyze
Symbol: Gnaz
Name: guanine nucleotide binding protein, alpha z subunit
RGD ID: 736020
MGI Page MGI
Description: Enables adenylate cyclase inhibitor activity. Involved in negative regulation of insulin secretion. Acts upstream of or within G protein-coupled serotonin receptor signaling pathway. Located in cell body and dendrite. Is active in plasma membrane. Is expressed in early conceptus; early tubule; gonad; and nervous system. Orthologous to human GNAZ (G protein subunit alpha z).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI847979; g(x) alpha chain; guanine nucleotide-binding protein G(z) subunit alpha; Gz; gz-alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391074,803,009 - 74,852,739 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1074,803,009 - 74,852,739 (+)EnsemblGRCm39 Ensembl
GRCm381074,967,177 - 75,016,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1074,967,177 - 75,016,907 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,429,976 - 74,478,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361074,410,947 - 74,459,593 (+)NCBIMGSCv36mm8
Celera1076,015,010 - 76,063,654 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1038.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP)
atrazine  (ISO)
benzene  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
Brodifacoum  (ISO)
CGP 52608  (ISO)
copper(II) sulfate  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diazinon  (ISO)
dichlorine  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
gentamycin  (ISO)
guanosine 5'-[gamma-thio]triphosphate  (EXP)
hydrogen peroxide  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
morphine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrofen  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sirolimus  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
testosterone  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vitamin E  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs. Yang J, etal., Proc Natl Acad Sci U S A 2000 Aug 29;97(18):9984-9.
Additional References at PubMed
PMID:1302014   PMID:2508088   PMID:3129724   PMID:3923359   PMID:8013366   PMID:8858601   PMID:8889548   PMID:9593921   PMID:9653653   PMID:10349636   PMID:10480904   PMID:10869496  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11307826   PMID:11685543   PMID:11950062   PMID:11970953   PMID:12008073   PMID:12198116   PMID:12297509   PMID:12414994   PMID:12466851  
PMID:12477932   PMID:15033343   PMID:15489334   PMID:15931062   PMID:16141072   PMID:16141073   PMID:16220329   PMID:16602821   PMID:16919471   PMID:17684732   PMID:18096703   PMID:18287559  
PMID:19284549   PMID:19446022   PMID:20152175   PMID:20946953   PMID:21220323   PMID:21267068   PMID:21873635   PMID:22457354   PMID:22794259   PMID:24076664   PMID:25535338   PMID:27160897  
PMID:28419211   PMID:28634551   PMID:28706196   PMID:29088301   PMID:29111324   PMID:30068389   PMID:30550785   PMID:32581705   PMID:33172888   PMID:36808153   PMID:38187761  


Genomics

Comparative Map Data
Gnaz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391074,803,009 - 74,852,739 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1074,803,009 - 74,852,739 (+)EnsemblGRCm39 Ensembl
GRCm381074,967,177 - 75,016,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1074,967,177 - 75,016,907 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,429,976 - 74,478,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361074,410,947 - 74,459,593 (+)NCBIMGSCv36mm8
Celera1076,015,010 - 76,063,654 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1038.48NCBI
GNAZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,070,519 - 23,125,032 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,070,519 - 23,125,032 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,412,705 - 23,467,219 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362221,742,669 - 21,797,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 342221,737,222 - 21,791,775NCBI
Celera227,227,239 - 7,281,792 (+)NCBICelera
Cytogenetic Map22q11.22-q11.23NCBI
HuRef226,380,502 - 6,434,961 (+)NCBIHuRef
CHM1_12223,424,953 - 23,479,508 (+)NCBICHM1_1
T2T-CHM13v2.02223,493,390 - 23,547,904 (+)NCBIT2T-CHM13v2.0
Gnaz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,642,853 - 13,693,616 (-)NCBIGRCr8
mRatBN7.22013,643,473 - 13,694,240 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,644,640 - 13,669,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2014,351,133 - 14,376,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,711,964 - 13,737,230 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02014,184,561 - 14,209,827 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,593,072 - 14,644,020 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,593,819 - 14,620,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,776,281 - 16,801,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42014,148,003 - 14,174,136 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12014,147,070 - 14,198,741 (-)NCBI
Celera2015,127,777 - 15,153,073 (-)NCBICelera
Cytogenetic Map20p12NCBI
Gnaz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554557,501,153 - 7,554,235 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554557,501,153 - 7,554,235 (+)NCBIChiLan1.0ChiLan1.0
GNAZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22332,902,100 - 32,956,731 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12235,125,858 - 35,180,490 (-)NCBINHGRI_mPanPan1
PanPan1.12221,694,068 - 21,748,459 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2221,719,169 - 21,746,851 (+)Ensemblpanpan1.1panPan2
GNAZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12627,780,598 - 27,811,688 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2627,781,704 - 27,810,188 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2626,858,045 - 26,887,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,186,052 - 29,215,701 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,163,807 - 29,215,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12627,269,346 - 27,298,991 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02626,887,024 - 26,916,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02627,876,069 - 27,905,727 (+)NCBIUU_Cfam_GSD_1.0
Gnaz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118142,510,028 - 142,562,971 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619191,091 - 244,235 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619191,097 - 244,034 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,132,013 - 49,174,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,132,012 - 49,174,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,573,000 - 52,597,219 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNAZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,758,097 - 2,812,306 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl192,757,819 - 2,788,076 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660854,314,170 - 4,368,661 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnaz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247479,425,775 - 9,480,162 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247479,425,720 - 9,479,571 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gnaz
1457 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1253
Count of miRNA genes:429
Interacting mature miRNAs:503
Transcripts:ENSMUST00000037813, ENSMUST00000159991, ENSMUST00000160421
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse

Markers in Region
AI847979  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381075,016,569 - 75,016,711UniSTSGRCm38
MGSCv371074,479,314 - 74,479,456UniSTSGRCm37
Celera1076,064,346 - 76,064,488UniSTS
Cytogenetic Map10B5.3UniSTS
Whitehead/MRC_RH10855.68UniSTS
Gnaz  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371074,454,691 - 74,454,837UniSTSGRCm37
Celera1076,039,722 - 76,039,868UniSTS
Cytogenetic Map10B5.3UniSTS
cM Map1040.5UniSTS
Gnaz  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B5.3UniSTS
cM Map1040.5UniSTS
GNAZ  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381074,991,946 - 74,992,092UniSTSGRCm38
MGSCv371074,454,691 - 74,454,837UniSTSGRCm37
Celera1076,039,722 - 76,039,868UniSTS
Cytogenetic Map10B5.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC003059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC142500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF056972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF056973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF456902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG089218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY128192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY291477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY718552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD776772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX734056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L17074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000037813   ⟹   ENSMUSP00000036087
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1074,803,009 - 74,852,739 (+)Ensembl
GRCm38.p6 Ensembl1074,967,177 - 75,016,907 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159991   ⟹   ENSMUSP00000124639
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1074,826,673 - 74,852,730 (+)Ensembl
GRCm38.p6 Ensembl1074,990,841 - 75,016,898 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1074,803,041 - 74,827,236 (+)Ensembl
GRCm38.p6 Ensembl1074,967,209 - 74,991,404 (+)Ensembl
RefSeq Acc Id: NM_001358848   ⟹   NP_001345777
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391074,803,063 - 74,852,739 (+)NCBI
GRCm381074,967,231 - 75,016,907 (+)NCBI
Sequence:
RefSeq Acc Id: NM_010311   ⟹   NP_034441
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391074,803,009 - 74,852,739 (+)NCBI
GRCm381074,967,177 - 75,016,907 (+)NCBI
MGSCv371074,429,976 - 74,478,622 (+)RGD
Celera1076,015,010 - 76,063,654 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513235   ⟹   XP_006513298
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391074,803,216 - 74,852,739 (+)NCBI
GRCm381074,967,423 - 75,016,907 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006513236   ⟹   XP_006513299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391074,808,032 - 74,852,739 (+)NCBI
GRCm381074,972,225 - 75,016,907 (+)NCBI
Sequence:
RefSeq Acc Id: NP_034441   ⟸   NM_010311
- UniProtKB: Q61637 (UniProtKB/Swiss-Prot),   O70442 (UniProtKB/Swiss-Prot),   Q91WM4 (UniProtKB/Swiss-Prot),   O70443 (UniProtKB/Swiss-Prot),   Q542R8 (UniProtKB/TrEMBL),   Q3UYF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513298   ⟸   XM_006513235
- Peptide Label: isoform X1
- UniProtKB: Q61637 (UniProtKB/Swiss-Prot),   O70442 (UniProtKB/Swiss-Prot),   Q91WM4 (UniProtKB/Swiss-Prot),   O70443 (UniProtKB/Swiss-Prot),   Q542R8 (UniProtKB/TrEMBL),   Q3UYF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513299   ⟸   XM_006513236
- Peptide Label: isoform X1
- UniProtKB: Q61637 (UniProtKB/Swiss-Prot),   O70442 (UniProtKB/Swiss-Prot),   Q91WM4 (UniProtKB/Swiss-Prot),   O70443 (UniProtKB/Swiss-Prot),   Q542R8 (UniProtKB/TrEMBL),   Q3UYF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345777   ⟸   NM_001358848
- UniProtKB: Q61637 (UniProtKB/Swiss-Prot),   O70443 (UniProtKB/Swiss-Prot),   O70442 (UniProtKB/Swiss-Prot),   Q91WM4 (UniProtKB/Swiss-Prot),   Q542R8 (UniProtKB/TrEMBL),   Q3UYF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000124639   ⟸   ENSMUST00000159991
RefSeq Acc Id: ENSMUSP00000036087   ⟸   ENSMUST00000037813
Protein Domains
G-alpha

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70443-F1-model_v2 AlphaFold O70443 1-355 view protein structure

Promoters
RGD ID:6819387
Promoter ID:MM_KWN:4530
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000082314,   OTTMUST00000082316
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361074,429,569 - 74,430,069 (+)MPROMDB
RGD ID:8672286
Promoter ID:EPDNEW_M14173
Type:initiation region
Name:Gnaz_1
Description:Mus musculus guanine nucleotide binding protein, alpha z subunit, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381074,967,146 - 74,967,206EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95780 AgrOrtholog
Ensembl Genes ENSMUSG00000040009 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037813 ENTREZGENE
  ENSMUST00000037813.5 UniProtKB/Swiss-Prot
  ENSMUST00000159991 ENTREZGENE
  ENSMUST00000159991.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Gprotein_alpha_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14687 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95780 ENTREZGENE
NCBI Gene 14687 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gnaz PhenoGen
PRINTS GPROTEINA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPROTEINAI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART G_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GNAZ_MOUSE UniProtKB/Swiss-Prot
  O70442 ENTREZGENE
  O70443 ENTREZGENE
  Q3UYF9 ENTREZGENE, UniProtKB/TrEMBL
  Q542R8 ENTREZGENE, UniProtKB/TrEMBL
  Q61637 ENTREZGENE
  Q91WM4 ENTREZGENE
UniProt Secondary O70442 UniProtKB/Swiss-Prot
  Q61637 UniProtKB/Swiss-Prot
  Q91WM4 UniProtKB/Swiss-Prot