Zdhhc9 (zinc finger DHHC-type palmitoyltransferase 9) - Rat Genome Database

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Gene: Zdhhc9 (zinc finger DHHC-type palmitoyltransferase 9) Rattus norvegicus
Analyze
Symbol: Zdhhc9
Name: zinc finger DHHC-type palmitoyltransferase 9
RGD ID: 1561389
Description: Predicted to enable Ras palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC302808; membrane-associated DHHC9 zinc finger protein; palmitoyltransferase ZDHHC9; zinc finger, DHHC domain containing 9; zinc finger, DHHC-type containing 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X127,352,340 - 127,388,245 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,478,111 - 129,514,060 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X133,048,918 - 133,084,810 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X130,575,263 - 130,611,214 (-)NCBIRnor_WKY
Rnor_6.0X135,005,171 - 135,041,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,537,438 - 134,573,364 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX126,302,789 - 126,338,662 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16000296   PMID:16647879   PMID:23034182  


Genomics

Comparative Map Data
Zdhhc9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X127,352,340 - 127,388,245 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,478,111 - 129,514,060 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X133,048,918 - 133,084,810 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X130,575,263 - 130,611,214 (-)NCBIRnor_WKY
Rnor_6.0X135,005,171 - 135,041,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,537,438 - 134,573,364 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX126,302,789 - 126,338,662 (-)NCBICelera
Cytogenetic MapXq36NCBI
ZDHHC9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X129,803,288 - 129,843,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX129,803,288 - 129,843,909 (-)EnsemblGRCh38hg38GRCh38
GRCh37X128,937,264 - 128,977,862 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X128,766,593 - 128,805,554 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X128,664,449 - 128,703,408NCBI
CeleraX129,323,767 - 129,364,414 (-)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX118,338,764 - 118,378,757 (-)NCBIHuRef
CHM1_1X128,848,613 - 128,889,262 (-)NCBICHM1_1
T2T-CHM13v2.0X128,122,064 - 128,162,666 (-)NCBIT2T-CHM13v2.0
Zdhhc9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X47,260,844 - 47,297,792 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX47,260,846 - 47,297,755 (-)EnsemblGRCm39 Ensembl
GRCm38X48,171,967 - 48,208,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX48,171,969 - 48,208,878 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X45,525,148 - 45,561,879 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X44,416,598 - 44,453,310 (-)NCBIMGSCv36mm8
CeleraX35,674,299 - 35,710,725 (-)NCBICelera
Cytogenetic MapXA4NCBI
Zdhhc9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554735,174,563 - 5,208,767 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554735,174,575 - 5,208,767 (+)NCBIChiLan1.0ChiLan1.0
ZDHHC9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X129,230,556 - 129,270,665 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX129,230,571 - 129,270,665 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X118,932,986 - 118,973,238 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ZDHHC9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,011,072 - 101,096,394 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX100,996,607 - 101,043,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,184,996 - 87,270,387 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X102,862,545 - 102,948,146 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX102,864,567 - 102,896,674 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,280,828 - 100,366,232 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,127,017 - 102,212,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X101,904,811 - 101,990,352 (-)NCBIUU_Cfam_GSD_1.0
Zdhhc9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X99,244,189 - 99,275,735 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364791,711,713 - 1,741,167 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364791,711,756 - 1,743,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX106,401,245 - 106,436,014 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X106,397,139 - 106,436,103 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X122,170,189 - 122,205,037 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZDHHC9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X105,082,531 - 105,120,802 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606542,495,912 - 42,536,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zdhhc9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247979,023,833 - 9,060,855 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247979,027,316 - 9,060,321 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zdhhc9
90 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:723
Count of miRNA genes:287
Interacting mature miRNAs:375
Transcripts:ENSRNOT00000006484
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 41 41 41 74 35 37 11
Low 15 16 19 8 11 4 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006484   ⟹   ENSRNOP00000006484
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX127,352,345 - 127,388,245 (-)Ensembl
Rnor_6.0 EnsemblX135,005,123 - 135,041,027 (-)Ensembl
RefSeq Acc Id: NM_001039016   ⟹   NP_001034105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X127,352,343 - 127,388,245 (-)NCBI
Rnor_6.0X135,005,171 - 135,040,996 (-)NCBI
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBI
RGSC_v3.4X134,537,438 - 134,573,364 (-)RGD
CeleraX126,302,789 - 126,338,662 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257521   ⟹   XP_006257583
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X127,352,340 - 127,387,957 (-)NCBI
Rnor_6.0X135,005,171 - 135,040,730 (-)NCBI
Rnor_5.0X135,081,376 - 135,116,885 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034105 (Get FASTA)   NCBI Sequence Viewer  
  XP_006257583 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI29071 (Get FASTA)   NCBI Sequence Viewer  
  AAX73388 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001034105   ⟸   NM_001039016
- UniProtKB: A1L1I1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257583   ⟸   XM_006257521
- Peptide Label: isoform X1
- UniProtKB: Q2TGJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006484   ⟸   ENSRNOT00000006484
Protein Domains
DHHC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2TGJ9-F1-model_v2 AlphaFold Q2TGJ9 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702010
Promoter ID:EPDNEW_R12534
Type:initiation region
Name:Zdhhc9_1
Description:zinc finger, DHHC-type containing 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X135,041,012 - 135,041,072EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561389 AgrOrtholog
BioCyc Gene G2FUF-1138 BioCyc
Ensembl Genes ENSRNOG00000004581 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006484 ENTREZGENE
  ENSRNOP00000006484.6 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006484 ENTREZGENE
  ENSRNOT00000006484.7 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7461054 IMAGE-MGC_LOAD
InterPro ZDHHC9 UniProtKB/TrEMBL
  Znf_DHHC UniProtKB/TrEMBL
KEGG Report rno:302808 UniProtKB/TrEMBL
MGC_CLONE MGC:156472 IMAGE-MGC_LOAD
NCBI Gene 302808 ENTREZGENE
PANTHER PTHR22883:SF71 UniProtKB/TrEMBL
Pfam zf-DHHC UniProtKB/TrEMBL
PhenoGen Zdhhc9 PhenoGen
UniProt A1L1I1 ENTREZGENE, UniProtKB/TrEMBL
  F7F533_RAT UniProtKB/TrEMBL
  Q2TGJ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-11 Zdhhc9  zinc finger DHHC-type palmitoyltransferase 9  Zdhhc9  zinc finger, DHHC-type containing 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-17 Zdhhc9  zinc finger, DHHC-type containing 9  Zdhhc9  zinc finger, DHHC domain containing 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Zdhhc9  zinc finger, DHHC domain containing 9  LOC302808  membrane-associated DHHC9 zinc finger protein  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC302808  membrane-associated DHHC9 zinc finger protein      Symbol and Name status set to provisional 70820 PROVISIONAL