Zdhhc6 (zinc finger DHHC-type palmitoyltransferase 6)

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Gene: Zdhhc6 (zinc finger DHHC-type palmitoyltransferase 6) Rattus norvegicus

Analyze

Symbol:

Zdhhc6

Name:

zinc finger DHHC-type palmitoyltransferase 6

RGD ID:

1304657

Description:

Predicted to enable protein-cysteine S-palmitoyltransferase activity and protein-cysteine S-stearoyltransferase activity. Predicted to be involved in positive regulation of mitochondrial fusion; protein lipidation; and protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6); INTERACTS WITH 2-amino-4,6-dinitrotoluene; bisphenol A; gentamycin.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC361771; membrane-associated DHHC6 zinc finger protein; MGC125041; palmitoyltransferase ZDHHC6; probable palmitoyltransferase ZDHHC6; zinc finger, DHHC domain containing 6; zinc finger, DHHC-type containing 6

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Zdhhc6 (zinc finger, DHHC domain containing 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Zdhhc6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zdhhc6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zdhhc6 (zinc finger DHHC-type palmitoyltransferase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zdhhc6 (zinc finger, DHHC domain containing 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zdhhc6 (zinc finger, DHHC-type containing 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PFA4	Alliance	DIOPT (Hieranoid\|PANTHER)
Drosophila melanogaster (fruit fly):	CG4483	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5196	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dhhc-6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	254,335,472 - 254,356,141 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	254,335,113 - 254,356,108 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	262,542,990 - 262,561,093 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	269,249,070 - 269,267,173 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	261,896,678 - 261,914,775 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	276,291,411 - 276,309,633 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	276,291,417 - 276,309,099 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	283,686,766 - 283,704,988 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	261,600,778 - 261,606,354 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	261,815,641 - 261,864,000 (-)	NCBI
Celera	1	250,044,717 - 250,062,813 (-)	NCBI		Celera
Cytogenetic Map	1	q55	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-amino-4,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

4,4'-diaminodiphenylmethane (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

cadmium sulfate (ISO)

carbon nanotube (ISO)

clofibrate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

deguelin (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

folic acid (ISO)

gentamycin (EXP)

leflunomide (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

tert-butyl hydroperoxide (ISO)

thioacetamide (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

peptidyl-L-cysteine S-palmitoylation (IBA)

positive regulation of mitochondrial fusion (ISO)

protein palmitoylation (ISO)

protein stearoylation (ISO)

protein targeting to membrane (IBA)

Cellular Component

endoplasmic reticulum (IBA,ISO)

Golgi apparatus (IBA)

membrane (IEA)

Molecular Function

palmitoyltransferase activity (ISO)

protein binding (ISO)

protein-cysteine S-palmitoyltransferase activity (IBA)

protein-cysteine S-stearoyltransferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16647879	PMID:21926431	PMID:22728137	PMID:23034182	PMID:25368151	PMID:26214738	PMID:28826475

Genomics

Comparative Map Data

Zdhhc6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	254,335,472 - 254,356,141 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	254,335,113 - 254,356,108 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	262,542,990 - 262,561,093 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	269,249,070 - 269,267,173 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	261,896,678 - 261,914,775 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	276,291,411 - 276,309,633 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	276,291,417 - 276,309,099 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	283,686,766 - 283,704,988 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	261,600,778 - 261,606,354 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	261,815,641 - 261,864,000 (-)	NCBI
Celera	1	250,044,717 - 250,062,813 (-)	NCBI		Celera
Cytogenetic Map	1	q55	NCBI

ZDHHC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	112,424,412 - 112,447,572 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	10	112,424,428 - 112,447,572 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	114,184,170 - 114,207,330 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	114,180,048 - 114,196,662 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	114,180,049 - 114,196,662	NCBI
Celera	10	107,917,581 - 107,934,195 (-)	NCBI		Celera
Cytogenetic Map	10	q25.2	NCBI
HuRef	10	107,817,705 - 107,834,321 (-)	NCBI		HuRef
CHM1_1	10	114,471,789 - 114,488,322 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	113,315,089 - 113,338,239 (-)	NCBI		T2T-CHM13v2.0

Zdhhc6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	55,286,648 - 55,304,468 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	55,259,723 - 55,304,464 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	55,298,216 - 55,316,036 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	55,271,291 - 55,316,032 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	55,372,786 - 55,390,522 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	55,351,546 - 55,369,282 (-)	NCBI		MGSCv36	mm8
Celera	19	57,489,435 - 57,507,165 (-)	NCBI		Celera
Cytogenetic Map	19	D2	NCBI

Zdhhc6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	17,525,752 - 17,542,539 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	17,525,752 - 17,542,540 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZDHHC6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	112,459,817 - 112,476,704 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	112,457,937 - 112,474,921 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	109,021,160 - 109,038,445 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ZDHHC6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	23,479,978 - 23,494,977 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	23,478,813 - 23,494,977 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	23,631,751 - 23,648,073 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	24,012,445 - 24,028,769 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	24,011,287 - 24,028,764 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	23,569,510 - 23,585,821 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	23,580,670 - 23,596,983 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	23,777,122 - 23,793,450 (-)	NCBI		UU_Cfam_GSD_1.0

Zdhhc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	22,551,206 - 22,567,759 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	2,993,473 - 3,010,096 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936486	2,993,519 - 3,010,101 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZDHHC6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	122,824,817 - 122,848,579 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	122,831,197 - 122,848,599 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	134,028,677 - 134,046,078 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZDHHC6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	105,313,392 - 105,329,967 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	105,313,899 - 105,330,069 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	66,516,516 - 66,533,106 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zdhhc6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	34,021,080 - 34,037,248 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	34,021,038 - 34,037,248 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Zdhhc6
20 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	246
Count of miRNA genes:	164
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000054681
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	214647894	259647894	Rat
1549910	Bw54	Body weight QTL 54		0.05	body mass (VT:0001259)	body weight (CMO:0000012)	1	214647894	259647894	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	216255568	260522016	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	216255568	260522016	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	218748008	257976495	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	218753816	256448513	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	221264111	259647894	Rat
10053715	Scort24	Serum corticosterone level QTL 24	2.13	0.0088	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	221414816	260522016	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	222363780	260522016	Rat
1600392	Bw123	Body weight QTL 123		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	223201027	260522016	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	224054293	260122809	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	224054293	260122809	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	224569538	260122809	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	225126575	260522016	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	228581588	259647894	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	232156370	259647894	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233190394	258625266	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	233948574	260522016	Rat
631690	Scl5	Serum cholesterol level QTL 5	2.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	236125214	260522016	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	0.00000487	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	237147813	260522016	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	238699859	259647894	Rat
1598839	Rf56	Renal function QTL 56			renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	245907761	257976495	Rat

Markers in Region

RH131335

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	254,338,013 - 254,338,222 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	276,291,418 - 276,291,626	NCBI	Rnor6.0
Rnor_5.0	1	283,686,773 - 283,686,981	UniSTS	Rnor5.0
RGSC_v3.4	1	261,600,785 - 261,600,993	UniSTS	RGSC3.4
Celera	1	250,044,724 - 250,044,932	UniSTS
RH 3.4 Map	1	1684.5	UniSTS
Cytogenetic Map	1	q55	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	33	57	41	19	41	3	3	74	35	40	11	3
Low		10					5	8			1		5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY886524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC107928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000054681 ⟹ ENSRNOP00000051566

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	254,338,016 - 254,356,108 (-)	Ensembl
Rnor_6.0 Ensembl	1	276,291,417 - 276,308,095 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000087680 ⟹ ENSRNOP00000074182

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	254,335,113 - 254,356,101 (-)	Ensembl
Rnor_6.0 Ensembl	1	276,291,875 - 276,309,099 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103424 ⟹ ENSRNOP00000080065

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	254,336,039 - 254,356,097 (-)	Ensembl

RefSeq Acc Id:

NM_001037652 ⟹ NP_001032741

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	254,338,007 - 254,356,101 (-)	NCBI
Rnor_6.0	1	276,291,411 - 276,309,633 (-)	NCBI
Rnor_5.0	1	283,686,766 - 283,704,988 (-)	NCBI
RGSC_v3.4	1	261,600,778 - 261,606,354 (-)	RGD
Celera	1	250,044,717 - 250,062,813 (-)	RGD

Sequence:

show sequence

CACGCCCCTGCGTGAGCCAGACACGCGCCGGTAGGAGTTGCTCGCTCGGTTCTCGCCATCAGGT
TTCGCATTCGGCTTACTCAGGACTGATGTGCTCATGACAGAGCTATAAAGAGGAGAAAATCTGT
TCCGGTGAGCCCAGGCCGCTCCGGAAATGCGATGGCCGTGGAGCGGGCACCGGAGACCAGACTG
AGACTGTGTTTCAAACCAACCAAGATTCTCCTCCTCGAGATCTGGAGGCCACCAGTGAAAATGG
CATACTCCATATCAACACCCCGTCATCCAAAGGCATGACAGACAGCTCAGGAACACGCGTGGAC
TTTTTGCACACAGAAATGTGTACACAGGAAAAGGAAATCTCTAGTTCTTTAGAAGAAAGAAGTC
ATTCTTCACCAAAATGAGCACGCTCTGCTCAGTAATCAAGTTTGAAAATCTTCAAGACTTAAGA
AGACTGTGTCATTGGGGTCCCATAATAGCCCTGGGTGTTATAGCAATATGTTCCACAATGGCCA
TGATTGACTCTGTCTTGTGGTATTGGCCCTTACATACAACTGGAGGAAGTGTGAATTTCATCAT
GTTGATAAATTGGACTGTCATGATTCTTTATAATTACTTCAATGCCATGTTTGCTGGTCCTGGC
TTCGTCCCCCGGGGCTGGAAACCGGAGAATCCTCAGGATAGCATGTATCTCCAGTATTGTAAAG
TCTGCCAAGCGTACAAGGCACCACGTTCACATCATTGCAGAAAGTGTAACAGATGTGTAATGAA
GATGGACCACCACTGTCCCTGGATCAATAACTGCTGTGGTCACCAGAACCATGCGTCCTTCACA
CTCTTCCTGCTGCTGGCCCCTCTGGGCTGCACCCATGCTGCTTTCATCTTTGTGATGACCATGT
ACACACAGCTCTATAACCGGCTCTCCTTCGGGTGGAACACAGTCAAGATTGACATGAGTGCAGC
CAGGAGAGACCCTCCTCCAATTGTTCCTTTTGGATTGGCTGCGTTTGCTGCCACCTTGTTTGCC
TTGGGATTAGCTCTGGGAACAACCATAGCTGTTGGGATGTTGTTTTTCATACAGATAAAAATTA
TTCTCAGAAACAAAACTTCTATTGAATCATGGATCGAAGAGAAGGCTAAAGATCGGATCCAGTA
TTACCAGCTGGATGAAGTCTTCGTGTTCCCTTACGATATGGGAAGTAAATGGAAGAACTTGAAG
CAGGTGTTTACATGGTCGGGAGTCCCTGAAGGAGATGGACTTGAGTGGCCAATACGAGAGGGCT
GTCACCAGTACAGCCTAACAATAGAGCAGTTGAAACAAAAAGCAGACAAGAGAGTCAGAAGTGT
CCGCTATAAGGTCGTAGAAGACTATAATGGTGCCTGTTGCCCTTTGAACCGAGGAGTCAGAACC
TTCTTCACAAGCCCCTGCACTGAGGAGCCTCGGATTCAGCTGCAGAAAGGGGAGCTCGTCTTAG
CAACCCGAGGGTTACGATACTGGTTGTATGGAGACAAAATTCTTGATGATTCCTTCATAGAAGG
TACTTCAAGAATAAGAGGGTGGTTTCCTAGAAACTGTGTAGAAAAGTGCCCCTGTGATGGAGAG
TCAGATCCAGCCCCAGAGGGCGAGAAGAAGAACAGATAGCCACGGTTAAAGTGAGATCATTACG
TCTTCATTACTTGAAAATCCACACATAGTACCTGAGAATTATGCAACAAGCCTACTATGCCTAA
GGTATTTTCCTCAAAGATGCCCTCGTGCCATGACTTCAGAAATTTTTATTACCATTTTGAAACA
GAAGCCATTCTGCATATGCCTTTGAAGTCCTGCCATCTTCCCACTTCTTCCTACTAAAGGAAGG
CCATTCCAGCCAAGTAAGCCAGCTGCCCTTTCTGTCTGCTGCACCTGTGACTTCACCTGCAGGT
CTGATTCCCACCTGGACAGGAGCATCTTGCATGTGCTTATTCTGTTTCTTCCTCAGTTGACATT
TCCTCCATAATCTAGAGACTGTAAAACCTGTCAGATTCAGTGTAAACTCAAATTTTGTTACTTT
TAATAATGCAAATTTTGTCAAATTCAATAAAGGTCAATGGATGTTCTGTAAATTAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039084676 ⟹ XP_038940604

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	254,338,013 - 254,356,138 (-)	NCBI

RefSeq Acc Id:

XM_039084677 ⟹ XP_038940605

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	254,335,472 - 254,356,141 (-)	NCBI

RefSeq Acc Id:

XM_039084679 ⟹ XP_038940607

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	254,339,180 - 254,356,140 (-)	NCBI

RefSeq Acc Id:

XM_039084680 ⟹ XP_038940608

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	254,336,420 - 254,356,140 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001032741	(Get FASTA)	NCBI Sequence Viewer
	XP_038940604	(Get FASTA)	NCBI Sequence Viewer
	XP_038940605	(Get FASTA)	NCBI Sequence Viewer
	XP_038940607	(Get FASTA)	NCBI Sequence Viewer
	XP_038940608	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI07929	(Get FASTA)	NCBI Sequence Viewer
	AAX73386	(Get FASTA)	NCBI Sequence Viewer
	EDL94468	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001032741 ⟸ NM_001037652

- UniProtKB:

Q32PY5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSTLCSVIKFENLQDLRRLCHWGPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINW
TVMILYNYFNAMFAGPGFVPRGWKPENPQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHH
CPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLSFGWNTVKIDMSAARRDP
PPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIEEKAKDRIQYYQLD
EVFVFPYDMGSKWKNLKQVFTWSGVPEGDGLEWPIREGCHQYSLTIEQLKQKADKRVRSVRYKV
VEDYNGACCPLNRGVRTFFTSPCTEEPRIQLQKGELVLATRGLRYWLYGDKILDDSFIEGTSRI
RGWFPRNCVEKCPCDGESDPAPEGEKKNR

hide sequence

RefSeq Acc Id:

ENSRNOP00000074182 ⟸ ENSRNOT00000087680

RefSeq Acc Id:

ENSRNOP00000051566 ⟸ ENSRNOT00000054681

RefSeq Acc Id:	XP_038940605 ⟸ XM_039084677
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K7F3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038940608 ⟸ XM_039084680
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038940604 ⟸ XM_039084676
- Peptide Label:	isoform X1
- UniProtKB:	Q32PY5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038940607 ⟸ XM_039084679
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSRNOP00000080065 ⟸ ENSRNOT00000103424

Protein Domains

DHHC SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K7F3-F1-model_v2	AlphaFold	A0A0G2K7F3	1-413	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304657	AgrOrtholog
BioCyc Gene	G2FUF-55345	BioCyc
Ensembl Genes	ENSRNOG00000036576	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000051566.4	UniProtKB/TrEMBL
	ENSRNOP00000074182	ENTREZGENE
	ENSRNOP00000074182.2	UniProtKB/TrEMBL
	ENSRNOP00000080065	ENTREZGENE
	ENSRNOP00000080065.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000054681.5	UniProtKB/TrEMBL
	ENSRNOT00000087680	ENTREZGENE
	ENSRNOT00000087680.2	UniProtKB/TrEMBL
	ENSRNOT00000103424	ENTREZGENE
	ENSRNOT00000103424.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7130799	IMAGE-MGC_LOAD
InterPro	SH3-like_dom	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
	Znf_DHHC_palmitoyltrfase	UniProtKB/TrEMBL
KEGG Report	rno:361771	UniProtKB/TrEMBL
MGC_CLONE	MGC:125041	IMAGE-MGC_LOAD
NCBI Gene	361771	ENTREZGENE
Pfam	SH3_2	UniProtKB/TrEMBL
	zf-DHHC	UniProtKB/TrEMBL
PhenoGen	Zdhhc6	PhenoGen
PROSITE	SH3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50044	UniProtKB/TrEMBL
UniProt	A0A0G2K7F3	ENTREZGENE, UniProtKB/TrEMBL
	F1LQB4_RAT	UniProtKB/TrEMBL
	Q32PY5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-11-11	Zdhhc6	zinc finger DHHC-type palmitoyltransferase 6	Zdhhc6	zinc finger, DHHC-type containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	Zdhhc6	zinc finger, DHHC-type containing 6	Zdhhc6	zinc finger, DHHC domain containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	Zdhhc6	zinc finger, DHHC domain containing 6	Zdhhc6_predicted	zinc finger, DHHC domain containing 6 (predicted)	Symbol and Name status set to approved	1299863	APPROVED
2005-01-12	Zdhhc6_predicted	zinc finger, DHHC domain containing 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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