DHH (desert hedgehog signaling molecule) - Rat Genome Database

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Gene: DHH (desert hedgehog signaling molecule) Sus scrofa
Analyze
Symbol: DHH
Name: desert hedgehog signaling molecule
RGD ID: 14191849
Description: ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN Leydig cell differentiation (ortholog); male gonad development (ortholog); male sex determination (ortholog); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; ASSOCIATED WITH 46,XY Partial Gonadal Dysgenesis, with Minifascicular Neuropathy (ortholog); 46,XY sex reversal (ortholog); 46,XY sex reversal 7 (ortholog); FOUND IN extracellular space (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: desert hedgehog protein
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,114,527 - 15,119,577 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,114,524 - 15,119,610 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,473,443 - 15,478,529 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
DHH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,114,527 - 15,119,577 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,114,524 - 15,119,610 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,473,443 - 15,478,529 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,086,656 - 49,094,801 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1249,086,656 - 49,094,801 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,480,439 - 49,488,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,769,471 - 47,774,869 (-)NCBINCBI36hg18NCBI36
Build 341247,769,474 - 47,774,869NCBI
Celera1248,277,990 - 48,283,388 (-)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,514,270 - 46,519,672 (-)NCBIHuRef
CHM1_11249,448,515 - 49,453,913 (-)NCBICHM1_1
T2T-CHM13v2.01249,048,829 - 49,056,982 (-)NCBI
Dhh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,779,496 - 98,796,443 (-)NCBIGRCm39mm39
GRCm39 Ensembl1598,789,033 - 98,796,421 (-)Ensembl
GRCm381598,881,615 - 98,898,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,891,152 - 98,898,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,723,458 - 98,728,971 (-)NCBIGRCm37mm9NCBIm37
MGSCv361598,721,065 - 98,726,574 (-)NCBImm8
Celera15101,042,606 - 101,048,119 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1555.05NCBI
Dhh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27130,050,910 - 130,056,406 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7130,050,910 - 130,056,406 (-)Ensembl
Rnor_6.07140,575,288 - 140,580,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,575,288 - 140,580,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,082,778 - 115,088,273 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,666,984 - 137,672,479 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17137,745,431 - 137,748,567 (-)NCBI
Celera7126,535,827 - 126,541,767 (-)NCBICelera
Cytogenetic Map7q36NCBI
DHH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11240,535,740 - 40,541,123 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,535,740 - 40,541,123 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01239,656,046 - 39,661,439 (+)NCBIMhudiblu_PPA_v0panPan3
DHH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,490,122 - 5,497,144 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,490,441 - 5,494,636 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,762,495 - 40,767,370 (-)NCBI
ROS_Cfam_1.0275,541,256 - 5,548,205 (+)NCBI
ROS_Cfam_1.0 Ensembl275,541,556 - 5,545,696 (+)Ensembl
UMICH_Zoey_3.1275,505,500 - 5,512,442 (+)NCBI
UNSW_CanFamBas_1.0275,495,207 - 5,502,154 (+)NCBI
UU_Cfam_GSD_1.02741,155,104 - 41,159,982 (-)NCBI
Dhh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,274,789 - 66,283,532 (+)NCBI
SpeTri2.0NW_0049365126,885,607 - 6,889,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,330,593 - 45,336,958 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037200,804,838 - 200,811,230 (+)NCBIVero_WHO_p1.0
Dhh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248163,095,849 - 3,104,228 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248163,096,137 - 3,100,882 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system hemolymphoid system nervous system reproductive system
High
Medium
Low
Below cutoff 1 1 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000000199   ⟹   ENSSSCP00000000197
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl515,114,527 - 15,119,577 (-)Ensembl
RefSeq Acc Id: XM_005655550   ⟹   XP_005655607
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1515,114,524 - 15,119,610 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013988251   ⟹   XP_013843705
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1515,114,524 - 15,119,610 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005655607 (Get FASTA)   NCBI Sequence Viewer  
  XP_013843705 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADN43396 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005655607   ⟸   XM_005655550
- Peptide Label: isoform X2
- UniProtKB: F1SJ10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013843705   ⟸   XM_013988251
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000000197   ⟸   ENSSSCT00000000199
Protein Domains
HH_signal   Hint   HintC   HintN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000188 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025076182 UniProtKB/TrEMBL
  ENSSSCG00030051903 UniProtKB/TrEMBL
  ENSSSCG00035046937 UniProtKB/TrEMBL
  ENSSSCG00040033549 UniProtKB/TrEMBL
  ENSSSCG00045009468 UniProtKB/TrEMBL
  ENSSSCG00050077380 UniProtKB/TrEMBL
  ENSSSCG00055027331 UniProtKB/TrEMBL
  ENSSSCG00060025167 UniProtKB/TrEMBL
  ENSSSCG00065054186 UniProtKB/TrEMBL
  ENSSSCG00070030485 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000000197 ENTREZGENE
  ENSSSCP00000000197.3 UniProtKB/TrEMBL
  ENSSSCP00025047106.1 UniProtKB/TrEMBL
  ENSSSCP00030032973.1 UniProtKB/TrEMBL
  ENSSSCP00035025230.1 UniProtKB/TrEMBL
  ENSSSCP00040018974.1 UniProtKB/TrEMBL
  ENSSSCP00045011123.1 UniProtKB/TrEMBL
  ENSSSCP00050047005.1 UniProtKB/TrEMBL
  ENSSSCP00055043132.1 UniProtKB/TrEMBL
  ENSSSCP00060014599.1 UniProtKB/TrEMBL
  ENSSSCP00065032338.1 UniProtKB/TrEMBL
  ENSSSCP00070052319.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000199 ENTREZGENE
  ENSSSCT00000000199.4 UniProtKB/TrEMBL
  ENSSSCT00025105417.1 UniProtKB/TrEMBL
  ENSSSCT00030072306.1 UniProtKB/TrEMBL
  ENSSSCT00035062446.1 UniProtKB/TrEMBL
  ENSSSCT00040045170.1 UniProtKB/TrEMBL
  ENSSSCT00045016056.1 UniProtKB/TrEMBL
  ENSSSCT00050106486.1 UniProtKB/TrEMBL
  ENSSSCT00055054047.1 UniProtKB/TrEMBL
  ENSSSCT00060034103.1 UniProtKB/TrEMBL
  ENSSSCT00065074228.1 UniProtKB/TrEMBL
  ENSSSCT00070061373.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1380.10 UniProtKB/TrEMBL
InterPro Hedgehog UniProtKB/TrEMBL
  Hedgehog_Hint UniProtKB/TrEMBL
  Hedgehog_sig/DD-Pept_Zn-bd_sf UniProtKB/TrEMBL
  Hedgehog_signalling_dom UniProtKB/TrEMBL
  Hint_dom_C UniProtKB/TrEMBL
  Hint_dom_N UniProtKB/TrEMBL
  Hint_dom_sf UniProtKB/TrEMBL
  Intein_N UniProtKB/TrEMBL
KEGG Report ssc:100505406 UniProtKB/TrEMBL
NCBI Gene DHH ENTREZGENE
Pfam HH_signal UniProtKB/TrEMBL
  Hint UniProtKB/TrEMBL
PIRSF Peptidase_C46 UniProtKB/TrEMBL
PRINTS SONICHHOG UniProtKB/TrEMBL
PROSITE INTEIN_N_TER UniProtKB/TrEMBL
SMART HintC UniProtKB/TrEMBL
  HintN UniProtKB/TrEMBL
Superfamily-SCOP SSF51294 UniProtKB/TrEMBL
  SSF55166 UniProtKB/TrEMBL
UniProt A0A4X1WCP1_PIG UniProtKB/TrEMBL
  A0A8D1A534_PIG UniProtKB/TrEMBL
  E2IU42_PIG UniProtKB/TrEMBL
  F1SJ10 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87280 ENTREZGENE