| 620711 | Dhh | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (ortholog); patched binding (ortholog); zinc ion binding (ortholog); INVOLVED IN multicellular organism development; myelination; response to estradiol; PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; ASSOCIATED WITH abnormal adult Leydig cell differentiation; abnormal fetal Leydig cell differentiation; decreased circulating testosterone level; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3-bis(4-hydroxyphenyl)propionitrile | 7 | 131929857 | 131935352 | Rat | 136 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1345874 | DHH | desert hedgehog signaling molecule | This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the s ignalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010] | 12 | 49086656 | 49094801 | Human | 178 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552726 | Dhh | desert hedgehog | Enables patched binding activity. Involved in several processes, including Schwann cell development; male gonad development; and paracrine signaling. Acts upstream of or within several processes, including Leydig cell differentiation; male sex determination; and osteoblast differentiation. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; heart and pericardium; and yolk sac. Used to study 46,XY complete gonadal dysgenesis. Human ortholog(s) of this gene implicated in 46,XY complete gonadal dysgenesis; 46,XY gonadal dysgenesis with minifascicular neuropathy; and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 98779496 | 98796443 | Mouse | 164 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 11754860 | DHH | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); extracellular region (inferred) | 12 | 39656046 | 39661439 | Bonobo | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12378936 | DHH | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); extracellular region (inferred) | 27 | 5490122 | 5497144 | Dog | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12580134 | Dhh | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); extracellular region (inferred) | NW_004936512 | 6885607 | 6889955 | Squirrel | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14191849 | DHH | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); extracellular region (inferred) | | | | Pig | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18754959 | DHH | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); extracellular space (inferred); plasma membrane (inferred) | | | | Green Monkey | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929713 | Dhh | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signalin g pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); extracellular region (inferred) | | | | Naked Mole-Rat | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866214 | DHH | desert hedgehog signaling molecule | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155234381 | dhh | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625940080 | Dhh | desert hedgehog signaling molecule | ENCODES a protein that exhibits calcium ion binding (ortholog); patched binding (ortholog); zinc ion binding (ortholog); INVOLVED IN Leydig cell differentiation (ortholog); male sex determination (ortholog); multicellular organism development (ortholog); PARTICIPATES IN altered Hedgehog signaling pa thway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY complete gonadal dysgenesis (ortholog); 46,XY gonadal dysgenesis with minifascicular neuropathy (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234382 | dhh.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245512 | dhh.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38673058 | DHH-AS1 | DHH antisense RNA 1 | | 12 | 49092080 | 49095744 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, MODEL [RefSeq] |
| 8963814 | LOC102028877 | desert hedgehog protein | | NW_004955500 | 7916583 | 7920075 | Chinchilla | | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16561284 | AC011603.1 | novel transcript, antisense to DHH | | | | | Human | | name | gene, lncrna |
| 14376051 | DHH1 | | | | | | Yeast | | symbol | gene, null |
| 14372428 | dhhc-1 | | | | | | Roundworm | | symbol | gene, null |
| 14376399 | dhhc-2 | | | | | | Roundworm | | symbol | gene, null |
| 14382908 | dhhc-3 | | | | | | Roundworm | | symbol | gene, null |
| 14373665 | dhhc-4 | | | | | | Roundworm | | symbol | gene, null |
| 25825600 | dhhc-5 | | | | | | Roundworm | | symbol | gene, null |
| 14381454 | dhhc-6 | | | | | | Roundworm | | symbol | gene, null |
| 14382910 | dhhc-7 | | | | | | Roundworm | | symbol | gene, null |
| 14376400 | dhhc-8 | | | | | | Roundworm | | symbol | gene, null |
| 14382912 | dhhc-9 | | | | | | Roundworm | | symbol | gene, null |
| 1313262 | Zdhhc1 | zinc finger, DHHC domain containing 1 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of protein-containing complex assembly. Acts upstream of or within protein palmitoylation. Located in end osome membrane. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; heart; and lung. Orthologous to human ZDHHC1 (zinc finger DHHC-type containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 106199055 | 106223694 | Mouse | 84 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1348828 | ZDHHC1 | zDHHC palmitoyltransferase 1 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; protein palmitoylation; and regulation of defense response. Located in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 67394152 | 67416477 | Human | 79 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1589775 | Zdhhc1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (o rtholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 19 | 50260445 | 50285634 | Rat | 72 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 9022635 | Zdhhc1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (o rtholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endosome membrane (ortholog) | NW_004955484 | 9224559 | 9245894 | Chinchilla | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11692234 | ZDHHC1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum m embrane (ortholog) | 16 | 47739857 | 47761887 | Bonobo | 24 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12269222 | ZDHHC1 | zinc finger DHHC-type containing 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum ( ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog) | 5 | 81985974 | 82006877 | Dog | 26 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12589690 | Zdhhc1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum m embrane (ortholog) | NW_004936475 | 17849772 | 17869140 | Squirrel | 24 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13859017 | ZDHHC1 | zinc finger DHHC-type containing 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum ( ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog) | | | | Pig | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18761873 | ZDHHC1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum m embrane (ortholog) | | | | Green Monkey | 24 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18932450 | Zdhhc1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN antiviral innate immune response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endosome membrane (ortholog) | | | | Naked Mole-Rat | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626085426 | Zdhhc1 | zDHHC palmitoyltransferase 1 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (o rtholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endosome membrane (ortholog) | | | | Black Rat | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 628681 | Zdhhc2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-myristoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation; positive regulation of AMPA glutamate receptor clustering; positive r egulation of endosome to plasma membrane protein transport; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse; postsynaptic density; endoplasmic reticulum (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 58511931 | 58581530 | Rat | 198 | symbol , old_gene_name , PhenoGen , name , ensembl_full_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 736613 | ZDHHC2 | zDHHC palmitoyltransferase 2 | Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; protein localization to membrane raft; and synapse assembly. Located in Golgi apparatus; endoplasmic reticulum membrane; and plasma membrane. Is active in postsynaptic recycling endosome. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 17156482 | 17224799 | Human | 170 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736614 | Zdhhc2 | zinc finger, DHHC domain containing 2 | Enables protein-cysteine S-myristoyltransferase activity; protein-cysteine S-palmitoyltransferase activity; and protein-cysteine S-stearoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation; protein localization to membrane; and synapse assembly. Acts upstream of or within postsy naptic neurotransmitter receptor cycle and protein palmitoylation. Located in plasma membrane; postsynaptic recycling endosome; and recycling endosome membrane. Is expressed in several structures, including early conceptus; genitourinary system; nervous system; pancreas tip epithelium; and retina. Orthologous to human ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 40876526 | 40946178 | Mouse | 208 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8734951 | Zdhhc2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-myristoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive regulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); glutamatergic synapse (ortholog) | NW_004955463 | 315531 | 345712 | Chinchilla | 44 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11994027 | ZDHHC2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive reg ulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog) | 8 | 16368954 | 16437623 | Bonobo | 43 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12421499 | ZDHHC2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein-cysteine S-myristoyltransferase activity (ortholog); protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate re ceptor clustering (ortholog); positive regulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); glutamatergic synapse (ortholog) | 16 | 40496469 | 40551979 | Dog | 49 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12678289 | Zdhhc2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive reg ulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog) | NW_004936573 | 6216084 | 6280142 | Squirrel | 43 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14199785 | ZDHHC2 | zinc finger DHHC-type palmitoyltransferase 2 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive reg ulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog); INTERACTS WITH deoxynivalenol; resveratrol | | | | Pig | 51 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18400717 | ZDHHC2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive reg ulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog) | | | | Green Monkey | 43 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18902859 | Zdhhc2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive reg ulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog) | | | | Naked Mole-Rat | 43 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625877899 | Zdhhc2 | zDHHC palmitoyltransferase 2 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-myristoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of AMPA glutamate receptor clustering (ortholog); positive regulation of endosome to plasma membrane protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Neoplasms (ortholog); Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); glutamatergic synapse (ortholog) | | | | Black Rat | 44 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1309041 | Zdhhc3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN lipoprotein localization to membrane (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of receptor localization to synapse (ortholog); FOUND IN Golgi apparatus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; aflatoxin B1 | 8 | 131602663 | 131650998 | Rat | 104 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1319160 | ZDHHC3 | zDHHC palmitoyltransferase 3 | Enables palmitoyltransferase activity. Involved in several processes, including protein localization to membrane; protein localization to photoreceptor outer segment; and regulation of signal transduction. Located in membrane. Is active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 44915261 | 44976174 | Human | 105 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1319161 | Zdhhc3 | zinc finger, DHHC domain containing 3 | Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation of GABAergic synaptic transmission; and positive regulation of receptor localization to synapse. Acts ups tream of or within protein targeting. Located in Golgi apparatus. Is expressed in central nervous system; early conceptus; genitourinary system; and ileum. Orthologous to human ZDHHC3 (zinc finger DHHC-type palmitoyltransferase 3). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 122895224 | 122942269 | Mouse | 128 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8991509 | Zdhhc3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN lipoprotein localization to membrane (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of receptor localization to synapse (ortholog); FOUND IN Golgi apparatus (ortholog) | NW_004955420 | 26698168 | 26736364 | Chinchilla | 25 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11865173 | ZDHHC3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); protein targeting (ortholog); FOUND IN Golgi ap paratus (ortholog) | 3 | 44816359 | 44877318 | Bonobo | 27 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12235298 | ZDHHC3 | zinc finger DHHC-type palmitoyltransferase 3 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); protein targeting (ortholog); FOUND IN Golgi ap paratus (inferred); membrane (inferred); INTERACTS WITH bisphenol A | 20 | 43379669 | 43433101 | Dog | 32 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12698114 | Zdhhc3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); protein targeting (ortholog); FOUND IN Golgi ap paratus (ortholog) | NW_004936695 | 776822 | 830693 | Squirrel | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13953823 | ZDHHC3 | zinc finger DHHC-type palmitoyltransferase 3 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); protein targeting (ortholog); FOUND IN Golgi ap paratus (inferred); membrane (inferred) | | | | Pig | 32 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18565948 | ZDHHC3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein homodimerization activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); protein targeting (ortholog); FOUND IN Golgi ap paratus (ortholog) | | | | Green Monkey | 27 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18899771 | Zdhhc3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN lipoprotein localization to membrane (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of receptor localization to synapse (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Naked Mole-Rat | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626016305 | Zdhhc3 | zDHHC palmitoyltransferase 3 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein homodimerization activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN lipoprotein localization to membrane (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of receptor localization to synapse (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Black Rat | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1308389 | Zdhhc4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); protein localization to plasma membrane (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrotoluene; bisphenol A | 12 | 16344447 | 16358493 | Rat | 62 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1318128 | ZDHHC4 | zDHHC palmitoyltransferase 4 | Enables palmitoyltransferase activity. Involved in positive regulation of innate immune response and protein localization to plasma membrane. Located in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 6577454 | 6589374 | Human | 55 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1318129 | Zdhhc4 | zinc finger, DHHC domain containing 4 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in positive regulation of innate immune response; protein localization to plasma membrane; and protein targeting to membrane. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; inner cell mass; oocyte; and pancreas tip epithelium. Orthologous to human ZDHHC4 (zinc finger DHHC-type palmitoyltransferase 4). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 143302244 | 143315007 | Mouse | 72 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9060955 | Zdhhc4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); protein localization to plasma membrane (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | NW_004955460 | 13119672 | 13133688 | Chinchilla | 6 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11985719 | ZDHHC4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); protei n targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | 7 | 6855657 | 6867537 | Bonobo | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12237559 | ZDHHC4 | zinc finger DHHC-type palmitoyltransferase 4 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | 6 | 11893007 | 11911657 | Dog | 18 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12544857 | Zdhhc4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); protei n targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | NW_004936765 | 101152 | 111249 | Squirrel | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13909998 | ZDHHC4 | zDHHC palmitoyltransferase 4 | ENCODES an ncrna that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); FOUND I N endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Pig | 18 | symbol , old_gene_name , name , ensembl_full_name | gene, ncrna, MODEL [RefSeq] |
| 18347740 | ZDHHC4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); protei n targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Green Monkey | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18930334 | Zdhhc4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of innate immune response (inferred); protein localization to plasma membrane (inferred); protei n targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Naked Mole-Rat | 18 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626139473 | Zdhhc4 | zDHHC palmitoyltransferase 4 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); protein localization to plasma membrane (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1314627 | ZDHHC5 | zDHHC palmitoyltransferase 5 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in positive regulation of defense response; positive regulation of protein localization to plasma membrane; and protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in nucleoplasm; phago cytic vesicle; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 57668114 | 57701182 | Human | 106 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1314628 | Zdhhc5 | zinc finger, DHHC domain containing 5 | Enables palmitoyltransferase activity. Involved in positive regulation of defense response and positive regulation of protein localization. Acts upstream of or within non-canonical inflammasome complex assembly; protein maturation; and protein palmitoylation. Located in dendrite; phagocytic vesicle; and plasma membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in early conceptus; eye; heart; oocyte; and trunk somite. Orthologous to human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 84518264 | 84545508 | Mouse | 148 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1589737 | Zdhhc5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN regulation of postsynaptic membrane neurotransmitter receptor levels; positive regulation of NLRP3 inflammasome complex assembly (ortholog); positive reg ulation of pattern recognition receptor signaling pathway (ortholog); FOUND IN dendrite; GABA-ergic synapse; glutamatergic synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 3 | 90178734 | 90206889 | Rat | 130 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9000586 | Zdhhc5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of NLRP3 inflammasome complex assembly (ortholog); positive regulation of pattern recognition receptor signaling pathway (ortholog); positive regulation of protein localization to phagocytic vesicle (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog) | NW_004955511 | 2597353 | 2625139 | Chinchilla | 31 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11929347 | ZDHHC5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); postsynaptic specialization, intracellular component (ortholog) | 11 | 52908693 | 52942028 | Bonobo | 33 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12394697 | ZDHHC5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits beta-catenin binding (ortholog); cell adhesion molecule binding (ortholog); cell-cell adhesion mediator activity (ortholog); INVOLVED IN cell adhesion (ortholog); cell migration involved in sprouting angiogenesis (ortholog); cell-cell adhesion (ortholog); ASSOCIATED W ITH pulmonary hypertension (ortholog); Right Ventricular Hypertrophy (ortholog); FOUND IN adherens junction (ortholog); apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog) | 18 | 38497649 | 38522728 | Dog | 92 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12701723 | Zdhhc5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); postsynaptic specialization, intracellular component (ortholog) | NW_004936581 | 4839511 | 4865406 | Squirrel | 33 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14003265 | ZDHHC5 | zinc finger DHHC-type palmitoyltransferase 5 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); postsynaptic specialization, intracellular component (ortholog) | | | | Pig | 33 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18661672 | ZDHHC5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); postsynaptic specialization, intracellular component (ortholog) | | | | Green Monkey | 33 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18913860 | Zdhhc5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of NLRP3 inflammasome complex assembly (ortholog); positive regulation of pattern recognition re ceptor signaling pathway (ortholog); positive regulation of protein localization to phagocytic vesicle (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog) | | | | Naked Mole-Rat | 35 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625940238 | Zdhhc5 | zDHHC palmitoyltransferase 5 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of NLRP3 inflammasome complex assembly (ortholog); positive regulation of pattern recognition receptor signaling pathway (ortholog); positive regulation of protein localization to phagocytic vesicle (ortholog); FOUND IN dendrite (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog) | | | | Black Rat | 31 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1304657 | Zdhhc6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2-amino-4,6-din itrotoluene; bisphenol A; cadmium atom | 1 | 264340883 | 264361435 | Rat | 63 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312223 | ZDHHC6 | zDHHC palmitoyltransferase 6 | Enables palmitoyltransferase activity and protein-cysteine S-stearoyltransferase activity. Involved in positive regulation of mitochondrial fusion; protein palmitoylation; and protein stearoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 10 | 112424412 | 112447572 | Human | 67 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551983 | Zdhhc6 | zinc finger, DHHC domain containing 6 | Predicted to enable protein-cysteine S-palmitoyltransferase activity and protein-cysteine S-stearoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed i n several structures, including eye; genitourinary system; heart; lung epithelium; and trunk somite. Orthologous to human ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 55286648 | 55304468 | Mouse | 69 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8965756 | Zdhhc6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | NW_004955431 | 17525752 | 17542540 | Chinchilla | 10 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11830930 | ZDHHC6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | 10 | 109021160 | 109038445 | Bonobo | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12087693 | ZDHHC6 | zinc finger DHHC-type palmitoyltransferase 6 | ENCODES a protein that exhibits protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | 28 | 23479978 | 23494977 | Dog | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12667043 | Zdhhc6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | NW_004936486 | 2993519 | 3010101 | Squirrel | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14128500 | ZDHHC6 | zinc finger DHHC-type palmitoyltransferase 6 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | | | | Pig | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18529495 | ZDHHC6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18904463 | Zdhhc6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | | | | Naked Mole-Rat | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625862291 | Zdhhc6 | zDHHC palmitoyltransferase 6 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-stearoyltransferase activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | | | | Black Rat | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 620205 | Zdhhc7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); glucose import in response to insulin stimulus (ortholog); negative regulation of catabolic process (orth olog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 19 | 65048140 | 65065286 | Rat | 123 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1332314 | Zdhhc7 | zinc finger, DHHC domain containing 7 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in glucose import in response to insulin stimulus; peptidyl-L-cysteine S-palmitoylation; and regulation of protein localization to plasma membrane. Located in Golgi apparatus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZDHHC7 (zinc finger DHHC-type palmitoyltransferase 7). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 120807834 | 120828211 | Mouse | 152 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1351877 | ZDHHC7 | zDHHC palmitoyltransferase 7 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including nuclear receptor-mediated steroid hormone signaling pathway; regulation of protein localization; and regulation of signal transduction. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 84974175 | 85027631 | Human | 100 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8893117 | Zdhhc7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); glucose import in response to insulin stimulus (ortholog); negative regulation of catabolic process (orth olog); FOUND IN Golgi apparatus (ortholog) | NW_004955541 | 398364 | 426330 | Chinchilla | 28 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11843928 | ZDHHC7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum ( inferred); Golgi apparatus (inferred); membrane (inferred) | 16 | 65643906 | 65681301 | Bonobo | 34 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12311931 | ZDHHC7 | zinc finger DHHC-type palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi apparatus (inferr ed); membrane (inferred) | 5 | 67554310 | 67580042 | Dog | 35 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12566217 | Zdhhc7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi apparatus (inferr ed); membrane (inferred) | NW_004936641 | 3175338 | 3199487 | Squirrel | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13998048 | ZDHHC7 | zinc finger DHHC-type palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi apparatus (inferr ed); membrane (inferred) | | | | Pig | 35 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18478962 | ZDHHC7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi apparatus (inferr ed); membrane (inferred) | | | | Green Monkey | 30 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18934896 | Zdhhc7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum ( inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Naked Mole-Rat | 34 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626000922 | Zdhhc7 | zDHHC palmitoyltransferase 7 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); glucose import in response to insulin stimulus (ortholog); negative regulation of catabolic process (orth olog); FOUND IN Golgi apparatus (ortholog) | | | | Black Rat | 28 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1308875 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ort holog); Golgi apparatus (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 11 | 96259383 | 96273588 | Rat | 64 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1318899 | ZDHHC8 | zDHHC palmitoyltransferase 8 | This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. A lternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010] | 22 | 20131804 | 20148007 | Human | 71 | symbol , old_gene_name , COSMIC , name , description , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1557928 | Zdhhc8 | zinc finger, DHHC domain containing 8 | Predicted to enable palmitoyltransferase activity. Involved in regulation of postsynapse assembly. Acts upstream of or within locomotory behavior. Located in mitochondrion. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including brain; cardiovascular system; forelimb bud; ganglia; and nose. Orthologous to human ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 18038612 | 18056471 | Mouse | 80 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8947755 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ort holog); Golgi apparatus (ortholog); mitochondrion (ortholog) | NW_004955442 | 17965186 | 17980854 | Chinchilla | 13 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12413789 | ZDHHC8 | zinc finger DHHC-type palmitoyltransferase 8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (inferred); Golgi apparatus (inferred); Golgi membrane (inferred) | 26 | 29192867 | 29208105 | Dog | 25 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12522503 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH prostate cancer (or tholog); FOUND IN glutamatergic synapse (inferred); Golgi apparatus (inferred); Golgi membrane (inferred) | NW_004936619 | 4032665 | 4048079 | Squirrel | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14079086 | ZDHHC8 | zinc finger DHHC-type palmitoyltransferase 8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH prostate cancer (or tholog); FOUND IN glutamatergic synapse (inferred); Golgi apparatus (inferred); Golgi membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 25 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18339437 | ZDHHC8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH prostate cancer (or tholog); FOUND IN glutamatergic synapse (inferred); Golgi apparatus (inferred); Golgi membrane (inferred) | | | | Green Monkey | 23 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18910022 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ortholog); mitochondrion (ortholog); postsynapse (ortholog) | | | | Naked Mole-Rat | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 32726657 | ZDHHC8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN Golgi apparatus (ortholog) | 22 | 2891738 | 2894404 | Bonobo | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625901169 | Zdhhc8 | zDHHC palmitoyltransferase 8 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN locomotory behavior (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN glutamatergic synapse (ort holog); Golgi apparatus (ortholog); mitochondrion (ortholog) | | | | Black Rat | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1348132 | ZDHHC9 | zDHHC palmitoyltransferase 9 | This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palm itoylates HRAS and NRAS. Mutations in this gene are associated with X-linked cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010] | X | 129803288 | 129843886 | Human | 172 | symbol , old_gene_name , COSMIC , name , description , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1556934 | Zdhhc9 | zinc finger, DHHC domain containing 9 | Predicted to enable Ras palmitoyltransferase activity. Involved in positive regulation of pyroptotic inflammatory response. Acts upstream of or within non-canonical inflammasome complex assembly and protein maturation. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of pa lmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study syndromic X-linked intellectual disability Raymond type. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). [provided by Alliance of Genome Resources, Apr 2025] | X | 47260844 | 47297792 | Mouse | 136 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1561389 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A | X | 132230243 | 132266139 | Rat | 105 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8930089 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog) | NW_004955473 | 5174575 | 5208767 | Chinchilla | 21 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11685150 | ZDHHC9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic diseas e (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | X | 118932986 | 118973238 | Bonobo | 32 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12378763 | ZDHHC9 | zinc finger DHHC-type palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic diseas e (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | X | 101011072 | 101096394 | Dog | 31 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12734336 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic diseas e (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | NW_004936479 | 1711756 | 1743306 | Squirrel | 32 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13996158 | ZDHHC9 | zinc finger DHHC-type palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic diseas e (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Pig | 31 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18414103 | ZDHHC9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog) | | | | Green Monkey | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18926212 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic diseas e (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Naked Mole-Rat | 32 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20866446 | ZDHHC9 | zinc finger DHHC-type palmitoyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN host-mediated activation of viral process (inferred); positive regulation of cGAS/STING signaling pathway (inferred) ; positive regulation of pyroptotic inflammatory response (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | | | | Green Monkey | 24 | symbol , old_gene_name , name | gene, protein-coding |
| 625839463 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14382906 | dhhc-10 | | | | | | Roundworm | | symbol | gene, null |
| 14374305 | dhhc-11 | | | | | | Roundworm | | symbol | gene, null |
| 14382907 | dhhc-12 | | | | | | Roundworm | | symbol | gene, null |
| 14375275 | dhhc-13 | | | | | | Roundworm | | symbol | gene, null |
| 14375276 | dhhc-14 | | | | | | Roundworm | | symbol | gene, null |
| 1343630 | ZDHHC11 | zDHHC palmitoyltransferase 11 | Enables signaling adaptor activity. Involved in antiviral innate immune response and positive regulation of defense response to virus by host. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 795605 | 860563 | Human | 70 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1564281 | Zdhhc11 | zDHHC palmitoyltransferase 11 | ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); positive regulation of defense response to virus by host (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH bisphenol A; DDT; trichloroethene | 1 | 31124900 | 31156075 | Rat | 64 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1616743 | Zdhhc11 | zinc finger, DHHC domain containing 11 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Located in endosome membrane. Is expressed in brain; male reproductive gland or organ; metanephr os; and submandibular gland. Orthologous to human ZDHHC11 (zinc finger DHHC-type containing 11) and ZDHHC11B (zinc finger DHHC-type containing 11B). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 74111970 | 74141109 | Mouse | 30 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12341040 | ZDHHC11 | zinc finger DHHC-type containing 11 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN antiviral innate immune response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endosome membrane (ortholog) | 34 | 11567784 | 11614975 | Dog | 11 | symbol , old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14070131 | ZDHHC11 | zinc finger DHHC-type containing 11 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of defense response to virus by host (ortholog) ; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endosome membrane (ortholog) | | | | Pig | 16 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 1306593 | Zdhhc12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN gephyrin clustering involved in postsynaptic density assembly (ortholog); negative regulation of NLRP3 inflammasome complex assembly (ortholog); peptidyl -L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 3 | 33761338 | 33764207 | Rat | 77 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315298 | ZDHHC12 | zDHHC palmitoyltransferase 12 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in gephyrin clustering involved in postsynaptic density assembly; negative regulation of NLRP3 inflammasome complex assembly; and protein palmitoylation. Located in Golgi apparatus and endoplasmic reticulum. Is active in dendritic sp ine. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 128720873 | 128724127 | Human | 70 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1315299 | Zdhhc12 | zinc finger, DHHC domain containing 12 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in gephyrin clustering involved in postsynaptic density assembly; peptidyl-L-cysteine S-palmitoylation; and positive regulation of GABAergic synaptic transmission. Located in Golgi apparatus. Is expressed in early conceptus; inner ce ll mass; and oocyte. Orthologous to human ZDHHC12 (zinc finger DHHC-type palmitoyltransferase 12). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 29980956 | 29983647 | Mouse | 79 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8966432 | Zdhhc12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN gephyrin clustering involved in postsynaptic density assembly (ortholog); negative regulation of NLRP3 inflammasome complex assembly (ortholog); peptidyl -L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | NW_004955570 | 1131234 | 1133909 | Chinchilla | 13 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11825751 | ZDHHC12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | 9 | 99844535 | 99847806 | Bonobo | 21 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12232962 | ZDHHC12 | zinc finger DHHC-type palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | 9 | 54877188 | 54880579 | Dog | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12493624 | Zdhhc12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | NW_004936487 | 16201288 | 16203818 | Squirrel | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14037437 | ZDHHC12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | | | | Pig | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18344274 | ZDHHC12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | | | | Green Monkey | 21 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18921397 | Zdhhc12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (inferred); endomembrane system (inferred) ; endoplasmic reticulum (inferred) | | | | Naked Mole-Rat | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626050405 | Zdhhc12 | zDHHC palmitoyltransferase 12 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN gephyrin clustering involved in postsynaptic density assembly (ortholog); negative regulation of NLRP3 inflammasome complex assembly (ortholog); peptidyl -L-cysteine S-palmitoylation (ortholog); FOUND IN dendritic spine (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1309736 | Zdhhc13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (ortholog); palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyloidosis (ortholog); Experimental Live r Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,4-dinitrotoluene | 1 | 107623599 | 107662178 | Rat | 95 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1320234 | ZDHHC13 | zDHHC palmitoyltransferase 13 | Predicted to enable magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Involved in positive regulation of canonical NF-kappaB signal transduction. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 19117104 | 19176415 | Human | 95 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1320235 | Zdhhc13 | zinc finger, DHHC domain containing 13 | Enables magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Predicted to be involved in magnesium ion transmembrane transport. Located in Golgi membrane and Golgi-associated vesicle membrane. Is expressed in several structures, including early conceptus; esophagus epi thelium; genitourinary system; molar; and sensory organ. Used to study Huntington's disease. Orthologous to human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 48438751 | 48477188 | Mouse | 143 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8724488 | Zdhhc13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (ortholog); palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyloidosis (ortholog); Experimental Live r Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | NW_004955476 | 105347 | 152415 | Chinchilla | 14 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11980261 | ZDHHC13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | 11 | 19143181 | 19202424 | Bonobo | 24 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12351753 | ZDHHC13 | zinc finger DHHC-type palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | 21 | 41243214 | 41292458 | Dog | 23 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12441349 | Zdhhc13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | NW_004936654 | 220391 | 267383 | Squirrel | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14238593 | ZDHHC13 | zinc finger DHHC-type palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | | | | Pig | 23 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18617564 | ZDHHC13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | | | | Green Monkey | 24 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18912631 | Zdhhc13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits acyltransferase activity (inferred); magnesium ion transmembrane transporter activity (inferred); palmitoyltransferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyl oidosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred) | | | | Naked Mole-Rat | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626008110 | Zdhhc13 | zDHHC palmitoyltransferase 13 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (ortholog); palmitoyltransferase activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH alopecia (ortholog); amyloidosis (ortholog); Experimental Live r Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | | | | Black Rat | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1352800 | ZDHHC14 | zDHHC palmitoyltransferase 14 | Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 157381190 | 157678157 | Human | 114 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1558404 | Zdhhc14 | zinc finger, DHHC domain containing 14 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and endopl asmic reticulum. Is expressed in oocyte. Orthologous to human ZDHHC14 (zinc finger DHHC-type palmitoyltransferase 14). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 5542220 | 5810517 | Mouse | 120 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565877 | Zdhhc14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 1 | 48473860 | 48746201 | Rat | 112 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9024223 | Zdhhc14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | NW_004955439 | 4617654 | 4893090 | Chinchilla | 3 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11754354 | ZDHHC14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); membrane (inferred) | 6 | 155265511 | 155566706 | Bonobo | 14 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12175787 | ZDHHC14 | zinc finger DHHC-type palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | 1 | 46943515 | 47220907 | Dog | 13 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12577717 | Zdhhc14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); membrane (inferred) | NW_004936489 | 9407185 | 9599783 | Squirrel | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14122739 | ZDHHC14 | zinc finger DHHC-type palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred) | | | | Pig | 14 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18361149 | ZDHHC14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); membrane (inferred) | | | | Green Monkey | 14 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18927987 | Zdhhc14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); membrane (inferred) | | | | Naked Mole-Rat | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625933264 | Zdhhc14 | zDHHC palmitoyltransferase 14 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog) | | | | Black Rat | 3 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1345155 | ZDHHC15 | zDHHC palmitoyltransferase 15 | The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for thi s gene. [provided by RefSeq, Sep 2009] | X | 75368427 | 75523037 | Human | 75 | symbol , old_gene_name , COSMIC , name , description , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1558080 | Zdhhc15 | zinc finger, DHHC domain containing 15 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Acts upstream of or within establishment of protein localization and synaptic vesicle maturation. Located in Golgi apparatus. Is expressed in embryo and eye. Orthologous to human ZDHH 'font-weight:700;'>DHHC15 (zinc finger DHHC-type palmitoyltransferase 15). [provided by Alliance of Genome Resources, Jul 2025] | X | 103580575 | 103714696 | Mouse | 89 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562075 | Zdhhc15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of dendrite development; protein localization to postsynapse; regulation of dendritic spine morphogenesi s; ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane; plasma membrane; postsynapse; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; atrazine | X | 73633977 | 73767451 | Rat | 80 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8867700 | Zdhhc15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of dendrite development (ortholog) ; ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); plasma membrane (ortholog) | NW_004955562 | 1468373 | 1588298 | Chinchilla | 25 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11940179 | ZDHHC15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane (ortholog); plasma membrane (ortholog); postsynapse (ortholog) | X | 64624908 | 64777305 | Bonobo | 29 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12307834 | ZDHHC15 | zinc finger DHHC-type palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane (ortholog); plasma membrane (ortholog); postsynapse (ortholog); INTERACTS WITH bisphenol A | X | 58641182 | 58812671 | Dog | 34 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12671660 | Zdhhc15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane (ortholog); plasma membrane (ortholog); postsynapse (ortholog) | NW_004936683 | 1482968 | 1576969 | Squirrel | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13974029 | ZDHHC15 | zinc finger DHHC-type palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane (ortholog); plasma membrane (ortholog); postsynapse (ortholog) | | | | Pig | 34 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18757915 | ZDHHC15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi membrane (ortholog); plasma membrane (ortholog); postsynapse (ortholog) | | | | Green Monkey | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18935486 | Zdhhc15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulati on of dendrite development (ortholog); ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20866716 | ZDHHC15 | zinc finger DHHC-type palmitoyltransferase 15 | | | | | Green Monkey | | symbol , old_gene_name , name | gene, protein-coding |
| 625841076 | Zdhhc15 | zDHHC palmitoyltransferase 15 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN establishment of protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of dendrite development (ortholog) ; ASSOCIATED WITH non-syndromic X-linked intellectual disability 91 (ortholog); oculocutaneous albinism type IB (ortholog); spastic diplegia (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); plasma membrane (ortholog) | | | | Black Rat | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1591893 | Zdhhc16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amit role; bisphenol A | 1 | 250694922 | 250706319 | Rat | 74 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1604262 | ZDHHC16 | zDHHC palmitoyltransferase 16 | Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025] | 10 | 97446175 | 97457370 | Human | 83 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1623929 | Zdhhc16 | zinc finger, DHHC domain containing 16 | Enables palmitoyltransferase activity. Involved in several processes, including DNA damage response; eye development; and protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including early conceptus; eye; genitourinary system; heart; and trunk somite. Orthologous to human ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 41921884 | 41932543 | Mouse | 101 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8835831 | Zdhhc16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH intellectual disability (ortholog) | NW_004955507 | 3583306 | 3593222 | Chinchilla | 11 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11720918 | ZDHHC16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred) | 10 | 94068816 | 94079732 | Bonobo | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12249232 | ZDHHC16 | zinc finger DHHC-type palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred) | 28 | 10739043 | 10749121 | Dog | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12689542 | Zdhhc16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred) | NW_004936636 | 2221254 | 2230587 | Squirrel | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14235159 | ZDHHC16 | zinc finger DHHC-type palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred) | | | | Pig | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18577755 | ZDHHC16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein palmitoylation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN membrane (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18912236 | Zdhhc16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN DNA damage response (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH intellectu al disability (ortholog); FOUND IN membrane (inferred) | | | | Naked Mole-Rat | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625968802 | Zdhhc16 | zDHHC palmitoyltransferase 16 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH intellectual disability (ortholog) | | | | Black Rat | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1351838 | ZDHHC17 | zDHHC palmitoyltransferase 17 | Enables identical protein binding activity and protein-cysteine S-palmitoyltransferase activity. Involved in lipoprotein transport; protein palmitoylation; and regulation of programmed cell death. Located in Golgi membrane and Golgi-associated vesicle membrane. [provided by Alliance of Genome Resour ces, Jul 2025] | 12 | 76764115 | 76853701 | Human | 101 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557918 | Zdhhc17 | zinc finger, DHHC domain containing 17 | Enables palmitoyltransferase activity and signaling receptor binding activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of modification of synapse structure, modulating synaptic transmission; and regulation of signal transduction. Located in Golgi app aratus. Is active in glutamatergic synapse; perforant pathway to dendrate granule cell synapse; and postsynaptic Golgi apparatus. Is expressed in several structures, including early conceptus; heart; and oocyte. Used to study Huntington's disease. Orthologous to human ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 110777640 | 110848587 | Mouse | 126 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1595790 | Zdhhc17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits identical protein binding (ortholog); palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN axonogenesis (ortholog); lipoprotein transport (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIA TED WITH Huntington's disease (ortholog); FOUND IN glutamatergic synapse (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 7 | 48256269 | 48320000 | Rat | 119 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 8916163 | Zdhhc17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits identical protein binding (ortholog); palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN axonogenesis (ortholog); lipoprotein transport (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIA TED WITH Huntington's disease (ortholog); FOUND IN glutamatergic synapse (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | NW_004955405 | 15915756 | 15997777 | Chinchilla | 36 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11702144 | ZDHHC17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits acyltransferase activity (inferred); identical protein binding (inferred); palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); protein palmito ylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); glutamatergic synapse (inferred) | 12 | 74281716 | 74371885 | Bonobo | 42 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12435785 | ZDHHC17 | zinc finger DHHC-type palmitoyltransferase 17 | ENCODES a protein that exhibits acyltransferase activity (inferred); identical protein binding (inferred); palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); protein palmito ylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); glutamatergic synapse (inferred) | 15 | 19631719 | 19727089 | Dog | 42 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12539788 | Zdhhc17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits acyltransferase activity (inferred); identical protein binding (inferred); palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); protein palmito ylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); glutamatergic synapse (inferred) | NW_004936568 | 4959796 | 5052254 | Squirrel | 43 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14066775 | ZDHHC17 | zinc finger DHHC-type palmitoyltransferase 17 | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN glutamatergic synapse (ortholog); perforant pathway to dendrate granule cell synapse (ortholog); postsynaptic Golgi apparatus (ortholog) | | | | Pig | 42 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18614770 | ZDHHC17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits acyltransferase activity (inferred); identical protein binding (inferred); palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); protein palmito ylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); glutamatergic synapse (inferred) | | | | Green Monkey | 42 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18911248 | Zdhhc17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN axonogenesis (ortholog); lipoprotein transport (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIATED WITH Huntington's disease (ortholog); FOUND IN glutamatergic synapse (ortholog); Golgi apparatus (ortholog); Golgi-associated vesicle membrane (ortholog) | | | | Naked Mole-Rat | 41 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626015055 | Zdhhc17 | zDHHC palmitoyltransferase 17 | ENCODES a protein that exhibits identical protein binding (ortholog); palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN axonogenesis (ortholog); lipoprotein transport (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); ASSOCIA TED WITH Huntington's disease (ortholog); FOUND IN glutamatergic synapse (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog) | | | | Black Rat | 36 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1309334 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of innate immune respo nse (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 151105303 | 151143843 | Rat | 96 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1319625 | ZDHHC18 | zDHHC palmitoyltransferase 18 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in negative regulation of cGAS/STING signaling pathway; negative regulation of innate immune response; and peptidyl-L-cysteine S-palmitoylation. Located in cytosol. Is active in Golgi apparatus. [provided by Alliance of Genome Resour ces, Jul 2025] | 1 | 26826688 | 26857604 | Human | 86 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551232 | Zdhhc18 | zinc finger, DHHC domain containing 18 | Enables palmitoyltransferase activity. Acts upstream of or within protein localization. Predicted to be located in Golgi membrane and cytosol. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC18 (zinc finger DHH yle='font-weight:700;'>DHHC-type palmitoyltransferase 18). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 133331969 | 133360801 | Mouse | 97 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9047826 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of innate immune respo nse (ortholog); FOUND IN Golgi apparatus (ortholog) | NW_004955452 | 6176077 | 6211669 | Chinchilla | 9 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11891231 | ZDHHC18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN intracellular protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi appar atus (ortholog) | 1 | 26087242 | 26120896 | Bonobo | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12362475 | ZDHHC18 | zinc finger DHHC-type palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN intracellular protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi appar atus (inferred); membrane (inferred) | 2 | 73274186 | 73297375 | Dog | 17 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12555215 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN intracellular protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi appar atus (ortholog) | NW_004936474 | 11246540 | 11272167 | Squirrel | 19 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13886424 | ZDHHC18 | zinc finger DHHC-type palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN intracellular protein localization (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi appar atus (inferred); membrane (inferred) | | | | Pig | 18 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18585374 | ZDHHC18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of innate immune respo nse (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Green Monkey | 9 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18935947 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negat ive regulation of innate immune response (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Naked Mole-Rat | 15 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20865673 | ZDHHC18 | zinc finger DHHC-type palmitoyltransferase 18 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN negative regulation of cGAS/STING signaling pathway (inferred); negative regulation of innate immune response (infer red); protein targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name | gene, protein-coding |
| 625944474 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of innate immune respo nse (ortholog); FOUND IN Golgi apparatus (ortholog) | | | | Black Rat | 9 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1309014 | Zdhhc19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of aggrephagy (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi membrane (ortholog); perinucleolar compartment (ort holog); INTERACTS WITH bisphenol A; dibutyl phthalate; furan | 11 | 81782899 | 81794105 | Rat | 66 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319120 | Zdhhc19 | zinc finger, DHHC domain containing 19 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation; positive regulation of aggrephagy; and protein targeting to membrane. Predicted to be located in Golgi membrane and perinucleolar compartment. Predicted to be activ e in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC19 (zinc finger DHHC-type palmitoyltransferase 19). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 32315059 | 32326032 | Mouse | 89 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1346417 | ZDHHC19 | zDHHC palmitoyltransferase 19 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation and positive regulation of aggrephagy. Located in Golgi membrane; endoplasmic reticulum; and perinucleolar compartment. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 196197452 | 196211400 | Human | 61 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8870318 | Zdhhc19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of aggrephagy (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi membrane (ortholog); perinucleolar compartment (ort holog) | NW_004955420 | 12432342 | 12442411 | Chinchilla | 9 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11963926 | ZDHHC19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); Golgi membrane (inferred) | 3 | 193537735 | 193551564 | Bonobo | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12263725 | ZDHHC19 | zinc finger DHHC-type palmitoyltransferase 19 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi membrane (inferred ); membrane (inferred) | 33 | 29332947 | 29335942 | Dog | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 14169062 | ZDHHC19 | zinc finger DHHC-type palmitoyltransferase 19 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi membrane (inferred ); membrane (inferred) | | | | Pig | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18719072 | ZDHHC19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferre d); Golgi membrane (inferred) | | | | Green Monkey | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18912954 | Zdhhc19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of aggrephagy (ortholog); FOUND IN Golgi membra ne (ortholog); perinucleolar compartment (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 18 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626017166 | Zdhhc19 | zDHHC palmitoyltransferase 19 | ENCODES a protein that exhibits protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of aggrephagy (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi membrane (ortholog); perinucleolar compartment (ort holog) | | | | Black Rat | 9 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1305755 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (ortholog); nucleus (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 15 | 36095624 | 36154546 | Rat | 85 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1553018 | Zdhhc20 | zinc finger, DHHC domain containing 20 | Predicted to enable protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Predicted to be involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation by host of viral process; and synaptic vesicle maturation. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 58070159 | 58128288 | Mouse | 109 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606124 | ZDHHC20 | zDHHC palmitoyltransferase 20 | Enables protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Involved in peptidyl-L-cysteine S-palmitoylation and positive regulation by host of viral process. Located in Golgi membrane and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 13 | 21372571 | 21459303 | Human | 94 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9055010 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (ortholog); nucleus (ortholog); plasma membrane (ortholog) | NW_004955497 | 1913802 | 1948356 | Chinchilla | 11 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11865101 | ZDHHC20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (inferre d); membrane (inferred); nucleus (inferred) | 13 | 2671177 | 2756033 | Bonobo | 18 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12197184 | ZDHHC20 | zinc finger DHHC-type palmitoyltransferase 20 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (inferre d); membrane (inferred); nucleus (inferred) | 25 | 16883185 | 16960907 | Dog | 22 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12480064 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (inferre d); membrane (inferred); nucleus (inferred) | NW_004936720 | 501835 | 576849 | Squirrel | 18 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14286311 | ZDHHC20 | zinc finger DHHC-type palmitoyltransferase 20 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (inferre d); kinetochore (inferred); membrane (inferred) | | | | Pig | 29 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18711320 | ZDHHC20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (inferre d); membrane (inferred); nucleus (inferred) | | | | Green Monkey | 18 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18921646 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (ortholog); nucleus (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625894747 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (ortholog); nucleus (ortholog); plasma membrane (ortholog) | | | | Black Rat | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1305750 | Zdhhc21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN adrenergic receptor signaling pathway (ortholog); hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi a pparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 5 | 102273561 | 102333174 | Rat | 106 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1313969 | ZDHHC21 | zDHHC palmitoyltransferase 21 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 14588797 | 14693432 | Human | 113 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1313970 | Zdhhc21 | zinc finger, DHHC domain containing 21 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of establishment of endothelial barrier; and regulation of vascular associated smooth muscle contraction. Acts upstream of or within hair follicle devel opment; protein palmitoylation; and sebaceous gland development. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; eye; inner cell mass; oocyte; and trunk somite. Orthologous to human ZDHHC21 (zinc finger DHHC-type palmitoyltransferase 21). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 82716975 | 82778892 | Mouse | 132 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9064667 | Zdhhc21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN adrenergic receptor signaling pathway (ortholog); hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi a pparatus (ortholog); plasma membrane (ortholog) | NW_004955434 | 17653708 | 17712565 | Chinchilla | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11760039 | ZDHHC21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortho log); FOUND IN Golgi apparatus (inferred); membrane (inferred); plasma membrane (inferred) | 9 | 14430035 | 14528888 | Bonobo | 21 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12099272 | ZDHHC21 | zinc finger DHHC-type palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortho log); FOUND IN Golgi apparatus (inferred); membrane (inferred); plasma membrane (inferred) | 11 | 35073639 | 35139854 | Dog | 24 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12445022 | Zdhhc21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortho log); FOUND IN Golgi apparatus (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936539 | 8243134 | 8304811 | Squirrel | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13877819 | ZDHHC21 | zinc finger DHHC-type palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortho log); FOUND IN Golgi apparatus (inferred); membrane (inferred); plasma membrane (inferred) | | | | Pig | 24 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18344455 | ZDHHC21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortho log); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Green Monkey | 25 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18929332 | Zdhhc21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN adrenergic receptor signaling pathway (ortholog); hair follicle development (ortholog); peptidyl-L-cysteine S-palmit oylation (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625855276 | Zdhhc21 | zDHHC palmitoyltransferase 21 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN adrenergic receptor signaling pathway (ortholog); hair follicle development (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); FOUND IN Golgi a pparatus (ortholog); plasma membrane (ortholog) | | | | Black Rat | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1308446 | Zdhhc22 | zDHHC palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (ortholog); Golgi apparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 6 | 112360051 | 112377950 | Rat | 55 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1318218 | ZDHHC22 | zDHHC palmitoyltransferase 22 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 77131270 | 77142288 | Human | 52 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1620581 | Zdhhc22 | zinc finger, DHHC-type containing 22 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Acts upstream of or within protein localization to plasma membrane and protein palmitoylation. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human Z DHHC22 (zinc finger DHHC-type palmitoyltransferase 22). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 87027537 | 87037604 | Mouse | 58 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9065100 | Zdhhc22 | zDHHC palmitoyltransferase 22 | INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); plasma membrane (ortholog) | NW_004955438 | 1048072 | 1058142 | Chinchilla | 9 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11772427 | ZDHHC22 | zDHHC palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | 14 | 57681164 | 57698136 | Bonobo | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12171352 | ZDHHC22 | zinc finger DHHC-type palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | 8 | 49961013 | 49971688 | Dog | 19 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12696986 | Zdhhc22 | zDHHC palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | NW_004936488 | 5967835 | 5977830 | Squirrel | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13976596 | ZDHHC22 | zinc finger DHHC-type palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Pig | 20 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18664380 | ZDHHC22 | zDHHC palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18901964 | Zdhhc22 | zDHHC palmitoyltransferase 22 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulu m (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Naked Mole-Rat | 15 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625969866 | Zdhhc22 | zDHHC palmitoyltransferase 22 | INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); plasma membrane (ortholog) | | | | Black Rat | 9 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1303254 | Zdhhc23 | zDHHC palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,4-dinitrotoluene | 11 | 70224581 | 70240971 | Rat | 90 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1345232 | ZDHHC23 | zDHHC palmitoyltransferase 23 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resour ces, Jul 2025] | 3 | 113947901 | 113979508 | Human | 90 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1618774 | Zdhhc23 | zinc finger, DHHC domain containing 23 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Acts upstream of or within protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including central nervous system; ileum; metanephros; reproductive system; and respiratory system. Orthologous to human ZDHHC23 (zinc finger DHHC-type palmitoyltransferase 23). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 43785396 | 43800295 | Mouse | 92 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8732939 | Zdhhc23 | zDHHC palmitoyltransferase 23 | INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog) | NW_004955427 | 14045659 | 14057226 | Chinchilla | 6 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11982559 | ZDHHC23 | zDHHC palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred) | 3 | 111086166 | 111101631 | Bonobo | 17 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12091490 | ZDHHC23 | zinc finger DHHC-type palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN Golgi apparatus (inferred) | 33 | 18215822 | 18227626 | Dog | 16 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12614483 | Zdhhc23 | zDHHC palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred) | NW_004936536 | 1434774 | 1450872 | Squirrel | 17 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13881994 | ZDHHC23 | zinc finger DHHC-type palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN Golgi apparatus (inferred) | | | | Pig | 17 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18474317 | ZDHHC23 | zDHHC palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred) | | | | Green Monkey | 17 | symbol , old_gene_name , name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18926627 | Zdhhc23 | zDHHC palmitoyltransferase 23 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred) | | | | Naked Mole-Rat | 17 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625943426 | Zdhhc23 | zDHHC palmitoyltransferase 23 | INVOLVED IN protein localization to plasma membrane (ortholog); protein palmitoylation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog) | | | | Black Rat | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1557474 | Zdhhc24 | zinc finger, DHHC domain containing 24 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including brain; early concep tus; endocrine gland; genitourinary system; and spinal cord mantle layer. Orthologous to human ZDHHC24 (zinc finger DHHC-type containing 24). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 4928696 | 4935425 | Mouse | 46 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565630 | Zdhhc24 | zDHHC palmitoyltransferase 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon | 1 | 211605163 | 211612267 | Rat | 40 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1602172 | ZDHHC24 | zDHHC palmitoyltransferase 24 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 66520625 | 66546048 | Human | 41 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8891266 | Zdhhc24 | zDHHC palmitoyltransferase 24 | ASSOCIATED WITH retinitis pigmentosa (ortholog) | NW_004955422 | 18813325 | 18819878 | Chinchilla | 3 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11865001 | ZDHHC24 | zDHHC palmitoyltransferase 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein targeting to membrane (inferred); ASSOCIATED WITH retinitis pigmentosa (ortholog); FOUND IN endoplasmic reti culum (inferred); Golgi apparatus (inferred); membrane (inferred) | 11 | 61887816 | 61905130 | Bonobo | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12319392 | ZDHHC24 | zinc finger DHHC-type containing 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); ASSOCIATED WITH retinitis pigmentosa (ortholog); FOUND IN membrane (inferred) | 18 | 50801179 | 50808480 | Dog | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12589573 | Zdhhc24 | zDHHC palmitoyltransferase 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein targeting to membrane (inferred); ASSOCIATED WITH retinitis pigmentosa (ortholog); FOUND IN endoplasmic reti culum (inferred); Golgi apparatus (inferred); membrane (inferred) | NW_004936599 | 3047011 | 3054512 | Squirrel | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14080978 | ZDHHC24 | zinc finger DHHC-type containing 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); ASSOCIATED WITH retinitis pigmentosa (ortholog); FOUND IN membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18763415 | ZDHHC24 | zDHHC palmitoyltransferase 24 | ASSOCIATED WITH retinitis pigmentosa (ortholog) | | | | Green Monkey | 3 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18905464 | Zdhhc24 | zDHHC palmitoyltransferase 24 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein targeting to membrane (inferred); ASSOCIATED WITH retinitis pigmentosa (ortholog); FOUND IN endoplasmic reti culum (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Naked Mole-Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626067240 | Zdhhc24 | zDHHC palmitoyltransferase 24 | | | | | Black Rat | 2 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1558490 | Zdhhc25 | zinc finger, DHHC domain containing 25 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein localization to plasma membrane; protein targeting to membrane; and regulation of G protein-coupled receptor signaling pathway. Predicted to be active in Golgi apparatus and endoplasmic reticulu m. Is expressed in testis. [provided by Alliance of Genome Resources, Jul 2025] | 15 | 88484505 | 88485872 | Mouse | 15 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1598341 | Zdhhc25 | zinc finger, DHHC-type containing 25 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; cadmium dichloride | 7 | 121572354 | 121573586 | Rat | 14 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1602781 | ZDHHC11B | zDHHC palmitoyltransferase 11B (putative) | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in several processes, including antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Predicted to be located in endosome mem brane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 710355 | 784729 | Human | 23 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16553450 | ZDHHC1P1 | ZDHHC1 pseudogene 1 | | | | | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, processed_pseudogene |
| 4891558 | ZDHHC4P1 | ZDHHC4 pseudogene 1 | | 13 | 42933680 | 42934932 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604989 | ZDHHC8BP | ZDHHC8B, pseudogene | INTERACTS WITH 17beta-estradiol; acrylamide; all-trans-retinoic acid | 22 | 23390605 | 23402612 | Human | 23 | symbol , old_gene_name , COSMIC , name , ensembl_full_name , Human Proteome Map , old_gene_symbol | gene, pseudo, VALIDATED [RefSeq] |
| 5134875 | ZDHHC20P1 | ZDHHC20 pseudogene 1 | | 6 | 29708141 | 29708547 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5134855 | ZDHHC20P2 | ZDHHC20 pseudogene 2 | | 6 | 31380408 | 31380839 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6481063 | ZDHHC20P3 | ZDHHC20 pseudogene 3 | | 11 | 75228314 | 75228652 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5130599 | ZDHHC20P4 | ZDHHC20 pseudogene 4 | | 13 | 68984858 | 68986526 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 2324088 | Zdhhc16-ps1 | zinc finger DHHC-type palmitoyltransferase 16, pseudogene 1 | | X | 58097956 | 58098510 | Rat | | symbol , old_gene_name , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 732708 | COQ3 | coenzyme Q3, methyltransferase | Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008] | 6 | 99369401 | 99394195 | Human | 138 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11752173 | LOC100991557 | palmitoyltransferase ZDHHC8 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN locomotory behavior (ortholog); regulation of postsynapse assembly (ortholog); FOUND IN glutamatergic synapse (ortho log); mitochondrion (ortholog); postsynapse (ortholog) | | | | Bonobo | 17 | old_gene_name , name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934188 | LOC101704315 | probable palmitoyltransferase ZDHHC11 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN protein targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred); mem brane (inferred) | | | | Naked Mole-Rat | 10 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12551442 | LOC101961319 | palmitoyltransferase ZDHHC11 | ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); positive regulation of defense response to virus by host (inferred); pr otein targeting to membrane (inferred); FOUND IN endoplasmic reticulum (inferred); endosome membrane (inferred); Golgi apparatus (inferred) | NW_004936815 | 764708 | 790694 | Squirrel | 15 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12693804 | LOC101977244 | zinc finger DHHC-type palmitoyltransferase 19 | ENCODES a protein that exhibits protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of aggrephagy (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi membrane (ortholog); perinucleolar compartment (ort holog) | NW_004936784 | 748381 | 833841 | Squirrel | 9 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8957602 | LOC102024592 | tubulin polymerization-promoting protein | | NW_004955504 | 341155 | 416050 | Chinchilla | | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11763064 | LOC103785123 | palmitoyltransferase ZDHHC11 | | 1 | 123870855 | 123920855 | Bonobo | | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16565132 | AC020914.5 | ZDHHC7 zinc finger, DHHC-type containing 7 (ZDHHC7) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 2380 | Coq3 | coenzyme Q3 methyltransferase | ENCODES a protein that exhibits 3-demethylubiquinol 3-O-methyltransferase activity (ortholog); 3-demethylubiquinone 3-O-methyltransferase activity (ortholog); O-methyltransferase activity (ortholog); INVOLVED IN methylation; ubiquinone biosynthetic process; glycerol metabolic process (ortholog); PAR TICIPATES IN ubiquinone biosynthetic pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,4-dinitrotoluene | 5 | 40226313 | 40257383 | Rat | 141 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 737404 | Coq3 | coenzyme Q3 methyltransferase | Predicted to enable 3-demethylubiquinol 3-O-methyltransferase activity and polyprenyldihydroxybenzoate methyltransferase activity. Predicted to be involved in glycerol metabolic process; methylation; and ubiquinone biosynthetic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in heart and heart right ventricle. Orthologous to human COQ3 (coenzyme Q3, methyltransferase). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 21879646 | 21912163 | Mouse | 159 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1354359 | HHIP | hedgehog interacting protein | This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetr y in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011] | 4 | 144646156 | 144745271 | Human | 161 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1350944 | PRUNE1 | prune exopolyphosphatase 1 | This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases throu gh the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] | 1 | 151008449 | 151035713 | Human | 161 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 16559161 | AC112203.1 | novel DHHC-type zinc finger pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 38622786 | LOC100420774 | zDHHC palmitoyltransferase 6 pseudogene | | 2 | 73877182 | 73877819 | Human | | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 38622419 | LOC391813 | zDHHC palmitoyltransferase 3 pseudogene | | 5 | 97737719 | 97738724 | Human | | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 16565022 | AC063977.4 | zinc finger, DHHC-type containing 7 (ZDHHC7) pseudogene | | 19 | 51194120 | 51195555 | Human | | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 16566008 | AC073046.2 | zinc finger, DHHC-type containing 6 (ZDHHC6) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16560179 | AC124290.3 | zinc finger, DHHC-type containing 7 (ZDHHC7) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 12254954 | COQ3 | coenzyme Q3, methyltransferase | ENCODES a protein that exhibits 3-demethylubiquinol 3-O-methyltransferase activity (inferred); 3-demethylubiquinone 3-O-methyltransferase activity (inferred); metal ion binding (inferred); INVOLVED IN methylation (ortholog); ubiquinone biosynthetic process (ortholog); PARTICIPATES IN ubiquinone bios ynthetic pathway; FOUND IN extrinsic component of mitochondrial inner membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial matrix (inferred) | 12 | 57589993 | 57606486 | Dog | 34 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1322864 | ZCCHC4 | zinc finger CCHC-type containing 4 | Enables S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Jul 2025] | 4 | 25312774 | 25370383 | Human | 56 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1347083 | KMT2C | lysine methyltransferase 2C | This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger . This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008] | 7 | 152134925 | 152436003 | Human | 322 | description | gene, protein-coding, REVIEWED [RefSeq] |