Zdhhc7 (zinc finger, DHHC domain containing 7) - Rat Genome Database

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Gene: Zdhhc7 (zinc finger, DHHC domain containing 7) Mus musculus
Analyze
Symbol: Zdhhc7
Name: zinc finger, DHHC domain containing 7
RGD ID: 1332314
MGI Page MGI
Description: Exhibits protein-cysteine S-palmitoyltransferase activity. Involved in glucose import in response to insulin stimulus; peptidyl-L-cysteine S-palmitoylation; and regulation of protein localization to plasma membrane. Localizes to Golgi apparatus. Is expressed in early conceptus and genitourinary system. Orthologous to human ZDHHC7 (zinc finger DHHC-type palmitoyltransferase 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acyltransferase ZDHHC7; AL024087; DHHC-7; GABA-A receptor-associated membrane protein 2; Gramp2; palmitoyltransferase ZDHHC7; SERZ-beta; zinc finger DHHC domain-containing protein 7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,807,834 - 120,828,211 (-)NCBIGRCm39mm39
GRCm39 Ensembl8120,807,629 - 120,828,221 (-)Ensembl
GRCm388120,081,091 - 120,103,900 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8120,080,890 - 120,101,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv378122,604,995 - 122,625,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv368122,967,072 - 122,987,449 (-)NCBImm8
Celera8124,301,540 - 124,321,926 (-)NCBICelera
Cytogenetic Map8E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:7671812   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15229235   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:18287559   PMID:18596047   PMID:19001095   PMID:20412781   PMID:21677750   PMID:21873635   PMID:22174793   PMID:22988430   PMID:23687301   PMID:25253725   PMID:27380321  
PMID:27875292   PMID:28057756   PMID:28167757   PMID:31183559   PMID:32184353   PMID:33029007  


Genomics

Comparative Map Data
Zdhhc7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,807,834 - 120,828,211 (-)NCBIGRCm39mm39
GRCm39 Ensembl8120,807,629 - 120,828,221 (-)Ensembl
GRCm388120,081,091 - 120,103,900 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8120,080,890 - 120,101,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv378122,604,995 - 122,625,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv368122,967,072 - 122,987,449 (-)NCBImm8
Celera8124,301,540 - 124,321,926 (-)NCBICelera
Cytogenetic Map8E1NCBI
ZDHHC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1684,974,175 - 85,011,535 (-)EnsemblGRCh38hg38GRCh38
GRCh381684,974,175 - 85,011,535 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371685,007,781 - 85,045,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,565,573 - 83,602,642 (-)NCBINCBI36hg18NCBI36
Build 341683,565,572 - 83,602,642NCBI
Celera1669,310,278 - 69,347,352 (-)NCBI
Cytogenetic Map16q24.1NCBI
HuRef1670,760,932 - 70,797,769 (-)NCBIHuRef
CHM1_11686,419,590 - 86,456,676 (-)NCBICHM1_1
Zdhhc7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21948,139,309 - 48,156,673 (-)NCBI
Rnor_6.0 Ensembl1952,733,161 - 52,750,307 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01952,733,161 - 52,750,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01963,480,614 - 63,497,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,406,074 - 50,423,220 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11950,410,954 - 50,428,101 (-)NCBI
Celera1947,395,638 - 47,412,788 (-)NCBICelera
Cytogenetic Map19q12NCBI
Zdhhc7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955541397,748 - 432,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955541398,364 - 426,330 (-)NCBIChiLan1.0ChiLan1.0
ZDHHC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11684,982,607 - 85,019,622 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,982,607 - 85,019,622 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01665,643,906 - 65,681,301 (-)NCBIMhudiblu_PPA_v0panPan3
ZDHHC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1567,554,310 - 67,580,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl567,566,563 - 67,578,556 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha567,568,312 - 67,594,091 (+)NCBI
ROS_Cfam_1.0567,786,224 - 67,812,010 (+)NCBI
UMICH_Zoey_3.1567,802,185 - 67,827,971 (+)NCBI
UNSW_CanFamBas_1.0567,636,627 - 67,662,382 (+)NCBI
UU_Cfam_GSD_1.0568,051,462 - 68,077,242 (+)NCBI
Zdhhc7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934927,421,797 - 27,445,943 (+)NCBI
SpeTri2.0NW_0049366413,175,338 - 3,199,487 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl63,786,325 - 3,899,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.163,786,330 - 3,817,960 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.264,215,849 - 4,247,456 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZDHHC7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1570,379,228 - 70,419,885 (-)NCBI
ChlSab1.1 Ensembl570,379,179 - 70,401,139 (-)Ensembl
Vero_WHO_p1.0NW_0236660475,324,504 - 5,366,536 (+)NCBI
Zdhhc7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247461,715,907 - 1,740,414 (-)NCBI

Position Markers
RH129286  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388120,081,196 - 120,081,400UniSTSGRCm38
MGSCv378122,605,096 - 122,605,300UniSTSGRCm37
Celera8124,301,641 - 124,301,845UniSTS
Cytogenetic Map8E1UniSTS
RH125474  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388120,081,574 - 120,081,794UniSTSGRCm38
MGSCv378122,605,474 - 122,605,694UniSTSGRCm37
Celera8124,302,019 - 124,302,239UniSTS
Cytogenetic Map8E1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889000000130800000Mouse
1357494Obsty2_mobesity 2 (mouse)Not determined895518613129018580Mouse
12880431Fgf23lq2_mFGF23 serum level QTL 2 (mouse)896900000129401213Mouse
11252141Fdr2_mfat response to dietary restriction 2 (mouse)897663894129401213Mouse
1301481Lith11_mlithogenic gene 11 (mouse)Not determined897836895129401213Mouse
1301080Sluc9_msusceptibility to lung cancer 9 (mouse)Not determined899101792129401213Mouse
1302105Im1_mImmunoregulatory 1 (mouse)Not determined899101792129401213Mouse
4141435Fbtq3_mfemoral bone trait QTL 3 (mouse)Not determined8100238570129401213Mouse
1301316Dntcs1_mdental caries susceptibility 1 (mouse)Not determined8102716921127055036Mouse
11532691Sluc38_msusceptibility to lung cancer 38 (mouse)8104307238129401213Mouse
11532692Sluc38a_msusceptibility to lung cancer 38a (mouse)8104307238129401213Mouse
14746994Manh65_mmandible shape 65 (mouse)8105762890129401213Mouse
10412273Fcd1_mfunctional capillary density 1 (mouse)Not determined8109688333129401213Mouse
10412274Leci1_mleukocyte endothelial cell interactions 1 (mouse)Not determined8109688333129401213Mouse
12904938Edlmmq7_mextensor digitorum longus muscle mass QTL 7 (mouse)8110755016129401213Mouse
12904960Gmmq6_mgastrocnemius muscle mass QTL 6 (mouse)8110755016129401213Mouse
4141546Mrdq3_mmodifier of retinal degeneration QTL 3 (mouse)Not determined113712788125329141Mouse
26884375Skwq2_mskull length QTL 2, 5 week (mouse)8120000000131200000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1089
Count of miRNA genes:603
Interacting mature miRNAs:735
Transcripts:ENSMUST00000034280, ENSMUST00000123186, ENSMUST00000124044, ENSMUST00000141886, ENSMUST00000150444
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF059580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY166673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC075666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034280   ⟹   ENSMUSP00000034280
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl8120,080,890 - 120,101,482 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123186
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl8120,092,975 - 120,101,072 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124044
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl8120,085,222 - 120,088,075 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141886
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl8120,085,412 - 120,088,268 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150444
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl8120,082,403 - 120,086,835 (-)Ensembl
RefSeq Acc Id: NM_133967   ⟹   NP_598728
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398120,807,834 - 120,828,211 (-)NCBI
GRCm388120,081,095 - 120,101,472 (-)NCBI
MGSCv378122,604,995 - 122,625,372 (-)RGD
Celera8124,301,540 - 124,321,926 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248257   ⟹   XP_011246559
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398120,807,834 - 120,818,967 (-)NCBI
GRCm388120,081,091 - 120,103,900 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_598728   ⟸   NM_133967
- UniProtKB: Q91WU6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011246559   ⟸   XM_011248257
- Peptide Label: isoform X1
- UniProtKB: Q91WU6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034280   ⟸   ENSMUST00000034280
Protein Domains
DHHC

Promoters
RGD ID:8668449
Promoter ID:EPDNEW_M12255
Type:initiation region
Name:Zdhhc7_1
Description:Mus musculus zinc finger, DHHC domain containing 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388120,101,294 - 120,101,354EPDNEW
RGD ID:6843902
Promoter ID:MM_KWN:55929
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000068154
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368122,611,496 - 122,611,996 (-)MPROMDB
RGD ID:6842583
Promoter ID:MM_KWN:55931
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK037392_A130014A01RIK,   OTTMUST00000068152,   OTTMUST00000068153
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368122,625,221 - 122,628,017 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2142662 AgrOrtholog
Ensembl Genes ENSMUSG00000031823 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000034280 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034280 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Palmitoyltrfase_DHHC UniProtKB/Swiss-Prot
KEGG Report mmu:102193 UniProtKB/Swiss-Prot
MGD MGI:2142662 ENTREZGENE
NCBI Gene 102193 ENTREZGENE
Pfam DHHC UniProtKB/Swiss-Prot
PhenoGen Zdhhc7 PhenoGen
PROSITE DHHC UniProtKB/Swiss-Prot
UniProt Q91WU6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3TC41 UniProtKB/Swiss-Prot
  Q6EMK2 UniProtKB/Swiss-Prot
  Q8K1H6 UniProtKB/Swiss-Prot